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上海交通大学医学院研究生导师简介 殷善开

上海交通大学 免费考研网/2013-01-10

基本信息
导师姓名: 殷善开 专业代码: 100213
性别: 专业名称: 耳鼻咽喉科学
培养单位: 第六人民医院 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: yinshankai@china.com
研究方向 (点击浏览详细信息)
耳聋的机制与防治
鼾症的诊治
社会任职
中华医学会上海分会耳鼻咽喉科学会 顾问(卸任副主委)
中华医学会耳鼻咽喉科学会 委员
中国医师协会耳鼻咽喉科医师分会 常务副主任
中国民政康复医学会听力言语专业委员会 常务委员
中华耳科学杂志 副主编
中华耳鼻咽喉头颈外科杂志 编委
上海交通大学耳鼻咽喉科研究所 所长
上海交通大学耳鼻咽喉科研究所 所长
上海交通大学眩晕疾病诊治中心 主任
上海东方耳鼻咽喉科研究所 所长
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
201202001国产人工耳蜗及临床技术研究卫生部行业基金2012-01~~2014-12176万元课题负责人
81170920miR-96参与老年性聋小鼠DBA/2J毛细胞凋亡的机制国家自然科学基金面上项目2012-01~~2015-1265万元课题负责人
2011CB504503耳蜗毛细胞损伤及保护机制的研究国家重点基础研究发展计划2011-01~~2014-12250万元课题负责人
XIAP耳蜗局部转染防治耳聋上海市领军人才2011-01~~2013-12100万元课题负责人
SHDC12010209基于阻塞平面定位的OSAHS外科治疗上海市市级医院新兴前沿技术联合攻关项目2010-04~~2013-03150万元课题负责人
30925035XIAP耳蜗局部转染防治耳聋国家杰出青年科学基金2010-01~~2013-12200万元课题负责人
2009CB526504XIAP耳蜗局部转染治疗老年性聋的实验研究973计划前期研究专项2009-04~~2011-0970万元课题负责人
08XD1403100XIAP耳蜗局部转染对耳聋的防治作用上海市科委优秀学科带头人计划2008-08~~2010-0950万元课题负责人
30672294XIAP过度表达对顺铂和噪音所致耳蜗损伤的保护作用国家自然基金委,面上项目2007-01~~2009-1228万元课题负责人
学术论文 (#为通讯作者,*为共同第一作者)

