1、Zhu S, Pan W, Song X, Liu Y, Tang Y, Wang H, Liu W, Shi Y, He D, Harley JB, Shen N#, Qian Y 2012, . A Novel Vector-Based Method for MiR-23b suppresses IL-17 associated autoimmune pathogenesis.. Nature medicine.,2012;18(7):1077-1086
2、Qu B, Han X, Tang Y, Shen N. #. A Novel Vector-Based Method for Exclusive Overexpression of Star-Form MicroRNAs.. PLoS One.,2012;7(7)e41504:1-10.
3、Zhou ZY, Chen SL, Shen N#, Lu Y. . Cytokines and Behcet's Disease. . Autoimmun Rev.,2012;11(10):699-704.
4、Shen N#, Liang D, Tang Y, de Vries N, Tak PP.. MicroRNAs—novel regulators of systemic lupus erythematosus pathogenesis. Nat Rev Rheumatol.,2012;8(12):701-9.
5、Liang D, Shen N. #. MicroRNA involvement in lupus: the beginning of a new tale.. Curr Opin Rheumatol.,2012;24(5):489-98.
6、Fan W, Liang D, Tang Y, Qu B, Cui H, Luo X, Huang X, Chen S, Higgs BW, Jallal B, Yao Y, Harley JB, Shen N. #. Identification of microRNA-31 as a novel regulator contributing to impaired IL-2 production in T cells from patients with systemic lupus erythematosus.. Arthritis Rheum.,2012;64(11):3715-25
7、Wang S, Tang Y, Cui H, Zhao X, Luo X, Pan W, Huang X, Shen N*#. Let-7/miR-98 regulate Fas and Fas-mediated apoptosis. Genes Immun,2011;12(2):149-54
8、Fu Q, Zhao J, Qian X, Wong JL, Kaufman KM, Yu CY; Hwee Siew Howe; Tan Tock Seng Hospital Lupus Study Group, Mok MY, Harley JB#, Guthridge JM, Song YW, Cho SK, Bae SC, Grossman JM, Hahn BH, Arnett FC, Shen N, Tsao BP*. Association of a functional IRF7 variant with systemic lupus erythematosus. Arthritis Rheum,2011;63(3):749-54
9、 Li J, Fu Q, Cui H, Qu B, Pan W, Shen N*, Bao C*. Interferon-α Priming Promotes Lipid Uptake and Macrophage-Derived Foam Cell Formation: A Novel Link between Interferon-α and Atherosclerosis in Lupus.. Arthritis Rheum,2011;63(2):492-502
10、Liao LH, Zhang H, Lai MP, Chen SL, Wu M, Shen N*#. Single-nucleotide polymorphisms and haplotype of CYP2E1 gene associated with systemic lupus erythematosus in Chinese population. Arthritis Res Ther,2011;13(1):11-11
11、Maiti AK#, Kim-Howard X, Viswanathan P, Guillén L, Qian X, Rojas-Villarraga A, Sun C, Ca?as C, Tobón GJ, Matsuda K, Shen N, Cher?avsky AC, Anaya JM, Nath SK. Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases. Rheumatology (Oxford),2010;49(7):1239-44
12、Zhou H#, Huang X, Cui H, Luo X, Tang Y, Chen S, Wu L, Shen N*. miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. Blood,2010;116(26): 5885-5894
13、Shen N*#, Fu Q, Deng Y, Qian X, Zhao J, Kaufman KM, Wu YL, Yu CY, Tang Y, Chen JY, Yang W, Wong M, Kawasaki A, Tsuchiya N, Sumida T, Kawaguchi Y, Howe HS, Mok MY, Bang SY, Liu FL, Chang DM, Takasaki Y, Hashimoto H, Harley JB, Guthridge JM, Grossman JM, Cantor RM, Song YW, Bae SC, Chen S, Hahn BH, Lau YL, Tsao BP*. Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus. Proc Natl Acad Sci(USA),2010;107(36):15838-15843
14、Zhao X#, Tang Y, Qu B, Cui H, Wang S, Wang L, Luo X, Huang X, Li J, Chen S, Shen N*. MicroRNA-125a contributes to elevated inflammatory chemokine RANTES via targeting KLF13 in systemic lupus erythematosus. Arthritis Rheum,2010;62 (11):3425-3435
15、Pan W#, Zhu S, Yuan M, Cui H, Wang L, Luo X, Li J, Zhou H, Tang Y, Shen N*. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol,2010;184(12):6773-81
16、Yang W#, Shen N, Ye DQ, Liu Q, Zhang Y, Qian XX, Hirankarn N, Ying D, Pan HF, Mok CC, Chan TM, Wong RW, Lee KW, Mok MY, Wong SN, Leung AM, Li XP, Avihingsanon Y, Wong CM, Lee TL, Ho MH, Lee PP, Chang YK, Li PH, Li RJ, Zhang L, Wong WH, Ng IO, Lau CS, Sham PC, Lau YL. Asian Lupus Genetics Consortium. Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet,2010;6(2)
17、Luo X#, Tsai LM, Shen N, Yu D. Evidence for microRNA-mediated regulation in rheumatic diseases. Ann Rheum Dis,2010;
18、Tang YJ#, Luo XB, Cui HJ, Ni XM, Yuan M, Guo YZ, Huang XF, Zhou HB, Vries N, Tak P, Chen SL, Shen N*. MicroRNA-146a Contributes to Abnormal Activation of the Type I Interferon Pathway in Human Lupus by Targeting the Key Signaling Proteins. Arthritis Rheum,2009;60(4):1065-75
19、Du F#, Lü LJ, Fu Q, Dai M, Teng JL, Fan W, Chen SL, Ye P, Shen N, Huang XF, Qian J, Bao CD. T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis. Arthritis Rheum,2008;10(6)
