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上海交通大学医学院研究生导师简介 陈万涛

上海交通大学 免费考研网/2013-01-10

基本信息
导师姓名: 陈万涛 专业代码: 100301
性别: 专业名称: 口腔基础医学
培养单位: 第九人民医院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: chenwantao2002@hotmail.com 上海市制造局路639号第九人民医院8号楼413室,200011, 23271699-5211
研究方向 (点击浏览详细信息)
口腔颌面外科
社会任职
2008.10-至今 上海市重点学科(第三期)学科带头人
2008.12-至今 国家“211工程”口腔基础医学学术带头人
2010.3-至今 中华口腔医学会口腔生物医学专业委员会副主任委员
2008.3-至今 上海市医学会医学遗传学专科分会委员
美国人类遗传学会(American Society of Human Genetics)会员
Tissue engineering society international, Member
International Society for Analytic Cytology,Member
2008.5-至今 美国癌症研究学会(AACR)会员
2003.7-至今 上海市口腔医学重点实验室学术委员会 委员
2004.7-至今 《口腔颌面外科杂志》编委
2005.5-至今 《北京口腔医学》编委
2005.8-至今 《中国口腔颌面外科杂志》编委
2006.7-至今 Chinese Journal Dental Research 编委
2006.8-至今 《中国肿瘤临床》杂志审稿专家
2007.4-至今 《中华口腔医学杂志》编委
2007.11-至今 IAOMS,Member
2010.6国家自然科学基金委第十三届医学科学部专家评审组成员
2010.10上海市口腔医学会口腔基础医学专业委员会主任委员
2011.1《口腔生物医学》杂志第一届编委会副主编
2010.5Head & Neck Oncology杂志编委
2012.4 国际牙科学院院士
012.5 BMC Cancer Eiditor
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
31271341基于染色体22q13.1-13.31 区域深度测序研究Gorlin 综合征的新致病基因国家自然科学基金2013-01~~2016-1280万元主要责任人
91229103miR-143/miR-145与TLR4-NF-κB组成的信号调控网络在口腔鳞癌中的作用研究国家自然科学基金重大研究计划课题2013-01~~2015-1285万元主要责任人
11DZ2291800口腔颌面部肿瘤组织样本库建设和应用上海市科委研发平台2011-12~~2013-09100万元主要责任人
10DZ1951300口腔鳞癌早期分子诊断和个体化综合序列治疗随机、多中心研究上海市科委2010-05~~2013-09350万元子课题负责人
10XD1402500口腔颌面部鳞癌分子分型诊断方法的应用研究上海市科委学科带头人科技人才项目2010-04~~2012-0340万元课题负责人
30973343MAL基因在口腔鳞状细胞癌发生中作用的研究国家自然科学基金面上项目2010-01~~2012-1234万元课题负责人
09431902200抗癌新药新藤黄酰乙氧乙胺的临床前研究上海市科委重大新药科技攻关项目2009-07~~2012-0650万元课题负责人
S30206口腔基础医学上海市(第三期)重点学科项目2009-01~~2011-121000万元课题负责人
(07)931005基于分子药理诊断的口腔鳞癌个体化靶向治疗研究上海市领军人才“国家队”培养计划项目(“百千万人才工程”国家级人选)2008-10~~2010-0930万元课题负责人
08JC1414400基于分子药理诊断的口腔癌个体化靶向治疗研究上海市科委重点基础2008-10~~2010-0965万元课题负责人
0652nm018钛种植体表面塑性变形纳米化影响成骨细胞生物学效应与安全性研究上海市科委登山计划项目2006-09~~2008-0950万元课题负责人
30572053钛表面纳米形貌影响成骨细胞生物学行为和分子机制的研究国家自然基金委,面上项目2006-01~~2008-1228万元课题负责人
0452nm063医用材料表面纳米结构修饰对其生物兼容性影响的研究上海市科委纳米科技专项2004-01~~2006-1230万元课题负责人
30330580口腔鳞状细胞癌诊治靶点基因的筛选和功能研究国家自然科学基金重点项目2004-01~~2007-12125万元课题负责人
