姓名杨国栋 学历博士职称教授
所属部门生物化学与分子生物学系
联系方式电话：** E-mail：gdyang@sdau.edu.cn

　
　　
::教师简介::
杨国栋，博士，副教授，硕士生导师。泰山学者学术骨干。 目前承担了本科生《生命科学导论》、《基础生物化学》、《生物化学实验》以及研究生《高级生化实验技术》等课程的教学工作。 近年来，主要承担了****与创新团队发展计划子课题，并参加了国家高技术研究发展计划(863计划)、国家重点基础研究发展计划（973计划）和国家自然科学基金等多项课题。获得了基因发明专利两项。在《Journal of Genetics》、《Acta Physiol. Plant》、《Nucleic Acids Res.》、《Molecular Cell》、《中国科学》等国内外著名学术刊物上发表研究论文近20余篇。

　　
::教学工作::
生物化学与分子生物学国家级教学团队成员。承担本科生《生命科学导论》、《生物化学》、《生物化学实验》；研究生《高级生化实验技术》等课程的教学工作。

　　
::研究方向::
MicroRNA比较基因组学分析；MicroRNA（特别是Intronic MicroRNA）在植物抵御非生物胁迫（如干旱、低温、盐胁迫等），以及植物生长发育过程的作用。

　　
::科研项目::
1. 教育部“****创新团队发展计划”《作物高产优质的生理与分子基础》2007-2009
2. 转基因生物新品种培育重大专项《抗逆和抗除草剂关键基因克隆及功能验证》参加第一位2009-2012
3. 转基因生物新品种培育科技重大专项《棉花抗旱、耐盐和低温重要新基因的克隆和功能验证》参加第二位2009-2011

　　
::学术论文::
1. Yang, G.D., Yan K., Wu B.J, Wang Y.H., Gao Y.X., and Zheng C.C. (2012) Genome-wide analysis of intronic microRNAs in rice and Arabidopsis. Journal of Genetics, In press.

2. Liu, P.,* Yang, G. D.,*(co-first author), Li, H. Zheng, C.C. and Wu, C.A. (2010) Overexpression of NHX1s in transgenic Arabidopsis enhances photoprotection capacity in high salinity and drought conditions. Acta Physiol Plant, 32, 81–90. springerlink

3. Guo, Y.H, Yu, Y.P, Zheng, C.C, Yang, G.D*. (2010) Screening of proteins interacting with GhZFP1 zinc finger protein from cotton by Yeast Two Hybrid System. Chinese Journal of Biochemistry and Molecular Biology, 26(5): 423-428.

4. Wu, B.J, Yan, B.L, Liu, D.L, Zheng, C.C, Yang, G.D*. (2010) Bioinformatical analysis of salinity-responsive promoters in Arabidopsis thaliana. Journal of Shandong Agricultural University (Natural Science), 41(2):164-168.

5. Yan, K., Liu, P., Wu, C.A., Yang, G.D., Xu, R., Guo, Q.H., Huang, J.G., and Zheng C.C. (2012) Stress-induced alternative splicing provides a novel mechanism for the regulation of microRNA processing in Arabidopsis thaliana. Molecular Cell, 2012 Oct 10. PMID: **

6. Li, Y., Wu, B., Yu, Y., Yang, G., Wu, C. and Zheng, C. (2011) Genome-wide analysis of the RING finger gene family in apple. Mol Genet Genomics, 286, 81-94. PMID: **

7. Xi, D.M., Liu, W.S., Yang, G.D., Wu, C.A. and Zheng, C.C. (2010) Seed-specific overexpression of antioxidant genes in Arabidopsis enhances oxidative stress tolerance during germination and early seedling growth. Plant Biotechnol J, 8, 796-806. PMID: **

8. Huang, J.G., Yang, M., Liu, P., Yang, G.D., Wu, C.A. and Zheng, C.C. (2010) Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis. Gene, 451, 38-44.PMID: **

9. Yang, Y.T., Yu, Y.L., Yang, G.D., Zhang, J.D. and Zheng, C.C. (2009) Tissue-specific expression of the PNZIP promoter is mediated by combinatorial interaction of different cis-elements and a novel transcriptional factor. Nucleic Acids Res., 37, 2630-2644. PMID: **

10. Zhang, J., Lu, L., Ji, L., Yang, G. and Zheng, C. (2009) Functional characterization of a tobacco matrix attachment region-mediated enhancement of transgene expression. Transgenic Res, 18, 377-385. PMID: **

11. Huang, J.G., Yang, M., Liu, P., Yang, G.D., Wu, C.A. and Zheng, C.C. (2009) GhDREB1 enhances abiotic stress tolerance, delays GA-mediated development and represses cytokinin signalling in transgenic Arabidopsis. Plant Cell Environ, 32, 1132-1145. PMID: **

12. Wang, D., Guo, Y., Wu, C., Yang, G., Li, Y. and Zheng, C. (2008) Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics, 9, 44. PMID: **

13. Li, H.Y., Yang, G.D., Shu, H.R., Yang, Y.T., Ye, B.X., Nishida, I. and Zheng, C.C. (2006) Colonization by the arbuscular mycorrhizal fungus Glomus versiforme induces a defense response against the root-knot nematode Meloidogyne incognita in the grapevine (Vitis amurensis Rupr.), which includes transcriptional activation of the class III chitinase gene VCH3. Plant Cell Physiol, 47, 154-163. PMID: **

14. Liu N, Yang Y T, Liu H H, Yang G D, Zhang N H, Zheng C C (2004). NTZIP antisense plants show reduced chlorophyll levels. Plant Physiology and Biochemistry, 42(4): 321-327.

15. Wu C A, Yang G D , Meng Q W, Zheng C C (2004), The cotton GhNHX1 gene encoding a novel putative tonoplast Na(+)/H(+) antiporter plays an important role in salt stress. Plant and Cell Physiology, 45(5):600-607.

16. Xue H, Yang Y T , Wu C A, Yang G D , Zhang M M, Zheng C C (2005). TM2, a novel strong matrix attachment region isolated from tobacco, increases transgene expression in transgenic rice calli and plants. Theoretical and Applied Genetics, 110(4): 620-627.

17.郑成超, 杨国栋, 王丹 等 (2002). 一种拟南芥ZIP 蛋白全长cDNA 的克隆及表达. Acta Biochimica Et Biophysica Sinica, 34(1): 109-112.

18.杨予涛, 杨国栋, 刘石娟, 郭兴启, 郑成超 (2003). 一个光合组织特异表达强启动子的分离及功能分析.Science in China (Series C), 33(4): 298-306.

19.张可伟, 王健美, 杨国栋, 郭兴启, 温孚江, 崔德才, 郑成超(2002). 强MAR 的分离及其体内外功能鉴定.科学通报, 47(20): 1572-1577.

　　
::科研成果::
1. 植物microRNA专业数据库：http://www.plantmirgo.org/
2. 棉花Na+/H+反向转运蛋白基因及其应用，专利号：ZL**.1
3. 棉花金属硫蛋白基因GhMT1序列及其克隆与应用，专利号：ZL**1.X