导师姓名： 于永春 专业代码： 100214
性别： 男 专业名称： 肿瘤学
培养单位： 附属胸科医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： **
邮编： 200030 邮箱地址： yyc@tongji.edu.cn

研究方向 (点击浏览详细信息)
肺癌分子发病机制及肿瘤标志物的筛选与验证

社会任职
农工党党员，农工党上海市委委员，上海申康委员会副主委

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 科罗索酸对糖尿病相关肝癌的抑制作用及其机制 国家自然科学基金 2018-01~2021-12 55万元 课题负责人
** Rig-I调控破骨细胞伪足体的形成促进破骨作用 国家自然科学基金 2015-01~2018-12 80万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Zhang C, Ma L, Niu Y, Wang Z, Xu X, Li Y, Yu Y （通讯作者） Circular RNA in Lung Cancer Research: Biogenesis, Functions, and Roles Int J Biol Sci 2020 2020 Jan 16;16(5):803-814
Xu X, Tao Y, Niu Y, Wang Z, Zhang C, Yu Y （通讯作者）, Ma L miR-125a-5p inhibits tumorigenesis in hepatocellular carcinoma Aging (Albany NY) 2019 2019 Sep 17;11(18):7639-7662
Chen R, Xu X, Qian Z, Zhang C, Niu Y, Wang Z, Sun J, Zhang X, Yu Y （通讯作者） The biological functions and clinical applications of exosomes in lung cancer Cell Mol Life Sci 2019 2019 Dec;76(23):4613-4633
Ma L, Jiang H, Xu X, Zhang C, Niu Y, Wang Z, Tao Y, Li Y, Cai F, Zhang X, Wang X, Yu Y （通讯作者） Tanshinone IIA mediates SMAD7-YAP interaction to inhibit liver cancer growth by inactivating the transforming growth factor beta signaling pathway Aging (Albany NY) 2019 2019 Nov 11;11(21):9719-9737
Chen R, Xu X, Tao Y, Qian Z, Yu Y （通讯作者） Exosomes in hepatocellular carcinoma: a new horizon Cell Commun Signal 2019 2019 Jan 7;17(1):1
Yang Z, Tao Y, Xu X, Cai F, Yu Y （通讯作者）, Ma L Bufalin inhibits cell proliferation and migration of hepatocellular carcinoma cells via APOBEC3F induced intestinal immune network for IgA production signaling pathway. Biochem Biophys Res Commun. 2018 10;503(3):2124-2131
Yuquan Tao, Liang Shan, Xin Xu, Hongyuan Jiang, Rui Chen, Zijun Qian, Zongguo Yang, Bin Liang,Haiyin Zheng, Feng Cai, Yongchun Yu （通讯作者）,Lifang Ma Huaier Augmented the Chemotherapeutic Sensitivity of Oxaliplatin via Downregulation of YAP in Hepatocellular Carcinoma. Journal of Cancer 2018 10;9(21):3962-3970
Zhang X, Xu Y, Qian Z, Zheng W, Wu Q, Chen Y, Zhu G, Liu Y, Bian Z, Xu W, Zhang Y, Sun F, Pan Q, Wang J, Du L, Yu Y. （通讯作者） circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death Dis. 2018 25;9(11):1091.
Xu X, Tao Y, Shan L, Chen R, Jiang H, Qian Z, Cai F, Ma L, Yu Y （通讯作者） The Role of MicroRNAs in Hepatocellular Carcinoma. Journal of Cancer 2018 8;9(19):3557-3569
Yanfeng Xu, Yinghui Zhao, Yanli Xu, Yu Guan, Xiao Zhangb, Yan Chen, Qi Wu, Guoqing Zhu, Yuxin Chen, Fenyong Sun, JiayiWang, Yongchun Yu. （通讯作者） Blocking inhibition to YAP by ActinomycinD enhances anti-tumor efficacy of Corosolic acid in treating liver cancer. Cell Signal 2017 29:209-217
Yang Z, Liao X, Lu Y, Xu Q, Tang B, Chen X, Yu Y. （通讯作者） Add-On Therapy with Traditional Chinese Medicine Improves Outcomes and Reduces Adverse Events in Hepatocellular Carcinoma: A Meta-Analysis of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2017 2017:**.
