导师姓名： 陈仲中 专业代码： 100202
性别： 男 专业名称： 儿科学
培养单位： 附属儿童医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： chenzhongzhong@shchildren.com.cn
邮编： 邮箱地址： zhongzhongchen@aliyun.com

研究方向 (点击浏览详细信息)
泌尿生殖系统的遗传分子调控机制

社会任职

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 外生殖器发育过程中基因变异及分子调控网络导致尿道下裂的机理研究 国家自然科学基金面上项目 2020-01~2023-12 55万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Zhongzhong Chen, Xiaoling Lin, Yaping Wang, Hua Xie, Fang Chen Dysregulated expression of androgen metabolism genes and genetic analysis in hypospadias Molecular Genetics & Genomic Medicine 2020 8(8):e1346
Yunping Lei*, Sung-Eun Kim*, Zhongzhong Chen* （共同第一作者）, Xuanye Cao, Huiping Zhu, Wei Yang, Gary M. Shaw, Yufang Zheng, Ting Zhang, Hongyan Wang, Richard H. Finnell Variants Identified in PTK7 Associated with Neural Tube Defects Molecular Genetics & Genomic Medicine 2019 28:e584
Jean-Philippe Coppe, Miki Mori, Bo Pan, Christina Yau, Denise M. Wolf, Ana Ruiz-Saenz, Diede Brunen, Anirudh Prahallad, Paulien Cornelissen-Steijger, Kristel Kemper, Christian Posch, Changjun Wang, Courtney Dreyer, Oscar Krijgsman, Pei Rong Evelyn Lee, Zhongzhong Chen,..., Laura J. van ‘t Veer Mapping phospho-catalytic dependencies of therapy-resistant tumors reveals new actionable vulnerabilities Nature Cell Biology 2019 21(6):778-790
Zhongzhong Chen, Xiaoling Lin, Yunping Lei, Haitao Chen, Richard H. Finnell, Yaping Wang, Jianfeng Xu, Daru Lu, Hua Xie, Fang Chen Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13 BMC Med Genomics 2019 12(1):196
Zhongzhong Chen, Yunping Lei, Yufang Zheng, Vanessa Aguiar-Pulido, M. Elizabeth Ross, Rui Peng, Li Jin, Ting Zhang, Richard H. Finnell, Hongyan Wang Threshold for neural tube defect risk by accumulated singleton loss-of-function variants Cell Research 2018 28(10):1039-1041
Zhongzhong Chen, Lele Kuang, Richard H. Finnell, Hongyan Wang Genetic and functional analysis of SHROOM1-4 in a Chinese neural tube defect cohort Human Genetics 2018 137(3):195-202
Zhongzhong Chen, Yunping Lei, Xuanye Cao, Yufang Zheng, Fang Wang, Yihua Bao, Rui Peng, Richard H. Finnell, Ting Zhang, Hongyan Wang Genetic analysis of Wnt/PCP genes in neural tube defects BMC Med Genomics 2018 11(1):38
Xiaoling Lin*, Zhongzhong Chen* （共同第一作者）, Haitao Chen, Jun Qi, Fang Liu, Rong Na, Hongjie Yu, Rong Shi, Zengnan Mo, Yinghao Sun, Qiang Ding, Zhimei Gao, Haowen Jiang, Siqun Lilly Zheng, Jianfeng Xu TEX15: A DNA repair gene associated with prostate cancer risk in Han Chinese The Prostate 2017 77(12):1271-1278
Aleksandra Olow*, Zhongzhong Chen* （共同第一作者）, R. Hannes Niedner, Denise M. Wolf, Christina Yau, Aleksandr Pankov, Evelyn Pei Rong Lee, Lamorna Brown-Swigart, Laura J. van 't Veer, Jean-Philippe Coppe An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer Cancer Research 2016 76(7):1733-1745
Zhongzhong Chen （通讯作者）, Tianhong Zhang, Jun Lin, Zidan Yan, Yongren Wang, Weiqiang Zheng, Kevin C. Weng GeneSense: a new approach for human gene annotation integrated with protein-protein interaction networks Scientific Reports 2014 4:4474
Jue Ruan, Heng Li, Zhongzhong Chen, Avril Coghlan, ..., Jun Wang, Richard Durbin TreeFam: 2008 Update Nucleic Acids Research 2008 36: D735-D740