王丽新 主任医师，讲师
硕士招生类型：学术型
硕士招生专业：中医学
博士招生类型：无
博士招生专业：无
所在院系：附属肺科医院
联系方式：wlx1126@hotmail.com
课题组链接：
研究方向
主要任职
科研业绩

中医药防治肺癌及呼吸系统疾病Prevention and treatment of lung cancer and respiratory diseases with traditional Chinese medicine
同济大学附属上海市肺科医院中西结合科主任，主任医师，硕士生导师。美国西奈山医学院Mount Sinai Medical Centre访问****。
上海市传统医学工程协会肿瘤分会副主任委员，世界中医药学会肿瘤精准医学委员会常务理事，中国医师协会中西医结合分会呼吸专业委员会常务理事，世界中医药学会热病专业委员会常务理事，中国医药教育协会呼吸病康复委员会理事，中国医促会结核专科分会中医学组副组长，CSCO中西医结合肿瘤专业委员会理事。
国家自然科学基金网评评审专家，上海市科委评审专家，《微生物与感染杂志》审稿专家，Oncology Reports审稿专家，《上海中医药大学学报》审稿专家。
Director, chief physician and master's tutor of department of integrated Chinese and western medicine, Shanghai Lung Hospital affiliated to Tongji University.Visiting Scholar of Mount Sinai Medical Center, Mount Sinai Medical College,USA.
Vice-chairman of Tumor Branch of Shanghai Traditional Medical Engineering Association,standing director of the Cancer Precision Medical Committee of the World Society of Traditional Chinese Medicine,expert members of the Respiratory Committee of the Branch of Integrated Traditional Chinese and Western Medicine, Chinese Medical Association,standing director of the Fever Professional Committee of the World Society of Traditional Chinese Medicine,member of Respiratory Rehabilitation Committee of China Medical Education Association,vice-chairman of Traditional Chinese Medicine Group, TB Branch of China Association for International Exchange and Promotion of Medical Care,Member of CSCO Professional Committee on Oncology of Integrative Traditional Chinese and Western Medicine.
Assessment Expert of National Natural Science Foundation of China,Evaluation experts of Shanghai Science and Technology Commission,review expert of Journal of Microbiology and Infection,review expert of Oncology Reports, review expert of Journal of Shanghai University of Traditional Chinese Medicine
主要研究论文20余篇，参编著作2部，近五年来先后主持国家自然科学基金、上海市科委创新引导项目、上海市申康中心临床创新项目、上海市教委、上海市卫生局等多项课题研究。先后受上海中医药大学后备业务专家、上海市白玉兰人才项目资助。
科研课题：
1.国家自然科学基金项目：基于IL33/ST通路探讨温肾方调控哮喘免疫失衡的机理研究（2015－2019，第一负责人）
2.上海市中医药管理局重点专科培育项目（2019-2021，第一负责人）
3.上海市科委引导类科技支撑项目（**）：补肾益髓方-督灸联合化疗治疗治疗晚期非小细胞肺癌的临床疗效观察及规范化研究 (2018-2021，第一负责人)
4.上海市申康中心临床科技创新项目：益气解毒通络方联合EGFR-TKI延缓晚期非小细胞肺癌靶向耐药的研究及临床疗效评价（SHDC12018X20）(2018.11-2021.11,第一负责人)
5.上海市三年行动计划优势病种培育：基于肺络理论治疗肺间质纤维化（2019-2020，第一负责人）
6.上海市科委引导类科技支撑项目（**）：非结核分枝杆菌患者的中西医结合治疗策略及规范化研究（2019－2022，主要研究者）
7.上海市科委科研基金：基于肺络理论同病异治肺间质纤维化的临床疗效评价和规范化研究 （2015－2018，第一负责人）
8.上海市卫生局：温阳补肾方对哮喘小鼠骨髓树突细胞TLR信号的调节作用（2014－2016， 第一负责人）
9.原发性支气管肺癌中医专病联盟（分中心负责人）（2018-2021）
10.常见恶性肿瘤中医临床研究 上海市三年行动计划（主要研究者）（2018-2021）
研究论文：
1.Jia yong Liu*, Chaoqian Zhao*, Bin Liu*, Hua Liu# and Lixin Wang#, Analgesia and curative effect of pamidronate disodium combined with chemotherapy on elderly patients with advanced metastatic bone cancer, Oncology Letters, 2019, 18: 771-775
2.Fang Hu, Changhui Li, Jianlin Xu, Jindong Guo, Yinchen Shen, Wei Nie, Xiaoxuan Zheng, Lixin Wang, Hai Zhang, Baohui Han? , Xueyan Zhang?, Additional local consolidative therapy has survival benefit over EGFR tyrosine kinase inhibitors alone in bone oligometastatic lung adenocarcinoma patients, Lung Cancer 135 (2019) 138–144
3.Zhiyi dong, Lixin Wang*, HDAC1 is indirectly involved in the epigenetic regulation of p38 MAPK that drive the lung cancer progression. European Review for Medical and Pharmacological Sciences.2018(10)
4.LiXin Wang, Zhong-Hua Wu, Gui-Fang Wang, Guo-Hua Wang, Yu Guan, Fei-Qiao Peng, Ying Song, Ying Song, Wei Xu. Facile synthesis and biologicalassessment of conjugated linolenic acid-modified, bovine serum albumin-linked,magnetic gamma-Fe2O3 nano-composites. Chemical Engineering Journal, 2015.,259(1): 562~573.
