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上海交通大学医学院研究生导师简介 王祥瑞

上海交通大学 免费考研网/2013-01-10

基本信息
导师姓名: 王祥瑞 专业代码: 100217
性别: 专业名称: 麻醉学
培养单位: 仁济医院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: Xiangrui68@163.com 上海东方路1630号,仁济医院麻醉科,200127,68383198
研究方向 (点击浏览详细信息)
围术期脏器保护
慢性疼痛效应学研究
社会任职
中国医师学会麻醉分会常委
上海医学会麻醉学会副主任委员
上海医学会危重病学会委员
中华医学会疼痛分会全国委员
上海医学会疼痛专业委员会委员
中华针灸学会针刺麻醉理事会副主任委员
上海针灸学会针刺麻醉分会副主任委员
中医药促进会软组织疼痛分会副主任委员
中华医学会麻醉学分会委员会委员
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
2013CB531902针药复合麻醉在心肺手术的应用及机体保护效应国家重点基础研究发展计划9732013-01~~2017-08400万元课题负责人
81170062TLR4内源性配体HMGB1介导体外循环手术后急性肺损伤的机制国家自然科学基金2012-01~~2015-1250万元课题负责人
81071064Delta阿片受体激动剂后处理对缺血性脑损伤的保护作用及其机制研究国家自然科学基金2011-01~~2013-1233万元课题负责人
10411951600羟乙基淀粉(130/0.4)预处理用于肝移植围手术期肺保护策略的作用机制研究和临床评价上海市科委2010-07~~2013.0920万元课题负责人
沪交医科[2008]6号交大医学院麻醉学重点学科交大医学院2008-09~~2012-0950万元课题负责人
07DZ19722-4肥大细胞过度激活介导ROS-HIF通路在针麻镇痛心肌保护中的作用机制研上海市科委2008-02~~2011-0140万元课题负责人
30672019Delta阿片受体在深低温停循环脑损伤中的作用及其信号转导机制的研究国家自然基金委,面上项目2007-01~~2009-1230万元课题负责人
2007CB512504基于临床的针麻镇痛的基础研究国家973项目2007-01~~2011-12300万元课题负责人
05DZ19746针刺临床研究上海市科委,重点科技攻关2006-01~~2008-0947万元课题负责人
05HX21014全脊髓神经阻滞对神经病理性疼痛治疗作用的机制研究横向课题2005-06~~2007-065万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Zhengyu He., Yuan Gao., Yuxiao Deng, Wen Li, Yongming Chen, Shunpeng Xing, Xianyuan Zhao,Jia Ding, Xiangrui Wang*#. Lipopolysaccharide Induces Lung Fibroblast Proliferation through Toll-Like Receptor 4 Signaling and the Phosphoinositide3-Kinase-Akt Pathway.. PLoS ONE,2012;7(4):e35926
2、Song JG, Li HH, Cao YF, Lv X, Zhang P, Li YS, Zheng YJ, Li Q, Yin PH, Song SL, Wang HY, Wang XR#. Electroacupuncture improves survival in rats with lethal endotoxemia via the autonomic nervous system.. Anesthesiology.,2012;116(2):406-414
3、Xiaojie Yu,Xiangrui Wang#,John Zhang, Ying Wang. Changes in pressure pain thresholds and Basal electromyographic activity after instrument-assisted spinal manipulative therapy in asymptomatic participants: a randomized, controlled trial.. J Manipulative Physiol Ther.,2012;35(6):437-45.
4、Zheng YJ, Wang XR#, Chen HZ, Wu XJ, Zhao YH, Su DS.. Protective Effects of the Delta Opioid Peptide [D-Ala2, D-Leu5]enkephalin in an Ex Vivo Model of Ischemia/Reperfusion in Brain Slices.. CNS Neurosci Ther.,2012;18(9):762-6.
5、Zhe Liu,Zengqiang Qu,Xiaodong Li,Meihua Cai,Ping He,Mi Zhou,Jie Xiao,Xiangrui Wang#. Phenacetin O-deethylation is a useful tool for evaluation of hepatic functional reserve in rats with CCl(4)-induced chronic liver injury.. J Surg Res.,2012;175(2):e61-6.
6、Wen Li,Beijie Zheng,Huan Xu,Yuxiao Deng,Shuyan Wang,Xiangrui Wang#,Diansan Su. Isoflurane Prevents Neurocognitive Dysfunction After Cardiopulmonary Bypass in Rats.. J Cardiothorac Vasc Anesth.,2012;S1053-0770(12)00447-8.
7、Diansan Su., Yanxing Zhao., Huan Xu, Beilei Wang, Xuemei Chen, Jie Chen, Xiangrui Wang#. Isoflurane Exposure during Mid-Adulthood AttenuatesAge-Related Spatial Memory Impairment in APP/PS1Transgenic Mice. PLoS One.,2012;7(11):e50172.
