药学院(葡萄酒学院)教师个人情况登记表
张桂龙 |
药理学,教授,硕士生导师 |
联系电话:**519 |
电子邮箱:glzhang@ipp.ac.cn |
个人简介:
张桂龙,男,教授,硕士生导师,2019 年荣获“泰山学者青年专家”称号。主要从事磁共振纳米诊疗剂对肿瘤早期诊断与靶向治疗等研究工作。目前,主持安徽省自然科学基金面上项目 1 项,国家重点研发计划子课题 1项,安徽省省级环保课题 1 项。在 Adv. Funct.Mater., ACS Nano, Biomaterials, Chem.Eng. J., ACS Appl. Mater. Interfaces, Nanoscale 等国际权威期刊发表 SCI 论文 50 余篇。申请专利 16项,其中授权 7 项,成功转化 2 项。
学习经历:
2011 年 9 月至 2016 年 11 月,中国科学技术大学,材料物理与化学专业,博士研究生
2007 年 9 月至 2011 年 7 月,东北林业大学,化学专业,本科
工作经历:
2019 年 6 月至今,滨州医学院,药物化学专业,教授
2016 年 11 月至 2019 年5 月,中国科学院合肥物质科学研究院,生物物理专业,助理研究员
主讲课程:
1、《基因的诊断与治疗》(研究生 选修课)
研究方向:
1.肿瘤微环境响应的新型磁共振纳米造影开关的研究
2.肿瘤微环境响应的诊疗一体化体系的开发
科研项目:
1、主持国家重点研发计划(子课题)--“低毒安全高效药、械与稻麦主要病虫草害绿色高效防控技术集成”(No.2018YFD**-4,2018.7-2020.7)
2、主持安徽省自然科学基金面上项目--“钆掺杂氧化铁纳米簇提高宫颈癌磁共振造影和治疗效果的机理研究” (No.**MB38,2018.7-2021.6)
3、主持安徽省省级环保项目--“安徽省污染耕地安全利用技术研究与示范”
(No.2017-04,2017.10-2019.9)
4 、 主 持 企 业 委 托 研 发 项目 -- “ 靶 向 药 物 载 体 与 新 型 造 影 剂 ”
(No.****,2018.5.1-2020.4.30)
代表性论文及专利:
1.
Zhou, Jian; Qian, Junchao; Zhong, Kai; Zheng, Kang; Kaigler, Darnell;Liu, Wenqing; Zhang, Xin; Zou, Duohong; Wu, Zhengyan. Gadolinium-Doped IronOxide Nanoprobe as Multifunctional Bioimaging Agent and Drug Delivery System.
2.
Cai, Dongqing; Zhang, Xin; Wu, Zhengyan.Hydroxylated Mesoporous Nanosilica Coated by Polyethylenimine Coupled with Gadolinium andFolic Acid: A Tumor-Targeted T1 Magnetic Resonance Contrast Agent and DrugDelivery System. ACS Applied Materials& Interfaces 2015, 7,14192-14200. (IF:8.456,中科院一区)
3.
Cheng, Zhiliang; Wu, Zhengyan. Magnetic RelaxationSwitch Detecting Boric Acid or Borate Ester through One-Pot SynthesizedPoly(vinylalcohol) Functionalized Nanomagnetic Iron Oxide. ACS Applied Materials & Interfaces 2015, 7, 16837-16841. (IF: 8.456,中科院一区)
4.
Wu, Zhengyan. Composite of Functional MesoporousSilica and DNA: An Enzyme-Responsive Controlled Release Drug Carrier System.
5.
Dongqing; He, Jiacai; Wu, Yiqun; Huang, Wei;Wang, Yuanyin; Zhang, Xin; Zhong, Kai; Zou, Duohong; Wu, Zhengyan. A tailorednanosheet decorated with a metallized dendrimer for angiography and magneticresonance imaging-guided combined chemotherapy. Nanoscale, 2018,
10, 488-498. (IF:6.970,中科院一区)
6.
nanosystem for controlling seleniumfertilizer release and improving selenium utilization efficiency in vegetables.Carbon, 2018, 129, 711-719. (IF:7.466,中科院一区)
7.
Junfeng; Zhong, Kai; Zhang,Xin; Wu, Zhengyan. A Multifunctional Magnetic Composite Material as a DrugDelivery System and a Magnetic Resonance Contrast Agent. Particle & Particle Systems Characterization 2014, 31,976-984.(IF: 4.194,中科院二区)
8.
Microstructural Modification of Diatomite by Acid Treatment,High-speed Shear, and Ultrasound.
Microporous and Mesoporous Materials
9. Xiao, Jianmin﹟; Zhang, Guilong﹟; Xu, Rui; Chen, Hui; Wang, Huijuan;Tian, Geng;
Wang, Bin; Zhang, Zhiyuan;Yang, Hongyi; Zhong, Kai; Zou, Duohong; Wu, Zhengyan. A pH-responsive platformcombining chemodynamic therapy with limotherapy for simultaneous
bioimaging andsynergistic cancer therapy. Biomaterials,
中科院一区)
10. Sun, Xiao﹟; Zhang,
Bai, Guo;Yang, Chi;Zhang, Zhiyuan;Zhang, Xin;Zou, Duohong;Wu, Zhengyan.A biodegradable MnSiO3@Fe3O4 nanoplatformfor dual-mode magneticresonance imaging guided
combinatorial cancer therapy. Biomaterials, 2019, 194, 151-160(. IF:10.273,中科院一区)
11. Dan Wang﹟, Haiyan Lin﹟,
Theranostic Platform for Synchronous Magnetic Resonance Imaging Diagnosis and
Chemotherapy.ACS Applied Materials & Interfaces,
12. Xiao, Jianmin﹟; Zhang, Guilong
Dongqing; Wu,Zhengyan. Fabricating High-Performance T2-Weighted Contrast Agents via AdjustingComposition andSize of NanomagneticIronOxide. ACS Applied Materials &
Interfaces,
13. Si, Yuanchun
water interaction to increase the dual-mode MR contrast performance of gadolinium-doped iron
oxidenanoclusters. Chemical EngineeringJournal, 2019,
14. Xiang,Yubin
Attapulgite-BasedHydrogel.
(IF:6.970,中科院二区)
15. Sun, Xiao
16. Sun, Xiao; Cai, Chuanjie;Wang, Qian; Cai, Dongqing; Qian, Junchao; Chi, Yu; Zheng, Kang;
Zhang,Xin; Zhang, Guilong*
porous/hollownanoworm as a drug delivery system and a bioimaging agent. Physical Chemistry Chemical Physics, 2016, 18, 7820-7828. (IF:3.567,中科院二区)
荣誉获奖:
1.荣获中国科学技术大学优秀博士论文(2017 年)
2.荣获中国科学院院长优秀奖(2016 年)
3.荣获中国科学元保罗生物科技冠名奖(2014 年)
社会兼职:
1. 中国生物材料学会会员