5.Ying Song, Lixin Wang, Changda Liu, Lauren Lisann, David Weir, Ching-feng Huang, Paula J. Busse, FAAAAI, Xiu-Min Li. Sophora Flavescens Alkaloid-Rich Fraction Induction of IL-10 Production and Prevention of Dexamethasone Suppression of Asthma Patient PBMC IL-10 Production Is Associated with Altered DNA Methylation at foxp3 Gene Promoter. Journal of Allergy and Clinical Immunology, 2015, 136(2): AB73~AB73.
6.Song Y, Wang J, Leung N, LiXin Wang, Lisann L, Sicherer SH, Scurlock AM, Pesek R, Perry TT, Jones SM, Li XM. Correlations between basophil activation, allergen specific IgE with outcome and severity of oral food challenges. The Annals of Allergy Asthma & Immunology, 2015, 114(4): 319~326.
7.Liu C, Yang N, Song Y, Lixin Wang, Zi J, Zhang S, Dunkin D, Busse P, Weir D, Tversky J, Miller RL, Goldfarb J, Zhan J, Li XM. Ganoderic acid C-1 isolated from the anti-asthma formula, ASHMI (TM) suppresses TNF-alpha production by mouse macrophages and peripheral blood mononuclear cells from asthma patients. International Immunopharmacology, 2015, 27(2): 224~231.
8.Leung N, Song Y, Wang J, LiXin Wang, Ross J, Sicherer H.S, Straw J, Jones SM, Sampson H, Li XM. Basophil Reactivity and Allergen Specific-IgE Levels but Not Total IgE, Skin Prick Test Size, or Specific IgG4 Are Correlated with Severity of Double-Blind, Placebo-Controlled Food Challenge Reactions. Journal of Allergy and Clinical Immunology, 2013, 131(2): AB84~AB84.
9. Ying Song, Lixin Wang, Changda Liu, Lauren Lisann, David Weir, Ching-feng Huang, Paula J. Busse, FAAAAI, Xiu-Min Li. Sophora Flavescens Alkaloid-Rich Fraction Induction of IL-10 Production and Prevention of Dexamethasone Suppression of Asthma Patient PBMC IL-10 Production Is Associated with Altered DNA Methylation at foxp3 Gene Promoter. Journal of Allergy and Clinical Immunology, 2015, 136(2): AB73~AB73.
10.黄伟玲,宋英,王丽新. 温肾方对哮喘小鼠ILC2相关分子表达的影响[J]. 上海中医药杂志,2019,03:72-76.
11.黄伟玲,王丽新. 温阳补肾法防治支气管哮喘的现代机理研究[J]. 江西中医药,2019,03:64-68.
12.董志毅，王丽新*，中国版EQ-5D效用值评价体系对局部晚期及晚期肺癌患者生活质量评估的价值[J].同济大学学报（医学版）,2018,39(5):83-87.
13.杨清清,黄伟玲,董志毅,鞠立霞,张素芳,屠洪斌,苏晋梅,李岚,韩明权,王丽新.温阳补肾方对哮喘小鼠骨髓树突细胞TLR信号的调节作用[J].上海中医药杂志,2017,50(11):84-90.
14.倪烨,王丽新.加味小青龙汤治疗慢性阻塞性肺疾病急性发作97例[J].河南中医,2017,37(7):1171-1174.
15.倪烨，王丽新，加味小青龙汤治疗慢性阻塞性肺病急性发作机理探讨,亚太传统医药,2016年12卷19期,136-138页
16.余喆,姜国君,张莹,王丽新,倪伟. “邵氏阳虚哮喘贴”治疗重度COPD稳定期(肾阳虚证)患者96例[J]. 江西中医药大学学报,2019,02:27-29.
