导师姓名： 李生慧 专业代码： 100400
性别： 女 专业名称： 公共卫生与预防医学
培养单位： 公共卫生学院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼专业学位硕导
联系方式： lsh9907@163.com
邮编： 邮箱地址： Lsh9907@163.com

研究方向 (点击浏览详细信息)
1. 围孕期睡眠健康效应研究
2. 气候、环境综合因素对儿童早期发育的影响

社会任职
上海预防医学杂志 编委
中国儿童保健杂志 特邀编委
上海市预防医学会 青年委员
中国学校卫生杂志 编委

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 褪黑素激活Nodal/TGF-β信号通路在围孕期睡眠影响子代心脏发育中的作用机制研 国家自然科学基金委 2019-01~2022-12 57万元 课题负责人
### 家-园联动促进学龄前儿童健康管理 上海市教育委员会 2019-01~2019-12 100万元 课题负责人
** 气候变化对儿童过敏性疾病发生的影响及应对策略的综合研究 上海市科委 2018-06~2021-06 15万元 子课题负责人
PKJ2017-Y01 环境暴露与DNMT基因多态性在先天性心脏病发生中的交互作用研究 上海市浦东新区科技发展基金 2017-07~2020-06 24万元 课题负责人
### 基于数学模型的流体力学技术在先天性心脏病外科术式优化中的应用研究 上海交通大学医学院 2017-06~2019-12 10万元 课题负责人
HX0251 GAS7在先天性心脏病发病中的作用机制研究 GAS7在先天性心脏病发病中的作用机制研究 2017-04~2019-04 12万元 课题负责人
XH1605 胆道恶性肿瘤靶向治疗多中心临床研究 上海交通大学附属新华医院 2017-01~2019-12 20万元 课题参与人
** 妊娠期SDB对母婴健康的前瞻性流行病学研究及分子生物和表观遗传机制探讨 国家自然科学基金委 2017-01~2020-12 60万元 课题负责人
GWDTR201222 REM睡眠剥夺对幼鼠肝脏Rev-erb基因表达的调控研究 上海市卫生局 2012-01~2015-01 30万元 课题负责人
** 睡眠对青少年执行功能和情绪记忆发育的影响及神经机制研究 国家自然科学基金面上项目 2011-01~2014-12 36万元 课题负责人
09YZ92 REM睡眠对幼鼠海马突触可塑性的影响及分子机制研究 上海市教委 2009-01~2011-12 8万元 课题负责人
** 学龄儿童睡眠健康流行病学调查及相关基础研究 国家自然基金委,面上项目 2008-01~2010-12 15万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Chen Y,?Zhao A,?Xia Y,?Lyu J,?Ye X, Liu N,?Li S. （通讯作者） In the Big Picture of COVID-19 Pandemic: What Can Sleep Do. Sleep Med. 2020 72:109-110
Lyu J, Zhu Q, Tong S, Su M, Li S* （通讯作者）,Hua J. Trajectories of sleep quality and associations with excessive gestational weight gain during pregnancy. Sleep and Biological Rhythms. 2020 18:249-257
Hung L, Lyu J, Long Z, Xia Y, Chen Y, Ye X, Li S （通讯作者） Gender-specific longitudinal association of sleep duration with blood pressure among children: evidence from CHNS 2004-2015. Int J Hypertens 2020 7:1-9
Lyu J, Ye X, Chen Y, Xia Y, Zhu J, Tong S, Yong Y, Qu J, Li S*. （通讯作者） Children's Sleep May Depend on Maternal Sleep Duration During Pregnancy: A Retrospective Study. Nat Sci Sleep. 2020 12:197-207.
Xia YQ, Zhao KN, Zhao AD, Zhu JZ, Hong HF, Wang YL,?Li SH （通讯作者） Associations of maternal upper respiratory tract infection/influenza during early pregnancy with congenital heart disease in offspring: evidence from a case-control study and meta-analysis. BMC Cardiovasc Disord. 2019 19:227
Lyu J, Zhao K, Xia Y, Zhao A, Yin Y, Hong H, Li S Associations between maternal social support and stressful life event with ventricular septal defect in offspring: a case-control study BMC Pregnancy Childbirth 2019 19:1
Kena Zhao, Jinwen Zhang, Zengqiang Wu, Xiaoming Shen, Shilu Tong, Shenghui Li （通讯作者） The relationship between insomnia symptoms and school performance among 4966 adolescents in Shanghai, China. Sleep Health 2019 e15
Zhao A, Zhao K, Xia Y, Yin Y, Zhu J, Hong H, Li S. （通讯作者） Exploring associations of maternal?sleep?during periconceptional period with congenital heart disease in offspring Birth Defects Res 2019 920-931
Li S （通讯作者）, Wang J, Xu Z, Wang X, Xu G, Zhang J, Shen X, Tong S. Exploring associations of maternal exposure to ambient temperature with duration of gestation and birth weight: a prospective study. BMC Pregnancy Childbirth. 2018 e513
Li L, Zhao K, Hua J, Li S （通讯作者） Association between Sleep-disordered Breathing (SDB) during Pregnancy and Maternal and Fetal Outcomes: An Updated Systematic Review and Meta-analysis. Front Neurol 2018 21
Zhang JW,?Branch W,?Hoffman M,?De Jonge A,?Li SH （通讯作者）,?Troendle J,?Zhang J. In which?groups?of?pregnant?women?can the?caesarean?delivery?rate?likely?be?reduced?safely?in the?USA? BMJ Open 2018 e021670
Li S （通讯作者）, Hua J, Hong H, Wang Y, Zhang J Interpregnancy Interval, Maternal Age, and Offspring’s BMI and Blood Pressure at 7 Years of Age J Hum Hypertens 2018 23
