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上海交通大学医学院研究生导师简介 范先群

上海交通大学 免费考研网/2013-01-10

基本信息
导师姓名: 范先群 专业代码: 100212
性别: 专业名称: 眼科学
培养单位: 第九人民医院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: fanxq@sh163.net 制造局路639号眼科,200011
研究方向 (点击浏览详细信息)
眼整形眼眶病,眼表疾病,眼肿瘤
社会任职
中华医学会眼科学分会常务委员
中华医学会眼科分会眼整形眼眶病学组组长
中国眼科发展策略分委会委员
卫生部内镜专业技术考评委员会眼科专委会副主席
《中国实用眼科杂志》编委
上海市医学会眼科专业委员会侯任主任委员
第五届亚太地区眼整形外科学会主席
《中华眼科杂志》编委
《中华眼视光学与视觉科学杂志》副总编辑
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
31271029基于PSeD马来酸酯生物活性控释支架复合生长因子构建眼眶组织工程骨的研究国自然基金委,面上项目2013-01~~2016-1283万元课题负责人
12441903003眼眶外科导航内窥镜系统的研发市科委医疗器械科技支持项目2012-10~~2015-0930万元课题负责人
SHDC12012107眼眶外科内窥镜导航系统的研制和应用申康新兴前沿技术攻关2012-10~~2015-09180万元课题负责人
81170876眼眶整复手术内窥镜导航系统的关键技术研究国家自然基金2012-01~~2015-1270万元课题负责人
2012AA020507组织工程角膜临床转化863子课题2012-01~~2015-1250万元课题负责人
11410702300niche微环境诱导口腔粘膜上皮细胞进行眼表重建的转化研究市科委政府间国际合作项目2011-10~~2013-0950万元课题负责人
10JC1409100小干扰RNA协同腺病毒载体靶向杀灭肿瘤的机理研究上海市科委基础研究重点项目2010-10~~2013-0930万元课题负责人
2010B066难治性眼表疾病的分类和系统治疗的研究上海市科委白玉兰科技人才基金资助2010-06~~2011-053万元课题负责人
30973279基因修饰干细胞控释在体构建眼眶骨壁的研究国家自然基金2010-01~~2012-1233万元课题负责人
YG2009ZD102眼眶手术规划与内窥镜导航系统的研发上海交通大学医工合作项目2009-03~~2011-0240万元课题负责人
2008ZX10001-008艾滋病合并结核感染者眼部病变发病率和临床特征研究国家十一五重大重大专项子课题2009-01~~2010-1250万元主要责任人
08410702300抗体导向高内吞活性免疫毒素治疗葡萄膜恶性黑色素瘤的实验研究上海市科委国际合作项目2008-10~~2010-0925万元课题负责人
07XD14020构建血管化组织工程骨修复眼眶骨缺损的研究上海市优秀学科带头人计划2007-10~~2009-0935万元课题负责人
07JC14034缺氧调控的新型肿瘤特异性基因-siRNA共表达腺病毒载体的构建和应用上海市科委重点项目连续支持课题2007-10~~2009-1230万元课题负责人
30672273脱细胞基质为载体培养角膜内皮前体细胞构建角膜后板层及其移植的研究国家自然基金委,面上项目2007-01~~2009-1228万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、He D, Li Z, Shi W, Sun Y, Zhu H, Lin M, Shen G, Fan X#. Orbitozygomatic Fractures With Enophthalmos: Analysis of 64 Cases Treated Late. J Oral Maxillofac Surg, 2012 Mar;70(3):562-576
2、Jia R, Zhu H, Lin M, Li Z, Sun Y, Luo M, Fan X#. Clinicopathological Characteristics and Surgical Outcomes of Divided Nevus of the Eyelids: A Decade's Experience on 73 Cases. Ann Plast Surg, 2012 Feb;68(2):166-170
3、Shi W, Jia R, Li Z, He D, Fan X.#. Combination of transorbital and endoscopic transnasal approaches to repair orbital medial wall and floor fractures. J Craniofac Surg, 2012 Jan;23(1):71-74
4、Shi W, Fan X. Incidence of postoperative obstruction at different sites of lacrimal canalicular injury. Plast Reconstr Surg,2012 Apr;129(4):731-733e
5、Shi W, Fan X#. Incidence of postoperative obstruction at different sites of lacrimal canalicular injury. Plast Reconstr Surg,2012 Apr;129(4):731-733e
6、Bi X, Zhou H, Lin M, Fan X#. One-stage replacement surgery of orbital implants with noninfectious complications. J Craniofac Surg,2012 Mar;23(2):146-149e
7、Cun B, Song X, Jia R, Zhao X, Wang H, Ge S, Fan X#. Combination of oncolytic adenovirus and dacarbazine attenuates antitumor ability against uveal melanoma cells via cell cycle block. . Cancer Biol Ther,2012 Jan;15;13(2):77-84
8、Wang Z, Jia R, Ge S, He T, Zhang Y, Yang Y, Wang Y, Shi W, Ji Y, Ye F, Chen P, Lu J, Sun J, Xu X, Zhou Y, Gu P, Luo M#, Lu H, Fan X. Ocular complications of human immunodeficiency virus infection in eastern china. Am J Ophthalmol,2012 Feb;153(2):363-369
9、Ping Zhang, Renbing Jia, Lei Ying, Bo Liu, Guanxiang Qian, Xianqun Fan*#, Shengfang Ge.. WWOX-mediated apoptosis in A549 cells mainly involves the mitochondrial pathway. Mol Med Report,2012;6(1):121-4
10、Jin Li, Ming Lin, Yao Fu, Huifang Zhou, Xianqun Fan#. Secondary Reconstruction of Severe Contracted Eye Socket using Modified Ocular Conformer-Drainage Tube System. J Craniofac Surg,2012 Jul;23(4):1054-8
11、Zhu H, Yu WJ, Le Y, Wang WJ, Li F, Gui T, Wang YM, Shi WD, Ding WL, Fan XQ.#. High glucose levels increase the expression of neurotrophic factors associated with p-p42/p44 MAPK in Schwann cells in vitro. Mol Med Report,2012 Jul;6(1):179-84.
