导师姓名： 方贻儒 专业代码： 100205
性别： 男 专业名称： 精神病与精神卫生学
培养单位： 附属精神卫生中心 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市 徐汇区 宛平南路600号yirufang@aliyun.com
邮编： 200030 邮箱地址： yirufang@aliyun.com

研究方向 (点击浏览详细信息)
心境障碍的基础与临床

社会任职
海峡两岸医药卫生交流协会精神卫生和精神病学专委会 常委
国家卫计委住院医生规范化培训规划教材《精神病学》 主编
中国神经科学学会精神病学基础与临床分会（CSNP） 主任委员
上海市“精品课程”教材《精神病学》 主编
上海市医师协会精神科医师分会 会长
中华医学会精神医学分会(CSP) 副主任委员
中国医师协会精神科医师分会 常委
中华精神科杂志 / 上海交大学报医学版 / 中国神经精神疾病杂志： 编委/副主编
J Affect Disord / N Bulletin / Intl J Bipolar Disord / Gen Psychiatry: Editor Member
中国双相障碍协作组 组长
国家自然基金委员会第14届专家评审组 二审专家
中国科学院脑与智能卓越创新中心 客座教授
上海市重性精神病重点实验室学术委员会 委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** PKC激活效应在抑郁症免疫炎症机制中的作用探究 国家自然科学基金委员会重点项目 2020-01~2024-12 297万元 课题负责人
CRC2018DSJ01-1 双相障碍与氧化应激损伤机制——基于机器学习的临床大数据分析 SMHC临床研究中心 2018-12~2019-11 20万元 课题负责人
CRC2018ZD02 中国汉族人群双相障碍家系队列遗传研究 SMHC临床研究中心 2018-12~2022-11 200万元 课题负责人
PRKCB1对免疫炎症因子的调控效应及其与抑郁障碍的关系探究 国家自然科学基金 2018-01~2021-12 54万元 课题负责人
2016YFC** 基于抑郁障碍临床病理特征的多维度诊断、个体化治疗及管理技术 科技部：国家重点研发计划，重大慢性非传染性疾病防控研究 2016-09~2020-12 566万元 课题负责人
SHDC** 心情温度计——心境障碍早期识别与治疗管理前沿技术的开发与应用 上海申康医院发展中心市级医院新兴前沿技术联合攻关项目 2016-01~2018-12 50万元 课题负责人
SHDC** 基于移动医疗平台的心境障碍综合防治模式研发与应用 上海申康医院发展中心慢性病综合防治项目 2015-12~2018-11 15万元 课题负责人
NO 上海市精神疾病临床医学中心 上海市卫计委 2014-01~2018-12 400万元 课题负责人
** TNF-α基因多态性调节抑郁障碍认知功能损害的脑网络机制研究 国家自然科学基金委员会“情感和记忆的神经环路基础”重大研究计划 2013-01~2015-12 70万元 课题负责人
2012BAI01B04 抑郁和焦虑障碍规范化干预技术的研发与优化研究 “十二五”国家科技支撑项目 2012-01~2014-12 283万元 课题负责人
2011-873 国家临床重点专科-上海市精神卫生中心 卫生部 2011-01~2013-12 1000万元 课题负责人
** miRNA调控通路在双相障碍病理机制中作用探究 国家自然科学基金委员会面上项目 2010-01~2012-12 30万元 课题负责人
沪交医科【2008】－6 临床精神病学 上海交通大学医学院“重点学科建设” 2008-01~2011-12 40万元 课题负责人
2006AA02Z430 亚综合征抑郁遗传与环境病因学探讨及评价指标体系构建 国家高技术研究发展计划（863计划） 2007-01~2008-12 90万元 课题负责人
难治性抑郁症的优化治疗方案研究 上海市科委“登山行动计划” 2006-01~2008-12 15万元 课题负责人
2004BA720A21-02 难治性抑郁症的临床特征及治疗方案优化研究 “十五”国家科技攻关项目, 科技部 2005-01~-2007-12 100万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Fang X, Zhang C, Wu Z, Peng D, Xia W, Xu J, Wang C, Cui L, Huang J, Fang Y* （通讯作者） The association between somatic symptoms and suicidal ideation in Chinese first-episode major depressive disorder J Affect Disord 2018 2018 Oct 17; 245:17-21. doi: 10.1016/j.jad.2018.10.110. [Epub ahead of print]
Mao R, Zhang C, Chen J, Zhao G, Zhou R, Wang F, Xu J, Yang T, Su Y, Huang J, Wu Z, Cao L, Wang Y, Hu Y, Yuan C, Yi Z, Hong W, Wang Z, Peng D, Fang Y* （通讯作者） Different levels of pro- and anti-inflammatory cytokines in patients with unipolar and bipolardepression J Affect Disord 2018 2018 Sep; 237: 65-72. doi: 10.1016/j.jad.2018.04.115.
