100701|药物化学专业硕士研究生指导教师
姓名 周洁 性别 女
民族 汉族 出生年月 1981-03
学历|学位 研究生|博士 专业技术职务 副教授
行政职务
联系电话 移动电话 **
邮箱 zhoujie8761@163.com
通讯地址|邮编 济南市中区南辛庄西路336号|250012
招生方向(领域) 03天然药物活性成分的分离和结构修饰
研究领域、学习工作经历、学术兼职等情况 研究领域：
中药学与分子生药学
学习工作经历：
2015/11至今济南大学 生物科学与技术学院，副教授
2011/09-2015/10 山东省科学院，副研究员
2008/09-2011/07 中国中医科学院 中药学 博士
学术兼职：
山东中医药大学硕士研究生导师；《中国现代中药》杂志编委；山东农学会药用植物专业委员会特聘学术专家；中国中药协会中药资源多样性与生态经济专业委员会委员

代表性科研成果及奖励：
（包括项目、鉴定、论文、专著、专利等) 主要从事中药资源与分子生药学研究，主要研究方向为道地药材形成机制及药用植物次生代谢调控研究。
海外经历
曾留学海外，师从在国际著名植物学专家Johannes van Staden教授，从事中药资源相关课题研究。
科研情况
(1) 主持国家、省部级等各级项目20余项，总经费400万元。
1、国家自然科学基金青年项目（**）：2014/01-2016/12
2、国家自然科学基金面上项目（**）：2017/01-2020/12
3、国家重点研发计划子课题 （2017YFC**）：2018/01-2022/12
4、国家科技基础性工作专项项目计划子课题 （2015FY111500)：2015.5-2020.5
5、山东省自然科学基金青年项目（ZR2013HQ037）：2014/08-2016/12
6、山东省重点研发计划（2015GSF119026）：2015/01-2017/12
7、山东省重点研发计划（2017GSF19115）：2017/05-2019/04
8、国家药品标准提高暨2015版药典科研项目：2012/06-2014/12
9、第四次全国中药资源普查山东文登试点普查项目（2015-55）：2014/05-2017/05
10、第四次全国中药资源普查山东昌乐普查项目（2017-21）：2017/09-2019/05
11、第四次全国中药资源普查山东平原普查项目（2018-21）：2018/09-2019/05
12、中央本级重大增减支项目（；；）
13、山东省重大科技创新工程子课题(2017CXGC1303): 2017/01-2019/12
发表论文情况
以第一作者或通讯作者发表文章57篇，其中SCI收录22篇。
(1) Jie Zhou, Lan-ping Guo, Ji Zhang, Shu-feng Zhou, Guang Yang, Man-xi Zhao, Lu-qi Huang. Effects of LaCl3 on photosynthesis and the accumulation of tanshinones and salvianolic acids in Salvia miltiorrhiza seedlings. Journal of Rare Earths, 2011, 29 (5): 494-498
(2) Jie Zhou, Johannes Van Staden, Lan-ping Guo, Lu-qi Huang. Smoke-water improves shoot growth and Indigo accumulation in shoot of Isatis indigotica seedlings. South African Journal of Botany, 2011, 77: 787-789
(3) Jie Zhou, Manoj Gajanan Kulkarni, Lu-qi Huang, Lan-ping Guo, Johannes Van Staden. Effects of temperature, light, nutrients and smoke-water on seed germination and seedling growth of Astragalus membranaceus, Panax notoginseng and Magnolia officinalis – highly traded Chinese medicinal plants. South African Journal of Botany, 2012, 79: 62-70
(4) Jie Zhou, Lei Fang, Xuan Li, Lan-ping Guo, Lu-qi Huang. Jasmonic Acid (JA) acts as a signal molecule in LaCl3-induced Baicalin synthesis in Scutellaria baicalensis seedlings. Biological Trace Element Research. 2012, 148: 392-395
(5) Jie Zhou, Xiao Wang, Lei Fang, Lan-ping Guo, Lu-qi Huang. Comparison of the volatile compounds of crude and processed Atractylodis Rhizome analyzed by GC-MS. African Journal of Pharmacy and Pharmacology. 2012, 6 (28): 2155-2160
(6) Jie Zhou, Lei Fang, Xiao Wang, Lanping Guo, Luqi Huang. Effects of smoke-water on photosynthetic characteristics of Isatis indigotica seedlings. Sustainabe Agriculture Research. 2013, 2 (2): 24-28
(7) Jie Zhou, Lei Fang, Xiao Wang, Lanping Guo, Luqi Huang. La dramatically enhances the accumulation of tanshinones in Salvia miltiorrhiza hairy root cultures. Earth Science Research. 2013, 2 (1): 187-192
(8) Lei Fang, Wemao Gen, Jie Zhou*, Ruimin Cao, Zhiwei Wang, JinLian Li and Yanling Geng. Preparative Separation and Purification of Flavonoids from Ephedra sinica Stapf. by High-Speed Counter-Current Chromatography. Asian Journal of Chemistry, 2014, 26(24): 1-4
(9) Wenhua Jia, Hongkai Xie, Jie Zhou*, Xiao Wang*, Xiuli Ma, Luqi Huang. Water-compatible molecularly imprinted polymers for selective solidphase extraction of dencichine from the aqueous extract of Panaxnotoginseng. Journal of Chromatography B, 2016, 1008: 225-233
