删除或更新信息,请邮件至freekaoyan#163.com(#换成@)

上海交通大学医学院研究生导师简介 时玉舫

上海交通大学 免费考研网/2013-01-10

基本信息
导师姓名: 时玉舫 专业代码: 071009
性别: 专业名称: 细胞生物学
培养单位: 健康科学研究所 三级学科/
专业领域:
未设
导师类型: 博士生导师 专业学位导师:
联系方式: shiyufang2@gmail.com 上海市重庆南路225号健康科学研究所(200025)
研究方向 (点击浏览详细信息)
间充质干细胞的免疫调节
肿瘤免疫学
不同T细胞群体的AICD过程
社会任职
American Journal of Translational Research编委
Journal of Biomedicine and Biotechnology编委
Journal of Biological Chemistry编委
Journal of Molecular Cell Biology编委
Cell & Biosciences副主编
Cellular & Molecular Immunology编委
国际细胞治疗学会间充质干细胞分会委员
Stem Cells Translational Medicine编委
Cell Death & Disease主编
Stem Cell Research & Therapy编委
中国免疫学会第六届理事会理事
中国生物医学工程学会干细胞工程技术分会委员
Oncogene Section Editor
科研项目
项目编号项目名称课题来源起止时间科研经费承担职责
31010103908间充质干细胞与免疫系统的相互作用:基础及应用研究国家基金委国际合作项目2011-01~~2013-12200万元主要责任人
2011DFA30630肿瘤基质干细胞的免疫调节作用及其临床意义研究科技部中加合作项目2011-01~~2013-12260万元主要责任人
2010CB945600组织干细胞的干性维持、分化控制和免疫调节研究科技部973重大科学研究计划2010-01~~2015-122200万元主要责任人
PJ[2009]01267肿瘤基质细胞对肿瘤发生和发展的影响上海市科委浦江人才计划项目2009-09~~2011-0850万元主要责任人
SIBS2008005淋巴细胞凋亡及存活机制的研究中国科学院上海生命科学研究院“首席科学家”项目2008-10~~2011-10300万元主要责任人
学术论文 (#为通讯作者,*为共同第一作者)