Huang J, Wang Y, Chen J, Zhang Y, Yuan Z, Yue L, Haro JM, Moneta MV, Novick D, Fang Y* （通讯作者） Clinical outcomes of patients with major depressive disorder treated with either duloxetine, escitalopram, fluoxetine, paroxetine, or sertraline Neuropsychiatr Dis Treat 2018 2018 Sep 26; 14:2473-2484. doi: 10.2147/NDT.S159800. eCollection 2018.
Zhao D, Wu Z, Zhang H, Mellor D, Ding L, Wu H, Wu C, Huang J, Hong W, Peng D, Fang Y* （通讯作者） Somatic symptoms vary in major depressive disorder in China Compr Psychiatry 2018 2018 Nov; 87:32-37. doi: 10.1016/j.comppsych.2018.08.013. Epub 2018 Aug 28.
Yang T, Zhao G, Mao R, Huang J, Xu X, Su Y, Zhu N, Zhou R, Lin X, Xia W, Wang F, Liu R, Wang X, Huang Z, Wang Y, Hu Y, Cao L, Yuan C, Wang Z, Lam RW, Chen J, Fang Y* （通讯作者） The association of duration and severity of disease with executive function: Differences between drug-na?ve patients with bipolar and unipolar depression J Affect Disord 2018 2018 May 29; 238: 412-417. doi: 10.1016/j.jad.2018.05.051.
Geng R, Li Z, Yu S, Yuan C, Hong W, Wang Z, Wang Q, Yi Z, Fang Y* （通讯作者） Weighted gene co-expression network analysis identifies specific modules and hub genes related to subsyndromal symptomatic depression World J Biol Psychiatry 2018 2018 Nov 29:1-23. doi: 10.1080/**.2018.**. [Epub ahead of print]
Zhou R, Wang F, Zhao G, Xia W, Peng D, Mao R, Xu J, Wang Z, Hong W, Zhang C, Wang Y, Su Y, Huang J, Yang T, Wang J, Chen J, Palaniyappan L, Fang Y* （通讯作者） Effects of tumor necrosis factor-α polymorphism on the brain structural changes of the patientswith major depressive disorder Transl Psychiatry 2018 2018 Oct 11;8(1):217. doi: 10.1038/s41398-018-0256-x.
Fang X, Zhang C, Wu Z, Peng D, Xia W, Xu J, Wang C, Cui L, Huang J, Fang Y* （通讯作者） Prevalence, risk factors and clinical characteristics of suicidal ideation in Chinese patients with depression J Affect Disord 2018 2018 Aug 1; 235: 135-141. doi: 10.1016/j.jad.2018.04.027.