8、Lv X, Song JG, Li HH, Ao JP, Zhang P, Li YS, Song SL, Wang XR#. Decreased hepatic peroxisome proliferator-activated receptor-γ contributes to increased sensitivity to endotoxin in obstructive jaundice.. World J Gastroenterol.,2011;17(48):5267-73.
9、Su D, Zhao Y, Wang B, Xu H, Li W, Chen J, Wang X.#. Isoflurane-induced spatial memory impairment in mice is prevented by the acetylcholinesterase inhibitor donepezil.. PLoS One.,2011;6(11):e27632.
10、Tian J, Wang Y, He Z, Gao Y, Rundhaug JE, Wang X.#. Hydroxyethyl Starch (130 kD) Inhibits Toll-Like Receptor 4 Signaling Pathways in Rat Lungs Challenged with Lipopolysaccharide.. Anesth Analg,2011;113(1):112-9
11、Wang S, Duan Y, Su D, Li W, Tan J, Yang D, Wang W, Zhao Z, Wang X.#. Delta opioid peptide [d-Ala2, d-Leu5] enkephalin (DADLE) triggers postconditioning against transient forebrain ischemia.. Eur J Pharmacol,2011;658(2-3):140-4.
12、Su D, Zhao Y, Wang B, Li W, Xiao J, Chen J, Wang X.#. Repeated but not single isoflurane exposure improved the spatial memory of young adult mice.. Acta Anaesthesiol Scand,2011;55(4):468-73.
13、Xiao J, Cai MH, Wang XR, He P, Wang XR.#. Time course of action and pharmacokinetics of ropivacaine in adult and elderly patients following combined lumbar plexus-sciatic nerve block. Int J Clin Pharmacol Ther,2010;48(9):608-13
14、Su D, Gu Y, Wang Z, Wang X.#. Lidocaine attenuates proinflammatory cytokine production induced by extracellular adenosine triphosphate in cultured rat microglia. Anesth Analg,2010;111(3):768-74
15、Diansan S, Shifen Z, Zhen G, Heming W, Xiangrui W.#. Resection of the nerves bundle from the sphenopalatine ganglia tend to increase the infarction volume following middle cerebral artery occlusion. Neurol Sci,2010;31(4):431-5
16、Wang XR*, Qu ZQ, Li XD, Liu HL, He P, Fang BX, Xiao J, Huang W, Wu MC.. Activity of sulfotransferase 1A1 is dramatically upregulated in patients with hepatocellular carcinoma secondary to chronic hepatitis B virus infection. Cancer Sci,2010;101(2):412-5
17、Tian J, Gu Y, Su D, Wu Y, Wang X.#. Effects of intrathecal lidocaine on hyperalgesia and allodynia following chronic constriction injury in rats. European Journal of Pain,2009;13(2):130-137
18、Ke S, Dian-san S, Xiang-rui W.#. Delta opioid agonist [D-Ala2, D-Leu5] enkephalin (DADLE) reduced oxygen–glucose deprivation caused neuronal injury through the MAPK pathway. Brain Research,2009;1292:100-106
19、Tian J, Gu Y, Su D, Wu Y, Wang X.#. In reply to ‘‘Is intrathecal lidocaine administration risk-free in rats with neuropathic pain?”. Eur J Pain.,2009;13(6):891
20、Gu YW, Su DS, Tian J, Wang XR.#. Attenuating phosphorylation of p38 MAPK in the activated microglia: a new mechanism for intrathecal lidocaine reversing tactile allodynia following chronic constriction injury in rats.. Neurosci Lett,2008;431(2):129-34.


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