Zhang J, Xu Z, Zhao K, Chen T, Ye X, Shen Z, Wu Z, Zhang J, Shen X, Li S. （通讯作者） Sleep habits, sleep problems, sleep hygiene, and their associations with mental health problems among adolescents J Am Psychiatr Nurses Assoc 2017 7 [Epub ahead of print]
Li S,?Liu R,?Arguelles L,?Wang G,?Zhang J,?Shen X,?Wang X Adiposity?trajectory and its associations with plasma?plasma?adipokine?levels?in?children?and adolescents-A prospective cohort study. Obesity 2016 24:408-416
Li L, Xu Z, Jin X, Yan C, Jiang F, Tong S, Shen X, Li S (Corresponding author). （通讯作者） Sleep-disordered breathing and asthma: evidence from a large multicentric epidemiological study in China Respir Res 2015 2015 May 10;16:56. doi: 10.1186/s12931-015-0215-5
Zhang J, Jin X, Yan C, Jiang F, Shen X, Li S （通讯作者） Short sleep duration as a risk factor for childhood overweight/obesity: a large multicentric epidemiologic study in China Sleep Health 2015 1(1):184-190
Li S, Yang Q, Chen Z, Jin X, Jiang F, Shen X. Homework schedule: an important factor associated with shorter sleep duration among chinese school-aged children Behav Sleep Med 2014 3;12(5):389-97
Chen T, Zhang J, Wu Z, Shen Z （通讯作者）, Li S (Corresponding author) Short sleep duration in Chinese adolescents: biological, environmental and behavioral predictors Sleep Med 2014 15(11):1345-53
Li L, Ren J, Shi L, Jin X, Yan C, Jiang F, Shen X, Li S (Corresponding author) （通讯作者） Frequent nocturnal awakening in children: prevalence, risk factors, and associations with subjective sleep perception and daytime sleepiness BMC Psychiatry. 2014 14:204.
Li S, Arguelles L, Jiang F, Chen W, Jin X, Yan C, Tian Y, Hong X, Qian C, Zhang J, Wang X, Shen X Sleep, school performance, and a school-based intervention among school-aged children: a sleep series study in China PLoS One 2013 10;8(7):e67928
Li S, Huang H, Xu G, Cai Y, Huang F, Ye X Substance use, risky sexual behaviors, and their associations in a Chinese sample of senior high school students BMC Public Health 2013 4;13:295
Li S, Jin X, Yan C, Wu S, Jiang F, Shen X Habitual Snoring in school-aged children: environmental and biological predictors Respir Res 2010 19;11:144
Li S, Huang H, Xu G, Cai Y, Shi R, Shen X. Evaluation of a school-based HIV/AIDS peer-led prevention programme: the first intervention trial for children of migrant workers in China Journal of STD & AIDS 2010 21: 82-86
Li S, Jin X, Wu S, Jiang F, Yan C, Shen X Risk Factors Associated with Short Sleep Duration among Chinese School-aged Children Sleep Med 2010 11(9):907-916
Li S, Huang H, Xu G, Cai Y, Shi R, Shen X HIV/AIDS-related knowledge, sources, and perceived need among senior high school students: a cross-sectional study in China Journal of STD & AIDS 2009 20: 561-565
Li S, Jin X, Yan C, Wu S, Jiang F, Shen X Factors associated with bed and room sharing in Chinese school-aged children Child: care, health and development. 2009 35:171-177.
Li S, Huang H, Xu G, Cai Y, Shi R, Shen X HIV/AIDS-related knowledge, sources, and perceived need among senior high school students: a cross-sectional study in China Journal of STD & AIDS 2009 20: 561-565.
Li S, Huang H, Xu G, Cai Y, Shi R, Shen X Sexual Behaviors and Correlates among Adolescents of Migrant Workers in China: A Cross-Sectional study BMC Public Health 2009 9:195.
Li S, Jin X, Yan C, Wu S, Jiang F, Shen X Sleep Problems in Chinese School-Aged Children With a Parent-Reported History of ADHD J Atten Disord 2009 13:18-26
Li S, Tian Y, Ding Y, Yan C, Shen X The effects of rapid eye movement sleep deprivation and recovery on spatial reference memory of young rats Learn Behav 2009 37:246-53