姓名:
翟万银性别:
男
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副研学历:
研究生
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200050通讯地址:
上海市定西路1295号


简历：
翟万银，男,博士，副研究员，2002年6月毕业于华东师范大学生命科学院生物化学与分子生物学专业，获硕士学位。2011年6月毕业于中国科学院上海微系统与信息技术研究所微电子与固体电子专业，获博士学位。2002年7月进入中国科学院上海硅酸盐研究所生物材料与组织工程研究中心。主要研究方向（1）生物材料的生物相容性研究和（2）心血管组织工程研究。主持完成上海市自然基金项目“用猪主动脉瓣及人骨髓干细胞构建人心脏瓣膜”，国家863项目“新型纳米药物载体靶向控释技术及其细胞生物学效应研究”子课题；作为主要完成人完成了国家自然基金项目“复合天然交联剂对动物心脏瓣膜交联作用的研究”、“天然交联剂原花青素对动物心脏瓣膜交联作用的研究”，目前承担国家自然基金面上项目“多酚对瓣膜弹性蛋白的交联及其在原位组织工程瓣膜支架制备中的应用研究”。联系方式:E-Mail:zhaiwy@mai;.sic.ac.cn;Tel:021-52412810(Off);021-52412801(Lab).发表论文：1.ZhaiW,ChangJ,LinK,WangJ,ZhaoQ,SunX.Crosslinkingofdecellularizedporcineheartvalvebyprocyanidins.Biomaterials,2006(27):3684-90.2.ZhaiW,ChangJ,LuX.Procyanidinscrosslinkedheartvalvematrix:Anti-calcificationeffect.JournalofBiomedicalMaterialsResearchPartB:ApplBiomater,2009(90B):913–921,.3.ZhaiW,LuX,ChangJ,ZhouY,ZhangH.Quercetincrosslinkedporcineheartvalvematrix:mechanicalproperty,stability,anti-calcificationandcytocompatibility.ActaBiomaterialia,.2010(6):389–395,.4.LüX,ZhaiW(co-Firstauthor),ZhouY,ZhouY,ZhangH,ChangJ.CrosslinkingeffectofNordihydroguaiareticacid(NDGA)ondecellularizedheartvalvescaffoldfortissueengineering,J.MaterSci:MaterMed,2010(21):473–480,.5.ZhaiW,JiaC,ZhaoH,XuY.Procyanidinsinhibittumorangiogenesisbycrosslinkingextracellularmatrix.ChinJCancerRes,2011,23(2):99-106.6.翟万银，吴蕾，贾春平，邵建波，徐元森.肿瘤微血管芯片的制备及其在通透性检测方面的应用.功能材料与器件学报,2011,.7.翟万银，周双雯，贾春萍，徐元森.藤黄酸抗肿瘤细胞生物学机制研究进展.细胞生物学学报,2009(31):481-485.8.ZhaiW,JiaC,LouX,JinQ,ZhaoJ,XuY.EnhancedantitumoractivityofIrinotecancombinedwithgambogicacidonNSCLC.21stIUBMBand12stFAOBMBInternationalCongressofBiochemistryandMolecularBiology,August2-7,2009,Shanghai,China.Abstract,D-3-017.p158.9.ZhaiW,LuH,ChenL,LinX,HuangY,DaiK,NaokiK,ChenG,ChangJ.Akermanite,asilicatebioceramic,stimulatesinvitroandinvivoangiogenesis.EuropeanCellandMaterialJournal,Underreview.10.ZhaiW,HeC,WuL,ZhouY,GuoL,ChenY,ChenH,ChangJ.Degradationofhollowmesoporoussilicananoparticles(HMSN)inhumanumbilicalveinendothelialcells.Nanomedicine:NanotechnologyBiologyMedicine,Underreview.11.ZhaiW,LuH,ChenL,LinX,HuangY,DaiK,NaokiK,ChenG,ChangJ.ImplicationsfromcomparativestudyonSi-containingceramicsandβ-TCP:thekeyroleofSiininvitrocellproliferation,osteo-differentiationandangiogenesis.Biomaterials,Submitted.12.ZhaiW,ChangJ.Procyanidins-crosslinkedporcineheartvalvematrix:mechanicalcharacteristics,stabilityandbiocompatibility.Oral,2006.11.13.ZhaiW,ChangJ.Crosslinking-decellularizedvalvularECMforbioprosthesesusingprocyanidins.ChineseBiomaterialsCongress,Chengdu,Oral,2010.4.14.何常亮,翟万银(共通讯作者)，张红霞,常江，张红峰，郭利民，陈航榕.中空介孔硅球对血管内皮细胞的细胞毒性.