(10) Lei Fang, Shan-Ming Tian, Jie Zhou*, Yun-Liang Lin, Zhi-Wei Wang, Xiao Wang. Melaxillines A and B, monoterpenoid indole alkaloids from Melodinus axillaris. Fitoterapia, 2016, 115: 173-176.
(11) Jie Zhou*, Jin-Hong Feng, Lei Fang*. A novel monoterpenoid indole alkaloid with anticancer activity from Melodinus khasianus. Bioorganic & Medicinal Chemistry Letters, 2017, 27:893-896.
(12) Lei Fang, Jialian Li, Jie Zhou*, Isolation and Purification of Three Ecdysteroids fromthe Stems of Diploclisia glaucescens by High-Speed Countercurrent Chromatography and TheirAnti-Inflammatory Activities In Vitro molecules, 2017, 22 (8): 1-7
(13) Jie Zhou, Jin-Hong Feng, Lei Fang*, A novel monoterpenoid indole alkaloid with anticancer activity from Melodinus khasianus. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 893-896.
(14) Lei Fang, Jie Zhou*, Rapid screening and preparative isolation of antioxidants from Alpinia officinarum Hance using HSCCC coupled with DPPH-HPLC assay and evaluation of their antioxidant activities. Journal of Analytical Methods in Chemistry, 2018
(15) Lei Fang, Xiu-Qing Song, Tian-Tian He, Kong-Kai Zhu, Jin-Hai Yu, Jin-Tong Song, Jie Zhou*, Hua Zhang, Two new polyketides from the roots of Stemona tuberosa, Fitoterapia 2018, 129: 150–153
(16) Lei Fang, ZhongYing Fang, Peng Zhoub, Jie Bao, Jin-Hai Yua, Jin-Tong Song, Jie Zhou, Hua Zhang, Anti-inflammatory lignans from Melodinus suaveolens, Phytochemistry Letters, 2018, 26, 134–137
(17) Jie Zhou, Zixin Xu, Zhifang Ran, Lei Fang* and Lanping Guo, Effects of Smoke-Water and Smoke-Derived Butenolide on Accumulation of Phenolic Acids in Cultured Hairy Roots of Salvia Miltiorrhiza Bunge. Bangladesh Journal of Botany, 2018, 47(3): 479-485
(18) Jie Zhou, Zhifang Ran, Zixin Xu, Qian Liu, Min Huang, Lei Fang, Lanping Guo, Effects of smoke-water and smoke-isolated karrikinolide on tanshinones production in Salvia miltiorrhiza hairy roots. South African Journal of Botany, 2018,119, 265-270.
(19) Jie Zhou, Zhifang Ran, Qian Liu, Zixin Xu, Yanghui Xiong, Lei Fang?, Lanping Guo?, Jasmonic acid serves as a signal role in smoke-isolated butenolide induced tanshinones biosynthesis in Salvia miltiorrhiza hairy root. South African Journal of Botany, 2019, 121, 355-359.?
(20) Jie Zhou, Zi-xin Xu, Hui Sun and Lan-ping Guo*, Smoke-Isolated Karrikins Stimulated Tanshinones Biosynthesis in Salvia miltiorrhiza through Endogenous Nitric Oxide and Jasmonic Acid. Molecules, 2019, 24, 1229.
(21) Jie Zhou, Si-Yu Du, Hong-Jing Dong, Lei Fang* and Jin-Hong Feng*, Preparative Separation of Monoterpenoid Indole Alkaloid Epimers from Ervatamia yunnanensis Tsiang by pH-Zone-Refining Counter-Current Chromatography Combined with Preparative High-Performance Liquid Chromatography. Molecules, 2019, 24,1316.
(22) Jie Zhou*, Zhi-fang Ran, Xiaotong Yang and Jia Li*, Postharvest UV-B Irradiation Stimulated Ginsenoside Rg₁ Biosynthesis through Nitric Oxide (NO) and Jasmonic Acid (JA) in Panax quinquefolius Roots. Molecules, 2019, 24, 1462.


教学及研究生培养情况 先后承担本科生《药用植物学》、《仪器分析实验》、《药物发展前沿》、《专业导论》；通选课《本草中国—遇见最美植物药》以及研究生课程《科技论文写作》、《专业英语》等课程的讲授工作，并完成了学院规定的教学工作量。先后两次获得济南大学教学贡献奖，主持校级教研项目1项，以第一作者发表教研论文4篇。2017年被聘为济南大学第七届本科教学督导员，并被评为优秀督导员。

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