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上海交通大学医学院研究生导师简介 蒋欣泉

上海交通大学 免费考研网/2013-01-10

基本信息
导师姓名: 蒋欣泉 专业代码: 100302
性别: 专业名称: 口腔临床医学
培养单位: 第九人民医院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: xinquanj@yahoo.cn 上海市,黄浦区,制造局路639号邮编200011 Tel:21-63135412
研究方向 (点击浏览详细信息)
口腔颌面部骨组织再生种植修复的研究与应用
社会任职
2007.10至今 上海交通大学医学院附属九院,口腔修复科,副主任
2003.07至今 上海交通大学医学院附属九院,口腔生物工程/再学实验室,负责人/主任
2011.01至今 上海交通大学口腔医学院,口腔生物学教研组,主任
2011.11至今 上海市口腔医学重点实验室,副主任
国际牙科研究会(IADR)会员
国际组织工程再生医学协会(TERMIS)会员
国际口腔修复医师学会(ICP)专业会员
加拿大/中国生物材料协会(CBS)会员
亚洲骨整合学会(AAO)理事
亚洲口腔修复学会(AAP)理事会(Secretary/Editor)
中华口腔医学会口腔修复学专业委员会副主任委员
中华口腔医学会口腔生物医学专业委员会委员
中国机械工程学会表面工程分会生物材料表面工程专业委员会委员
编委:《中国口腔医学年鉴》、《上海口腔医学杂志》、《中国实用口腔科杂志》、《口腔生物医学》、《口腔材料器械》等
审稿专家:《Biomaterials》、《Cell Proliferation》、《Journal of Biomaterials Science Polymer Edition》、《Biotechnology Progress》等SCI 杂志
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
2012CB933604多级微纳结构材料促进骨组织快速修复效应国家重大科学研究计划“973”课题2012-01~~2016-12540万元主要责任人
81170939基于丝蛋白凝胶/硅介孔控释系统的可注射性组织工程骨用于犬上颌窦提升同期种植修复的研究国家自然科学基金2012-01~~2015-1268万元主要责任人
30973342Nell-1过表达促进软骨发育成熟和组织工程再生的研究国家自然科学基金2010-01~~2012-1234万元主要责任人
学术论文 (#为通讯作者,*为共同第一作者)

1、Jiang X#. On novel options for oromaxillofacial functional restoration. Int J Prosthodont,2012;25(2):132-4
2、Lü K, Zeng D, Zhang W, Xia L, Xu L, Jiang X#, Zhang F. An ectopic study of calcium phosphate cement seeded with pBMP-2 modified canine bMSCs mediated by a nonviral PEI derivative. Cell Biol Int,2012;36(2):119-28
3、Lü K, Xu L, Xia L, Zhang Y, Zhang X, Kaplan DL, Jiang X#, Zhang F. An ectopic study of apatite-coated silk fibroin scaffolds seeded with AdBMP-2 modified canine bMSCs. J BIOMAT SCI-POLYME,2012;23(1-4):509-26
4、Xu L, Lv K, Zhang W, Zhang X, Jiang X#, Zhang Q. The healing of critical-size calvarial bone defects in rat with rhPDGF-BB, BMSCs, and β-TCP scaffolds. J Mater Sci-Mater M,2012;23(4):1073-84
5、Zeng D, Xia L, Zhang W, Huang H, Wei B, Huang Q, Wei J, Liu C, Jiang X#. Maxillary sinus floor elevation using a tissue-engineered bone with bone marrow stromal cells and calcium-magnesium phosphate cement in rabbits. Tissue Eng Part A,2012;18(7-8):870-81
6、Zhao J, Shen G, Liu C, Wang S, Zhang W, Zhang X, Zhang X, Ye D, Wei J, Zhang Z, Jiang X#. Enhanced healing of rat calvarial defects with sulfated chitosan coated CDHA/BMP-2 scaffoldsMarrow Stromal Cells for Maxillary Sinus Augmentation with Simultaneous Implant Placement in Goats. Tissue Eng Part A,2012;18(1-2):185-97
7、Zou D, Guo L, Lu J, Zhang X, Wei J, Liu C, Zhang Z, Jiang X#. Engineering of Bone Using Porous Calcium Phosphate Cement and Bone Marrow Stromal Cells for Maxillary Sinus Augmentation with Simultaneous Implant Placement in Goats. Tissue Eng Part A,2012;18(13-14):1464-78
8、Zou D, He J, Zhang K, Dai J, Zhang W, Wang S, Zhou J, Huang Y, Zhang Z, Jiang X#. The bone-forming effects of HIF-1α-transduced BMSCs promote osseointegration with dental implant in canine mandible. PLoS One,2012;7(3):e32355
9、Zou D, Zhang Z, He J, Zhang K, Ye D, Han W, Zhou J, Wang Y, Li Q, Lin X, Zhang X, Wang S, Hu J, Zhu C, Zhang W, Zhou Y, Fu H, Huang Y, Jiang X#. Blood vessel formation in the tissue-engineered bone with the constitutively active form of HIF-1α mediated BMSCs. Biomaterials,2012;33(7):2097-108
