上海交通大学医学院研究生导师简介范建高

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上海交通大学免费考研网/2013-01-10

基本信息

导师姓名:	范建高	专业代码:	100201
性别:	男	专业名称:	内科学
培养单位:	新华医院	三级学科/ 专业领域:	消化系病
导师类型:	博士生导师	专业学位导师:	兼
联系方式:	fanjiangao@gmail.com 新华医院消化内科, 200092, 021-25077340

研究方向 (点击浏览详细信息)

代谢综合征与肝病

脂肪性肝病

脂肪肝的遗传与表观遗传

社会任职

中华内科杂志编委

上海市医学会内科专业委员会委员

国际动脉硬化学会中国分会理事

国际肝胆胰学会中国分会内科委员

中华肝病学会脂肪肝和酒精性肝病学组组长

上海市肝病学会副主任委员

上海市中西医结合学会器官纤维化专业委员会副主委

《胃肠病学和肝病学杂志》《肝脏》《中国医学前沿》等副主编

中国医师协会脂肪肝专家委员会主任委员

J Gastroenterol Hepatol，J Dig Dis等SCI-E期刊编委

《中华肝脏病杂志》、《中华糖尿病杂志》、《中国实用内科杂志》、《中国动脉硬化杂志》等编委/常委

中国医师协会脂肪肝专家委员会主任委员

实用肝脏病杂志总编辑

中华医学会肝脏病分会委员

科研项目

项目编号	项目名称	课题来源	起止时间	科研经费	承担职责
81270491	K细胞靶向性GLPs修饰以重塑“肝肠对话”模式对非酒精性脂肪性肝炎的干预研究	国家自然科学基金	2013-01~~2016-12	70万元	课题负责人
XJS20120501	FibroScan○R实施受控衰减参数评价脂肪性肝炎肝纤维化的临床研究	中国肝炎防治基金会	2012-06~~2013-12	70万元	课题负责人
2012CB517500	脂代谢紊乱导致脂肪肝及高脂血症发生的机制：遗传学研究	国家科技部973项目课题	2012-01~~2017-01	560万元	课题负责人
2011	Nrf2-Keap1系统拮抗胰岛素抵抗依赖性氧化应激对非酒精性脂肪性肝病的防治研究	上海市卫生局新百人计划	2011-08~~2016-07	50+50万元	课题负责人
81070322	逆转TLRs/MyD88途径介导的先天免疫功能亢进对NASH的防治作用	国家自然科学基金面上项目	2011-01~~2013-12	32万元	课题负责人
201002	扶正化瘀胶囊抑制“上皮--间质转化”依赖性肌成纤维细胞生成对肝纤维化的治疗作用研究	百洋医洋集团有限公司	2010-08~~2012-07	10.0万元	课题负责人
10411956300	上海地区非酒精性脂肪性肝病预警指标体系及其干预模式的筛选和建立	上海市科委重点项目	2010-07~~2013-06	20万元	课题负责人
20090007	CTGF-ILK通路在介导肝细胞上皮-间充质转分化及肝纤维化形成中的作用研究	中国肝炎防治基金会	2010-01~~2012-12	12.0万元	课题负责人
09140903500	慢性乙型肝炎合并脂肪肝小鼠模型的建立	上海市科委，实验动物资助	2009-09~~2011-12	25万元	课题负责人

学术论文 (#为通讯作者,*为共同第一作者)