20、Fu Q#, Chen XQ, Cui HJ, Guo YZ, Chen J, Shen N*, Bao CD*. Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients. Arthritis Res Ther,2008;10(5)
21、Tang J#, Gu Y, Zhang M, Ye S, Chen X, Guo Q, Qian J, Bao C, Chen S, Shen N*. Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients. Lupus,2008;17(9):805-13
22、Huang XY#, Shen N*, Bao CD, Gu YY, Wu L, Chen SL. Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells. Arthritis Res Ther,2008;10(4):R91
23、Yan B#, Ye S*, Chen GJ, Kuang M, Shen N*, Chen SL. Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells. Arthritis Rheum,2008;58(3):801-12
24、Wu H#, Boackle SA, Hanvivadhanakul P, Ulgiati D, Grossman JM, Lee Y, Shen N, Abraham LJ, Mercer TR, Park E, Hebert LA, Rovin BH, Birmingham DJ, Chang DM, Chen CJ, McCurdy D, Badsha HM, Thong BY, Chng HH, Arnett FC, Wallace DJ, Yu CY, Hahn BH, Cantor RM, Tsao BP*. Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus. Proc Natl Acad Sci U S A,2007;104 (10):3961-6
25、Feng XG#, Ye S, Lu Y, Xu XJ, Gu YY, Shen N, Ye P, Cheng FP, Wang AM, Chen SL. Antikinectin autoantibody in Beh?et's disease and several other autoimmune connective tissue diseases. Clin Exp Rheumatol,2007;25(445):80-5.
26、Lu Q#, Shen N*, Li XM, Chen SL. Genomic view of IFN-alpha response in pre-autoimmune NZB/W and MRL/lpr mice. Genes Immun,2007;8(7):590-603
27、Ye S#,Guo Q,Tang JP, Yang CD, Shen N, Chen SL. Could 2'5'-oligoadenylate synthetase isoforms be biomarkers to differentiate between disease flare and infection in lupus patients? A pilot study. Clin Rheumatol,2007;26(2):186-90
28、Huang XF#,Hua J,Shen N,Chen SL. Ysregulated expression of interleukin-23 and interleukin-12 subunits in systemic lupus erythematosus patients. Modern Rheumatology,2007;17(3):220-223
29、Shen N#, Tsao BP. Current advances in the human lupus genetics. Curr Rheumatol,2004;6(5):391-8
30、Feng XB#, Shen N, Qian J, Sun L, Hua J, Chen SL. Single nucleotide polymorphisms of deoxyribonuclease I and their expression in Chinese systemic lupus erythematosus patients. Chin Med J (Engl),2004;117(11):1670-6
31、Lu LJ#, Chen SL, Gu YY, Shen N, Bao CD, Wang Y, Xue F, Ye P, Yu CZ. Transfection, overexpression and clinical application of human 60 kDa Ro/SSA autoantigens in HEp-2 cells. Chin Med J (Engl),2003;116(3):350-3
32、Ye S#, Pang H, Gu YY, Hua J, Chen XG, Bao CD, Wang Y, Zhang W, Qian J, Tsao BP, Hahn BH, Chen SL, Rao ZH, Shen N*. Protein interaction for an interferon-inducible systemic lupus associated gene,IFIT1. Rheumatology (Oxford),2003;42(10):1155-63
33、Han GM#, Chen SL, Shen N, Ye S, Bao CD, Gu YY. Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray. Genes Immun,2003;4(3):177-86
34、Tsao BP#, Cantor RM, Grossman JM, Kim SK, Strong N, Lau CS, Chen CJ, Shen N, Ginzler EM, Goldstein R, Kalunian KC, Arnett FC, Wallace DJ, Hahn BH. Linkage and interaction of loci on 1q23 and 16q12 may contribute to susceptibility to systemic lupus erythematosus. Arthritis Rheum,2002;46(11):2928-36
35、Chen SL#, Hu DW, Shi XG, Shen N, Gu YY, Bao CD. The relationship between Th1/Th2-type cells and disease activity in patients with systemic lupus erythematosus. Chin Med J (Engl),2000;113(10):877-80
36、Tsao BP#, Cantor RM, Grossman JM, Shen N, Teophilov NT, Wallace DJ, Arnett FC, Hartung K, Goldstein R, Kalunian KC, Hahn BH, Rotter JI. PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus. J Clin Invest,1999;103(8):1135-40
37、Shen N#, Chen S, Yang H, Fan L. Mixed connective tissue disease: a disease entity?. Chin Med J (Engl),1998;111(3):214-7
38、Yang CD#, Chen SL, Shen N, Qi M, Xu F. Detection of anti-recombinant beta 2-glycoprotein 1 and anti-recombinant beta 2-glycoprotein 1 fifth-domain antibodies in sera from patients with systemic lupus erythematosus. Rheumatol Int,1998;18(1):5-10
39、Yang CD#, Chen SL, Shen N. The Fifth Domain of β2-Glycorprotein 1 Contain Antigenic Epitopes Recognized by Anticardiolipin Antibodies Derived From Patients With The Antipholipid Syndrome. APLAR Journal of Rheumatology,1997;1(1):96-100
40、Tsao BP#, Cantor RM, Kalunian KC, Chen CJ, Badsha H, Singh R, Wallace DJ, Kitridou RC, Chen SL, Shen N, Song YW, Isenberg DA, Yu CL, Hahn BH, Rotter JI. Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest,1997;99(4):725-31
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