17.程雪,王丽新,孙鼎,方泓,吴银根. 基于中医传承辅助系统挖掘吴银根治疗特发性肺纤维化的用药规律[J]. 中国中医基础医学杂志,2018,11:1562-1564
18.王丽新，吴银根运用温阳补肾法治疗支气管哮喘经验，上海中医药杂志，第48卷，第12期，1-2页，2014
19.王丽新，赵霞，宋英，温阳补肾方对哮喘小鼠脾脏树突细胞的免疫调控机制研究，上海中医药杂志，第47卷，第7期，83-86页，2014
20.王丽新，彭飞乔，黄海燕，程亚男，张天嵩，肺纤煎治疗肺间质纤维化临床观察,上海中医药大学学报, 第28卷，第3期，47-49页，2014
1.《选对膏方，调好身体》人民卫生出版社 2018 参编
2.《温病汤证新解》 上海科学技术出版社 2018 参编
3. Lipidomics in heath & Disease（Methods & Application），Translational Bioinformatics 2018参编
Director Wang Lixin have more than 20 main research papers and participate in editing 2 works. In the past five years, director Wang has presided over a number of research projects, including the National Natural Science Foundation, the Shanghai Municipal Science and Technology Commission Innovation Guidance Project, the Shanghai Shen Kang Center Clinical Innovation Project, the Shanghai Municipal Education Commission, the Shanghai Municipal Health Bureau, etc. Director Wang has been successively supported by reserve business experts of Shanghai University of Traditional Chinese Medicine and Shanghai Magnolia Talent Project.
1、National Natural Science Foundation Project:Study on the mechanism of Wenshen Decoction regulating immune imbalance in asthma based on IL33/ST pathway.(2015-2019, the first person in charge)
2、Key Specialized Training Program of Shanghai Administration of Traditional Chinese Medicine.(2019-2021, the first person in charge)
3、Shanghai Science and Technology Commission Guidance Science and Technology Support Project (**): Clinical Observation and Standardization Study of Bushen Yisui Prescription-Du Moxibustion Combined with Chemotherapy in the Treatment of Advanced Non-small Cell Lung Cancer.(2018-2021, the first person in charge)
4、Shanghai Shenkang Center Clinical Science and Technology Innovation Project:Research and clinical efficacy evaluation of Yiqi Jiedu Tongluo Decoction combined with EGFR-TKI to delay targeting drug resistance of advanced non-small cell lung cancer (SHDC12018X20).(2018.11-2021.11, the first person in charge)
5、Cultivation of Advantage Diseases in Shanghai Three-year Action Plan: Treatment of Pulmonary Interstitial Fibrosis Based on Lung collateral Theory.(2019-2020, the first person in charge)
6、Guidance Science and Technology Support Project of Shanghai Science and Technology Commission (**): Research on Integrated Traditional Chinese and Western Medicine Therapy Strategy and Standardization for Non-tuberculosis Mycobacterium Patients.(2019-2022, Main Researcher)
7、Scientific Research Foundation of Shanghai Science and Technology Commission: Evaluation and standardization of clinical efficacy of pulmonary interstitial fibrosis based on lung collateral theory in the same disease.(2015-2018, the first person in charge)
8、Shanghai Municipal Health Bureau: Regulating effect of Wenyang Bushen Recipe on TLR signal of bone marrow dendritic cells in asthmatic mice.(2014-2016, the first person in charge)
9、Primary Bronchogenic Lung Cancer Alliance of Traditional Chinese Medicine.(Head of Branch Center) (2018-2021)
10、Clinical Study of Common Malignant Tumors in Traditional Chinese Medicine Shanghai Three-year Action Plan.(Main Researcher) (2018-2021)
1、Weiling Huang,Ying Song, Lixin Wang.Effect of Wenshen Recipe on the Expression of IL C2-related Molecules in Asthma Mice[J].Shanghai Journal of Traditional Chinese Medicine, 2019,03:72-76.
2、Weiling Huang,Lixin Wang.Study on the Modern Mechanism of Warming Yang and Kidney-tonifying Therapy in the Prevention and Treatment of Bronchial Asthma [J].Jiangxi Traditional Chinese Medicine, 2019,03:64-68
3、Zhiyi Dong,Lixin Wang*.Value of EQ-5D utility value evaluation system in evaluating the quality of life of patients with locally advanced and advanced lung cancer [J].Journal of Tongji University (Medical Edition), 2018,39(5): 83-87.
4、Qingqing Yang, Weiling Huang,Zhiyi Dong,Lixia Ju,Sufang Zhang ,Hongbin Tu,Jinmei Su,Lan Li,Mingquan Han,Lixin Wang.Regulation of Wenyang Bushen Recipe on TLR Signal of Bone Marrow Dendritic Cells in Asthmatic Mice[J].Shanghai Journal of Traditional Chinese Medicine, 2017,50(11): 84-90.
5、Ye Ni,Lixin Wang.97 Cases of Acute Attack of Chronic Obstructive Pulmonary Disease Treated with Jiawei Xiaoqinglong Decoction[J].Henan Traditional Chinese Medicine, 2017,37(7): 1171-1174
6、Ye Ni,Lixin Wang.Mechanism of Jiawei Xiaoqinglong Decoction in Treating Acute Attack of Chronic Obstructive Pulmonary Disease, Asia-Pacific Traditional Medicine, Volume 12, No. 19, 2016, PP. 136-138.
7、Zhe Yu,Guojun Jiang,Ying Zhang,Lixin Wang,Wei Ni. "Shao