导师姓名： 韩兵 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属第九人民医院 三级学科/
专业领域： 内分泌与代谢病
导师类型： 硕士生导师 专业学位导师：
联系方式： 上海市黄浦区制造局路639号 内分泌科
邮编： 200011 邮箱地址： hanbing1423@163.com

研究方向 (点击浏览详细信息)
遗传相关内分泌疾病

社会任职
现代医药杂志编委
上海市医学会糖尿病学分会青年委员
美国内分泌学会会员
白求恩精神研究会内分泌和糖尿病分会理事

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** DUOX2基因突变导致先天性甲状腺功能减退症的遗传模式及其临床特征研究 国家自然科学基金 2017-01~2020-12 58万元 课题负责人
** 黄体生成素受体的选择性剪切在多囊卵巢综合症发病中的作用机制研究 国家自然科学基金 2013-01~2015-12 23万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Han B, Cheng T, Zhu H, Yu J, Zhu WJ, Song HD, Yao H, Qiao J. Genetic Analysis of 25 Patients with 5α-Reductase Deficiency in Chinese Population. Biomed Res Int. 2020 2020:**.
Wang N, Zhu W, Han B （共同第一作者）, Wang H, Zhu H, Chen Y, Chen Y, Liu J, Liu Y, Zhao S, Song H, Qiao J. Inherited Missense Mutation Occurring in Arginine76 of the SRY Gene Does Not Account for Familial 46, XY Sex Reversal. J Clin Endocrinol Metab. 2020 105(5):dgaa109.
Zhang M, Zhang L, Li Y, Sun F, Fang Y, Zhang R, Wu J, Zhou G, Song H, Xue L, Han B （通讯作者）, Zheng C. Exome sequencing identifies somatic mutations in novel driver genes in non-small cell lung cancer. Aging (Albany NY). 2020 2020 Jul 6;12.
Chen Y, Cheng J, Chen Y, Wang N, Xia F, Chen C, Han B （通讯作者）, Lu Y. Association between serum vitamin D and uric acid in the eastern Chinese population: a population-based cross-sectional study. BMC Endocr Disord. 2020 20(1):79.
Han B, Wang N, Chen Y, Li Q, Zhu C, Chen Y, Lu Y. Prevalence of hyperuricaemia in an Eastern Chinese population: a cross-sectional study. BMJ Open. 2020 10:e035614.
Bing Han, Chi Chen, Yi Chen, Ningjian Wang, Jie Yu, Jing Cheng, Yingchao Chen, Chunfang Zhu, Yingli Lu Relationship between Gene Polymorphisms and Urine Iodine Levels on Susceptibility to Thyroid Peroxidase Antibody Positivity in the Chinese Population. European Thyroid Journal. 2020 21 April 2020.
Xu B, Yu J, Lu Y, Han B. （通讯作者） Primary hyperparathyroidism presenting as a brown tumor in the mandible: a case report. BMC Endocr Disord. 2020 20(1):6.
Zhu W, Han B （共同第一作者）, Fan M, Wang N, Wang H, Zhu H, Cheng T, Zhao S, Song H, Qiao J. Oxidative stress increases the 17,20-lyase-catalyzing activity of adrenal P450c17 through p38α in the development of hyperandrogenism. Mol Cell Endocrinol. 2019 484:25-33.
Han B, Li Q, Wang N, Chen Y, Zhu C, Chen Y, Xia F, Cang Z, Lu M, Meng Y, Chen C, Lu Y. Sexual Dimorphism for the Association between Vitamin D and Insulin Resistance in Chinese People. Int J Endocrinol. 2018 2018:**.
Han B, Chen Y, Cheng J, Li Q, Zhu C, Chen Y, Xia F, Wang N, Lu Y. Comparison of the Prevalence of Metabolic Disease Between Two Types of Urbanization in China. Front Endocrinol (Lausanne). 2018 9:665.
Han B, Cheng T, Ye L, Sui C, Yang L, Lin D, Qiao J, Lu Y. Comparison between acute kidney injury (AKI) and non-AKI patients secondary to severe hypothyroidism. Clin Case Rep. 2018 6(6):1066-1069.
Liu W, Han B （共同第一作者）, Zhu W, Cheng T, Fan M, Wu J, Yang Y, Zhu H, Si J, Lyu Q, Chai W, Zhao S, Song H, Kuang Y, Qiao J. Polymorphism in the Alternative Donor Site of the Cryptic Exon of LHCGR: Functional Consequences and Associations with Testosterone Level. Sci Rep. 2017 7:45699.
Zhang MM, Sun F, Cui B, Zhang LL, Fang Y, Li Y, Zhang RJ, Ye XP, Ma YR, Han B （通讯作者）, Song HD. Tumor-suppressive function of UNC5D in papillary thyroid cancer. Oncotarget. 2017 8(56):96126-96138.
