导师姓名： 谢和辉 专业代码： 100400
性别： 男 专业名称： 公共卫生与预防医学
培养单位： 公共卫生学院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式： xhhtom@263.net
邮编： 邮箱地址： xhhtom@263.net

研究方向 (点击浏览详细信息)
心脑血管药理学和毒理学

社会任职
《Front Pharmacol》 Review Editor
中国药理学会心血管专业委员会会员
中国药理学会会员
上海市药理学会会员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 长期摄入糖替代品加重小鼠脑缺血损伤的血管新生机制研究 国家自然科学基金 2019-01~2022-12 57万元 课题负责人
2014CB542403 线粒体应激在糖尿病继发血管内皮细胞损伤和修复中的作用及干预措施 973计划子课题 2014-01~2018-12 500万元 课题参与人
** 二氯乙酸钠改善糖尿病小鼠内皮祖细胞功能及其在脑缺血损伤治疗中的应用 国家自然科学基金 2014-01~2017-12 80万元 课题负责人
** MnSOD缺陷引起的内皮祖细胞功能障碍加重小鼠脑缺血损伤 国家自然科学基金 2012-01~2015-12 60万元 课题负责人
** 低肾素性高血压小鼠内皮祖细胞功能失常的TSP-1机制 国家自然科学基金 2010-01~2012-12 35万元 课题负责人
** 氧化应激与去氧皮质酮/盐高血压小鼠内皮祖细胞数量减少 国家自然科学基金 2008-01~2010-12 22万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Peng C, Dong XH, Liu JL, Tao YL, Xu CF, Wang LP, Liu CL, Su DF, Tao X, Zhang C, Chen AF, Xie HH （通讯作者） A Preventive Injection of Endothelial Progenitor Cells Prolongs Lifespan in Stroke-prone Spontaneously Hypertensive Rats Clin Sci (Lond) 2018 132: 1797–1810
Peng C, Wang LP, Tao X, Dong XH, Xu CF, Jiang Y, Liu CL, Ma HF, Zhang C, Chen AF, Xie HH （通讯作者） Preventive cold acclimation augments the reparative function of endothelial progenitor cells in mice Cell Physiol Biochem 2018 45: 175-191
Dong XH, Peng C, Zhang YY, Tao YL, Tao X, Zhang C, Chen AF, Xie HH （通讯作者） Chronic exposure to subtherapeutic antibiotics aggravates ischemic stroke outcome in mice EBiomedicine 2017 24: 116-126.
Xin B, Liu CL, Yang H, Peng C, Dong XH, Zhang C, Chen AF, Xie HH （通讯作者） Prolonged fasting improves endothelial progenitor cell-mediated ischemic angiogenesis in mice Cell Physiol Biochem 2016 40: 693-706
Wang LP, Jiang Y, Yang H, Peng C, Zhang C, Tao X, Xie HH （通讯作者） Combination therapy of nifedipine and sulphonylureas exerts a mutual antagonistic effect on the endothelial cell dysfunction induced by hyperglycaemia linked to vascular disease Cell Physiol Biochem 2016 38: 2337-2347
Dong XH, Sun X, Jiang GJ, Chen AF, Xie HH （通讯作者） Dietary intake of sugar substitutes aggravates cerebral ischemic injury and impairs endothelial progenitor cells in mice Stroke 2015 46: 1714-18
Ma J, Peng C, Guo W, Dong YF, Dong XH, Sun X, Xie HH （通讯作者） A modified model of middle cerebral artery electrocoagulation in mice CNS Neurosci Ther 2012 18: 796-798
Shang W, Han P, Yang CB, Gu XW, Xu LP, Fu ST, Su DF, Xie HH （通讯作者） Synergism of irbesartan and amlodipine on hemodynamic amelioration and organ protection in spontaneously hypertensive rats Acta Pharmacol Sin 2011 32: 1109-1115
Ni M, Yang ZW, Li DJ, Li Q, Zhang SH, Su DF, Xie HH （通讯作者）, Shen FM A potential role of alpha-7 nicotinic acetylcholine receptor in cardiac angiogenesis in a pressure overload rat model J Pharmacol Sci 2010 114: 311-319
Xie HH, Zhou S, Chen D, Channon KM, Su DF, Chen AF GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension Hypertension 2010 56:1137-1144
Xie HH, Zhang XF, Chen YY, Shen FM, Su DF Synergism of Hydrochlorothiazide and Nifedipine on Blood Pressure Variability Reduction and Organ Protection in Spontaneously Hypertensive Rats Hypertens Res 2008 31: 685–691
Xie HH, Shen FM, Xu LP, Han P, Miao CY, Su DF Reduction of blood pressure variability by combination therapy in spontaneously hypertensive rats J Hypertens 2007 25: 2334–44
Xie HH, Shen FM, Zhang XF, Jiang YY, Su DF Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs Eur J Pharmacol 2006 543: 77-82
Shen FM, Xie HH （共同第一作者）, Ling G, Xu LP, SU DF Synergism of atenolol and amlodipine on lowering and stabilizing blood pressure in 2K1C renovascular hypertensive rats Acta Pharmacol Sin 2005 26: 1303-8
Xie HH, Miao CY, Jiang YY, Su DF Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats J Hypertens 2005 23: 193-201
Xie HH, Shen FM, Miao CY, Su DF Blood pressure, baroreflex sensitivity and end organ damage in hybrid offspring of SHR and SD rats Acta Pharmacol Sin 2005 26: 1049-56
Xie HH, Shen FM, Cao YB, Li HL, Su DF Effects of low-dose ketanserin on blood pressure variability, baroreflex sensitivity and end-organ damage in spontaneously hypertensive rats Clin Sci (Lond) 2005 108: 547-52
Xie HH, Chen YY, Miao CY, Shen FM, Su DF Effects of long-term treatment with candesartan on hemodynamics and organ damage in spontaneously hypertensive rats Cardiovasc Drugs Ther 2005 19: 391-7
Xie HH, Miao CY, Liu JG, Su DF. Effects of Long-Term Treatment with Candesartan on Organ Damages in Sinoaortic Denervated Rats J Cardiovasc Pharmacol 2003 41: 325-31
Xie HH, Miao CY, Liu JG, Su DF Importance of blood pressure variability in the organ protection in spontaneously hypertensive rats treated with combination of nitredipine and atenolol Acta Pharmacol Sin 2002 23: 1199-204