1、Du W, Hong J, Wang YC, Zhang YJ, Wang P, Su WY, Lin YW, Lu R, Zou W, Xiong H, Fang JY.#. MicroRNA 345, a methylation-sensitive Inhibition of JAK2/STAT3 signaling induces colorectal cancer cell apoptosis via mitochondrial pathway.. J Cell Mol Med,2012;16(8):1878-88 2、Su WY, Li JT, Cui Y, Hong J, Du W, Wang YC, Lin YW, Xiong H, Wang JL, Kong X, Gao QY, Wei LP, Fang JY#. Bidirectional regulation between WDR83 and its natural antisense transcript DHPS in gastric cancer. . Cell Res,2012;doi:10.1038/cr.2012.57 3、Xiong H, Hong J, Du W, Lin YW, Ren LL, Wang YC, Su, Wang JL, Cui Y, Wang ZH, Fang JY#. Roles of STAT3 and ZEB1 in E-cadherin downregulation and human colorectal cancer epithelial-mesenchymal transition. J Biol Chem.,2012;287(8):5819-32 4、Xiong H, Du W, Wang JL, Wang YC, Hong J, Fang JY#. Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer.. J Mol Med,2012;DOI 10.1007/s00109-012-0869-0 5、Du W, Wang YC, Su WY, Lin YW, Hong J, Lu R, Xiong H, Fang JY #. STAT5 isoforms play important role in colorectal cancer preferentially associated with STAT5b. . J Cell Physiol.,2012;227(6):2421-9 6、Weng YR, Cui Y, Fang JY #. Biological Functions of Cytokeratin 18 in Cancer.. Mol Cancer Res,2012;doi: 10.1158/1541-7786. MCR-11-0222 7、Wang P, Wang YC, Chen XY, Shen ZY, Cao H, Zhang YJ, Yu J,Zhu JD, Lu YY, Fang JY #. CTHRC1 is upregulated by promoter demethylation and TGF-β1 and may associated with metastasis in human gastric cancer. . Cancer Sci,2012;PMID:22590977 8、Xiong H, Du W, Zhang YJ, Hong J, Su WY, Tang JT, Wang YC, Lu R, Fang JY #. Trichostatin A, a histone deacetylase inhibitor, suppresses JAK2/STAT3 signaling via inducing the promoter-associated histone acetylation of SOCS1 and SOCS3 in human colorectal cancer cells. . Mol Carcinog,2012;51(2):174-84 9、Chooi EYH, Chen HM, Shen L, Miao Q, Weng YR, Chen XY, Ge ZZ, Xiao SD, Fang JY#. Chronic atrophy gastritis is a progressive disease: An Analysis Reports in Shanghai, China from 1985 – 2009. Singapore Medical Journal,2012;53(5):318-24 10、Kong X, Wang JL, Chen HM, Fang JY#. Comparison of the clinicopathological characteristics of young and elderly patients with gastric carcinoma: a meta-analysis. J Surg Oncol,2012;106:346–352 11、Gao QY, Wang ZH, Hao EY, Chui Y, Hu Y, Yang CQ, Liu F, Zheng P, Wang CD, Song YY, Fang JY#. A novel model might predict the risk of chronic atrophic gastritis: a multicenter prospective study in China. Scand J Gastroenterol,2012;47(5):509-17 12、Wang ZH, Gao QY, Fang JY#. Loss of PTEN expression as a predictor for resistance to anti-EGFR monoclonal therapy in metastatic colorectal cancer: Evidence from retrospective studies. Cancer Chemotherapy and Pharmacology,2012;69(6):1647-55 13、Wang ZH, Gao QY, Fang JY#. Repeat screening colonoscopy every 10 years or single colonoscopy for colorectal neoplasm screening in average-risk Chinese: A cost-effectiveness analysis. Asian Pacific J Cancer Prev,2012;13: 1761-6 14、Fu L, Chen L, Yang J, Ye T, Chen Y, Fang JY. HIF-1α-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism. Carcinogenesis,2012;33: 1664-1673 15、Wang ZH, Gao QY, Fang JY#. Meta-analysis of the efficacy and safety of Lactobacillus and Bifidobacterium containing probiotic compound preparation in Helicobacter pylori eradication therapy. J Clin Gastroenterol,2012;PMID:23090045 16、Wang ZH, Gao QY, Fang JY#. Green tea and incidence of colorectal cancer: evidence from prospective cohort studies. Nutr and Cancer,2012;64(8):1143-1152 17、Du W, Wang S, Zhou Q, Li X, Chu J, Chang Z, Tao Q, Ng E, Fang JY#, Sung JJY, Yu J. ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer. Oncogene,2012;PMID: 22907434 18、Xue H, Wang YC, Lin B, An J, Chen L, Chen J, Fang JY#. A meta-analysis of interleukin-10 -592 promoter polymorphism associated with gastric cancer risk. PLoS One. .,2012;7(7):e39868 19、Tang JT, Wang JL, Hong J, Du W, Zhao SL, Wang YC, Xiong H, Chen HM, Fang JY#. MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer.. Carcinogenesis,2011; 32(8):1207-15 20、Wang JL, Lin YW, Chen HM, Kong X, Hong J, Fang JY#. Calcium prevents tumorigenesis in a mouse model of colorectal cancer. . PLoS One,2011;6(8):2256634 21、Zhao SL, Hong J, Xie ZQ, Tang JT, Su WY, Du W, Chen YX, Lu R, Sun DF, Fang JY#. TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells.. PLoS One,2011;6(8):e23262 22、Cui Y, Su WY, Xing J, Wang YC, Wang P, Chen XY, Shen ZY, Cao H, Lu YY, Fang JY #. MiR-29a inhibits cell proliferation and induces cell cycle arrest through the downregulation of p42.3 in human gastric cancer.. PLoS One,2011; 6(10):e25872 23、Lin YW, Chen HM, Fang JY #. Concise review in gene silencing by polycomb group protein system and connections to cancers.. Cancer Invest.,2011;29(3):187-95 24、Ge ZZ, Chen HM, Gao YJ, Liu WZ, Xu CH, Tan HH, Chen HY, Wei W, Fang JY, Xiao SD. . Efficacy of Thalidomide for Refractory Gastrointestinal Bleeding from Vascular Malformation. . Gastroenterology.,2011;141(5):1629-1637 25、Kryczek I, Wu K, Zhao E, Wei S, Vatan L, Szeliga W, Huang E, Greenson J, Chang A, Rolinski J, Radwan P, Fang J, Wang G, Zou W. . IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer.. J Immunol,2011;186(7):4388-95 26、Wilke CM, Wang L, Wei S, Kryczek I, Huang E, Kao J, Lin Y, Fang JY#, Zou W . Endogenous interleukin-10 constrains Th17 cells in patients with inflammatory bowel disease. . J Transl Med.,2011;9(1):217 27、Lin YW, Wang JL, Chen HM, Zhang YJ, Lu R, Ren LL, Hong J, Fang JY#. Folic Acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile. Exp Clin Cancer Res.,2011;2011;30(1):116-7 28、Cui Y, Xue H, Lin B, Ni P, Fang JY#. A Meta-Analysis of CDH1 C-160A Genetic Polymorphism and Gastric Cancer Risk.. DNA Cell Biol,2011;30(11):937-45 29、Wang JL, Sun TT, Lin YW, Lu R, Fang JY#. Methodological reporting of randomized controlled trials in major hepato-gastroenterology journals in 2008 and 1998: a comparative study. BMC Med Res Methodol,2011;11(1):110-17 30、Sun TT, Wang JL, Fang JY#. Quality of RCTs exploring Helicobacter pylori eradication for the prevention of gastric cancer and preneoplastic lesions. Expert Rev Anticancer Ther,2011;11(10):1509-19 31、Lin YW, Wang JL, Chen HM, Zhang YJ, Lu R, Ren LL, Hong J, Fang JY #. Folic Acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile. J Exp Clin Cancer Res,2011;30(1):116-23 32、Ren LL, Fang JY#. Should we sound the alarm? Dysplasia and colitis-associated colorectal cancer. Asian Pac J Cancer Prev,2011;12(8):1881-6 33、Su WY, Xiong H, Fang JY #. Natural antisense transcripts regulate gene expression in an epigenetic manner.. Biochem Biophys Res Commun.,2010;396(2):177-81 34、Du W, Li WY, Lu R, Fang JY#. Folate and fiber in the prevention Between shadows and the light. World J