张扬 副研究员-高研院
硕士招生类型：学术型
硕士招生专业：药学
博士招生类型：无
博士招生专业：无
所在院系：附属第十人民医院
联系方式：zy_benjamin@163
课题组链接：
研究方向
主要任职
科研业绩

学术方面从事递送核酸药物、化疗药物载体、人体骨骼、肠道微生态的纳米材料科学研究。
Major in siRNA gene delivery, chemical medicine vector, orthopaedics and tranmstology, gut microbiota and nanotechnology.
同济大学研究生导师，副教授Associate professor of Tongji University
同济大学附属第十人民医院骨肿瘤研究所、肠道微生态研究所，副研究员
Associate researcher of Bone Tumor Institute and Intestinal microbiota Institute ,Tenth People’s Hospital of Tongji University
同济大学附属第十人民医院科研处副处长Deputy director of the Research Office, Tenth People’s Hospital of Tongji University
浙江省台州中心医院（三甲）科研处处长Chief director of the Research Office, Taizhou Central Hospital, Zhejiang Province
上海张江医学创新研究院，副研究员Associate researcher of Shanghai Zhangjiang Institute of Medical Innovation
上海市医学会肠内肠外营养专科分会青年委员Young alumni council of Shanghai Medical Association Parenteral and Enteral Nutrition Branch
2011年度国家教育部先进工作者，2015年度上海市长宁区创新个人，2016年度上海市长宁区卫生系统十大****，上海市科技进步一等奖，上海市医学科技奖三等奖主要完成人。迄今为止已经申请国家发明专利6项，在国际顶级纳米杂志Biomaterials, In J Pharm，NBM等发表论文20篇，总计影响因子为70余分，先后主持国家自然科学基金、上海市科委基础重大项目子课题（180万）、上海市科委自然科学基金面上项目、上海交大医工交叉面上项目，浙江省自然科学基金，浙江省卫生系统优秀青年基金等多项科研项目。
Professor Zhang has achieved National Ministry of Education Advanced Worker in 2011, Shanghai Changning District Innovative Individual in 2015, Shanghai Changning District Health System Top Ten Outstanding Youth , Shanghai Science and Technology Progress First Prize, Shanghai Medical Science and Technology Award Third Prize Main Finisher in 2016. So far, he has applied for 6 national invention patents, and published 20 papers in the top international nano magazines such as Biomaterials, In J Pharm, NBM, etc., with a total impact factor of more than 70 points. He has hosted the National Natural Science Foundation of China and the Shanghai Municipal Science and Technology Commission (1.8 million), the general project of the Natural Science Foundation of Shanghai Municipal Science and Technology Commission, the general project of Shanghai Jiaotong University, the natural science foundation of Zhejiang Province, the outstanding youth fund of Zhejiang health system and many other scientific research projects.
发表文章：
1.Gao J, Sun J, Li H, Liu W, Zhang Y, Li B, Qian W, Wang H, Chen J, Guo Y. Lyophilized HER2-specific PEGylated immunoliposomes for active siRNA gene silencing. Biomaterials.2010,31:2655-2664.IF2018:10.273.
2.Zhang Y, Li H, Sun J, Gao J, Liu W, Li B, Guo Y, Chen J. DC-Chol/DOPE cationic liposomes: A comparative study of the influence factors on plasmid pDNA and siRNA gene delivery. INTERNATIONAL JOURNAL OF PHARMACEUTICS.2010,390:198-207.IF2018:4.213.
3.Xinxin Zhang, Chi Zhang, Wei Xu, Biao Zhong, Feng Lin, Jian Zhang, Quanxiang Wang, Jiajin Ji, Jie Wei, Yang Zhang. Biodegradable Mesoporous Magnesium Calcium Silicate-Polybutylene Succinate Scaffolds for Osseous Tissue Engineering. International Journal of Nanomedicine.2015,10:6699–6708.IF2014:4.383.
4.ZhangChi, ZhangYang, ZhongBiao, LuoCong-feng. SMAD7 prevents heterotopic ossification in a rat Achilles tendon injury model via regulation of endothelial-mesenchymal transition. The FEBS JOURNAL.2016,283(7):1275-1285.IF2015:4.001.
5.Zhenliang Sun *,Yang Zhang *, Duo Cao *, Xufeng Wang, Xuebing Yan, Hao Li, Linsheng Huang, XiaoQu, Cheng Kong, Huanglong Qin, Man Wang, Wei Xu and Lin Liang.PD-1/PD-L1 pathway and angiogenesis dual recognizable nanoparticles for enhancing chemotherapy of malignant cancer. DRUG DELIVERY.2018,25(1):1746-1755.IF2018：3.829.
6.Tao, SC (Tao, Shi-Cong) ; Rui, BY (Rui, Bi-Yu) ; Wang, QY (Wang, Qi-Yang) ; Zhou, D (Zhou, Ding) ; Zhang, Y (Zhang, Yang) ; Guo, SC (Guo, Shang-Chun)Extracellular vesicle-mimetic nanovesicles transport lncRNA-H19 as competing endogenous RNA for the treatment of diabetic wounds.DRUG DELIVERY.2018,25 (1):241-255.IF2016:6.402.
7.Wu, C (Wu, Chan)* ; Zhang, Y (Zhang, Yang)* ; Yang, DQ (Yang, Daoqiu)* ; Zhang, JF (Zhang, Jinfeng) ; Ma, JJ (Ma, Juanjuan) ; Cheng, D (Cheng, Dan) ; Chen, JM (Chen, Jianming) ; Deng, L (Deng, Li).Novel SN38 derivative-based liposome as anticancer prodrug: an in vitro and in vivo study. International Journal of Nanomedicine.2019,14:75-85.IF2018:4.471.
8.Chi Zhang,Peichun Hsu,Dimin Wang,Wei Zhang,Changqing,Zhang, Shang Guo, Weichao Yang, Xiaokang Wei, Yang Zhang,Biao Zhong.Superparamagnetic iron oxide (SPIO) nanoparticles labeled endothelial progenitor cells (EPCs) administration inhibited heterotopic ossification in rats. Nanomedicine-Nanotechnology Biology and Medicine.online. DOI: https://doi.org/10.1016/j.nano.2019.102078.IF2018：
9.Xiaoqian Feng, Wei Xu, Chi Zhang, Shuo Tan, Jian Zhang, Peng Zhang, Yang Zhang., Facile synthesis of yolk-shell structured Fe3O4@C-Au nanoparticles for thermotherapic application, Materials Letters., accepted.2019/10/
IF2018：12.
10.Ying Wang, Shukui Zhou, Ranxing Yang, Mahbubur Rahman, Russel Clive Sequeira, Nailong Cao, Yang Zhang, Weixin Zhao, Qiang Fu.Magnetic targeting of super-paramagnetic iron oxide nanoparticle labeled myogenic-induced adipose-derived stem cells in a rat model of stress urinary incontinence. Nanomedicine-Nanotechnology Biology and Medicine.30(2020)102281. IF2018：5.57