导师姓名： 刘昕 专业代码： 100301
性别： 女 专业名称： 口腔基础医学
培养单位： 附属第九人民医院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式： liuxin0556@163.com
邮编： 200023 邮箱地址： liuxin0556@163.com

研究方向 (点击浏览详细信息)
口腔（生物）材料的开发及生物学评价

社会任职
中华口腔医学会口腔材料专委会委员
全国纳米医疗器械生物学评价分技委委员
上海市口腔医学会口腔材料专委会常委
上海市生物医学工程学会生物材料专委会委员
全国医疗卫生材料及敷料标准化技术归口单位专家组专家

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 可控带隙调制的MnO2/SiO2光热纳米复合材料的构筑及其多模式抗肿瘤效应与机制研究 国家自然科学基金面上项目 2020-01~2023-12 55万元 课题负责人
18PJD024 新型鱿鱼软骨II型胶原的开发及其缓解退行性骨关节炎的作用机理 上海市浦江人才计划 2018-09~2020-08 20万元 课题负责人
** 生物样品中无机元素ICP-MS分析方法研究及其在纳米材料安全性评价中的应用探讨 上海市科委科学仪器领域项目 2016-09~2018-09 10万元 课题负责人
** 无机纳米颗粒致血脑屏障损伤的潜在风险和免疫机制 国家自然科学基金青年项目 2013-01~2015-12 23万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Meilu Dai,Baiyan Sui,Yujie Hua, Yiqing Zhang,Bingkun Bao,Qiuning Lin*,Xin Liu* （通讯作者）,Linyong Zhu,Jiao Sun*. A well defect-suitable and high-strength biomimetic squid type II gelatin hydrogel promoted in situ costal cartilage regeneration via dynamic immunomodulation and direct induction manners. Biomaterials 2020 119841
Baiyan Sui#, Xin Liu# （共同第一作者）, Jiao Sun Dual-Functional Dendritic Mesoporous Bioactive Glass Nanospheres for Calcium Influx-Mediated Specific Tumor Suppression and Controlled Drug Delivery in Vivo ACS Appl. Mater. Interfaces 2018 10, 23548?23559
Meilu Dai, Baiyan Sui,Yang Xue, Xin Liu* （通讯作者）, Jiao Sun* Cartilage repair in degenerative osteoarthritis mediated by squid type II collagen via immunomodulating activation of M2 macrophages, inhibiting apoptosis and hypertrophy of chondrocytes. Biomaterials 2018 180:91-103
Xin Liu#, Baiyan Sui, Jiao Sun. Blood-brain barrier dysfunction induced by silica NPs in vitro and in vivo: Involvement of oxidative stress and Rho-kinase/JNK signaling pathways. Biomaterials 2017 121:64-82
Tian Zhou#, Xin Liu# （共同第一作者）,Baiyan Sui, Chao Liu, Xiumei Mo, Jiao Sun. Development of fish collagen/bioactive glass/chitosan composite nanofibers as a GTR/GBR membrane for inducing periodontal tissue regeneration Biomedical Materials 2017 13;12(5):055004
Ying He, Wei Wang, Xuyan Tang, Xin Liu* （通讯作者） Osteogenic induction of bone marrow mesenchymal cells on electrospun polycaprolactone/chitosan nanofibrous membrane. Dental materials journal 2017 36(3):325-332
Débora R. Lima#, Ning Jiang#, Xin Liu# （共同第一作者）,Jiale Wang, Valcinir A. S. Vulcani, Alessandro Martins, Douglas S. Machado, Richard Landers, Pedro H. C. Camargo,Alexandre Pancotti Employing Calcination as a Facile Strategy to Reduce the Cytotoxicity in CoFe2O4 and NiFe2O4 Nanoparticles ACS Appl. Mater. Interfaces 2017 9 (45), pp 39830–39838
Xin Liu# （共同第一作者）, Baiyan Sui#, Jiao Sun. Size- and shape-dependent effects of titanium dioxide nanoparticles on the permeabilization of the blood-brain barrier Journal of Materials Chemistry B 2017 5: 9558-9570
Xin Liu#, Jiao Sun* Potential proinflammatory effects of hydroxyapatite nanoparticles on endothelial cells in a monocyte-endothelial cell coculture model. International journal of nanomedicine 2014 9:1261-1273.
Xin Liu#, Jiao Sun* Time-course effects of intravenously administrated silica nanoparticles on blood coagulation and endothelial function in rats. Journal of Nanoscience and Nanotechnology 2013 13:222–228
Xin Liu#, Yang Xue, Tingting Ding, Jiao Sun* Enhancement of proinflammatory and procoagulant responses to silica particles by monocyte-endothelial cell interactions Particle and fibre toxicology 2012 9(1):36
Xin Liu#, Jiao Sun* Endothelial cells dysfunction induced by Silica nanoparticles through oxidative stress via JNK /P53 and NF-kB pathway Biomaterials 2010 31: 8198-209
Xin Liu#, Yang Xue, Jiao Sun* Indirect induction of endothelial cells injury by PU- or PTFE-mediated activation of monocytes. J BIOMAT SCI-POLYM E 2010 21:1783-97