10、Wu T, Xie M, Jiang X, Li J, Huang H. miR-155 modulates TNF-α-inhibited osteogenic differentiation by targeting SOCS1 expression. Bone,2012;51(3):498-505
11、Wu T, Zhou H, Hong Y, Li J, Jiang X#, Huang H. miR-30 family members negatively regulate osteoblast differentiation. J Biol Chem. J Biol Chem,2012;287(10):7503-11
12、Xia L, Xu Y, Wei J, Zeng D, Ye D, Liu C, Zhang Z, Jiang X#. Maxillary Sinus Floor Elevation Using a Tissue-engineered Bone with rhBMP-2 Loaded Porous Calcium Phosphate Cement and Bone Marrow Stromal Cells in Rabbits. Cells Tissue Organs,2011;194(6):481-9
13、Zhu C, Chang Q, Zou D, Zhang W, Wang S, Zhao J, Yu W, Zhang X, Zhang Z, Jiang X#. LvBMP-2 gene-modified BMSCs combined with calcium phosphate cement scaffolds for the repair of calvarial defects in rats. J Mater Sci Mater Med,2011;22(8):1965-73
14、Zhu C, Chang Q, Zou D, Zhang W, Wang S, Zhao J, Yu W, Zhang X, Zhang Z, Jiang X#. The study of BMP-2 gene modified canine bMSCs in promoting ectopic bone formation mediated by a nonviral PEI derivative. Ann Biomed Eng,2011;39(6):1829-39
15、Wang X, Huang H, Yang W, Xia L, Zhang W, Jiang X#, Zhang F. An ectopic study of a tissue-engineered bone complex of EMPs, pBMSCs and porous CPC scaffold in nude mice. Cell Prolif,2011;44(3):274-82
16、Xia L, Xu Y, Chang Q, Sun X, Zeng D, Zhang W, Zhang X, Zhang Z, Jiang X#. Maxillary Sinus Floor Elevation Using BMP-2 and Nell-1 Gene-Modified Bone Marrow Stromal Cells and TCP in Rabbits. Calcif Tissue Int,2011;89(1):53-64
17、Zhang D, Chu F, Yang Y, Xia L, Zeng D, Zhang X, Uluda? H, Qian Y, Jiang X#. Orthodontic tooth movement in alveolar cleft repaired with a tissue engineering bone: An experimental study in dogs. BMC Neurosci,2011;17(9-10):1313-25
18、Yu W, Zhao W, Zhu C, Zhang X, Ye D, Zhang W, Zhou Y, Jiang X#, Zhang Z. Sciatic nerve regeneration in rats by a promising electrospun collagen/poly(ε-caprolactone) nerve conduit with tailored degradation rate. BMC Neurosci,2011;15(12):68
19、Zou D, Zhang Z, Ye D, Tang A, Deng L, Han W, Zhao J, Wang S, Zhang W, Zhu C, Zhou J, He J, Wang Y, Xu F, Huang Y, Jiang X#. Repair of Critical-Sized Rat Calvarial Defects Using Genetically Engineered BMSCs Overexpressing HIF-1α. Stem Cells,2011;29:1380-1390
20、Wang S, Zhang W, Zhao J, Ye D, Zhu C, Yang Y, Zhang X, Sun X, Yang C, Jiang X#, Zhang Z. Long-term outcome of cryopreserved bone-derived osteoblasts for bone regeneration in vivo. Biomaterials,2011;32(20):4546-55
21、Wang S, Zhao J, Zhang W, Ye D, Yu W, Zhu C, Zhang X, Sun X, Yang C, Jiang X#, Zhang Z. Maintenance of phenotype and function of cryopreserved bone-derived cells. Biomaterials,2011;32(15):3739-49
22、Zou D, Zhang Z, He J, Zhu S, Wang S, Zhang W, Zhou J, Xu Y, Huang Y, Wang Y, Han W, Zhou Y, Wang S, You S, Jiang X#, Huang Y. Repairing critical-sized calvarial defects with BMSCs modified by a constitutively active form of hypoxia-inducible factor-1a and a phosphate cement scaffold. Biomaterials,2011;32(36):9707-18
23、Zhang W, Wang X, Wang S, Zhao J, Xu L, Zhu C, Zeng D, Chen J, Zhang Z, Kaplan DL, Jiang XY, Han W, Zhou Y, Wang S, You S, Jiang X#, Huang Y. The use of injectable sonication-induced silk hydrogel for VEGF165 and BMP-2 delivery for elevation of the maxillary sinus floor. Biomaterials,2011;32(35):9415-24
