田海滨 副教授
硕士招生类型：学术型
硕士招生专业：基础医学
博士招生类型：无
博士招生专业：无
所在院系：医学院
联系方式：tianhb@tongji.edu.cn
课题组链接：
研究方向
主要任职
科研业绩

干细胞分化及调控机制研究
“中华细胞与干细胞杂志”编委；
“中国整形美容协会干细胞研究与应用分会”常务理事；
海峡两岸医药卫生交流协会眼科专委会眼干细胞学组秘书；
国家自然科学基金项目评审专家。
2011年底在美国路易斯安那州立大学健康科学中心完成博士后研究，受聘同济大学医学院任副教授。
从事干细胞分化及其在视网膜疾病和糖尿病皮肤疾病治疗作用的研究。
承担项目：
1.国家自然科学基金面上项目（**）：关键转录因子诱导间充质干细胞分化为视网膜色素上皮细胞的机制及功能研究（2018/1-2021/12），主持；
2.国家自然科学基金面上项目（**）：PUFA衍生物调节巨噬细胞极化状态促进糖尿病感染性溃疡创面修复的作用及机制研究（2014/1-2017/12），主持；
3.国家重大科学研究计划（2015CB964601）：眼上皮成体干细胞原位再生治疗重要致盲眼病的机理研究（2015/1-2019/12）,骨干；
4.国家重大科学研究计划（2013CB967501）：干细胞治疗视网膜变性的基础与临床转化研究（2013/1-2017/12）,骨干。
发表文章：
1.Tian H, Xu JY, Tian Y, Cao Y, Lian C, Ou Q, Wu B, Jin C, Gao F, Wang J, Zhang J, Zhang J, Li W, Lu L, Xu GT. A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells. Exp Eye Res. 2018, 177:160-172；
2.Chen S, Li R, Cheng C, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Wang H, Lu L, Xu GT, Tian H. Pseudomonas aeruginosa infection alters the macrophage phenotype switching process during wound healing in diabetic mice. Cell Biol Int. 2018, 42(7):877-889；
3.Wang L, Li P, Tian Y, Li Z, Lian C, Ou Q, Jin C, Gao F, Xu JY, Wang J, Wang F, Zhang J, Zhang J, Li W, Tian H*, Lu L*, Xu GT*. Human umbilical cord mesenchymal stem cells: subpopulations and their difference in cell biology and effects on retinal degeneration in RCS rats. Curr Mol Med. 2017;17(6):421-435；
4.Li P, Tian H, Li Z, Wang L, Gao F, Ou Q, Lian C, Li W, Jin C, Zhang J, Xu JY, Wang J, Zhang J, Wang F, Lu L, Xu GT. Subpopulations of Bone Marrow Mesenchymal Stem Cells Exhibit Differential Effects in Delaying Retinal Degeneration. Curr Mol Med. 2016;16(6):567-81；
5.Li Z, Wang J, Gao F, Zhang J, Tian H, Shi X, Lian C, Sun Y, Li W, Xu JY, Li P, Zhang J, Gao Z, Xu J, Wang F, Lu L, Xu GT. Human Adipose-Derived Stem Cells Delay Retinal Degeneration in Royal College of Surgeons Rats Through Anti-Apoptotic and VEGF-Mediated Neuroprotective Effects. Curr Mol Med. 2016;16(6):553-66；
6.Hong S*, Tian H*, Lu Y, Laborde JM, Muhale FA, Wang Q, Alapure BV, Serhan CN, Bazan NG. Neuroprotectin/protectin D1: endogenous biosynthesis and actions on diabetic macrophages in promoting wound healing and innervation impaired by diabetes. Am J Physiol Cell Physiol. 2014 Dec 1;307(11):C1058-67；
7.Gu L, Xu H, Wang F, Xu G, Sinha D, Wang J, Xu JY, Tian H, Gao F, Li W, Lu L, Zhang J, Xu GT. Erythropoietin Exerts a Neuroprotective Function Against Glutamate Neurotoxicity in Experimental Diabetic Retina. Invest Ophthalmol Vis Sci. 2014, 55(12):8208-8222；
8.Guan Y, Cui L, Qu Z, Lu L, Wang F, Wu Y, Zhang J, Gao F, Tian H, Xu L, Xu G, Li W, Jin Y, Xu GT. Subretinal transplantation of rat MSCs and erythropoietin gene modified rat MSCs for protecting and rescuing degenerative retina in rats. Curr Mol Med. 2013, 13(9):1419-31；
9.Tian H, Lu Y, Shah SP, Wang Q, Hong S. 14S,21R-dihydroxy-docosahexaenoic Acid Treatment Enhances Mesenchymal Stem Cell Amelioration of Renal Ischemia/Reperfusion Injury. Stem Cells Dev. 2012，21(7):1187-99；
10.Tian H, Lu Y, Shah SP, Hong S. Autacoid 14S,21R-dihydroxy-docosahexaenoic acid counteracts diabetic impairment on macrophage pro-healing functions. Am J Pathol. 2011, 179(4):1780-91；
11.Tian H, Lu Y, Shah SP, Hong S. 14S,21R-dihydroxydocosahexaenoic acid remedies impaired healing and mesenchymal stem cell functions in diabetic wounds. J Biol Chem. 2011, 286(6):4443-53；
12.Tian H, Lu Y, Shah SP, Hong S. Novel 14S,21-dihydroxy-docosahexaenoic acid rescues wound healing and associated angiogenesis impaired by acute ethanol intoxication/exposure. J Cell Biochem. 2010; 111(2):266-73；
13.Lu Y, Tian H, Hong S. Novel 14,21-dihydroxy-docosahexaenoic acids: structures, formation pathways, and enhancement of wound healing. J Lipid Res. 2010; 51(5):923-32；
14.Tian H, Lu Y, Sherwood AM, Hongqian D, Hong S. Resolvins E1 and D1 in choroid-retinal endothelial cells and leukocytes: biosynthesis and mechanisms of anti-inflammatory actions. Invest Ophthalmol Vis Sci. 2009, 50(8):3613-20