100701|药物化学专业硕士研究生指导教师
姓名 宋智梅 性别 女
民族 满族 出生年月 ?1969-03-08
学历|学位 研究生|硕士 专业技术职务 高工
行政职务
联系电话 ** 移动电话 **
邮箱 chm_songzm@ujn.edu.cn
通讯地址|邮编 济南市市中区南辛庄西路336号济南大学生物科学与技术学院|
招生方向(领域) 药物化学
研究领域、学习工作经历、学术兼职等情况 学习简历
1990，9-1994，7 沈阳药科大学，微生物制药，本科
2006，9-2011，7 山东大学，药剂学，硕士
工作简历
1994，7-2005,1 东北第六制药厂，高级工程师
2005，1-至今 济南大学，高级实验师

代表性科研成果及奖励：
（包括项目、鉴定、论文、专著、专利等) 承担项目
1山东省高等学校教师科研计划、J14LM01 、2014/3-2017/3、阿霉素载药半乳糖修饰PEG类线-树形嵌段聚合物纳米粒的研究、5.6万元、在研、参与。
2山东省优秀中青年奖励基金、BS2011CL006、抗癌药物紫杉醇PEG-PCL多不饱和脂肪酸衍生化纳米粒制剂的研究、2011/7-2014/7、6万元、已结题、参与。
3. 山东省自然科学基金高校联合专项、ZR2016BL15、叶酸介导温度-还原敏感紫杉醇-壳聚糖缀合高分子前药的研究、2016/11-2018/12、5万元，在研，参与
获奖情况
姜黄素聚乙二醇-聚酯载药系统研究，山东省高等学校科学技术奖三等奖，2016.12，第二位
济南大学科研成果三等奖三项，第二位
主要科研成果
1) Zhimei Song, Jingjie Sun, Peizong Deng, Feilong Zhou, Hongmei Xu, Yi Wen. Fangfang Teng, Di Ge, Runliang Feng^*, Oligochitosan-pluronic 127 conjugate for delivery of honokiol, Artificial cells, nanomedicine, and Biotechnology, 2018, 1-11 (Epub, SCI, IF=5.605)
2) Runliang, Feng, Peizong Deng, Feilong Zhou, Sijia Feng, Zhimei Song^*, Pluronic F127-cyclodextrin conjugate micelles for encapsulation of honokiol." Journal of Nanoparticle Research, 2018, 20(10): 261 (SCI, IF=2.17)
3) Runliang Feng, Wenxia Zhu, Wei Chu, Fangfang Teng, Ning Meng, Peizong Deng, Zhimei Song ^*. Y-shaped folic acid-conjugated PEG-PCL copolymeric micelles for delivery of curcumin. Anti-Cancer Agents in Medicinal Chemistry, 2017, 4: 599-607 (SCI, IF=2.598)
4) Zhimei Song, Peizong Deng, Fangfang Teng, Feilong Zhou, Wenxia Zhu, Runliang Feng^*. Development on PEG-modified Poly (Amino Acid) Copolymeric Micelles for Delivery of Anticancer Drug." Anti-Cancer Agents in Medicinal Chemistry 2017, 17(6): 784-801. (SCI, IF=2.598)
5) Runliang Feng, Peizong Deng, Fangfang Teng and Zhimei Song*, Recent Development of Copolymeric Delivery System for Anticancer Agents Based on Cyclodextrin Derivatives, Anti-Cancer Agents in Medicinal Chemistry, 2016, 16: 299-308 (SCI, IF=2.722)
6) Wenxia Zhu^(#), Zhimei Song, Peng Wei, Ning Meng, Fangfang Teng, Fengying Yang, Na Liu, Runliang Feng(通讯), Y-shaped biotin-conjugated poly (ethylene glycol)-poly (epsilon-caprolactone) copolymer for the targeted delivery of curcumin, Journal of Colloid and Interface Science, 2015, 443: 1-7(SCI，IF=3.552)
Zhimei Song^(#), Wenxia Zhu, Jiarong Song, Peng Wei, Fengying Yang, Na Liu, Runliang Feng(通讯), Linear-dendrimer Type Methoxy-poly (ethylene glycol)–b-poly (e-caprolactone) Copolymer Micelles for the Delivery of Curcumin, Drug Delivery, 2015, 22(1): 58-68 (SCI, IF=2.202)
8) Zhimei Song^(#), Wenxia Zhu, Fengying Yang, Na Liu, Runliang Feng(通讯), Preparation, characterization, in vitro release, and pharmacokinetic studies of curcumin-loaded mPEG–PVL nanoparticles, 2015, Polymer Bulletin, 72: 75-91(SCI, IF=1.491)
9) Zhimei Song^(#), Wenxia Zhu, Na Liu, Fengying Yang, Runliang Feng(通讯), Linolenic acid-modified PEG-PCL micelles for curcumin delivery, International Journal of Pharmaceutics, 2014, 471: 312-321(SCI, IF=3.785)
10) Runliang Feng^(#), Wenxia Zhu, Zhimei Song(通讯), Liyan Zhao, Guangxi Zhai, Novel star-type methoxy-poly(ethylene glycol) (PEG)–poly(e-caprolactone) (PCL) copolymeric nanoparticles for controlled release of curcumin, Journal of Nanoparticle Research, 2013, 15: 1748-1759 (SCI，IF=2.175)
11) Runliang Feng^(#)(通讯), Zhimei Song, Guangxi Zhai, Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles, International Journal of Nanomedicine, 2012, 7: 4089-4098 ( SCI，IF=3.13)
12) Zhimei Song^(#), Runliang Feng^(#), Min Sun, Chenyu Guo, Yan Gao, Lingbing Li, Guangxi Zhai(通讯)， Curcumin-loaded PLGA-PEG-PLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo, Journal of Colloid and Interface Science, 2011, 354: 116–123(SCI，IF=3.066)
13) 冯润良, 宋智梅, 间硝基苯乙炔的制备工艺, 2011.7, 中国, ZL9.5
14) Min Sun^(#), Yan Gao, Chenyu Guo, Fengliang Cao, Zhimei Song, Yanwei Xi, Aihua Yu, Aiguo Li and Guangxi Zhai(通讯), Enhancement of transport of curcumin to brain in mice by poly(n-butylcyanoacrylate) nanoparticles, Journal of Nanoparticle Research, 2010, 12(8): 3111-3122 (SCI, IF=2.478)
15) 冯润良, 宋智梅, N-氨基哌啶盐酸盐的制备方法, 2010.12, 中国, ZL 7.0

教学及研究生培养情况 主要从事《药物化学》、《药剂学》和《药物分析》、《制药综合实验》等本科实验教学工作。

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