Wu Z, Cao L, Peng D, Mellor D, Zhang C, Li H, Wang Z, Song Y, Li C, Fang Y* （通讯作者） The clinical correlates of comorbid anxiety symptoms and syndromal anxiety in patients with major depressive disorder Psychiatry Res 2018 2018 Aug 28; 269: 251-257. doi: 10.1016/j.psychres. 2018.07.019. [Epub ahead of print]
Wang Z, Chen J, Yang H, Ma Y, Meron D, Liu T, Yu X, Fang Y* （通讯作者） Assessment and management of bipolar disorder: Principal summary of updated Chinese guidelines Bipolar Disord 2018 2018 May; 20(3): 289-292. doi: 10.1111/bdi.12646.
Huang J, Yuan CM, Xu XR, Wang Y, Hong W, Wang ZW, Su YS, Hu YY, Cao L, Wang Y, Chen J, Fang YR* （通讯作者） The relationship between lifestyle factors and clinical symptoms of bipolar disorder patients in a Chinese population Psychiatry Res 2018 2018 Aug; 266: 97-102. doi: 10.1016/j.psychres.2018.04.059.
Xia W, Zhou R, Zhao G, Wang F, Mao R, Peng D, Yang T, Wang Z, Chen J, Fang Y* （通讯作者） Abnormal whitematter integrity in Chinese young adults with first-episode medication-free anxious depression: a possible neurological biomarker of subtype major depressive disorder Neuropsychiatr Dis Treat 2018 2018 Aug 10; 14: 2017-2026. doi: 10.2147/NDT.S169583. eCollection 2018.
Chengqing Yang, Guoqin Hu, Zezhi Li, Qingzhong Wang, Xuemei Wang, Chengmei Yuan, Zuowei Wang, Wu Hong, Weihong Lu, Lan Cao1, Jun Chen, Yong Wang, Shunying Yu, Yimin Zhou （通讯作者）, Zhenghui Yi, Yiru Fang* Differential gene expression in patients with subsyndromal symptomatic depression and major depressive disorder PLOS ONE 2017 https://doi.org/10.1371/journal.pone.** March 23, 2017.
Hu Y, Hong W, Smith A, Yu S, Li Z, Wang D, Yuan C, Cao L, Wu Z, Huang J, Fralick D, Phillips MR, Fang Y* （通讯作者） Association analysis between mitogen-activated protein/extracellular signal-regulated kinase (MEK) gene polymorphisms and depressive disorder in the Han Chinese population J Affect Disord 2017 2017 Nov; 222: 120-125. doi: 10.1016/j.jad.2017.06.059.
Zezhi Li, Zuowei Wang, Chen Zhang,Jun Chen, Yousong Su, Jia Huang, Zhenghui Yi,Chengmei Yuan, Wu Hong, Yong Wang, Zhiguo Wu, Yingyan Hu, Lan Cao, Daihui Peng,Yangtai Guan, Yimin Zou, Shunying Yu, Donghong Cui, Yiru Fang* （通讯作者） Reduced ENA78 levels as novel biomarker for major depressive disorder and venlafaxine efficiency: Result from a prospective longitudinal study Psychoneuroendocrinology 2017 2017;81:113-121.
Chen Zhang,Dengfeng Zhang,Zhiguo Wu,Daihui Peng,Jun Chen,Jianliang Ni,Wenxin Tang,Lin Xu,Yonggang Yao,Yiru Fang （通讯作者） Complement factor H and susceptibility to majordepressive disorder in Han Chinese The British Journal of Psychiatry 2016 208（5）：446-452.doi: 10.1192/bjp.bp.115.163790.