34107002口腔鳞癌诊断、耐药基因的筛选和应用研究上海市科委国际合作专项2003-08~~2006-1220万元课题负责人
024nm03纳米结构对细胞生长机理及应用研究上海市科委合作项目2002-09~~2004-0910万元子课题负责人
30171014口腔颌面部鳞癌细胞增殖、分化相关基因克隆和鉴定国家自然科学基金面上项目2002-01~~2004-1220万元课题负责人
39970794P-选择素及其配体影响ACC-M细胞肺转移的实验研究国家自然科学基金面上项目2000-01~~2002-1213万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Xu Q, Sun Q, Zhang J, Yu J, Chen W#, Zhang Z. Down-regulation of miR-153 Contributes to Epithelial-Mesenchymal Transition and Tumor Metastasis in Human Epithelial Cancer.. Carcinogenesis,2012 Nov 27. [Epub a;34(1):23188671-0
2、Wang X, Deng RX, Lv Y, Xu Q, Yang M, Ye DX, Chen WT#. Gambogic acid as a non-competitive inhibitor of ATP-Binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-Binding cassette transporter B1 protein degradation. Basic & Clinical Pharmacology & Toxicology,2012;2012:Doi: 10.1111/j.1742-7843
3、Wang X, Chen WT#. Gambogic Acid is a Novel Anti-cancer Agent that Inhibits Cell Proliferation. Angiogenesis and Metastasis.. Anti-Cancer Agents in Medicinal Chemistry,2012;12:994-1000
4、Feng ZE, Xu Q, Chen WT. #. Epigenetic and genetic alterations-based molecular classification of head and neck cancer.. Expert Rev. Mol. Diagn,2012;12(3), 279–290
5、Zhang JJ, Sun Q, Zhang J, Ge SF, Han ZG, Chen WT. #. Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. 。. Oncogene,2012;doi:10.1038/onc.2012.28
6、Cao W, Feng ZE, Cui ZB, Zhang CP, Sun ZY, Li M, Chen WT.#. Up-Regulation of Enhancer of Zeste Homolog 2 Is Associated Positively With Cyclin D1 Overexpression and Poor Clinical Outcome in Head and Neck Squamous Cell Carcinoma. . Cancer,2012;2858-2871
7、Feng ZE, Guo W, Zhang CP, Xu Q, Zhang P, Sun J, Zhu HG, Wang ZH, Li J, Wang LZ, Wang BS, Ren GX, Ji T, Tu WY, Yang XH, Qiu WL, Mao L, Zhang ZY, Chen WT. #. CCND1 as a predictive Biomarker of Neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma.。. PLOS ONE www.plosone.org,2011;6(10):e26399
8、Wang XD, Lv Y, Shen GF, Chen WT.#. One germline mutation of PTCH gene in a Chinese family with non-syndromic keratocystic odontogenic tumours. . International Journal of Oral and Maxillofacial Surgery,2011;40:829-833.
