070300|化学专业硕士研究生指导教师
姓名 孔秀琪 性别 女
民族 汉 出生年月
学历|学位 | 专业技术职务 讲师
行政职务
联系电话 ** 移动电话
邮箱 myfriend100@163.com
通讯地址|邮编 济南大学逸夫楼南楼A222|
招生方向(领域) 02分析化学
研究领域、学习工作经历、学术兼职等情况 2015.07-至今 济南大学 讲师
2012.09-2015.06 南开大学 化学生物学 博士
2009.09-2012.06 南开大学 化学生物学 硕士
2005.09-2009.06 济南大学 生物技术 学士


代表性科研成果及奖励：
（包括项目、鉴定、论文、专著、专利等) 本人从事小分子荧光探针的研究，主要围绕肿瘤相关的生物酶，抗肿瘤药物与荧光探针相结合构建诊断型荧光探针和诊疗一体化荧光前药。截至目前主持基金包括国家自然科学基金青年项目（资助经费25万）山东省自然科学培养基金项目（资助经费4万）。
代表论文：
Xiuqi Kong; Baoli Dong; Nan Zhang; Chao Wang; Xuezhen Song; Weiying Lin*. Dual turn-on fluorescence signal-based controlled release system for real-time monitoring of drug release dynamics in living cells and tumor tissues. Theranostics 2018; 8(3), 800-811.
Xiuqi Kong, Junling Yin, Min Li, Linlin Zhu, Baoli Dong, Yanyan Ma, Weiying Lin^*. Simultaneously imaging of SO2 in lysosomes and mitochondria based on a dual organelle-targeted ?uorescent probe. Sensors and Actuators B: Chemical; 2019;292,80-87.
Xiuqi Kong, Min Li, Baoli Dong, Yaguang Yin, Wenhui Song, and Weiying Lin^*. An Ultrasensitivity Fluorescent Probe Based on the ICT-FRET Dual Mechanisms for Imaging β?Galactosidase in Vitro and ex Vivo. Analytical Chemistry, 2019, doi: 10.1021/acs.analchem.9b03639.
Xiuqi Kong, Baoli Dong, Nan Zhang, Chao Wang, Xuezhen Song, Weiying Lin*. A unique red-emitting two-photon ?uorescent probe with tumor-speci?city for imaging in living cells and tissues. Talanta, 2017, 174: 357-364.
Xiuqi Kong, Min Li, Baoli Dong, Nan Zhang, Wenhui Song, Yaru Lu and Weiying Lin*. A near-infrared and two-photon dual-mode ?uorescent probe for the colorimetric monitoring of SO₂ in vitro and in vivo. Analyst, 2019, 144, 4371-4379.
Xiuqi Kong; Baoli Dong; Chao Wang; Nan Zhang; Wenhui Song; Weiying Lin*. A novel mitochondria-targeted fluorescent probe for imaging hydrazine in living cells, tissues and animals Journal of Photochemistry and Photobiology A: Chemistry 2018; 356, 321-328.
Keyin Liu^(#), Xiuqi Kong^(#) (co-author), Yanyan Ma, Weiying Lin^*. Rational design of a robust ?uorescent probe for detecting endogenous carbon monoxide in living zebrafish embryos and mouse tissues. Angewandte Chemie-International Edition, 2017; 56(43): 13489-13492.
Keyin Liu^(#); Xuqi Kong^(#) (co-author); Yanyan Ma; Weiying Lin^*. Preparation of a Nile Red-Pd based fluorescent CO probe and its imaging applications in vitro and in vivo. Nature Protocol; 2018; 13(5):1020-1033.

教学及研究生培养情况 研究生课程《靶向生物荧光探针制备技术》；
本科生课程《PCR技术》双语

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