Yuquan Tao, Feng Cai, Liang Shan, Hongyuan Jiang, Lifang Ma, Yongchun Yu. （通讯作者） The Hippo signaling pathway: an emerging anti-cancer drug target. Discov Med. 2017 24(130):7-18.
LIANG SHAN, HONGYUAN JIANG, LIFANG MA, YONGCHUN YU. （通讯作者） Yes associated protein: A novel molecular target for the diagnosis, treatment and prognosis of hepatocellular carcinoma. ONCOLOGY LETTERS 2017 14（3）: 3291-3296
Yuquan Tao, Feng Cai, Liang Shan, Hongyuan Jiang, Lifang Ma, Yongchun Yu. （通讯作者） The Hippo signaling pathway: an emerging anti-cancer drug target. Discov Med. 2017 24(130):7-18.
Shan L, Li Y, Jiang H, Tao Y, Qian Z, Li L, Cai F, Ma L, Yu Y. （通讯作者） Huaier Restrains Proliferative and Migratory Potential of Hepatocellular Carcinoma Cells Partially Through Decreased Yes-Associated Protein 1 Journal of Cancer 2017 8(19):4087-4097
Zhen N, Yang Q, Wu Q, Zhu X, Wang Y, Sun F, Mei W, Yu Y. （通讯作者） A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells. Cancer Chemother Pharmacol. 2016 77(1):169-80.
Yulan Wang, Ran Cui, Xiao Zhang, Yongxia Qiao, Xiangfan Liu, Yefei Chang, Yongchun Yu （通讯作者）, Fenyong Sun, Jiayi Wang. SIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma. Oncotarget 2016 8;7(10):11284-98
Ni Zhen, Qingyuan Yang, Kangdi Zheng, Zeping Han, Fenyong Sun, Wenjie Mei, Yongchun Yu. （通讯作者） MiroRNA-127-3p targets XRCC3 to enhance the chemosensitivity ofesophageal cancer cells to a novel phenanthroline-dione derivative. Int J Biochem Cell Biol. 2016 79（2016）:158-167.
Hui Yu, Liyun Bai, Yaxian Zhang, Zhanli Wang, Yongchun Yu. （通讯作者） Repetitive extragenic palindromic DNA sequences from Brucella melitensis stimulate Toll-like receptor 9 signaling in macrophages. Mol Med Rep. 2016 15(1):271-276
Ma L, Ji L, Yu Y （通讯作者）, Wang J. Novel molecular targets for diagnosis and treatment of hepatocellular carcinoma. Discov Med. 2015 19(102):7-14.
Lifang Ma, Qiuhui Pan, Fenyong Sun, Yongchun Yu （通讯作者）, Jiayi Wang. Cluster of differentiation 166 (CD166) regulates cluster of differentiation (CD44) via NF-κB in liver cancer cell line Bel-7402. Biochem Biophys Res Commun. 2014 22;451(2):334-8
Yu W, Wang J, Ma L, Tang X, Qiao Y, Pan Q, Yu Y （通讯作者） CD166 plays a pro-carcinogenic role in liver cancer cells via inhibition of FOXO proteins through AKT. Oncol Rep. 2014 32(2):677-83
Yu H, Jin H, Sun L, Zhang L, Sun G, Wang Z, Yu Y. （通讯作者） Toll-like receptor 7 agonists: chemical feature based pharmacophore identification and molecular docking studies. PLoS One 2013 8(3):e56514.
Wang J, Ma L, Weng W, Qiao Y, Zhang Y, He J, Wang H, Xiao W, Li L, Chu Q, Pan Q, Yu Y （通讯作者）, Sun F. Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer. Hepatology 2013 58(3):1011-20