一、基本情况
张志岳，博士，山东大学药学院教授，药剂学专业博士生导师。2017年获得山东大学“齐鲁青年****”人才称号。博士毕业于比利时根特大学（Ghent University, Belgium），期间主要从事多功能聚合物以及聚合物修饰金纳米粒在药物传递方面的研究工作。截止目前，已在Angewandte Chemie International Edition, Advanced Functional Materials, Chemistry of Materials等药剂学/材料化学领域权威学术期刊发表SCI论文16篇。
通讯地址：山东省济南市文化路44号，山东大学药学院药剂教研室
TEL: **
E-mail: zhiyue.zhang@sdu.edu.cn
二、研究领域
方向1：基于多功能聚合物的合成、修饰制备新型药物传递载体。
方向2：靶向修饰纳米粒作为药物传递系统的研究。
三、工作及学习经历
2018.10 - 至今， 山东大学 药学院， 教授、博士生导师
2016.10-2018.09，比利时根特大学（Ghent University, Belgium），博士后研究员
2012.10-2016.05，比利时根特大学（Ghent University, Belgium），博士
2009.09-2012.06，山东大学，硕士
2005.09-2009.06，山东大学，学士
四、社会兼职
中国药学会高级会员
美国American Chemical Society 会员
五、承担课题
1、山东大学“齐鲁青年****”科研启动基金；
2、Special Research Fund Ghent University-Postdoctoral fellowship at Ghent University
3、Special Research Fund Ghent University-CSC co –funding at Ghent University
4、国家建设高水平大学公派研究生项目
六、获奖情况
1、山东大学“齐鲁青年****”，2017年
2、FWO (Fonds Wetenschappelijk Onderzoek) conference travel grant, 2015, UGent, Belgium
3、FWO (Fonds Wetenschappelijk Onderzoek) conference travel grant, 2014, UGent, Belgium
七、 代表性学术论文 （限10篇）
1）Zhang, Z.; Maji, S.; Antunes, A.B.D.; De Rycke, R.; Hoogenboom, R.; De Geest, B.G. Salt-driven deposition of thermoresponsive polymer-coated metal nanoparticles on solid substrates. Angewandte Chemie International Edition 2016, 2016, 55, 7086-7090.
2）Zhang, Z.; Van Steendam, K.; Maji, S.; Balcaen, L.; Anoshkina, Y.; Zhang, Q.; Vanluchene, G.; De Rycke, R.; Van Haecke, F.; Defroce, D.; Hoogenboom, R.; De Geest, B.G. Tailoring cellular uptake of gold nanoparticles via the hydrophillic-to-hydrophobic ratio of their (co)polymer coating. Advanced Functional Materials 2015, 25, 3433-3439.
3）Zhang, Z.; Maji, S.; Antunes, A.B.D.; De Rycke, R.; Zhang, Q.L.; Hoogenboom, R.; De Geest, B.G. Salt Plays a Pivotal Role in the Temperature-Responsive Aggregation and Layer-by-Layer Assembly of Polymer-Decorated Gold Nanoparticles. Chemistry of Materials 2013, 25, 4297-4303.
4）Zhang, Z.; Schepens, B.; Nuhn, L.; Saelens, X.; Schotsaert, M.; Callewaert, N.; De Rycke, R.; Zhang, Q.; Moins, S.; Benali, S.; Mespouille, L.; Hoogenboom, R.; De Geest, B.G. Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination. Chemical Communications 2016, 52, 3352-3355.
5）Zhang, Z.; Vanparijs, N.; Vandewalle, S.; Du Prez, FE.; Nuhn, L.; De Geest, B.G. Squaric ester amides as hydrolysis-resistant functional groups for protein-conjugation of RAFT-derived polymers. Polymer Chemistry 2016, 7, 7242 - 7248
6）Zhang, Z.; Bi, X.; Li, H.; Huang, G. Enhanced targeting efficiency of PLGA microspheres loaded with Lornoxicam for intra-articular administration. Drug Delivery 2011, 18, 536-544.
7）Zhang, Z.; Huang, G. Intra-articular lornoxicam loaded PLGA microspheres: enhanced therapeutic efficiency and decreased systemic toxicity in the treatment of osteoarthritis. Drug Delivery 2012, 19, 255-263.
8）De la Rosa, V.R.; Zhang, Z.; De Geest, B.G.; Hoogenboom R. Colorimetric Logic gates based on novel poly(2-alkyl-2-oxazoline) coated gold nanoparticles. Advanced Functional Materials 2015, 25, 2511-2519.
9）Dierendonck, M.; Fierens, K.; De Rycke, R.; Lybaert, L.; Maji, S.; Zhang, Z.; Zhang, Q.; Hoogenboom, R.; Lambrecht, B.N.; Grooten, J.; Remon, J.P.; De Koker, S.; De Geest, B.G. Nanoporous hydrogen bonded polymeric microparticles: facile and economic production of cross presentation promoting vaccine carriers. Advanced Functional Materials 2014, 24, 4634-4644.
10）Li, H.; Fierens, K.; Zhang, Z.; Vanparijs, N.; Schuijs, M.; Van Steendam, K.; Deiner Garcia, N.; De Rycke, R.; De Beer, T.; De Beuckelaer, A.; De Koker, S.; Deforce, D.; Albertazzi, L.; Grooten, J.; Lambrecht, B.N.; De Geest, B.G. Spontaneous protein adsorption on graphene oxide nanosheets allows efficient intracellular vaccine protein delivery. ACS Applied Materials & Interfaces 2016, 8, 1147-1155.