GuoqingZhao,ChenZhang,JunChen,YousongSu,RubaiZhou,Fan Wang, Weiping Xia,Jia Huang,ZuoweiWan,YingyanHu,LanCao,Xiaoyun Guo, ChengmeiYuan,YongWang,ZhenghuiY,WeihongLu,YanWu,ZhiguoWu, Wu Hon,Daihui Peng,Yiru Fang （通讯作者） Ratio of mBDNF toproBDNF for Differential DiagnosisofMajor Depressive Disorder and Bipolar Depression molecular neurobiology 2016 54(7):5573–5582
Chen Zhang, Zuowei Wang, Wu Hong, Zhiguo Wu, Daihui Peng, Yiru Fang （通讯作者） ZNF804A Genetic Variation Confers Risk to Bipolar Disorder Molecular Neurobiology 2016 53(5):2936-2943 .DOI:10.1007/s12035-015-9193-3
Chen Zhang,Weihong Lu,Zuowei Wang,Jianliang Ni,Jiangtao Zhang,Wenxin Tang,Yiru Fang （通讯作者） A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese Translational Psychiatry 2016 6：e701. doi: 10.1038/tp.2015.199.
Daihui Peng, Ting Shen, Linda Byrne, Chen Zhang, Yueqi Huang, Xin Yu, Jingping Zhao, Marita McCabe, David Mellor, Yiru Fang （通讯作者） Atypical features and treatment choices in bipolar disorders: a result of the National Bipolar Mania Pathway Survey in China Neuroscience Bulletin 2015 01/2015; 31(1):22-30.DOI:10.1007/s12264-014-1487-3
Daihui Peng, Feng Shi, Gang Li, Drew Fralick, Ting Shen, Meihui Qiu, Jun Liu, Kaida Jiang, Dinggang Shen, Yiru Fang （通讯作者） Surface Vulnerability of Cerebral Cortex to Major Depressive Disorder PLoS ONE 2015 03/2015; 10(3):e**. DOI:10.1371/journal.pone.**
Haozhe Li, Wu Hong, Chen Zhang, Zhiguo Wu, Zuowei Wang, Chenmei Yuan, Zezhi Li, Jia Huang, Zhiguang Lin, Yiru Fang （通讯作者） IL-23 and TGF-β1 levels as potential predictive biomarkers in treatment of bipolar I disorder with acute manic episode Journal of Affective Disorders361-366. 2015 174:361-366
Zuowei Wang, Jun Chen, Chen Zhang, Keming Gao, Wu Hong, Mengjuan Xing, Zhiguo Wu, Chengmei Yuan, Jia Huang, Daihui Peng, Yong Wang, Weihong Lu, Zhenghui Yi, Xin Yu, Jingping Zhao, Yiru Fang （通讯作者） Guidelines concordance of maintenance treatment in euthymic patients with bipolar disorder: Data from the national bipolar mania pathway survey (BIPAS) in mainland China Journal of Affective Disorders 2015 04/2015; 182:101-105.DOI:10.1016/j.jad.2015.04.028
Chengmei Yuan, Jia Huang, Keming Gao, Zhiguo Wu, Jun Chen,Yong Wang, Wu Hong, Zhenghui Yi, Yingyan Hu, Lan Cao, Zezhi Li, Kareen K. Akiskal, Hagop S. Akiskal, Biao Wang, Yiru Fang （通讯作者） Validation of the Chinese Version of the Short TEMPS-A and its application in patients with mood disorders Journal of Affective Disorders. 01/2015; 170:178–184. 2015 170(1):178-184
Xiaoyun Guo,Zezhi LI,Chen Zhang,Zhenghui Yi,Haozhe LI,Lan Cao,Chengmei Yuan,Wu Hong,Zhiguo Wu,Daihui Peng,Jun Chen,Weiping Xia,Guoqing Zhao,Fan Wang,Shunying Yu,Donghong Cui,Yifeng Xu,Chowdhury M.I. Golam,Alicia K. Smith,Tong Wang,Yiru Fang （通讯作者） Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression Journal of Psychiatric Research 2015 69：1-6. doi: 10.1016/j.jpsychires.2015.07.011.