1、Duan XY, Qiao L, Fan JG.#. Clinical features of nonalcoholic fatty liver disease-associated hepatocellular carcinoma. . Hepatobiliary Pancreat Dis Int,2012;11: 11(1):18-27.
2、Wang B, Li W, Guo K, Xiao Y, Wang Y, Fan J.#. miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients.. Biophys Res Commun.,2012;421(1):4-8.
3、Wang Y, Wang B, Shen F, Fan J, Cao H.. Body Mass Index and Risk of Primary Liver Cancer: A Meta-Analysis of Prospective Studies.. Oncologist.,2012;2012 Sep 6. [Epub ahead of print]
4、Zhang Z, Pan Q, Duan XY, Liu Q, Mo GY, Rao GR, Fan JG#. Fatty liver reduces hepatitis B virus replication in a genotype B hepatitis B virus transgenic mice model.. J Gastroenterol Hepatol,2012;27(12):1858-64
5、Du YQ, Su T, Fan JG*, Lu YX, Zheng P, Li XH, Guo CY, Xu P, Gong YF, Li ZS.. Adjuvant probiotics improve the eradication effect of triple therapy for Helicobacter pylori infection.. World J Gastroenterol.,2012;18(43):6302-7.
6、Wang B, Li W, Chen Y, Wang Y, Sun C, Chen Y, Lu H, Fan J#, Li D. Coexpression of Smad7 and UPA attenuates carbon tetrachloride-induced rat liver fibrosis.. Med Sci Monit.,2012;18(10):394-401
7、Fan JG#, Jia JD, Li YM, et al.. Guidelines for the diagnosis and management of non-alcoholic fatty liver disease: update 2010.. J Dig Dis,2011;12:38-44.
8、Li YM, Fan JG#, Wang BY, et al.. Chinese Guidelines for the diagnosis and management of alcoholic liver disease: update 2010.. J Dig Dis,2011;12:45-50.
9、Cao HX,Fan JG.#. Fatty liver disease: a growing public health problem worldwide.. J Dig Dis,2011;12: 1-2.
10、Shi JP, Xun YH, Su YX, Jiang YM, Zhang L, Hu CB, Fan JG.#. Metabolic syndrome and severity of fibrosis in patients with chronic hepatitis B virus infection or nonalcoholic fatty liver disease. . J Microbiology Research,2011;5:481-485.
11、Yan SY, Hu Y, Fan JG, Tao GQ, Lu YM, Cai X, Yu BH, Du YQ. . Clinicopathologic significance of HER-2/neu protein expression and gene amplification in gastric carcinoma.. World J Gastroenterol.,2011;17:1501-6.
12、Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M, Ali MK, Riley LM, Robinson CA, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Glucose). . National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2?7 million participants. . Lancet.,2011;378(9785):31-40.
13、Farzadfar F, Finucane MM, Danaei G, Pelizzari PM, Cowan MJ, Paciorek CJ, Singh GM, Lin JK, Stevens GA, Riley LM, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Cholesterol).. National, regional, and global trends in serum total cholesterol since 1980: systematic analysis of health examination surveys and epidemiological studies with 321 country-years and 3?0 million participants.. Lancet.,2011;377(9765):578-86.
14、Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, Cowan MJ, Farzadfar F, Stevens GA, Lim SS, Riley LM, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure). . National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5?4 million participants.. Lancet.,2011;377(9765):568-77.
15、Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index). . National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9?1 million participants.. Lancet.,2011;377(9765):557-67.
16、Ge WS, Wu JX, Fan JG, Wang YJ, Chen YW.. Inhibition of high-mobility group box 1 expression by siRNA in rat hepatic stellate cells.. World J Gastroenterol.,2011;17(36):4090-8.
17、Fan JG#, Farrell GC.. Does NAFLD predispose patients to type 2 diabetes in the absence of obesity? . J Gastroenterol Hepatol,2010;25:223-225
18、Duan XY, Zhao XP, Fan JG.#. Dynamic expression of hepatic thioredoxin mRNA in rats with nonalcoholic fatty liver disease.. J Dig Dis,2010;11:94-100.
19、Xu ZJ, Fan JG#, et al.. Characterization of a high-fat diet-induced non-alcoholic steatohepatitis in rats.. Dig Dis Sci.,2010;55:931-40.
20、Asia-Pacific Working Party on Prevention of Hepatocellular carcinoma.. Prevention of Hepatocellular carcinoma in the Asia-pacific region: Consensus statements.. J Gastroenterol Hepatol.,2010;25:657-663
21、Chen YW, Liu BW, Zhang YJ, Chen YW, Dong GF, Ding XD, Xu LM, Pat B, Fan JG, Li DG. . Preservation of basal AcSDKP attenuates carbon tetrachloride-induced fibrosis in the rat liver.. J Hepatol.,2010;53:528-36.
22、Wu JY, Duan XY, Li L, Dai F, Li YY, Li XJ, Fan JG.*. Dyslipidemia in Shanghai, China.. Preventive Medicine,2010;51:412-415.
23、Fan JG.#. A tribute to Dr Guang-bi Yao (1931-2010).. J Gastroenterol Hepatol.,2010;25(6):1027-28.
24、Lin G, Duan XY, Cai XB, XY Tian, ZJ Xu, JG Fan.#. Hepatocyte steatosis increases the expression of adhesion molecules in endothelial cells.. Asian Biomedicine,2010;4:757-763.
25、 Zhou H, Li D, Cheng G, Fan J, Lu H.. An epidemiologic study of irritable bowel syndrome in adolescents and children in South China: a school-based study.. Child Care Health Dev.,2010;36:781-6.