24、Xia L, Zhang Z, Chen L, Zhang W, Zeng D, Zhang X, Chang J, Jiang X. Proliferation and osteogenic differentiation of human periodontal ligament cells on akermanite and β-TCP bioceramics. Eur Cell Mater,2011;22: 68-83
25、Zhang Y, Yu W, Jiang X, Lv K, Sun S, Zhang F. Analysis of the cytotoxicity of differentially sized titanium dioxide nanoparticles in murine MC3T3-E1 preosteoblasts. J Mater Sci-Mater M,2011;22(8):1933-45
26、Zou D, Han W, You S, Ye D, Wang L, Wang S, Zhao J, Zhang W, Jiang X, Zhang X, Huang Y. In vitro study of enhanced osteogenesis induced by HIF-1α-transduced bone marrow stem cells. Cell Prolif,2011;44(3):234-43
27、Yu W, Jiang X, Xu L, Zhao Y, Zhang F, Cao X. Osteogenic gene expression of canine bone marrow stromal cell and bacterial adhesion on titanium with different nanotubes. J Biomed Mater Res B,2011;99(2):207-16
28、Sun XJ, Xia LG, Chou LL, Zhong W, Zhang XL, Wang SY, Zhao J, Jiang XQ#, Zhang ZY. Maxillary sinus floor elevation using a tissue-engineered bone complex with BMP-2 gene modified bMSCs and an novel porous ceramic scaffold in rabbits. Arch Oral Biol,2010;55(3):195-202
29、Zhao J, Hu J, Wang SY, Sun X, Xia L, Zhang X, Zhang Z,Jiang X#. Combination of β-TCP and BMP-2 gene-modified bMSCs to heal critical size mandibular defects in rats. Oral Dis,2010;16(1):46–54
30、Zou DR, Guo L, Lu JY, Zhang XL,Zhang ZY,Jiang XQ#. Anatomic and histological analysis in a goat model used for maxillary sinus floor augmentation with simultaneous implant placement. Clin Oral Implants Res,2010;21(1):65–70
31、Wang S, Zhang Z, Xia L, Zhao J, Sun X, Zhang X, Ye D, Uluda? H, Jiang X#. Systematic evaluation of a tissue-engineered bone for maxillary sinus augmentation in large animal canine model. Bone,2010;46(1):91-100
32、Xie M, Jiao T, Chen Y, Xu C, Li J, Jiang X, Zhang F. EMMPRIN (basigin/CD147) is involved in the morphogenesis of tooth germ in mouse molars. Histochem Cell Biol,2010;133(5):585-94
33、Wang L, Huang Y, Pan K, Jiang X, Liu C. Osteogenic Responses to Different Concentrations/Ratios of BMP-2 and bFGF in Bone Formation. Ann Biomed Eng,2010;38(1):77-87
34、Huang Y, Ren J, Ren T, Gu S, Tan Q, Zhang L, Lv K, Pan K, Jiang X. Bone marrow stromal cells cultured on poly (lactide-co-glycolide)/nano-hydroxyapatite composites with chemical immobilization of Arg-Gly-Asp peptide and preliminary bone regeneration of mandibular defect thereof. J Biomed Mater Res A,2010;95A(4):993-1003
35、Wu Z, Zhang Z, Jiang X, Guo L. Comparison of dental education and professional development between mainland China and North America. Eur J Dent Educ,2010;14(2):106-12
36、Yu W, Zhang Y, Jiang X, Zhang F. In vitro behavior of MC3T3-E1 preosteoblast with different annealing temperature titania nanotubes. Oral Dis,2010;16(7):624-30
37、Yu W, Jiang X, Zhang F, Xu L. The effect of anatase TiO(2) nanotube layers on MC3T3-E1 preosteoblast adhesion, proliferation, and differentiation. J Biomed Mater Res A,2010;94(4):1012-22
38、Jiang X, Zhao J, Wang S, Sun X, Zhang X, Chen J, Kaplan DL, Zhang Z. Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs. Biomaterials,2009; 30(27):4522-32
39、Wang S, Zhang Z, Zhao J, Zhang X, Sun X, Xia L, Chang Q, Ye D, Jiang X#. Vertical alveolar ridge augmentation with β-tricalcium phosphate and autologous osteoblast in canine mandible. Biomaterials,2009; 30(13):2489- 98