Han B, Wang X, Wang N, Li Q, Chen Y, Zhu C, Chen Y, Xia F, Pu X, Cang Z, Zhu C, Lu M, Meng Y, Guo H, Chen C, Tu W, Li B, Hu L, Wang B, Lu Y. Investigation of vitamin D status and its correlation with insulin resistance in a Chinese population. Public Health Nutr. 2017 20(9):1602-1608.
Han B, Xue L, Yang C. Giant gouty tophi in the hands. Lancet Diabetes Endocrinol. 2017 5(2):156.
Han B, Xue L, Fan M, Zhao S, Liu W, Zhu H, Cheng T, Lu Y, Cheng K, Song H, Liu Y, Qiao J. Clinical and molecular manifestation of fifteen 17OHD patients: a novel mutation and a founder effect. Endocrine. 2016 53(3):784-90.
Han B, Zhai HL, Yu J, Xia FZ, Lu YL. Diabetes mellitus associated with pancreatic somatostatin tumor:A case report. Journal of Clinical and Translational Endocrinology: Case Reports 2016 2: 20-22.
Zhang L, He J, Han B （共同第一作者）, Lu L, Fan J, Zhang H, Ge S, Zhou Y, Jia R, Fan X. Novel FOXC2 Mutation in Hereditary Distichiasis Impairs DNA-Binding Activity and Transcriptional Activation. Int J Biol Sci. 2016 12(9):1114-20.
Wang N, Wang X, Han B （共同第一作者）, Li Q, Chen Y, Zhu C, Chen Y, Xia F, Cang Z, Zhu C, Lu M, Meng Y, Chen C, Lin D, Wang B, Jensen MD, Lu Y. Is Exposure to Famine in Childhood and Economic Development in Adulthood Associated With Diabetes? J Clin Endocrinol Metab. 2015 100(12):4514-23.
Zhu H, Liu W, Han B （共同第一作者）, et al. Phenotypic and molecular characteristics in eleven Chinese patients with 5α-reductase Type 2 deficiency. Clin Endocrinol (Oxf). 2014 81(5):711-20.
Xue L, Han B （共同第一作者）, Pan C, Song H. The association of SCGB3A2 polymorphisms with the risk of Graves' disease: a meta-analysis. Endocrine. 2014 45(3):365-9.
Xue LQ, Han B （共同第一作者）, Liu W, et al. Identification of a novel mutation in CYP17A1 gene. Transl Res. 2013 161(1):44-9.
Han B, Liu B, Xue L, et al. Treatment of acute multiorgan dysfunction occurring in congenital adrenal hyperplasia. Endocrine. 2013 43(2): 462-3.
Zheng CX, Gu ZH, Han B （共同第一作者）, et al. Whole-exome sequencing to identify novel somatic mutations in squamous cell lung cancers. Int J Oncol. 2013 43(3):755-64.
Han B, Liu W, Zuo CL, et al. Identifying a novel mutation of CYP17A1 gene from five Chinese 17α-hydroxylase/17, 20-lyase deficiency patients. Gene. 2013 516(2):345-50.
Han B, Song ZY, Wu JJ, et al. A novel intronic mutation and a missense mutation of MEN1 identified in two Chinese families with multiple endocrine neoplasia type 1(MEN1). J Endocrinol Invest. 2013 36(3):162-7.
Han B, Wang ZQ, Xue LQ, et al. Functional study of an aberrant splicing variant of the human luteinizing hormone (LH) receptor. Mol Hum Reprod. 2012 18(3):129-135.
Qiao J, Han B （共同第一作者）, Liu BL, et al. A unique exonic splicing mutation in the CYP17A1 gene as the cause for steroid 17{alpha}-hydroxylase deficiency. Eur J Endocrinol. 2011 164(4):627-633.
Han B, Zhou X, Zhang RX, et al. Mutations of the epidermal growth factor receptor gene in NSCLC patients. Oncol lett. 2011 (2)6: 1233-1237.
Wang XM, Zhang MX, Zhao L, Han B （通讯作者）, Xu P, Xue M. The Starling mechanism of the urinary bladder contractile function and the influence of hyperglycemia on diabetic rats. J Diabetes Complications. 2010 24(2):121-128.
Qiao J, Han B （共同第一作者）, Liu BL, et al. A splice site mutation combined with a novel missense mutation of LHCGR cause male pseudohermaphroditism. Hum Mutat. 2009 30(9):E855-65.