上海交通大学医学院研究生导师简介陈海冰

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上海交通大学免费考研网/2013-01-10

基本信息

导师姓名:	陈海冰	专业代码:	100201
性别:	女	专业名称:	内科学
培养单位:	第六人民医院	三级学科/ 专业领域:	内分泌与代谢病
导师类型:	硕士生导师	专业学位导师:	兼
联系方式:	hbchen72@yahoo.com.cn 上海市宜山路600号，上海市第六人民医院，内分泌科，200233，86-21-64369181-8570

研究方向 (点击浏览详细信息)

糖尿病发病机制及相关慢性并发症

性腺疾病

社会任职

中华医学会上海市内分泌学会青年委员

科研项目

项目编号	项目名称	课题来源	起止时间	科研经费	承担职责
2012CB517700	代谢性炎症对慢性肾脏病进展和肾纤维化的促进作用及其机制	973计划研究专项课题	2011-08~~2016-07	24.8万元	课题参与人
81070649	PGC-1α调控的线粒体ROS通路在2型糖尿病肾病早期发病中的作用	国家自然科学基金面上项目	2011-01~~2013-12	32万元	课题负责人
	Role of PGC-1α-mediated mitochondrial ROS pathway in nephropathy in type 2 diabetes	欧洲糖尿病研究基金会项目	2011-01~~2013-12	90万元	课题负责人
30871204	色素上皮源因子在氧化应激导致的胰岛β细胞损伤中作用机制及意义	国家自然基金委,面上项目	2009-01~~2011-12	33万元	课题负责人
BXJ0633	糖尿病肾病血清和尿液蛋白组和代谢组研究	上海交通大学博士创新基金	2006-01~~2007-12	2万元	课题负责人

学术论文 (#为通讯作者,*为共同第一作者)

1、Chen H*, Zheng Z, Huang Y, Guo K, Lu J, Zhang L, Yu H, Bao Y, Jia W. . microalbuminuria threshold to predict the risk for the development of diabetic retinopathy in type 2 diabetes mellitus patients.. Plos one,2012;7(5):e36718
2、Chen H*, Lu J, Chen X, Yu H, Zhang L, Bao Y, Lu F, Tang J, Gu C, Jia W.. Low serum levels of the innate immune component ficolin-3 is associated with insulin resistance and predicts the development of type 2 diabetes.. J Mol Cell Biol.,2012;4(4):256-7.
3、Zheng Z, Chen HB*, Zhao H, Liu K, Luo DW, Chen YD, Chen YH, Yang XL, Gu Q, Xu X. . Inhibition of JAK2/STAT3-mediated VEGF upregulation under high glucose conditions by PEDF through a mitochondrial ROS pathway in vitro.. Invest Ophthalmol Vis Sci,2010;51(1):64-71.
4、Chen HB, Zheng Z, Li RX, Lu JX, Bao YQ, Ying XF, Zeng R, Jia WP.. Urinary pigment epithelium-derived factor as a marker of diabetic nephropathy. . Am J Nephrol, 2010;32(1):47-56.
5、Zheng Z, Chen HB*, Wang H, Ke BL, Zheng BQ, Li Q, Li PY, Su L, Gu Q, Xu X. . Improvement of retinal vascular injury in diabetic rats by statins is associated with the inhibition of mitochondrial ROS pathway mediated by PGC-1α. Diabetes,2010; 2010 Jun 21. [Epub ahead of print]
6、Chen HB, Lu JX, Li Q, Bao YQ, Tang JL, Lu HJ, Xiang KS, Jia WP. . The protective effect of the RAS inhibitor on diabetic patients with nephropathy in the context of VEGF suppression.. Acta Pharmacol Sin.,2009;30(2):242-250.
7、Zheng Z, Chen HB*, Ke GJ, Fan Y, Zou HD, Sun XD, Gu Q, Xu X, Ho PC. . The protective effect of perindopril on diabetic retinopathy is associated with decreased VEGF/PEDF ratio: involvement of a mitochondria-ROS pathway.. Diabetes,2009;58(4):954-964.
8、Li RX, Chen HB*, Tu K, Zhao SL, Zhou H, Li SJ, Dai J, Li QR, Nie S, Li YX, Jia WP, Zeng R, Wu JR.. The significance of tumor necrosis factor-alpha in newly diagnosed type 2 Localized-statistical quantification of human serum proteome associated with type 2 diabetes.. PLoS One.,2008;16;3(9):e3224
9、Chen H, Jia W, Xu X, Fan Y, Zhan D, Wu H, Xie Z, Zheng Z.. Upregulation of PEDF expression by PARP inhibition contributes to the decrease in hyperglycemia-induced apoptosis in HUVECs. . Biochem Biophys Res Commun.,2008;369:718-724.
10、Chen H, Ren A, Hu S, Mo W, Xin X, Jia W.. The significance of tumor necrosis factor-alpha in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment.. Diabetes Res Clin Pract,2007;75:327-332.
11、Zheng Z, Chen HB, Xu X, Li C, Gu Q. . Effects of angiotensin-converting enzyme inhibitors and β-adrenergic blockers on retinal vascular endothelial growth factor expression in rat diabetic retinopathy. . Exp Eye Res,2007;84:745-752.