40、Hu JZ, Zhang ZY, Zhao J, Zhang XL, Liu GT, Jiang XQ#. An ectopic study of tissue-engineered bone with Nell-1 gene modified rat bone marrow stromal cells in nude mice. Chin Med J,2009;122(8):972-9
41、Zhao J, Zhang Z, Wang S, Sun X, Zhang X, Chen J, Kaplan DL,Jiang X#. Apatite-coated silk fibroin scaffolds to healing mandibular border defects in canines. Bone,2009;45(3):517-27
42、Guan CC, Yan M, Jiang XQ, Zhang P, Zhang XL, Li J, Ye DX, Zhang FQ. Sonic hedgehog alleviates the inhibitory effects of high glucose on the osteoblastic differentiation of bone marrow stromal cells. Bone,2009;45(6):1146-52
43、Jiang XQ, Sun XJ, Lai HC, Zhao J, Wang SY, Zhang ZY. Maxillary sinus floor elevation using a tissue-engineered bone complex with β-TCP and BMP-2 gene-modified bMSCs in rabbits. Clin Oral Implant Res,2009;20(12):1333-40
44、Liu X, Huang W, Fu H, Yao A, Wang D, Pan H, Lu W, Jiang X, Zhang XL. Bioactive borosilicate glass scaffolds: in vitro degradation and bioactivity behaviors. J Mater Sci Mater M,2009; 20(6):1237-43
45、Zhang X, Fu H, Liu X, Yao A, Wang D, Huang W, Zhao Y, Jiang X#. In vitro bioactivity and cytocompatibility of porous scaffolds of bioactive borosilicate glasses. Chinese Sci Bull,2009;54(18):3181-86
46、Wang Y, Zheng J, Fei Z, Jiang X, Wang Z, Fei J, Zhang Z. A novel transgenic mice model for venous malformation. Transgenic Res,2009;18(2):193-201
47、Zhang S, Tian F,Jiang X, Li J, Xu C, Guo X, Zhang F. Evidence for Calcifying Nanoparticles in Gingival Crevicular Fluid and Dental Calculus in Periodontitis. J Periodontol,2009;80(9):1462-70
48、Sun XJ, Zhang ZY, Wang SY, Gittens SA, Jiang XQ#, Chou LL. Maxillary sinus floor elevation using a tissue-engineered bone complex with OsteoBoneTM and bMSCs in rabbits. Clin Oral Implant Res,2008;19(8):804-13
49、Zhong W, Xu C, Zhang F, Jiang X, Zhang X, Ye D. Cyclic stretching force-induced early apoptosis in human periodontal ligament cells. Oral Dis,2008;14(3):270-6
50、Ning J, Yao A, Wang D, Huang W, Fu H, Liu X, Jiang X, Zhang X. Synthesis and in vitro bioactivity of a borate-based bioglass. Mater Lett,2007;61(30):5223-6
51、Cowan C, Jiang X, Hsu T, Soo C, Zhang B, Wang J, Kuroda S, Wu B, Zhang ZY, Zhang XL, Ting K. Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts. J Bone Miner Res,2007;22(6):918-30
52、Aghaloo T, Jiang X, Soo C, Zhang Z, Zhang X, Hu J, Pan H, Hsu T, Wu B, Ting K, Zhang X. A study of the role of Nell-1 gene modified goat bone marrow stromal cells in promoting new bone formation. Mol Ther,2007;15(10):1872-80
53、Jiang X, Bai J, Gittens SA, Uluda? H. Growth of bone marrow stromal cells on RGD-grafted thermoreversible (NiPAM) polymers. Materialwissenschaft und Werkstofftechnik,2006;37(6):462-468
54、Jiang X, Gittens SA, Chang Q, Zhang X, Chen C, Zhang Z. The use of tissue-engineered bone with human bone morphogenetic protein-4-modified bone-marrow stromal cells in repairing mandibular defects in rabbits. Int J Oral Maxillofac Surg,2006;35(12):1133-9
55、Zhang X, Cowan C, Jiang X, Soo C, Miao S, Carpenter D, Wu B, Kuroda S, Ting K. Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development. Lab Invest,2006;86(7):633-44
56、Jiang X, Chen J, Gittens S, Chen C, Zhang X, Zhang Z. The ectopic study of tissue-engineered bone with hBMP-4 gene modified bone marrow stromal cells in rabbits. Chin Med J,2005;118 (4):281-8


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