1、Shi Y*, Wei L, Wang Y, Ren G . Stem Cells Deployed for Bone Repair Hijacked by T Cells. Cell Stem Cell,2012;10:6-8
2、Shi Y*, Su J, Roberts AI, Shou P, Rabson AB, Ren G. How mesenchymal stem cells interact with tissue immune responses . Trends Immunol,2012;33(3):136-143
3、L’huillier A, Ren G, Shi Y#, Zhang J. A two-hit model of autoimmunity: lymphopenia and unresponsiveness to TGF-β signaling. Cell Mol Immunol,2012;9(5):369-70
4、Li W, Ren G, Huang Y, Su J, Han Y, Li J, Chen X, Cao K, Chen Q, Shou P, Zhang L, Yuan ZR, Roberts AI, Shi S, Le AD, Shi Y #. Mesenchymal stem cells: a double-edged sword in regulating immune responses. Cell Death & Differenciation,2012;19(9):1505-1513
5、Swaims AY, Khani F, Zhang Y, Roberts AI, Devadas S, Shi Y#, Rabson AB . Immune activation induces immortalization of HTLV-1 LTR-Tax transgenic CD4+ T-cells . Blood,2010;116(16):2994-3003.
6、Ren GW, Zhao X, Zhang LY, Zhang JM, L’Huillier A, Ling WF, Roberts AI, Le AD, Shi ST, Shao CS, Shi YF#. Inflammatory Cytokine-Induced Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Mesenchymal Stem Cells Are Critical for Immunosuppression. Journal of Immunology,2010;184(5):2321-2328
7、Shi YF*, Hu GZ, Su JJ, Li WZ, Chen Q, Shou PS, Xu CL, Chen XD, Huang Y, Zhu ZX, Huang X, Han XY, Xie NX, Ren GW . Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair . Cell Research,2010;20(5):519-528
8、Zhao X, Ren GW, Liang L, Zheng B, Tischfield JA, Shi YF, Shao CS#. Brief report: IFN-g induces expansion of Lin-Sca-1+C-Kit+ Cells. Stem Cells,2010;28(1):122-126.
9、Qian Y, Shi Y#. Natural killer cells go inside: entosis versus cannibalism. Cell Research,2009;9:1320-1321
10、Das J, Ren GW, Zhang LY, Roberts IA, Zhao X, Bothwel ALM, Kaer LV, Shi YF#, Das G. Transforming growth factor β is dispensable for the molecular orchestration of Th17 cell differentiation. The Journal of Experiment Medicine,2009;28 Sep, Epub
11、Ren G, Su J, Zhang L, Zhao X, Ling W, L'huillie A, Zhang J, Lu Y, Roberts AI, Ji W, Rabson AB, Shi YF#. Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression. Stem Cells,2009;27:1954-1962
12、Xu G, Zhang Y, Zhang L, Roberts AI, Shi YF#. C/EBP? Mediates the Synergistic Upregulation of Gene Expression by IFN-? and TNF-? in Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells,2009;27:942-984
13、Yuan ZR and Shi YF. Chloramphenicol induces abnormal cell differentiation and inhibits apoptosis in activated T cells: possible links to leukemogenesis. Cancer Research,2008;68:4875-4881
14、Zhang YY, Xu GW, Zhang LY, Roberts AI, Shi YF#. Th17 Cells Undergo Fas-mediated Activation-induced Cell Independent of IFN-?. Journal of Immunology,2008;181:190-196
15、Ren GW, Su JJ, Zhao X, Zhang LY, Zhang JM, Roberts AI, Zhang HT, Das G, Shi YF#. Apoptotic cells induce immunosuppression through dendritic cells: critical roles of IFN-gamma and nitric oxide. Journal of Immunology,2008;181:3277-3284
16、Ren GW, Zhang LY, Zhao X, Xu GW, Zhang YY, Roberts AI, Zhao RC, Shi YF#. Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide. Cell Stem Cell,2008;2:141-150
17、Wang K, Desai B, Shi YF#, Denhardt DT. Mesenchymal Stem Cell-Mediated Osteopontin Regulates Hindlimb-unloading-induced Lymphoid Organ Atrophy through Modulating Corticosteroid Production. PNAS,2007;104:14777-14782
18、Ehirchiou D, Amarnath S, Xiong Y, Xu GU, Chen WJ, Shi YF#, Zhang L. CD11b Facilitates the Development of Peripheral Tolerance by Suppressing Th17 Differentiation. The Journal of Experiment Medicine,2007;204:1519-1524
19、Xu GW, Zhang LY, Ren GW, Yuan ZR, Zhang YY, Zhao RC, Shi YF#. Immunosuppressive properties of cloned bone marrow mesenchymal stem cells. Cell Research,2007;17:240-248
20、Xu GW and Shi YF. Apoptosis signaling pathways and lymphocyte homeostasis. Cell Research,2007;17:759-771
21、Devadas S Das, Liu J, Zhang C, Roberts L, Pan AI, Moore Z., P Das G, Shi YF#. Apoptosis Modulates the Th1/Th2 Balance: Distinct Roles for Caspases and Granzyme B. Immunity,2006;25:237-247
22、Das J, Eynott P, Van Kaer L, Das G, Shi YF#. NKT cells and CD8+ T-cells are dispensable for T-cell dependent allergic airway inflammation. Nature Medicine,2006;12:1345-1346
23、Das G, Mittal J, Zhang YY, Bothwell A, Van Kare Luc, Shi YF#. Pivotal Roles of Major Histocompatibility Complex Class Ib Restricted CD8+ T Cells in Autoimmune Diseases. The Journal of Experiment Medicine,2006;203:2603-2611
24、Shi YF#, Devadas A. Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) and T-Cell Responses: What We Do and Don't Know . Cell Research,2006;16:126-133
25、Devadas S, Das J, Liu C, Zhang LY, Roberts AI, Pan Z, Moore PA, Das G, Shi YF#. Granzyme B Is Critical for T Cell Receptor-Induced Cell Death of Type 2 Helper T Cells. Immunity,2006;25:237-247
26、Yuan ZR, Wang RX, Lou XY, Zhang LY, Shi YF#. Identification and Characterization of a Novel Cell Survival Gene Critical in Apoptosis and Tumorigenesis . Cancer Research,2005;65:10716-10724


版权所有 ? 2009 上海交通大学研究生院医学院分院上海市重庆南路227号 邮编:200025
电子邮件:yjsy@shsmu.edu.cn 总机:63846590
相关话题/导师 医学