导师姓名： 韦芳 专业代码： 100212
性别： 女 专业名称： 眼科学
培养单位： 附属第一人民医院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式：
邮编： 邮箱地址： weifang73@hotmail.com

研究方向 (点击浏览详细信息)
抗新生血管形成及在眼科疾病中的应用
糖尿病视网膜病变

社会任职

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** FBXW7调节血管内皮高糖毒性与氧化应激损伤缓解糖尿病视网膜病变的作用及机制研究 国家自然科学基金面上项目 2020-01~2023-12 55万元 课题负责人
** c-Cbl 泛素化调控JAK2/STAT3 途径对早产儿视网膜血管新生的作用研究 国家自然科学基金青年项目 2018-01~2020-12 20万元 课题参与人
13JC** 有机/无机杂化光热转换材料的设计、合成及其在癌症治疗中的应用 上海市科委基础研究领域项目 2013-09~2016-08 40万元 课题参与人
** 初步探讨艾灸疗法对肝癌患者的免疫应答microRNA调节分子的影响 上海市科委 2013-07~2015-09 10万元 课题负责人
活体成像技术在艾灸对不同肿瘤模型免疫调节机制中的应用研究 上海市科委 2011-05~2014-04 15万元 课题参与人
09ZR** Neuronatin在糖尿病性视网膜病变中的作用研究 上海市科委 2009-08~2011-07 10万元 课题参与人
** 腺病毒载体的靶向性改造 国家自然科学基金资助项目 2007-01~2009-12 27万元 课题参与人
** E2F调控的复制型腺病毒构建及其在RB肿瘤基因治疗中的应用 国家自然科学基金资助项目 2006-01~2008-12 24万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
She X, Lu X, Li T, Sun J, Liang J, Zhai Y, Yang S, Gu Q, Wei F, Zhu H, Wang F, Luo X, Sun X. Inhibition of Mitochondrial Fission Preserves Photoreceptors after Retinal Detachment. Am J Pathol 2018 188(7):1713-1722
Zhu S, Xu X, Liu K, Gu Q, Wei F, Yang X. PAPep Inhibits Secretion of Poly(I:C)-Induced Inflammatory Cytokines and ICAM-1 Expression in Corneal Fibroblasts by Suppressing the NF-κB/p38 Pathway. J Ocul Pharmacol Ther 2018 34(5):395-402.
Xiong S, Xu Y, Ma M, Wang H, Wei F, Gu Q, Xu X. Neuroprotective effects of a novel peptide, FK18, under oxygen-glucose deprivation in SH-SY5Y cells and retinal ischemia in rats via the Akt pathway. Neurochem Int 2017 108:78-90
Zhu S, Xu X, Liu K, Gu Q, Wei F, Jin H. Peptide GC31 inhibits chemokines and ICAM-1 expression in corneal fibroblasts exposed to LPS or poly(I:C) by blocking the NF-κB and MAPK pathways. Exp Eye Res 2017 164:109-117
Zhu S, Xu X, Wang L, Su L, Gu Q, Wei F, Liu K. Inhibitory effect of a novel peptide, H-RN, on keratitis induced by LPS or poly(I:C) in vitro and in vivo via suppressing NF-κB and MAPK activation. J Transl Med 2017 15(1):20
Zhouqi Meng, Fang Wei （共同第一作者）, Wujun Ma, Nuo Yu, Peiling Wei, Zhaojie Wang, Yueqin Tang, Zhigang Chen, Huiping Wang, Meifang Zhu. Design and Synthesis of “All-in-One” Multifunctional FeS2 Nanoparticles for Magnetic Resonance and Near-Infrared Imaging Guided Photothermal Therapy of Tumors. Adv Funct Mater 2016 26(45):8231–8242.
Meng Z, Wei F （共同第一作者）, Wang R, Xia M, Chen Z, Wang H, Zhu M. NIR-Laser-Switched In Vivo Smart Nanocapsules for Synergic Photothermal and Chemotherapy of Tumors. Adv Mater 2016 28(2):245-53.
Li F, Jin L, Wang H, Wei F, Bai M, Shi Q, Du L. The dual effect of ultrasound-targeted microbubble destruction in mediating recombinant adeno-associated virus delivery in renal cell carcinoma: transfection enhancement and tumor inhibition. J Gene Med 2014 16(1-2):28-39.
Wei Fang, Wang Huiping, Chen Xiafang, Li Chuanyuan, Huang Qian. Dissecting the roles of E1A and E1B in adenoviral replication and RCAd-enhanced RDAd transduction efficacy on tumor cells. Cancer Biol Ther. 2014 15(10):1358-66.