Gastroenterol,2010;16(8):921-926 35、Tang JT, Wang JL, Fang JY#. Meta-analysis: Perioperative regional liver chemotherapy for improving survival and preventing liver metastases in patients with colorectal carcinoma. J Dig Dis,2010;11(4):208-14 36、Wang P, Tang JT, Peng YS, Chen XY, Zhang YJ, Fang JY#. XRCC1 down-regulated through promoter hypermethylation is involved in human gastric carcingenesis. J Dig Dis,2010;11(6):343-51 37、Wang X, Sun DF, Lu R, Chen ZF, Chen YX, Fang JY#. RAF may induce cell proliferation through hypermethylation of tumor suppressor genes promoter in gastric epithelial cells.. Cancer Sci,2009;100(1):117-25 38、Xiong H, Zhang ZG, Liang QC, Tian XQ, Sun DF, Chen YX, Fang JY. #. Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells. . Lab Invest,2009;89(6):717-725 39、Xiong H, Chen ZF, Liang QC, Du W, Chen HM, Su WY, Han ZG, Chen GQ, Fang JY.#. Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signaling.. J Cell Mol Med,2009;13(9B):3668-79 40、Zhang YJ, Dai Q, Tian XQ, Xiong H, Gao FH, Sun DF, Xu MH, Chen GQc, Han ZG, Fang JY#. mTOR Signal Pathway is a Target for the Treatment of Colorectal Cancer. . Annals of Surgical Oncology,2009;16:2617-28 41、Boccia S, Hung R, Ricciardi G, Gianfagna F, Ebert MP, Fang JY, Gao CM, G?tze T, Graziano F, Lacasa?a-Navarro M, Lin D, López-Carrillo L, Qiao YL, Shen H, Stolzenberg-Solomon R, Takezaki T, Weng YR, Zhang FF, van Duijn CM, Boffetta P, Taioli E.. Meta- and pooled analyses of the Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a HuGE-GSEC review. Am J Epid,2008;167(5):505-16 42、Xiong H, Zhang ZG, Tian XQ, Sun DF, Zhang YJ, Lu R, Liang QC, Chen YX, Fang JY. #. Inhibition of JAK1, JAK2 and STAT3 signaling induces apoptosis, cell cycle arrest and reduces tumor cell invasion in colorectal cancer cells. . Neoplasia,2008;10(3):287-97 43、Lu R, Wang X, Sun DF, Tian XQ, Zhao SL, Chen YX, Fang JY. #. Folic acid and sodium butyrate prevent tumorigenesis in a mouse model of colorectal cancer.. Epigenetics,2008;3(6):330-335 44、Gorelik G, Fang JY, Wu A, Sawalha AH, Richardson BC. Impaired T Cell Protein Kinase C{delta} Activation Decreases ERK Pathway Signaling in Idiopathic and Hydralazine-Induced Lupus.. J Immunol.,2007;179(8):5553-63 45、Lu R, Wang X, Chen ZF, Sun DF, Tian XQ, Fang JY#. Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decrease DNA methylation in colon cancer cells. . J Biol Chem,2007;282(16):12249-12259 46、Fang JY#, Lu R, Mikovits JA, Cheng ZH, Zhu HY, Chen YX,Lu LG. Recombinant DNA methyltransferase 1 constructs regulate expression of hMSH2 and hMLH1 in human colon cancer cell line SW1116. . Cancer Lett,2006;233(1):217-25 47、Fang JY#, Richardson BC. The MAPK signaling pathway and human colorectal cancer. . Lancet Oncology,2005;6(5):322-327 48、Fang JY#, Chen YX, Lu J, Lu R, Yang L, Zhu HY, Gu WQ, Lu LG. . Epigenetic modification regulates expression of tumor-associated genes and cell cycle in human colon cancer cell lines Colo-320 and SW1116.. Cell Res.,2004;13 (3):217-226 49、Flynn J,Fang JY,Mikovits JA, Reich NO.. A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase.. J Biol Chem.,2003;278(10): 8238-8243 50、Fang JY, Mikovits JA, Bagni R, Petrow-Sadowski CL, Ruscetti FW.. Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation.. J Virol.,2001;75(20):9753-61
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