26、Fan JG#, Farrell GC.. Epidemiology of non-alcoholic fatty liver disease in China.. J Hepatol.,2009;50:204-10.
27、Fan JG#, Farrell GC.. Prevention of hepatocellular carcinoma in non-viral related liver diseases. . J Gastroenterol Hepatol.,2009;24:712-19.
28、Fan JG*, Qiao L.. Commonly used animal models of non-alcoholic steatohepatitis.. Hepatobiliary Pancreat Dis Int,2009;8:233-240.
29、Yuen MF, Hou JL, Chutaputti A; APWP on Prevention of Hepatocellular Carcinoma. . Hepatocellular carcinoma in the Asia pacific region.. J Gastroenterol Hepatol.,2009;24:346-53.
30、Amarapurkar D, Han KH, Chan HLY, Ueno Y and APWP on Prevention of HCC. . Application of surveillance programs for HCC in the Asia–Pacific Region. . J Gastroenterol Hepatol.,2009;24:955-61.
31、Teoh N,Fan JG.. Diabetes mellitus and prognosis after curative therapy for hepatocellular carcinoma: alas, still grave for those who are hyperglycemic.. J Gastroenterol Hepatol.,2008;23:1633-4.
32、Shi J, Fan JG#, et al. . Prevalence and risk factors of hepatic steatosis and its impact on liver injury in Chinese patients with chronic hepatitis B infection.. J Gastroenterol Hepatol.,2008;23:1419-1425.
33、Fan JG#, et al. . Alcohol consumption and metabolic syndrome among Shanghai adults: A randomized multistage stratified cluster sampling investigation. . World J Gastroenterol,2008;14:2418-2424.
34、Fan JG*, Farrell GC.. VAT fat is bad for the liver, SAT fat is not!. J Gastroenterol Hepatol.,2008;23:829-32.
35、Fan JG#, Chitturi S.. Hepatitis B and fatty liver: causal or coincidental?. J Gastroenterol Hepatol.,2008;23:779-782.
36、Fan JG#, et al.. Alcohol consumption and metabolic syndrome among Shanghai adults: A randomized multistage stratified cluster sampling investigation. . World J Gastroenterol,2008;14:2418-2424.
37、Fan JG.#. Impact of nonalcoholic fatty liver disease on accelerated metabolic complications.. J Dig Dis,2008;9:63-67.
38、Zeng MD, Fan JG, et al.. Guidelines for the diagnosis and treatment of nonalcoholic fatty liver disease.. J Dig Dis,2008;9:108-112.
39、Zeng MD, Li YM, Chen CW, Lu LG, Fan JG, et al.. Guidelines for the diagnosis and treatment of alcoholic liver disease.. J Dig Dis,2008;9:113-116.
40、Ji G, Fan JG, Chen JJ, Lu LG, Xing LJ, Zheng PY, Gu HG, Wei HF, You SF, Zhu PT. Effectiveness of Danning Tablet in patients with non-alcoholic fatty liver of damp-heat syndrome type: a multicenter randomized controlled trial.. Zhong Xi Yi Jie He Xue Bao,2008;6(2):128-33
41、Fan JG#, et al. . Effects of nonalcoholic fatty liver disease on the development of metabolic disorders.. J Gastroenterol Hepatol,2007;22:1086-91.
42、Fan JG#, et al.. The importance of metabolic factors for the increasing prevalence of fatty liver in Shanghai factory workers.. J Gastroenterol Hepatol,2007;22:663-668.
43、Fan JG#, et al.. What are the risk factors and settings of nonalcoholic fatty liver disease in Asia-Pacific. . J Gastroenterol Hepatol,2007;22:794-800.
44、Farrell GC, Chitturi S, Lau GKK, Sollano JD and APWP on NAFLD. . Guidelines for the assessment and management of nonalcoholic fatty liver disease in the Asia-Pacific region: Executive summary. . J Gastroenterol Hepatol,2007;22:775-777.
45、Fan JG#, Peng YD.. Metabolic syndrome and non-alcoholic fatty liver disease: Asian definitions and Asian studies. . Hepatobiliary Pancreat Dis Int,2007;6:572-578.
46、Fan JG#, et al.. Fatty liver and the metabolic syndrome among Shanghai adults.. J Gastroenterol Hepatol,2005;20:1825-1832.
47、Fan JG#, et al.. Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. . J Hepatol,2005;43:508-514.
48、Fan JG#, et al.. Effect of lactulose on establishment of nonalcoholic steatohepatitis model. . World J Gastroenterol,2005;11:5053-5056.
49、Fan JG#, et al.. Effects of UDCA and/or low-calorie diet on steatohepatitis in rats fed a high fat diet. . World J Gastroenterol,2005;11:2346-2350.
50、Qian Y, Fan JG.#. Obesity, fatty liver and liver cancer. . Hepatobiliary Pancreat Dis Int,2005;4:173-177.
51、Fan JG; Shanghai Multicenter Clinical Cooperative Group of Danning Pian Trial.#. Evaluating the efficacy and safety of Danning Pian in the short-term treatment of patients with NAFLD: a multicenter clinical trial. . Hepatobiliary Pancreat Dis Int,2004;3:375-380
52、Fan JG#, Zhong L, Xu ZJ, Tia LY, Ding XD, Li MS, Wang GL.. Effects of low-calorie diet on steatohepatitis in rats with obesity and hyperlipidemia. . World J Gastroenterol,2003;9:2045-2049.
53、Shen L, Fan JG#, Shao Y, Zeng MD, Wang JR, Luo GH, Li JQ, Chen SY.. Prevalence of nonalcoholic fatty liver among administrative officers in Shanghai:an epidemiological survey. . World J Gastroenterol,2003;9:1106-1110.
54、Fan JG#, Chen LH, Xu ZJ, Zeng MD.. Over-expression of hepatic PAI-1 mRNA in rabbits with fatty liver. . World J Gastroenterol,2001;7:710-712.
55、#. . ,;