Daihui Peng, Elizabeth B. Liddle, Sarina J Iwabuchi, Chen Zhang, Zhiguo Wu, Jun Liu, Kaida Jiang, Lin Xu, Peter F Liddle, Lena Palaniyappan, Yiru Fang （通讯作者） Dissociated large-scale functional connectivity networks of the precuneus in medication-na?ve first-episode depression Psychiatry Research : Neuroimaging 2015 01/2015; 232(3):250-256. DOI:10.1016/j.pscychresns.2015.03.003
Chen Zhang, Yiru Fang （通讯作者）, Lin Xu Glutamate receptor 1 phosphorylation at serine 845 contributes to the therapeutic effect of olanzapine on schizophrenia-like cognitive impairments Schizophrenia Research 2014 07():054-
Yi Zhang, Meijuan Chen, Jun Chen, Zhiguo Wu, Shunying Yu, Yiru Fang （通讯作者）, Chen Zhang Metabolic syndrome in patients taking clozapine: prevalence and influence of catechol-O-methyltransferase genotype Psychopharmacology (Berl) 2014 231(10):2211-2218
Daihui Peng, Feng Shi, Ting Shen, Ziwen Peng, Chen Zhang, Xiaohua Liu, Meihui Qiu, Jun Liu, Kaida Jiang, Yiru Fang （通讯作者）, Dinggang Shen Altered brain network modules induce helplessness in major depressive disorder Journal of Affective Disorders 01/2014; 168:21–29 2014 168():21-29
Chen Zhang, Jiangtao Zhang, Juan Fan, Wenhong Cheng, Yasong Du, Shunying Yu, Yiru Fang （通讯作者） Identification of ANKK1 rs** variant in schizophrenia: New data and meta-analysis American Journal of Medical Genetics Part B Neuropsychiatric Genetics 2014 165(7):564-571
Wu Hong, Jinbo Fan, Chengmei Yuan, Chen Zhang, Yingyan Hu, Daihui Peng, Yong Wang, Jia Huang, Zezhi Li, Shunying Yu, Xiaohua Liu, Zhiguo Wu, Jun Chen, Zhenghui Yi, Lin Xu, Yiru Fang （通讯作者） Significantly decreased mRNA levels of BDNF and MEK1 genes in treatment-resistant depression Neuroreport 2014 25():753-755
Zuowei Wang, Keming Gao, Wu Hong, Mengjuan Xing, Zhiguo Wu, Jun Chen, Chen Zhang, Chengmei Yuan, Jia Huang, Daihui Peng, Yong Wang, Weihong Lu, Zhenghui Yi, Xin Yu, Jingping Zhao, Yiru Fang （通讯作者） Pharmacotherapy for acute mania and disconcordance with treatment guidelines: bipolar mania pathway survey (BIPAS) in mainland China BMC Psychiatry 2014 14(1):167-
Chen Zhang, Jun Cai, Jiangtao Zhang, Zezhi Li, Zhongwei Guo, Xu Zhang, Weihong Lu, Yi Zhang, Aihua Yuan, Shunying Yu, Yiru Fang （通讯作者） Genetic modulation of working memory deficits by ankyrin 3 gene in schizophrenia Prog Neuropsychopharmacol Biol Psychiatry 2014 50():110-115
Zuowei Wang, Keming Gao, Wu Hong, Mengjuan Xing, Zhiguo Wu, Jun Chen, Chen Zhang, Chengmei Yuan, Jia Huang, Daihui Peng, Yong Wang, Weihong Lu, Zhenghui Yi, Xin Yu, Jingping Zhao, Yiru Fang （通讯作者） Guidelines Disconcordance in Acute Bipolar Depression: Data from the National Bipolar Mania Pathway Survey (BIPAS) in Mainland China PLoS ONE 2014 9(4):-
Zuowei Wang, Chen Zhang, Jia Huang, Chengmei Yuan, Wu Hong, Jun Chen, Shunying Yu, Lin Xu, Keming Gao, Yiru Fang （通讯作者） MiRNA-206 and BDNF genes interacted in bipolar I disorder Journal of Affective Disorders 2014 162():116-119
