姓名职称：
谢玮 讲师，硕士生导师
教育经历：
2004/09-2008/07 厦门大学，生命科学学院，本科，生物技术专业。
2008/09-2014/12 厦门大学，生命科学学院，博士，细胞生物学专业，导师：尤涵教授。
工作经历：
2015/03-2016/08 山东大学，药学院，博士后，药学专业，导师：沈月毛教授。
2016/09-至今 山东师范大学，生命科学学院，职位：讲师。
研究兴趣，领域：
研究方向：细胞骨架、细胞连接和相关疾病
开设课程：
本科：细胞生物学实验、癌生物学、干细胞生物学、生物制药技术、生物制剂制备原理与技术
主持或参加科研项目及人才计划项目情况：
1．细胞自噬在 HIV gp120 诱导上皮通透性中的作用及分子机制，国家自然科学青年基金（**），2018/01-2020/12，24万元，主持。
2．Rac1 GTPase的分子激动剂诱导细胞自噬与细胞凋亡的机制研究，山东师范大学培育基金项目，2016.09-2019.09，2万元，主持。
3．MED靶向小分子GTP酶Rac1调控上皮细胞间质转化及转移，山东省博士后创新基金，2015/11-2018/12，10万元，主持。
4．P49/STRAP与MYOCD相互作用协同调控血管平滑肌细胞表型转化的机制，国家自然科学基金面上项目（**），2019/01-2022/12，60万元，第二位。
5．线虫减数分裂cohesion复合体和HORMA蛋白相互作用分子机制的研究，国家自然科学青年基金（**），2018/01-2021/12，25万元，第三位。
代表性论文：
1.Wei Xie, Dengwen Li*, Dan Dong, Yuanyuan Li, You Zhang, Liangwei Duan, Xinqi Liu, Wenxiang Meng, Min Liu, Jun Zhou*, HIV-1 exposure triggers autophagic degradation of stathmin and hyperstabilization of microtubules to disrupt epithelial cell junctions, Signal Transduct Target Ther, 2020, 5: 79.
2.Dan Dong, Wei Xie*, Min Liu*, Alteration of cell junctions during viral infection, Thorac Cancer, 2020, 11: 519-525.
3.Wei Xie, Wei Zhang, Mingwei Sun, Chunhua Lu, Yuemao Shen*, Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis, Appl Microbiol Biotechnol, 2018, 102: 5965-5975.
4.Wei Xie*, Jun Zhou, Aberrant regulation of autophagy in mammalian diseases, Biol Lett, 2018, 14.
5.Wei Xie, Jun Zhou*, Regulation of mitotic spindle orientation during epidermal stratification, J Cell Physiol, 2017, 232: 1634-1639.
6.Wei Xie^#, Yunfan Yang^#, Siqi Gao, Ting Song, Yuhan Wu, Dengwen Li, Min Liu, Jun Zhou*, The tumor suppressor CYLD controls epithelial morphogenesis and homeostasis by regulating mitotic spindle behavior and adherens junction assembly, J Genet Genomics, 2017, 44: 343-353.
7.Wei Xie, Lei Zhang, Haifeng Jiao, Li Guan, Junmin Zha, Xiaotong Li, Mian Wu, Zhanxiang Wang, Jiahuai Han, Han You*, Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA, Autophagy, 2015, 11: 1623-1635.
8.Xianfei He, Yan Zhang, Lihong Yang, Jie Feng, Song Yang, Te Li, Tao Zhong, Qingchao Li, Wei Xie, Min Liu, Jun Zhou, Dengwen Li*, Songbo Xie*, BAG6 is a novel microtubule-binding protein that regulates ciliogenesis by modulating the cell cycle and interacting with gamma-tubulin, Exp Cell Res, 2020, 387: 111776.
9.Songbo Xie*, Yuhan Wu, Huijie Hao, Jingrui Li, Song Guo, Wei Xie, Dengwen Li, Jun Zhou, Jinmin Gao, Min Liu*, CYLD deficiency promotes pancreatic cancer development by causing mitotic defects, J Cell Physiol, 2019, 234: 9723-9732.
10.Miao Chen, Yu Cao, Dan Dong, Zhenhua Zhang, Yijun Zhang, Jie Chen, Youguang Luo, Qiang Chen, Xin Xiao, Jun Zhou, Wei Xie, Dengwen Li, Songbo Xie*, Min Liu*, Regulation of mitotic spindle orientation by phosphorylation of end binding protein 1, Exp Cell Res, 2019, 384: 111618.
11.Lei Zhang, Yang Mei, Naiyang Fu, Li Guan, Wei Xie, Huihui Liu, Chundong Yu, Zhenyu Yin, Victor C Yu, Han You*, TRIM39 regulates cell cycle progression and DNA damage responses via stabilizing p21, Proc Natl Acad Sci U S A, 2012, 109: 20937-20942.
12.Yang Mei, Yiru Zhang, Kazuo Yamamoto, Wei Xie, Tak W Mak*, Han You*, FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation, Proc Natl Acad Sci U S A, 2009, 106: 5153-5158.