报告题目：Molecular machinery based on DNA

报 告 人：Prof.Dr.Hendrik Dietz

报告时间：2017年10月10日 （星期二）下午2：00

报告地点：嘉定园区学术活动中心多功能厅

报告人简介：

CV　https://www.dietzlab.org/people/bio-dietz/

报告简介：　

Programmable self-assembly with DNA origami allows creating custom-shaped nanoscale objects. Through this capacity, DNA origami enables constructing custom instruments to perform precision measurements of molecular interactions and structure, with enhanced control over positioning, orientating and manipulating the molecules under study. In my presentation I will report about some of our progress toward constructing devices with greater complexity and more sophisticated functionalities (1,2). I will also discuss a series of measurements in which we used custom-made DNA nanotools to control distances between molecules with atomic precision (3), and to measure weak stacking forces between basepairs (4) and between pairs of nucleosomes (5) on the single particle level.