Zuowei Wang, Zezhi Li, Keming Gao, Yiru Fang （通讯作者） Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis BMC Psychiatry (Impact Factor: 2.24). 12/2014; 14(1):5. 2014 14(1):5-
Chen Zhang, Zezhi Li, Zhiguo Wu, Jun Chen, Zuowei Wang, Daihui Peng, Wu Hong, Chengmei Yuan, Zhen Wang, Shunying Yu, Yifeng Xu, Lin Xu, Zeping Xiao, Yiru Fang （通讯作者） A study of N-methyl-D-aspartate receptor gene (GRIN2B) variants as predictors of treatment-resistant major depression Psychopharmacology (Berl) 2014 231(4):685-693
Chen Zhang, Zhiguo Wu, Wu Hong, Zuowei Wang, Daihui Peng, Jun Chen, Chengmei Yuan, Shunying Yu, Lin Xu, Yiru Fang （通讯作者） Influence of BCL2 gene in major depression susceptibility and antidepressant treatment outcome J Affect Disord 2014 155():288-294
Zezhi Li, Chen Zhang, Jinbo Fan, Chengmei Yuan, Jia Huang, Jun Chen, Zhenghui Yi, Zuowei Wang, Wu Hong, Yong Wang, Weihong Lu, Yangtai Guan, Zhiguo Wu, Yousong Su, Lan Cao, Yingyan Hu, Yong Hao, Mingyuan Liu, Shunying Yu, Donghong Cui, Lin Xu, Yanyan Song, Yiru Fang （通讯作者） Brain-derived neurotrophic factor levels and bipolar disorder in patients in their first depressive episode: 3-year prospective longitudinal study Br J Psychiatry 2014 205(1):29-35
Cai J, Yi Z, Lu W （通讯作者）, Fang Y, Zhang C. Crosstalk between 5-HT2cR and PTEN signaling pathway in atypical antipsychotic-induced metabolic syndrome and cognitive dysfunction Med Hypotheses 2013 80(4):486-489
Zhiguo Wu, Jun Chen, Chengmei Yuan, Wu Hong, Daihui Peng, Chen Zhang, Lan Cao, Yiru Fang （通讯作者） Difference in remission in a Chinese population with anxious versus nonanxious treatment-resistant depression: A report of OPERATION study J Affect Disord 2013 150(3):834-839
Lu W, Wu H, Cai J, Wang Z, Yi Z, Yu S, Fang Y （通讯作者）, Zhang C. Lack of association of SLC1A1 variants with schizophrenia in Chinese Han population Psychiatry Research 2013 210(2):669-671
Li Z, Qi D, Chen J, Zhang C, Yi Z, Yuan C, Wang Z, Hong W, Yu S, Cui D, Fang Y. （通讯作者） Venlafaxine inhibits the upregulation of plasma tumor necrosis factor-alpha (TNF-α) in the Chinese patients with major depressive disorder: a prospective longitudinal study Psychoneuroendocrinology 2013 38(1):107-114
Xu Zhang, Chen Zhang, Zhiguo Wu, Zuowei Wang, Daihui Peng, Jun Chen, Wu Hong, Chengmei Yuan, Zezhi Li, Shunying Yu, Yiru Fang （通讯作者） Association of genetic variation in CACNA1C with bipolar disorder in Han Chinese Journal of Affective Disorders 2013 150():261-265
Yi Zhang, Meijuan Chen, Zhiguo Wu, Jun Chen, Shunying Yu, Yiru Fang （通讯作者）, Chen Zhang Association Study of Val66Met Polymorphism in Brain-Derived Neurotrophic Factor Gene with Clozapine-Induced Metabolic Syndrome: Preliminary Results PLoS ONE 01/2013; 8(8):e72652 2013 8(8):-
