导师姓名： Tomasz Maj 专业代码： 100214
性别： 男 专业名称： 肿瘤学
培养单位： 附属仁济医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： 上海市浦东新区浦建路160号仁济医院
邮编： 200127 邮箱地址： tomasz_maj@163.com

研究方向 (点击浏览详细信息)
immunology, tumor immunology, autoimmunity, immune tolerance

社会任职

科研项目

学术论文 作者论文标题期刊名出版年卷期页码
Lazarus J, Oneka MD, Barua S, Maj T, Lanfranca MP, Delrosario L, Sun L, Smith JJ, D'Angelica MI, Shia J, Fang JM, Shi J, Di Magliano MP, Zou W, Rao A, Frankel TL. Mathematical Modeling of the Metastatic Colorectal Cancer Microenvironment Defines the Importance of Cytotoxic Lymphocyte Infiltration and Presence of PD-L1 on Antigen Presenting Cells Annals of Surgical Oncology 2019 26(9):2821-2830
Maj T, Zou W. Rewiring regulatory T cells for tumour killing Nature Biomedical Engineering 2019 3(10):766-767
Crespo J, Wu K, Li W, Kryczek I, Maj T, Vatan L, Wei S, Opipari AW, Zou W. Human Naive T Cells Express Functional CXCL8 and Promote Tumorigenesis Journal of Immunology 2018 201(2):814-820
Lazarus J, Maj T, Smith JJ, Perusina Lanfranca M, Rao A, D'Angelica MI, Delrosario L, Girgis A, Schukow C, Shia J, Kryczek I, Shi J, Wasserman I, Crawford H, Nathan H, Pasca Di Magliano M, Zou W, Frankel TL. Spatial and phenotypic immune profiling of metastatic colon cancer JCI Insight 2018 3(22):pii: 121932
Xia H, Wang W, Crespo J, Kryczek I, Li W, Wei S, Bian Z, Maj T, He M, Liu RJ, He Y, Rattan R, Munkarah A, Guan JL, Zou W. Suppression of FIP200 and autophagy by tumor-derived lactate promotes naive T cell apoptosis and affects tumor immunity.Suppression of FIP200 and autophagy by tumor-derived lactate promotes na?ve T cell apoptosis and affects tumor immunity Science Immunology 2017 2(17):pii: eaan4631
Crespo J, Vatan L, Maj T, Liu R, Kryczek I, Zou W. Phenotype and tissue distribution of CD28H+ immune cell subsets Oncoimmunology 2017 6(12):e**
Maj T （共同第一作者）, Wang W, Crespo J, Zhang H, Wang W, Wei S, Zhao L, Vatan L, Shao I, Szeliga W, Lyssiotis C, Liu JR, Kryczek I, Zou W. Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor Nature Immunology 2017 18(12):1332-1341
Zhao E, Maj T （共同第一作者）, Kryczek I, Li W, Wu K, Zhao L, Wei S, Crespo J, Wan S, Vatan L, Szeliga W, Shao I, Wang Y, Liu Y, Varambally S, Chinnaiyan AM, Welling TH, Marquez V, Kotarski J, Wang H, Wang Z, Zhang Y, Liu R, Wang G, Zou W. Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction Nature Immunology 2016 17(1):95-103
Wang W, Kryczek I, Dostál L, Lin H, Tan L, Zhao L, Lu F, Wei S, Maj T, Peng D, He G, Vatan L, Szeliga W, Kuick R, Kotarski J, Tarkowski R, Dou Y, Rattan R, Munkarah A, Liu JR, Zou W. Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer Cell 2016 165(5):1092-1105
Hossain F, Al-Khami AA, Wyczechowska D, Hernandez C, Zheng L, Reiss K, Valle LD, Trillo-Tinoco J, Maj T, Zou W, Rodriguez PC, Ochoa AC. Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Cancer Immunology Research 2015 3(11):1236-47
Maj T, Zou W. Dendritic cells are stressed out in tumor Cell Research 2015 25(9):989-90
Maj T, Slawek A, Chelmonska-Soyta A CD80 and CD86 costimulatory molecules differentially regulate OT-II CD4? T lymphocyte proliferation and cytokine response in cocultures with antigen-presenting cells derived from pregnant and pseudopregnant mice Mediators of Inflammation 2014 2014:769239
Maj T, Wei S, Welling T, Zou W. T cells and costimulation in cancer Cancer Journal 2013 19(6):473-82
Kurzepa-Skaradzinska A, Lusiak-Szelachowska M, Skaradzinski G, Jonczyk-Matysiak E, Weber-Dabrowska B, Zaczek M, Maj T, Slawek A, Rymowicz W, Klak M, Miedzybrodzki R, Gorski A. Influence of bacteriophage preparations on intracellular killing of bacteria by human phagocytes in vitro Viral Immunology 2013 26(2):150-62
Kurzepa-Skaradzinska A, Skaradzinski G, Weber-Dabrowska B, Zaczek M, Maj T, Slawek A, Switalska M, Maciejewska M, Wietrzyk J, Rymowicz W, Gorski A. Influence of bacteriophage preparations on migration of HL-60 leukemia cells in vitro Anticancer Research 2013 33(4):1569-74
Slawek A, Maj T （共同第一作者）, Chelmonska-Soyta A. CD40, CD80, and CD86 costimulatory molecules are differentially expressed on murine splenic antigen-presenting cells during the pre-implantation period of pregnancy, and they modulate regulatory T-cell abundance, peripheral cytokine response, and pregnancy outcome American Journal of Reproductive Immunology 2013 70(2):116-26
Slawek A, Maj T, Chelmonska-Soyta A. Antigen presenting cells costimulatory signaling during pre-implantation pregnancy Postepy Higieny i Medycyny Doswiadczalnej 2012 66:674-82
Maj T, Slawek A, Kaleta-Kuratewicz K, Chelmonska-Soyta A. 17beta-Estradiol and interferon tau interact in the regulation of the immune response in a model of experimental autoimmune orchitis Journal of Interferon and Cytokine Research 2011 31(11):825-37
Maj T, Switala-Jelen K, Miazek A, Szafarowicz-Basta B, Kiczak L, Slawek A, Chelmonska-Soyta A. Effects of tamoxifen on estrogen receptor-α level in immune cells and humoral specific response after immunization of C3H/He male mice with syngeneic testicular germ cells (TGC) Autoimmunity 2011 44(6):520-30
Piesta A, Maj T （共同第一作者）, Chelmonska-Soyta A. The influence of mating on estrogen receptor alpha protein level in spleen and uterine macrophages in female mice Reproductive Immunology 2009 9(3):225-40
Maj T, Chelmonska-Soyta A. Pleiotropy and redundancy of STAT proteins in early pregnancy Reproduction in Domestic Animals 2007 42(4):343-5