摘要/Abstract

从中药南鹤虱（Fructus carotae）中分离纯化得到7个倍半萜类化合物，分别鉴定为7-ethoxy-4（15）-oppositen-1β-ol（1），11-乙酰氧基-8β-当归酰氧基-15-甲氧基-4α，5α-环氧愈创木烷-3-酮（2），11-乙酰氧基-8β-丙酰氧基-4-愈创木烯-3-酮（3），1-oxo-5α，7αH-eudesma-3-en-15-al（4），1β-hydroxy-4（15），7-eudesmadiene（5），1β-hydroxy-4（15），5E，10（14）-germacra-triene（6），1β-hydroxy-4（15），5-eudesmadiene（7）.其中化合物1和2为新的化合物，新化合物的结构进一步通过HR-ESIMS，1D NMR和2D NMR等光谱技术确定.
关键词: 伞形科, 南鹤虱, 愈创木烷型, 吉马烷型, 倍半萜类
Seven sesquterpenoids were obtained from the Chinese traditional medicine, Fructus carotae, and their structures were identified as 7-ethoxy-4(15)-oppositen-1β-ol (1), 11-acetoxy-8β-angeloyloxy-15-methoxy-4α,5α-epoxyarbutane-3-one (2), 11-acetoxy-8β-propionyl-4-guaien-3-one (3), 1-oxo-5α,7αH-eudesma-3-en-15-al (4), 1β-hydroxy-4(15),7-eudesmadiene (5), 1β-hydroxy-4(15),5E,10(14)-germacratriene (6) and 1β-hydroxy-4(15),5-eudesmadiene (7). Compounds 1 and 2 were new sesquterpenoid compounds, and their structures were determined by the analysis of HR-ESIMS, 1D NMR and 2D NMR.
Key words: apiaceae, fructus carotae, arbutane, eudesmane, sesquiterpenoids


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