Zuowei Wang, Jinbo Fan, Keming Gao, Zezhi Li, Zhenghui Yi, Lingxiao Wang, Jia Huang, Chengmei Yuan, Wu Hong, Shunying Yu, Yiru Fang （通讯作者） Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) Gene Associated with Treatment Response to Mood Stabilizers in Patients with Bipolar I Disorder J Mol Neurosci 2013 50(2):305-310
Zezhi Li, Yanxia Zhang, Zuowei Wang, Jun Chen, Jinbo Fan, Yangtai Guan, Chen Zhang, Chengmei Yuan, Wu Hong, Yong Wang, Zhiguo Wu, Jia Huang, Yingyan Hu, Lan Cao, Zhenghui Yi, Donghong Cui, Shunying Yu, Yiru Fang （通讯作者） The role of BDNF, NTRK2 gene and their interaction in development of treatment-resistant depression: Data from multicenter, prospective, longitudinal clinic practice J Psychiatr Res 2013 47(1):8-14
Jun Cai, Wen Zhang, Zhenghui Yi, Weihong Lu, Zhiguo Wu, Jun Chen, Shunying Yu, Yiru Fang （通讯作者）, Chen Zhang Influence of polymorphisms in genes SLC1A1, GRIN2B, and GRIK2 on clozapine-induced obsessive-compulsive symptoms Psychopharmacology (Berl) 2013 230(1):49-55
Wang T, Xiao S, Li X, Ding B, Ling H, Chen K, Fang Y （通讯作者） Using proton magnetic resonance spectroscopy to identify mild cognitive impairment Int Psychogeriatr 2012 24(1):19-27
Wang L, Peng D, Xie B, Jiang K, Fang Y （通讯作者） The extracellular signal-regulated kinase pathway may play an important role in mediating antidepressant-stimulated hippocampus neurogenesis in depression Medical Hypotheses 2012 79(1):87-91.
Wang Z, Li Z, Chen J, Huang J, Yuan C, Hong W, Yu S, Fang Y （通讯作者） Association of BDNF gene polymorphism with bipolar disorders in Han Chinese population Genes Brain Behav 2012 11(5):524-528
Peng DH, Shen T, Zhang J, Huang J, Liu J, Liu SY, Jiang KD, Xu YF, Fang YR. （通讯作者） Abnormal functional connectivity with mood regulating circuit in unmedicated individual with major depression: a resting-state functional magnetic resonance study Chin Med J (Engl) 2012 125(20):3701-06
Lu W, Zhang C, Yi Z, Li Z, Wu Z, Fang Y （通讯作者） Association between BDNF Val66Met polymorphism and cognitive performance in antipsychotic-na?ve patients with schizophrenia Journal of Molecular Neuroscience 2012 47(3):505-10.
Yi Z, Li Z, Yu S, Yuan C, Hong W, Wang Z, Cui J, Shi T, Fang Y （通讯作者） Blood-Based Gene Expression Profiles Models for Classification of Subsyndromal Symptomatic Depression and Major Depressive Disorder PLoS ONE 2012 7(2):e31283
Wang T, Xiao S, Li X, Wang H, Liu Y, Su N, Fang Y （通讯作者） Reliability and validity of the Chinese version of the neuropsychiatric inventory in mainland China Int J Geriatr Psychiatry 2012 27(5):539-44
Peng DH, Shen T, Zhang J, Huang J, Liu J, Liu SY, Jiang KD, Xu YF, Fang YR （通讯作者） Abnormal functional connectivity with mood regulating circuit in unmedicated individual with major depression: a resting-state functional magnetic resonance study Chin Med J (Engl) 2012 125(20):3701-3706
Wang Z, Li Z, Chen J, Huang J, Yuan C, Hong W, Yu S, Fang Y （通讯作者） Association of BDNF gene polymorphism with bipolar disorders in han chinese population Genes Brain and Behavior 2012 11(5):524-8.