12、Huang Xiaolin,Renbing Jia, Xiaoping Zhao, Bo Liu, Haibo Wang, Jing Wang, Yixiong Zhou, Biyun Cun, Shengfang Ge and Xianqun Fan. Recombinant oncolytic adenovirus H101 combined with siBCL2: Cytotoxic effect on uveal melanoma cell lines. Br J Ophthalmol,2012 Oct;96(10):1331-8
13、Sun J., Zhou H., Deng Y., Zhang Y., Gu P., Ge S., Fan X#. Conditioned medium from Bone Marrow Mesenchymal Stem Cells transiently retards osteoblast differentiation by downregulating Runx2.. Cells Tissues Organs,2012;196(6):510-22
14、FAN XIANQUN﹡#, LU WENJUAN, ZHOU HUIFANG, XIAO CAIWEN, SHEN QIN, LIN MING, LI JIN , FU YAO, JIA RENBIN, LI ZHENGKANG. Late Correction of Orbital-zygomatic-maxillary Fractures Combined with Orbital Wall Fractures. J Craniofac Surg,2012 Nov;23(6):1672-6
15、Huang X, Wang L, Zhang H, Wang H, Zhao X, Qian G, Hu J, Ge S, Fan X.#. Therapeutic efficacy by targeting correction of notch1-induced aberrants in uveal tumors. PLoS One,2012;7(8):e44301
16、Fan J, Zhou Y, Huang X, Zhang L, Yao Y, Song X, Chen J, Hu J, Ge S, Song H, Fan X.#. The combination of polyalanine expansion mutation and a novel missense substitution in transcription factor FOXL2 leads to different ovarian phenotypes in blepharophimosis–ptosis–epicanthus inversus syndrome (BPES) patients. Hum Reprod,2012 Nov;27(11):3347-57
17、Sun J, Zhou J, Zhao P, Lian J, Zhu H, Zhou Y, Sun Y, Wang Y, Zhao L, Wei Y, Wang L, Cun B, Ge S, Fan X.#. High Prevalence of Myopia and High Myopia in 5060 Chinese University Students in Shanghai. Invest Ophthalmol Vis Sci.,2012 Nov 1;53(12):7504-9
18、Song X, Wang H, Jia R, Cun B, Zhao X, Zhou Y, Xu X, Qian G, Ge S, Fan X.#. Combined treatment with an oncolytic adenovirus and vincristine antitumor activity against retinoblastoma cells. Int. J. Mol. Sci.,2012;13(9):10736-49
19、Zhao P, Deng Y, Gu P, Wang Y, Zhou H, Hu Y, Chen P, Fan X.#. Insulin-like growth factor 1 promotes the proliferation and adipogenesis of orbital adipose-derived stromal cells in thyroid-associated ophthalmopathy. Exp eye res,2012 Dec;107C:65-73
20、Xu X,Jia R,Zhou Y,Song X,Wang J,Qian G,Ge S,Fan X. #. Reconstruction of Severe Anophthalmic Orbits and Atresic Eye Sockets After Microarray-based analysis: Identification of hypoxia-regulated microRNAs in retinoblastoma cells. International Journal of Oncology,2011 May;38(5):1385-1393
21、Wang Y,Zhou H,Xiao C,Bi X,Ji Y,Fan X#. Spontaneous Recovery of a Fronto-Orbital Blow-in Fracture in a Child. J Oral Maxillofac Surg,2011 Jun;69(6):1736-1739
22、Li J, Lin M, Zhou H, Jia R, Fan X. #. Double-eyelid blepharoplasty incorporating blepharoptosis surgery for 'latent' aponeurotic ptosis. J Plast Reconstr Aesthet Surg,2011 Aug;64(8):993-999
23、Lu L, Shi W, Luo M, Sun Y, Fan X. #. Repair of exposed hydroxyapatite orbital implants by subconjunctival tissue flaps. J Craniofac Surg,2011 Jul;22(4):1452-1456
24、Wang J, Jia R, Yao Y, Cun B, Huang X,Gu P,Ge S, Fan X. #. Differential expression of Mart-1 in human uveal melanoma cells. Mol Med Report,2011 Sep-Oct;4(5):799-803
25、Wang Y, Xiao C, Bi X, Zhou H, Ge S, Fan X. #. Palpebral Lipogranuloma Caused by Transcanalicular Ointment Injection After Laser Canaliculoplasty. Ophthal Plast Reconstr Surg,2011 Sep-Oct;27(5):333-337
