薛华明 副主任医师，副教授
硕士招生类型：学术型；专业型
硕士招生专业：外科学（骨科）
博士招生类型：学术型；专业型
博士招生专业：外科学（骨科）
所在院系：附属杨浦医院
联系方式：x11h22m33@126.com
课题组链接：
研究方向
主要任职
科研业绩

骨关节炎软骨退变的机理及修复
Mechanismand repair of cartilage degeneration in osteoarthritis




上海市中西医结合学会关节学组委员
Memberof Joint Group of Shanghai Association of Integrative Medicine
上海市中西医结合学会创伤学组委员
Memberof Trauma Group of Shanghai Association of Integrative Medicine
上海市康复医学会骨科康复专业委员会委员
Memberof Orthopaedic Rehabilitation Department, Shanghai Rehabilitation MedicalAssociation
《生物医学工程与临床》杂志特约编委
SpecialEditor of the Journal of Biomedical Engineering and Clinic
《生物骨科材料与临床研究》特约审稿人
SpecialReviewer for the journal of Biomaterials and Clinical Research
《中国组织工程研究》审稿人
Reviewerof China Tissue Engineering Research
上海市科技奖励评审专家
ShanghaiScience and Technology Awards Evaluation Expert




①近年来以第一作者或通讯作者发表的文章：
[1] YihuiTu, Huaming Xue*,Minwei Cai,et al. Improvement of femoral component sizeprediction using a C-arm intensifier guide and our established algorithm inunicompartmental knee arthroplasty: a report from a Chinese population.Knee,2014 ,21(2):435-438. 通讯作者, SCI
[2] HuamingXue*, Yihui Tu, Minwei Cai, Anli Yang. Locking Compression Plate and CerclageBand for Type B1 Periprosthetic Femoral Fractures: Preliminary Results atAverage 30-Month Follow-Up. J Arthroplasty, 26(3): 467-471.e1, 2011. SCI
[3] YihuiTu, Huaming Xue,Wendy Francis,et al.Lactoferrin inhibits dexamethasone-inducedchondrocyte impairment from osteoarthritic cartilage through up-regulation ofextracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, andCaspase 3.Biochemical and Biophysical Research Communications, 2013,441(1): 249–255. SCI，共一
[4] HuamingXue, Yihui Tu*, Minwei Cai. Comparison of Unilateral Versus BilateralInstrumented Transforaminal Lumbar Interbody Fusion in Degenerative LumbarDiseases. The Spine Journal,2012,12(3):209-215. SCI
[5] XueHM, Tu YH, Ma T, Liu XD, Wen T, Cai MW, Xia ZD, Mei J. Lactoferrin InhibitsIL-1β-Induced Chondrocyte Apoptosis Through AKT1-Induced CREB1 Activation. CellPhysiol Biochem. 2015;36(6):2456-65.
②科研课题：
Scientificresearch topics:
2014－2016 国家自然青年科学基金：乳铁蛋白调控PI3K/Akt信号通路抑制骨关节炎软骨细胞凋亡的机制研究，项目编号：**
2014－2016 National Natural Science Foundation ofChina: The mechanism of lactoferrin regulating PI3K/Akt signaling pathway toinhibit chondrocyte apoptosis in osteoarthritis, Project number: **
2011－2013 上海卫生局局级青年课题：单边椎弓根螺钉固定治疗单或双节段腰椎间盘退变的生物力学和前瞻性研究，项目编号：**
ShanghaiHealth Bureau Youth Project: Biomechanical and prospective study of unilateralpedicle screw fixation for single or double-segment lumbar disc degeneration,item number: **
2007－2010 上海市杨浦区卫计委青年课题：单侧TLIF治疗腰椎间盘退变的前瞻性临床研究，项目编号：Y**
ShanghaiYangpu District Health bureau Youth Project: Prospective clinical study ofunilateral TLIF in the treatment of lumbar disc degeneration, item number:Y**
④ 参编论著
Edited books
(1) 杨安礼，刘亮，……，薛华明. 椎间盘突出症的微创技术.ISBN:7-80703-577-3，上海:百家出版社, 270千字，2006.11.
As a participantin the compilation of “Minimally invasive technique for disc herniation” ,ISBN:7-80703-577-3，2006.11. (in chinese)
(2)马原，刘少喻，曾昭池，……，薛华明.脊柱外科内固定技术，ISBN:978-7-5091-3332-3, 北京?人民军医出版社，488千字，2010.
As a participant in the compilation of ”Surgical FixationTechniques in Spine Surgery”, ISBN: 978-7-5091-3332-3, p.6666 (2009). (inchinese)
⑤ 专利
2011.10，组合式神经拉钩（国家实用新型），专利号：0.8，第1
Patent
2011.10, Combined nerve pull hook (NationalUtility Model), patent number: 0.8, 1^st author