Yi Z, Zhang C, Lu W, Song L, Liu D, Xu Y, Fang Y （通讯作者） Common variants in the TPH2 promoter confer susceptibility to paranoid schizophrenia Journal of Molecular Neuroscience 2012 47(3):465-9.
Fang Y （通讯作者）, Yuan C, Xu Y, Chen J, Wu Z, Cao L, Yi Z, Hong W, Wang Y, Jiang K, Cui X, Calabrese JR, Gao K; OPERATION StudyTeam A pilot study of the efficacy and safety of paroxetine augmented with risperidone, valproate, buspirone, trazodone, or thyroid hormone in adult Chinese patients with treatment-resistant major depression Journal of clinical psychopharmacology 2011 31(5):638-42.
Yuan C, Wang Z, Inslicht SS, McCaslin SE, Metzler TJ, Henn-Haase C, Apfel BA, Tong H, Neylan TC, Fang Y （通讯作者）, Marmar CR Protective factors for posttraumatic stress disorder symptoms in a prospective study of police officers Psychiatry Res 2011 188(1):45-50
Zhang C, Li Z, Shao Y, Xie B, Du Y, Fang Y （通讯作者）, Yu S Association study of tryptophan hydroxylase-2 Gene in schizophrenia and its clinical features in Chinese han population J Mol Neurosci 2011 43(3):406-11
Chen J, Muzina DJ, Kemp DE, Conroy C, Chan P, Serrano MB, Ganocy SJ, Fang Y （通讯作者）, Calabrese JR, Gao K Safety and efficacy of olanzapine monotherapy in treatment-resistant bipolar mania: a 12-week open-label study Human Psychopharmacology Clinical and Experimental 2011 26(8):588-95
Peng DH, Jiang KD, Fang YR （通讯作者）, Xu YF, Shen T, Long XY, Liu J, Zang YF Decreased regional homogeneity in major depression as revealed by resting-state functional magnetic resonance imaging Chinese Medical Journal 2011 124(3):369-373
Wang Z, Kemp DE, Chan PK, Fang Y , Ganocy SJ （通讯作者）, Calabrese JR, Gao K Comparisons of the Tolerability and Sensitivity of Quetiapine-XR in the Acute Treatment of Schizophrenia, Bipolar Mania, Bipolar Depression, Major Depressive Disorder, and Generalized Anxiety Disorder The International Journal of Neuropsychopharmacology 2011 14(1):131-142.
Wang Z, Gao K, Kemp DE, Chan PK, Serrano MB, Conroy C, Fang Y （通讯作者）, Ganocy SJ, Findling RL, Calabrese JR Lamotrigine Adjunctive Therapy to Lithium and Divalproex in Depressed Patients with Rapid Cycling Bipolar Disorder and a Recent Substance Use Disorder: A 12-week, Double-Blind, Placebo-Controlled Pilot Study Psychopharmacol Bull 2010 43(4):5-21
Zhang C, Xie B, Du Y, Cheng W, Fang Y （通讯作者）, Yu S Further evidence that methylenetetrahydrofolate reductase A1298C polymorphism is a risk factor for schizophrenia J Neural Transm 2010 117:1115-1117
Chen J, Fang Y （通讯作者）, Kemp DE, Calabrese JR, Gao K Switching to hypomania and mania: differential neurochemical, neuropsychological, and pharmacologic triggers and their mechanisms Curr Psychiatry Rep 2010 12:512-521
Fang Y （通讯作者）, Yuan C, Xu Y, Chen J, Wu Z, Cao L, Yi Z, Hong W, Wang Y, Jiang K, Gao K, Cui X, Nierenberg AA; OPERATION Study Team Comparisons of the Efficacy and Tolerability of Venlafaxine-XR, Mirtazepine, and Paroxetine in Treatment-Resistant Depression: a Double-blind, Randomized Pilot Study in a Chinese Population Journal of Clinical Psychopharmacology 2010 30(4):357-364