9、Cao W, Younis RH, Li J, Chen HY, Xia RH, Li Mao, Chen WT#, Ren HN.. EZH2 Promotes Malignant Phenotypes and Is a Predictor of Oral Cancer Development in Patients with Oral Leukoplakia.. Cancer Prev Res,2011;4(11):1816-1824
10、Song M, Xiao CC, Wang TL, Pei QG, Wang SW, Xu LQ, Chen WT#. Study of the Differentially Expressed Genes in Pleomorphic Adenoma Using cDNA Microarrays. Pathol. Oncol. Res,2011;17:765-769
11、Zhang TT, Chen MJ, Lu Y, Xing QH, Chen WT#. A novel mutation of the PTCH1 gene activates the Shh/Gli signaling pathway in a Chinese family with nevoid basal cell carcinoma syndrome. Biochemical and Biophysical Research Communications,2011;409:166-170
12、Zhang J, Cao W, Xu Q, Chen WT#. The expression of EMP1 is downregulated in oral squamous cell carcinoma and possibly associated with tumour metastasis. Clin Pathol,2011;64:25-29
13、Cao W, Zhang ZY, Xu Q, Sun Q, Yan M, Zhang J, Zhang P, Han ZG, Chen WT#. Epigenetic silencing of MAL, a putative tumor suppressor gene, can contribute to human epithelial cell carcinoma. Molecular Cancer,2010;9:296
14、Yan M, Xu Q, Zhang P, Zhou XJ, Zhang ZY, Chen WT#. Correlation of NF-kappaB signal pathway with tumor metastasis of human head and neck squamous cell carcinoma. BMC Cancer,2010;10:437
15、Xu Q, Liu XM, Cai YL, Yu YC, Chen WT#. RNAi-mediated ADAM9 gene silencing inhibits metastasis of adenoid cystic carcinoma cells. Tumor Biol,2010;DOI 10.1007/s13277-010-0034-8
16、Xu Q, Chen WT, Wang ZG, Zheng JW, Zhang ZY. . Mice transgenic with SV40-late-promoter-driven polyomavirus middle T oncogene exclusively develop hemangiomas.. Transgenic Res,2009;18(3):399-406
17、He D, Xu Q, Zhang P, Yan M, Zhou XJ, Zhang ZY,Chen WT. #. The NF-kappa B inhibitor celastrol could enhance the anti-cancer effect of Gambogic acid on oral squamous cell carcinoma.. BMC Cancer,2009;9:343doi:10.1186/1471-2407-9-343
18、Zhang P, Zhang Y, Mao L, Zhang ZY, Chen WT.#. Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes.. Cance Lett,2009;277:227-234
19、Zhou XJ, Zhang ZY, Yang X, Chen WT and Zhang P#. Inhibition of cyclin D1 expression by cyclin D1 shRNAs in human oral squamous cell carcinoma cells is associated with increased cisplatin chemosensitivity.. International Journal of Cancer,2009;124:483-489
20、Zhang MB, Zhang P, Zhang CP, Sun J, Wang LZ, Li J and Chen WT. . Prognostic significance of Bcl-2 and Bax protein expression in the patients with oral squamous cell carcinoma. . J Oral Path Med,2009;38:307-313.
21、He J, Zhou W, Zhou XJ, Zhong XX, Zhang XL, Wan PB, Zu BS, Chen WT.#. The anatase phase of nanotopognaphy titania plays an important role on osteoblast cell morphology and proliferation.. J Mater Sci: Mater Med,2008;19(11):3465-3472
22、Xu Q, Zhang ZY, Zhang P, Chen WT#. Antisense oligonucleotides and all-trans retinoic acid have a synergistic anti-tumor effect on oral squamous cell carcinoma.. BMC Cancer,2008;8:159
23、Lv Y, Zhu HG,Ye WM,Zhang MB,He D,Chen WT#. A new germline mutation of PTCH gene in a Chinese family with nevoid basal cell carcinoma syndrome. Chin Med J,2008;121(2):118-121
24、Yu YC, Chen WT*, Zhang YX, Hamburger A, Pan HY, Zhang ZY. Suppression of salivary adenoid cystic carcinoma growth and metastasis by ErbB3 Binding protein Ebp1 transfer.. Int. J. Cancer,2007;120:1909-1913
25、Jiang CH, Ye DX, Qiu WL, Zhang XL, Zhang ZY, He D, Zhang Z, Chen WT#. Response of lymphocyte subsets and cytokines to Shenyang prescription in Sprague-Dawley rats with tongue squamous cell carcinomas induced by 4NQO. BMC Cancer,2007;7:40
26、Zhang P, XU Q, Chen WT#, Zhang ZY, Li JZ, Zhou XJ. Construction of Human Tongue squamous cell Carcinoma Cell cDNA Library by in vivo Recombination in AH109. . The Chin J Dent Res,2007;10(1):30-35
27、Zhang B, Guan CC, Chen WT#, Zhang P, Yan M, Shi JH, Qin CL and Yang Q. A20 inhibits human salivary adenoid cystic carcinoma cells invasion via blocking nuclear factor-κB activation.. Chin Med J,2007;120(20):1830-1835


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