070300|化学专业硕士研究生指导教师
姓名 田明刚 性别 男
民族 汉 出生年月 1990-04
学历|学位 博士研究生|博士 专业技术职务 讲师
行政职务 教师
联系电话 ** 移动电话 **
邮箱 ifp_tianmg@ujn.edu.cn
通讯地址|邮编 山东省济南市南辛庄西路336号 逸夫楼A216|
招生方向(领域) 02分析化学,03有机化学,05高分子化学与物理
研究领域、学习工作经历、学术兼职等情况 2007.09-2011.07 山东大学 学士
2012.09-2017.07 山东大学 博士

代表性科研成果及奖励：
（包括项目、鉴定、论文、专著、专利等) 发表论文：
济南大学工作
1. Minggang Tian, Chuang Liu, Baoli Dong, Yujing Zuo, Weiying Lin*, A dual-site controlled ratiometric probe revealing the simultaneous downregulation of pH in lysosomes and cytoplasm during autophagy,Chem. Commun. 2019, 55, 10440-10443.
2. Minggang Tian, Yanyan Ma, Weiying Lin*, Fluorescent probes for the visualization of cell viability,Acc. Chem. Res. 2019, 52, 2147−2157.
3. Minggang Tian, Jie Sun, Baoli Dong, Weiying Lin*, Unique pH-sensitive RNA binder for ratiometric visualization of cell apoptosis,Anal. Chem. 2019, 91, 10056−10063.
4.Minggang Tian, Jie Sun, Baoli Dong, Weiying Lin*, Construction of mitochondria-nucleolus shuttling fluorescent probe for the reversible detection of mitochondrial membrane potential,Sensor. Actuat. B 2019, 292, 16-23.
5.Minggang Tian, Jie Sun, Baoli Dong, Weiying Lin*, Dynamically monitoring cell viability in a dual‐ color mode: construction of an aggregation/monomer‐ based probe capable of reversible mitochondria‐ nucleus migration,Angew. Chem. Int. Ed. 2018, 57, 16506 –16510.
6.Minggang Tian, Jie Sun, Yonghe Tang, Baoli Dong, Weiying Lin*, Discriminating live and dead cells in dual-color mode with a two-photon fluorescent probe based on ESIPT mechanism.Anal. Chem. 2018, 90, 998−1005.
前期工作
7. Minggang Tian, Yong Liu, Yuming Sun, Ruoyao Zhang, Ruiqing Feng, Ge Zhang, Lifang Guo, Xuechen Li, Xiaoqiang Yu, *Jing Zhi Sun*, Xiuquan He*, A single fluorescent probe enables clearly discriminating and simultaneously imaging liquid-ordered and liquiddisordered microdomains in plasma membrane of living cells,Biomaterials 2017, 120, 46-56.
8.Minggang Tian, Yuming Sun, Lifang Guo, Ruoyao Zhang, Ge Zhang, Ruiqing Feng, Xuechen Li, Huamiao Zhang , Li He, Xiaoqiang Yu*, Xiuquan He*, A small-structure twophoton platform equipped with weak electron donor: Development of permeable two-photon probes for lysosomes and mitochondria in living cells.Sensor. Actuat. B 2017, 243, 955–962.
9.Minggang Tian, Fuqiang Guo, Yuming Sun, Weijia Zhang, Fang Miao, Yong Liu, Guofen Song, Cheuk-Lam Ho, Xiaoqiang Yu,* Jing Zhi Sun* and Wai-Yeung Wong*, A fluorescent probe for intracellular cysteine overcoming the interference by glutathione,Org. Biomol. Chem. 2014, 12, 6128–6133.
指导学生工作
10. Jie Sun, Minggang Tian, Weiying Lin*, A two-photon excited red-emissive probe for imaging mitochondria with high fidelity and its application in monitoring mitochondrial depolarizationviaFRET,Analyst, 2019,144, 2387-2392.
11.Jie Sun, Minggang Tian, Weiying Lin*, Monitoring mitochondrial membrane potential by FRET: Development of fluorescent probes enabling ΔΨm-Dependent subcellular migration, Analytica Chimica Acta DOI:10.1016/j.aca.2019.11.015.
12. Chuang Liu, Minggang Tian, Weiying Lin*, Unique Polarity-Sensitive Photothermal Sensitizer Revealing Down-regulated Mitochondrial Polarity During Photo-Induced Cell Death, J. Mater. Chem. BDOI: 10.1039/C9TB02233C.
科研项目：
双色区分成像死活细胞的单双光子荧光探针的研制 山东省博士基金 7万
细胞核靶向次氯酸荧光探针的构建及其在生物成像中的应用 国家自然科学基金 25万

教学及研究生培养情况 本科生课程：有机化学II 化学制药工艺
研究生课程：荧光分析原理

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