导师姓名： 王祥 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属第九人民医院 三级学科/
专业领域： 骨外
导师类型： 硕士生导师 专业学位导师： 兼
联系方式： wx**@outlook.com
邮编： 201900 邮箱地址： wx**@outlook.com

研究方向 (点击浏览详细信息)
骨与关节损伤；骨性关节炎

社会任职
中国医师协会显微外科分会开放性骨折专业委员会委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
17ZR** TGFβ诱导TIMP3表达中ERK强化TGFβ/Smad信号的相关机制探讨 上海市科学技术委员会 2017-05~2020-05 20万元 课题负责人
** ERK1与ERK2在TGF 促进软骨基质合成并抑制其降解中作用与调控机理研究 国家自然科学基金青年基金项目 2012-01~2014-12 22万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Jian Wang,Jie Ma,Jian?Hua Gu,Fu?Yong Wang,Xiu?Shuai Shang,Hai?Rong Tao,Xiang Wang （通讯作者） Regulation of type II collagen, matrix metalloproteinase-13 and cell proliferation by interleukin-1β is mediated by curcumin via inhibition of NF-κB signaling in rat chondrocytes Molecular Medicine Reports 2017 16: 1837-1845
Yanhui Zhu,Jianhua Gu,Tong Zhu,Chen Jin,Xiaopeng Hu,Xiang Wang （通讯作者） Crosstalk between Smad2/3 and specific isoforms of ERK in TGF-b1-induced TIMP-3 expression in rat chondrocytes J. Cell. Mol. Med. 2017 21(9):1781-1790
Zhu Yanhui,Tao Hairong,Jin Chen,Liu Yonzhang,Lu Xiongwei,Hu Xiaopeng,Wang Xiang （通讯作者） Transforming growth factorbeta1 induces type II collagen and aggrecan expression via activation of extracellular signalregulated kinase 1/2 and Smad2/3 signaling pathways Molecular Medicine Reports 2015 12（4）：5573-5579
Wang Xiang,Tao Hairong,Zhu Yanhui,Lu Xiongwei,Hu Xiaopeng Management of Postoperative Spondylodiscitis with and without Internal Fixation Turkish Neurosurgery 2015 25（4）：513-518
Xiang Wang,Yanhui Zhu,Hairong Tao,Chen Jin,Yonzhang Liu,Xiongwei Lu,Xiaopeng Hu,Cunyi Fan Interaction of ERK1/2 and Smad2/3 signaling pathways in TGF-b1-induced TIMP-3 expression in rat chondrocytes Archives of Biochemistry and Biophysics 2014 564：229-236
Xiang Wang,Chunyang Wang,Qijun Feng,Yang Zon,Cunyi Fan Femoral lock plant alone for ipsilateral subtrochanteric, supracondylar, and intercondylar fracture Injury Extra 2012 43（8）：57-59
Wang Xiang,Zhou Jianshen,Zhang Changchun,Liu Zhenhua Single-stage anterior debridement and fusion with autografting and internal fixation for pyogenic lumbar spondylodiscitis Arch Orthop Trauma Surg 2012 132（4）：487-493
Wang Xiang,Li Fengfeng,Fan Cunyi,Wang Chunyang,Ruan Hongjiang Effects and relationship of ERK1 and ERK2 in interleukin-1beta-induced alterations in MMP3, MMP13, type II collagen and aggrecan expression in human chondrocytes Int J Mol Med 2011 27（4）：583-589
Wang Xiang,Li Fengfeng,Fan Cunyi,Wang Chunyang,Ruan Hongjiang Analysis of isoform specific ERK signaling on the effects ofinterleukin-1beta on COX-2 expression and PGE2 production in human Biochem Biophys Res Commun 2010 402（1）：23-29
Wang Xiang,Zhou Jianshen,Zhang Changchun,Liu Zhen hua The single transoral approach for Os odontoideum with irreducible atlantoaxial dislocation European Spine Journal 2009 19（suppl2）：s91-s95