删除或更新信息,请邮件至freekaoyan#163.com(#换成@)

山东师范大学化学化工与材料科学院导师教师师资介绍简介-张卫

本站小编 Free考研考试/2020-12-01

基本资料


职称:
教授

专业:
分析化学

博(硕)导:
硕导

最终学历:
博士

联系电话:


电子邮件:
zhangwei@sdnu.edu.cn

简历及研究领域

个人简介:
张卫,山东禹城人,博士,教授,硕士生导师。山东省****基金获得者。2012年毕业于南开大学化学学院分析化学专业获博士学位,同年进入山东师范大学化学化工与材料科学学院工作至今。主要从事仿生荧光传感材料的设计、制备及应用研究。针对复杂样品中目标蛋白质的定量分析问题,开展了一系列高灵敏的荧光检测方法研究,围绕细胞内重要的活性功能分子,发展了系列的荧光成像分析方法,取得了多项创新性和系统性的科研成果。(1)利用分子印迹技术提高了荧光材料对目标蛋白质分子的选择性,发展了蛋白质特异性识别的荧光检测方法,为蛋白组学提供新的研究策略和分析方法。(2)构建了高灵敏、高选择性的荧光分析体系,并用于细胞及活体内活性小分子成像分析。在学术期刊发表论文32篇,SCI他引1329次,其中以第一或通讯作者发表在Angew. Chem. Int. Ed. 2篇, Chem. Sci. 2篇,Chem. Commun. 2篇, Anal. Chem. 2篇,其中单篇他引次数过百的论文3篇。研究结果曾被多家杂志如Chem. Soc. Rev., Angew. Chem. Int. Ed.等正面报道和评述。

代表性论文

近期已发表的主要论文如下:
(1)Wei Zhang, Jun Lu, Xiaonan Gao, Ping Li*, Wen Zhang, Yu Ma, Hui Wang, Bo Tang*. Enhanced Photodynamic Therapy by Reduced Levels of Intracellular Glutathione Obtained By Employing a Nano-MOF with CuII as Active Center. Angew. Chem. Int. Ed., 2018, 57, 4891-4896.
(2) Wei Zhang, Wei Liu, Ping Li*, Haibin Xiao, Hui Wang, and Bo Tang*. A Fluorescence Nanosensor for Glycoproteins with Activity Based on the Molecularly Imprinted Spatial Structure of the Target and Boronate Affinity. Angew. Chem. Int. Ed., 2014, 53, 12489-12493.
(3)Wei Zhang*, Ruixia Wang, Wei Liu, Xin Wang, Ping Li*, Wen Zhang, Hui Wang and Bo Tang*. Te-containing carbon dots for fluorescence imaging of superoxide anion in mice during acute strenuous exercise or emotional changes. Chem. Sci., 2018, 9, 721-727.
(4)Wei Zhang*, Jiheng Xu, Ping Li, Xiaonan Gao, Wen Zhang, Hui Wang and Bo Tang*. Treatment of hyperphosphatemia based on specific interaction between phosphorus and active center Zr(IV) of nano-MOFs. Chem. Sci., 2018, 9, 7483-7487.
(5) Wei Zhang, Junqing Kang, Ping Li*, Lu Liu, Hui Wang and Bo Tang*. Two-photon fluorescence imaging of sialylated glycans in vivo based on a sialic acid imprinted conjugated polymer nanoprobe. Chem. Commun., 2016, 52, 13991-13994.
(6) Wei Zhang, Junqing Kang, Ping Li*, Hui Wang, and Bo Tang*. Dual Signaling Molecule Sensor for Rapid Detection of Hydrogen Sulfide Based on Modified Tetraphenylethylene. Anal. Chem., 2015, 87, 8964-8969.
(7)Wei Zhang, Wei Liu, Ping Li*, Fang Huang, Hui Wang, and Bo Tang*. Rapid-Response Fluorescent Probe for Hydrogen Peroxide in Living Cells Based on Increased Polarity of C-B Bonds. Anal. Chem., 2015, 87, 9825-9828.
(8)Wei Zhang, Wei Liu, Ping Li*, Junqing Kang, Jiaoyang Wang, Hui Wang and Bo Tang*. Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo. Chem. Commun., 2015, 51, 10150-10153.
(9)Wei Zhang, Xi-Wen He, Wen-You Li, Yu-Kui Zhang. Selective capture and fluorescent quantification of glycoproteins by using aminophenylboronic acid functionalized mesoporous silica coating CdTe quantum dots. J. Mater. Chem. B, 2013, 1: 347-352.
(10)Wei Zhang, Xi-Wen He, Yang Chen, Wen-You Li, Yu-Kui Zhang. Molecularly imprinted polymer anchored on the surface of denatured bovine serum albumin modified CdTe quantum dots as fluorescent artificial receptor for recognition of target protein. Biosens. Bioelectron. 2012, 31: 84-89.
(11)Wei Zhang, Xi-Wen He, Wen-You Li, Yu-Kui Zhang. Thermo-sensitive imprinted polymer coating CdTe quantum dots for target protein specific recognition. Chem. Commun., 2012, 48: 1757-1759.
(12)Wei Zhang, Xi-Wen He, Yang Chen, Wen-You Li, Yu-Kui Zhang. Composite of CdTe quantum dots and molecularly imprinted polymer as a sensing material for cytochrome c. Biosens. Bioelectron., 2011, 26: 2553-2558.
(13)Wei Zhang, Lei Qin, Xi-Wen He, Wen-You Li, Yu-Kui Zhang. Novel surface modified molecularly imprinted polymer using acryloyl-β-cyclodextrin and acrylamide as monomers for selective recognition of lysozyme in aqueous solution. J. Chromatogr. A 2009, 1216: 4560-4567.


主持项目:
1.国家自然科学基金面上项目,**,细胞与活体中功能蛋白糖基化与磷酸化位点识别与互作实时原位荧光成像,2019/01-2022/12,66万,在研,主持。
2.山东省属高校优秀青年人才联合基金项目,ZR2015JL008,基于分子印迹技术的新型传感体系的构建及其在糖蛋白识别中的应用研究,2015/07-2016/12,30万元,已结题,主持。
3.国家自然科学基金青年项目,**,用于非胁迫状态细胞中低浓度活性氧自由基检测的聚合物放大型荧光探针的设计与制备,2014/01-2016/12,25万元,已结题,主持。
4. 山东省重点研发计划项目,2017GSF18196,基于抗原决定基印迹技术的新型荧光纳米探针的制备及应用研究,2017/03-2019/03, 10万元,在研,主持。
5.山东省自然科学基金青年项目,ZR2013BQ005,基于硼与糖蛋白特异性作用的分子印迹型荧光探针的制备及其应用研究,2013/10-2016/10,7万元,已结题,主持。




申请专利:
李文友,张卫,何锡文,张玉奎.一种溶菌酶分子印迹-量子点纳米荧光探针的制备方法(国家发明专利申请号CN 2.0)


研究课题

用于非胁迫状态细胞中低浓度活性氧自由基检测的聚合物放大型荧光探针的设计与制备
国家基金委,2014年1月--2016年12月, 在研


荣誉称号

光华奖学金
2011-12-1,南开大学







相关话题/化学化工 材料