1、Fan XL, Luo GR, Yang DH, Ming M, Liu HM, Pu P, Le W#. Critical role of lysosome and its associated protein cathepsin D in manganese-induced toxicity in cultured midbrain astrocyte. Neurochemistry International,2010;56(2:) 291-300 2、Fan X, Luo G, Ming M, Pu P, Li L, Yang D, Le W. #. Nurr1 expression and its modulation in microglia.. Neuroimmunomodulation,2009;16(3):162-70 3、Ming Ming, Li X, Fan X, Yang D, Li L, Chen S, Gu Q , Le W#. Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease.. J Transl Med,2009;7:53-62 4、Li L, Zhang X, Yang D, Luo G, Chen S, Le W#. Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP.. Neurobiol Aging,2009;30:1091-1098 5、Du Y, Yang D, Li L, Luo G, Li T, Fan X, Wang Q, Zhang X, Wang Y, Le W#. P53-mediated autophagy induction prevents toxicity mediated by proteasome inhibition in primary dopamine neurons.. Autophagy,2009;5:1-13 6、 Le W*, Chen S. Biology of NR4A subfamily. The Encyclopedia of Movement Disorders,2009;495:1-4 7、Yang DH, Peng CG, Li L, Fan XL, Le W#. Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures.. J Neurosci Res.,2009;86:3393-3400 8、Pu P, Le W#. Dopamine neuron degeneration induced by MPP+ is independent of CED-4 pathway in Caenorhabditis elegans.. Cell Res,2008;18:978-81 9、Luo GR, Chen Y, Li XP, Liu TX, Le W#. Nr4a2 is essential for the differentiation of dopaminergic neurons during zebrafish embryogenesis.. Mol Cell Neurosci.,2008;9:202-210 10、Li XP, Du YL, Fan XL, Yang DH, Luo GR, Le W.#. c-Jun N-Terminal Kinase Mediates Lactacystin-Induced Dopamine Neuron Degeneration.. J Neuropathol Exp Neurol.,2008; 67:933-944 11、Chen S, Zhang XJ, Yang D, Du Y, Li L, Li X, Ming M, Le W#. D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways.. FEBS Letters,2008;582: 603-610 12、Zhang XJ, Chen S, Li L, Wang Q, Le W#. Folic acid protects motor neurons against the increased homocysteine, inflammation and apoptosis in SOD1G93A transgenic mice.. Neuropharmacology,2008;54:1112-1119 13、Le W*, Pan T, Huang M, Xu P, Xie W, Zhu W, Zhang X, Deng H, Jankovic J.. Decreased NURR1 gene expression in patients with Parkinson's disease. . J Neurol Sci.,2008;273:29-33 14、Li L, Zhong X, Le W#. Altered macrpautophagy in the spinal cord of SOD1 mutant mice. Autophagy.,2008;4: 1-4 15、Du Y, Li X, Yang D, Zhang X, Chen S, Huang K, Le W.#. Multiple molecular pathways are involved in the neuroprotection of GDNF against proteasome inhibitor induced dopamine neuron degeneration in vivo. J Exp BioMed.,2008;233:881-890 16、Pérez-Bello D, Xu ZH, Higginson-Clarke D, Rojas AM, Le W#. DNA-labelled cytidine assay for the quantification of CAG repeats.. J Neurosci Methods.,2008;169:201-7 17、Pan T, Zhu W, Zhao HR, Xie WJ, Jankovic J, Le W#. Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement. . J Neurobiol. Dis.,2008;32:16-25. 18、Zhu W, Xie W, Pan T, Jankovic J, Li J, Youdim MB, Le W#. Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration . J Neurochem.,2008;105:1970-8. 19、Pan T, Zhu W, Zhao HR, Xie WJ, Jankovic J, Le W#. Nurr1 deficiency predisposes lactacystin-induced dopamine neuron degeneration in vitro and in vivo. Brain Res.,2008;1222:222-229
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