Zhou Jun-mei,Wei Fang,Liu Su-jun,Zhang Bi-meng. Study on burning temperature versus time graph of moxa sticks in a novel animal moxibustion device. J Acupunct Tuina Sci 2014 12（3）：194-198.
Huiping Wang, Fang Wei* （通讯作者）, Huiming Li, Xunda Ji, Shuxia Li, Xiafang Chen. Combination of oncolytic adenovirus and endostatin inhibits human retinoblastoma in an in vivo mouse model. Int J Mol Med 2013 31(2): 377-385.
Li-Fang Jin, Fan Li, Hui-Ping Wang, Fang Wei, Lian-Fang Du. Ultrasound targeted microbubble destruction enhances gene transduction of adeno-associated virus in a less-permissive cell type, NIH/3T3. Molecular Medicine Reports 2013 8(2):320-6.
Fang Wei, Huiping Wang, Jufeng Zhang, Xiafang Chen, Chuanyuan Li, Qian Huang. Pharmacokinetics of combined gene therapy expressing constitutive human GM-CSF and hyperthermia-regulated human IL-12. J Exp Clin Canc 2013 32(1): 5
Li-Fang Jin, Fan Li, Hui-Ping Wang, Fang Wei, Peng Qin, Lian-Fang Du. Ultrasound Targeted Microbubble Destruction Stimulates Cellular Endocytosis in Facilitation of Adeno-Associated Virus Delivery. Int J Mol Sci 2013 14(5)： 9737-9750.
Yang Liu, Zhaoqian Wang, Huiming Li, Zhaoping Wu, Fang Wei* （通讯作者）,Huiping Wang*. Role of the ERas gene in gastric cancer cells. Oncol Rep 2013 30(1):50-56.
Huiping Wang, Fang Wei （共同第一作者）, Jufeng Zhang, Feng Wang, Huiming Li, Xiafang Chen, Kuangcheng Xie, Yufei Wang, Chuanyuan Li, Qian Huang. A novel immunocompetent murine tumor model for the evaluation of RCAd-enhanced RDAd transduction efficacy. Tumor Biol 2012 33(4):1245-1253.
韦芳,王丰,刘新建,李惠明,田毓华,黄倩. 电穿孔介导免疫调节因子及血管生成抑制因子转移治疗脉络膜黑色素瘤. 中华眼底病杂志 2011 27（1）：33-36.
韦芳,王慧萍,张巨峰,李惠明. 受人E2F1启动子调控的条件复制型腺病毒载体的构建与鉴定. 山西医科大学学报 2011 42（12）：945-949.
Jufeng Zhang, Fang Wei, Huiping Wang, Huiming Li, Wei Qiu, Pengkang Ren, Xiafang Chen, Qian Huang. Potent anti-tumor activity of telomerase-dependent and HSV-TK armed oncolytic adenovirus for non-small cell lung cancer in vitro and in vivo. J Exp Clin Cancer Res 2010 20(29)：52-55.
Jufeng Zhang, Fang Wei, Huiping Wang, Huiming Li, Wei Qiu, Pengkang Ren, Xiafang Chen, Qian Huang. A novel oncolytic adenovirus expressing escherichia coli cytosine deaminase exhibits potent antitumor effect on human solid tumors. Cancer biother radio 2010 25(4)：487-495.
WEI Fang, WANG Hui-Ping, CHEN Xia-Fang, LI Chuan-Yuan, HUANG Qian. Construction and Characterization of Oncolytic Adenovirus Controlled Under Heat Shock Protein70 Gene Promoter. Progress in Biochemistry and Biophysics 2009 36(12):1536-1543.
Xunda Ji, Jufeng Zhang, Lin Cheng, Fang Wei, Huiming Li, Xinjian Liu, Xiafang Chen, Chuanyuan Li, Yufei Wang, Qian Huang. Oncolytic adenovirus delivering herpes simplex virus thymidine kinase suicide gene reduces the growth of human retinoblastoma in an in vivo mouse model. Experimental Eye Research 2009 89(2)：193-199.
Xunda Ji, Lin Cheng, Fang Wei, Huiming Li, Mengyun Wang, Yuhua Tian, Xiafang Chen, Yufei Wang, Frank Wolf, Chuanyuan Li, Qian Huang. Noninvasive Visualization of Retinoblastoma Growth and Metastasis via Bioluminescence Imaging. Invest Ophthalmol Vis Sci 2009 50(12)：5544-5551.