26、Zhou H, Xiao C, Wang Y, Bi X, Ge S, Fan X#. In Vivo efficacy of bone marrow stromal cells coated with beta-tricalcium phosphate for the reconstruction of orbital defects in canines. Investigative Ophthalmology & Visual Science,2011 Mar;52(3):1735-1741
27、Fan J, Han B, Qiao J, Liu B, Ji Y, Ge S, Song H, Fan X. #. Functional study on a novel missense mutation of the transcription factor FOXL2 causes blepharophimosis-ptosis-epicanthus inversus syndrome (BPES). Mutagenesis,2011 Mar;26(2):283-289
28、Bi X, Fan X#, Zhou H, Shi W, Xiao C, Lin M, Li Z . Functional study on a novel missense mutation of the transcription factor Reconstruction of Severe Anophthalmic Orbits and Atresic Eye Sockets After Enucleation and Irradiation of Retinoblastoma by Vascular Anastomosed Free Dorsalis Pedis Flaps' Transplantation. J Craniofac Surg,2011 May;22(3):792-796
29、Wang W, Liu W, Zhu H,Li F,Wo Y,Shi W, Fan X#, Ding W. . Electrical stimulation promotes BDNF expression in spinal cord neurons through Ca(2+)- and Erk-dependent signaling pathways. Cell Mol Neurobiol,2011 Apr;31(3):459-67
30、Shao C, Fu Y, Lu W, Fan X. #. Bone Marrow-Derived Endothelial Progenitor Cells: A Promising Therapeutic Alternative for Corneal Endothelial Dysfunction.. Cells Tissues Organs,2011;193(4):253-263
31、Xiao C, Zhou H, Liu G, Zhang P, Fu Y, Gu P, Hou H, Tang T, Fan X#. Bone marrow stromal cells with a combined expression of BMP-2 and VEGF-165 enhanced bone regeneration. Biomedical Materials,2011 Jan;6(1):0-15013.
32、Jia R, Jiao Z, Xu X, Wang J, Zhou Y, Song X, Ge S, Fan X.#. Functional significance of B7-H1 expressed by human uveal melanoma cells. Molecular Medicine Reports,2011 Jan-Feb;4(1):163-167
33、Fan J, Wang Y, Han B, Ji Y,Song H ,Fan X#. FOXL2 mutations in Chinese families with blepharophimosis syndrome (BPES). Translational Research,2011 Jan;157(1):48-52
34、Xin Song, Yixiong Zhou, Renbin Jia, Xiaofang Xu, Haibo Wang, Jifan Hu , Shengfang Ge, Xianqun Fan#. Inhibition of retinoblastoma in vitro and in vivo with conditionally replicating oncolytic adenovirus H101. Investigative Ophthalmology and Vision Science,2010;51(5):2626-35
35、Fu Y, Fan X#, Chen P, Shao C, Lu W. Reconstruction of a tissue-engineered cornea with porcine corneal acellular matrix as the scaffold. Cells Tissues Organs,2010;191(3):193-202
36、Zhou Y, Song X, Jia R, Wang H, Dai L, Xu X, Gu P, Ge S,Fan X#. Radiation-inducible human tumor necrosis factor-related apoptosis inducing ligand (TRAIL) gene therapy:a novel treatment for radioresistant uveal melanoma. Pigment Cell & Melanoma Research,2010 Oct;23(5):661-674
37、Zhou Y, Song X, Jia R, Wang H, Dai L, Xu X, Gu P, Ge S,Fan X.#. Radiation-inducible human tumor necrosis factor-related apoptosis inducing ligand (TRAIL) gene therapy:a novel treatment for radioresistant uveal melanoma. Pigment Cell & Melanoma Research,2010 Oct;23(5):661-674
38、XQ Fan#, XP Bi, Y Fu.et al. The use of Medpor coated tear drainage tube in conjunctivodacryocystorhinostomy. Eye,2008;22:1148-1153
39、XQ Fan#, CY Shao, Y Fu, et al. Sugical Management and Outcome of Tessier Number 10 Clefts. Ophthalmology,2008;115:2290-2294


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