1、Wang H, Murphy R, Taaffe D, Yin S#, Xia L, Hauswirth WW, Bance M, Robertson GS, Wang J. Efficient cochlear gene transfection in guinea-pigs with adeno-associated viral vectors by partial digestion of round window membrane. Gene Ther,2012;19(3):255-63.
2、Wang H, Yin S#, Yu Z, Huang Y, Wang J. Dynamic changes in hair cell stereocilia and cochlear transduction after noise exposure. Biochem Biophys Res Commun,2011;17;409(4):616-21
3、CY Li, HB Shi, HB Ye, NY Song, SK Yin#. Bilirubin facilitates depolarizing GABA/glycinergic synaptic transmission in the ventral cochlear nucleus of rats. Eur J Pharmacol,2011;25;660(2-3):310-7.
4、CY Li, HB Shi, HB Ye, NY Song, SK Yin#. Bilirubin enhances neuronal excitability by increasing glutamatergic transmission in the rat. Toxicology,2011;18;284(1-3):19-25.
5、Li CY, Shi HB, Chen ZN, Ye HB, Song NY, Yin SK#. Protein kinase A and C signaling induces bilirubin potentiation of GABA/glycinergic synaptic transmission in rat ventral cochlear nucleus neurons.. Brain Res,2010;12;1348:30-41
6、Feng Y, Yin S#, Wang J. Deterioration of cortical responses to amplitude modulations of low-frequency carriers after high-frequency cochlear lesion in guinea pigs. Int J Audiol,2010;49(3):228-37.
7、Feng Y, Yin S#, Wang J. Deterioration of cortical responses to amplitude modulations of low-frequency carriers after high-frequency cochlear lesion in guinea pigs. Int J Audiol,2010;49(3):228-37.
8、Chen Z, Dongzhen, Wu Y, Shi H, Zhou H, Wang J, Miyoshi A, Yin S.#. Surgical treatment of labyrinthine fistula caused by cholesteatoma with semicircular canal occlusion. Acta Otolaryngol,2010;130(1):75-8
9、Ruan Q, Chen D, Wang Z, Chi F, He J, Wang J, Yin S#. Off-channel effect of high-frequency Effects of Kir2.1 gene transfection in cochlear hair cells and application of neurotrophic factors on survival and neurite growth of co-cultured cochlear spiral ganglion neurons. Mol Cell Neurosci,2010;43(3):326-39.
10、Feng Y, Yin S#, Kiefte M,Wang J.. Temporal resolution in regions of normal hearing and speech perception in noise for adults with sloping high-frequency hearing loss. Ear Hear,2010;31(1):115-25
11、Wang J, Menchenton T, Yin S#, Yu Z, Bance M, Morris DP, Moore CS, Korneluk RG, Robertson GS.. Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice.. Neurobiol Aging,2010;31(7):1238-49
12、Wang J, Menchenton T, Yin S#, Yu Z, Bance M, Morris DP, Moore CS, Korneluk RG, Robertson GS.. Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice.. Neurobiol Aging,2010;31(7):1238-49
13、Chen Z, Yu D, Feng Y, Su K, Wang J, Yin S. Off-channel effect of high-frequency overstimulation on duration tuning of low-frequency inferior colliculus neurons in guinea pigs.. Acta Otolaryngol,2009;129(12):1451-5
14、Chen Z, Yu D, Wu Y, Zhou H, Shi H, Yin S#. Indications and common surgical approaches for cochlear implantation in China. ORL J Otorhinolaryngol Relat Spec,2009;71(4):187-91
15、Yi HL, Lu WY, Guan J, Wu HM, Cao ZY, Yin SK#. Z-palatopharyngoplasty for obstructive sleep apnea/hypopnea syndrome.. ORL J Otorhinolaryngol Relat Spec,2009;247(1):40-
16、Feng Y, Jian W, Yin S.#. Cortical responses to amplitude modulation in guinea pigs and the effects of general anesthesia by pentobarbital. Hear Res,2009;140(5):640-5
17、Chen B, Yu D, Chen Z#, Yin S. Fos expression in the rat vestibular nucleus complex after plugging the three semicircular canals. Audiol Neurootol,2009;8;14(4):209-213
18、Yu D, Yin S#, Chen Z. Effect of baclofen on neuronal activity in the medial vestibular nucleus after unilateral surgical labyrinthectomy in rats. Acta Otolaryngol.,2009;129(7):735-40
19、Yu D, Yin S#, Chen Z. Effect of baclofen on neuronal activity in the medial vestibular nucleus after unilateral surgical labyrinthectomy in rats. Acta Otolaryngol.,2009;129(7):735-40
20、Ruan Q, Chen D, Wang Z, Chi F, Yin S#, Wang J. Topological and Developmental Expression Gradients of Kir2.1, an Inward Rectifier K Channel, in Spiral Ganglion and Cochlear Hair Cells of Mouse Inner Ear. Dev Neurosci,2008;30(6):374-88
21、Yin S#, Chen Z, Feng Y, Wang J. Local Inhibition Shapes Duration Tuning in The Inferior Colliculus of Guinea Pigs. Hear Res,2008;237(1-2):32-48
22、Yin S#, Feng Y, Chen Z,Wang J. The effect of noise-induced sloping high-frequency hearing loss on the gap response in the inferior colliculus and auditory cortex of guinea pigs. Hear Res,2008;239(1-2):126-40.


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