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上海交通大学医学院研究生导师简介 卫立辛

上海交通大学 免费考研网/2013-01-10

基本信息
导师姓名: 卫立辛 专业代码: 071009
性别: 专业名称: 细胞生物学
培养单位: 健康科学研究所 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: lixinwei@yahoo.com weilixin@yahoo.com 上海市重庆南路225号健康科学研究所(200025)
研究方向 (点击浏览详细信息)
干细胞在肿瘤发生、发展过程中的作用
社会任职
第二军医大学附属第三医院肿瘤免疫与基因治疗研究中心 主任, 支部书记
全军肿瘤学专业委员会 委员
全军航天医学专业委员会 委员
第二军医大学学报编辑委员会 委员
中国肿瘤临床编辑委员会 委员
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
81030041自噬在肿瘤微环境条件下对肝癌转移复发的作用及其机制研究国家自然科学基金重点项目2011-01~~-2014-12240万元课题负责人
2010CB945600组织干细胞的干性维持、分化控制和免疫调节研究国家重点基础研究发展计划(973计划)项目2010-06~~-2011-121000万元课题参与人
学术论文 (#为通讯作者,*为共同第一作者)

1、Zhang C, Xu Y, Zhao J, Fan L, Jiang G, Li R, Ling Y, Wu M, Wei L. Elevated Expression of the Stem Cell Marker CD133 Associated with Line-1 Demethylation in Hepatocellular Carcinoma. Oncol. Ann Surg,2011;
2、Li Fuming, Liu Pingyu, Liu Changcheng, Xiang Dao, Deng Li, Li Wenlin, Kirk J. Wangensteen, Song Jianguo, Ma Yue, Hui Lijian, Wei Lixin, Li Lingsong, Ding Xiaoyan, Hu Yiping, He Zhiying, Wang Xin. Hepatoblast-like progenitor cells derived from embryonic stem cells can repopulate livers of mice. Gastroenterology,2010;
3、Zhipeng Han, Zhiqiang Tian, Gang Lv, Li Zhang, Guocheng Jiang, Kai Sun, Chenyang Wang, Xinxin Bu, Rong Li, Yufang Shi, Mengchao Wu and Lixin Wei*. Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favors the growth of B16 melanoma cells. Journal of cellular and molecular medicine,2010;
4、Jianrui Song, Zengqiang Qu, Xianling Guo, Qiudong Zhao, Xue Zhao, Lu Gao, Kai Sun, Feng Shen, Mengchao Wu, Lixin Wei*. Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells. Autophagy,2009;
5、Xianling Guo,,Nannan Ma,Jin Wang, Jianrui Song,Xinxin Bu,Yue Cheng, Kai Sun,Haiyan Xiong, Guocheng Jiang, Baihe Zhang,Mengchao Wu, Lixin Wei. Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells. BMC Cancer,2008;
6、Zhang C, Guo X, Jiang G, Zhang L, Yang Y, Shen F, Wu M, Wei L. CpG island methylator phenotype association with upregulated telomerase activity in hepatocellular carcinoma. Int J Cancer,2008;123(5):998-1004
7、Xinxin Bu, Chen Le, Fengqi Jia, Xianling Guo, Li Zhang, Mengchao Wu and Lixin Wei. Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells. Cancer Biology & Therapy,2008;
8、Guo X, Wang W, Zhou F, Lu Z, Fang R, Jia F, Bu X, Li R, Zhang B, Wu M, Wei L. siRNA-mediated inhibition of hTERT enhances chemosensitivity of hepatocellular carcinoma. Cancer Biol Ther,2008;
9、Xinxin Bu, Fengqi Jia, Weifeng Wang, Xianling Guo, Mengchao Wu and Lixin Wei. Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma Cells. BMC Cancer,2007;
10、Changsong Zhang, Zhengyou Li, Yue Cheng, FengqiJia, Rong Li, Mengchao Wu, Ke Li, and Lixin Wei. CpG island methylator phenotype association with elevated serum alpha-fetoprotein level in hepatocellular carcinoma. Clin Cancer Res,2007;
11、Li J, Song L, Zhang D, Wei L. Huang C. Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells. Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells. J Cell Biochem,2006;
12、Wang J, Ouyang W, Li J, Wei L, Ma Q, Zhang Z, Tong Q, He J, Huang C.. Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor κB induced by UV radiation. Cancer Res.,2005;
13、Wei L*, Yun-bo Shi. Matrix metalloproteinase stromelysin-3 in development and pathogenesis. Histology and histopathology,2005;
14、Wei L*, Jiannian Zhou, Arthur I. Roberts, and Yufang Shi. Lymphocyte reduction induced by hindlimb unloading: Distinct mechanisms in the spleen and thymus. Cell Research,2003;
15、JC Solomon, K Sharma, Wei L, T Fujita and YF Shi. A novel role for sphingolipid intermediates in activation-induced cell death in T cells. Cell Death and Differentiation,2003;
16、Zhao Jian, Wang Hao, Wei L, Nagy A. Habib,Xin Lu, Mengchao Wu,Yajun Guo. The cytotoxic effect of E1B55-kDa mutant adenovirus on human hepatocellular carcinoma cell lines. Cancer gene therapy,2001;


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