华东师范大学学报(自然科学板),2011(2):142-15115.XieY,ZhaiW,ChenL,ChangJ,ZhengXandDingC.Preparationandinvitroevaluationofplasma-sprayedMg2SiO4coatingontitaniumalloy.ActaBiomaterialia,2009(5):2331-233716.ZhangM,ZhaiW,LinK,PanH,LuW,ChangJ.Synthesis,in-vitrohydroxyapatiteformingability,andcytocompatibilityofstrontiumsilicatepowders.JournalofBiomedicalMaterialsResearchPartB(JBMR:B),AppliedBiomaterials,Inpress.17.WuC,ChangJ,ZhaiW,NiS,WangJ.Porousakermanitescaffoldsforbonetissueengineering:Preparation,characterization,andinvitrostudies.JournalofBiomedicalMaterialsResearchPartB:AppliedBiomaterials,2006(78B):47-55.18.ZhaoL,ChangJandZhaiW.PreparationandHL-7702cellfunctionalityoftitania/chitosancompositescaffolds.JMaterSci:MaterMed,2009(20):949–95719.ZhaoW,ChangJ,ZhaiW.Self-settingpropertiesandinvitrobioactivityofCa3SiO5/CaSO41/2H2ocompositecement.JournalofBiomedicalMaterialsResearchPartA,2008(85A):336-344.20.WuC,ChangJ,ZhaiWandNiS.Anovelbioactiveporousbredigite(Ca7MgSi4O16)scaffoldwithbiomimeticapatitelayerforbonetissueengineering.JournalofMaterialsScience:MaterialsinMedicine,2007(8):857-864.21.ZhaoL,ChangJ,ZhaiW.Experimentalresearchofpreparationandcharacterizationofchitosan/TiO2compositefilms.JournalofTissueEngineeringandReconstructiveSugery,.2008(4):196-199.22.DuRL,ChangJ,NiSY,ZhaiW,WangJY,Characterizationandinvitrobioactivityofzinc-containingbioactiveglassesandglass-ceramics,JBiomaterAppl,2006(20):341-360.23.NiS,ChangJ,ChouL,ZhaiW.Comparisonofosteoblast-likecellresponsestocalciumsilicateandtricalciumphosphateceramicsinvitro.JBiomedMaterResB,2007(80B):174-183.24.XieY,ZhengX,DingC,ZhaiW,ChangJ,andJiH.PreparationandCharacterizationofCaO-ZrO2-SiO2CoatingforPotentialApplicationinBiomedicine.JThermalSprayTechnol,2009(18):678-685,25.ZhaoW,ChangJ,WangJ,ZhaiWandWangZ.Invitrobioactivityofnoveltricalciumsilicateceramics.JournalofMaterialsScience:MaterialsinMedicine,2007(18):917-23.26.WangKW,ZhuYJ,ChenXY,ZhaiW,WangQ,ChenF,ChangJandDuanY-R.Flower-likehierarchicallynanostructuredhydroxyapatitehollowspheres:facilepreparationandapplicationinanticancerdrugcellulardelivery.Chemistry–AnAsianJournal,2010(5):2477–2482.27.NingC,DingD,DaiK,ZhaiWandChenL.TheeffectofZrcontentonthemicrostructure,mechanicalpropertiesandcellattachmentofTi–35Nb–xZralloys.Biomed.Mater,5045006doi:10.1088/1748-6041/5/4/04500628.ChenF,TangQL,ZhuYJ,WangKW,ZhangML,ZhaiW,ChangJ.Hydroxyapatitenanorods/poly(vinylpyrolidone)compositenanofibers,arraysandthree-dimensionalfabrics:Electrospunpreparationandtransformationtohydroxyapatitenanostructures.ActaBiomaterialia,2010(6):3013-3020.29.WanyinZhai,KailiLin,JiangChang.Studyoncrosslinkingofporcineheartvalvematrixusingprocyanidins.The8thAnnualMeetingofTissueEngineeringSocietyInternation.2005,22-25Oct.30.翟万银，常江，赵强，徐德明.组织工程心脏瓣膜研究进展，国外医学.生物医学工程学，2005，28（6）：321-325.31.翟万银,朱振勤,陈季武,王云丹,赵子寅,胡天喜.雷震子护康胶囊制剂抗氧化和对DNA损伤保护作用研究，发光学报2002，23（2）：191-196。32.朱振勤,翟万银,陈季武,夏晶,傅蓓蓓,谢萍,胡天喜.葡萄籽提取物抗氧化及对DNA保护作用研究，华东师范大学学报2003（1）：98-102。33.ZhuZQ,ZhaiWY,ChenJW,XiaJ,XieP.Effectsofgrapeseedprocyanidinscavengingfreeradicalsandprotectingculturedbovineaorticcellsfromoxidativedamage.Actabiochemicaetbiophysicasinica.2003,35:1046-7.34.LinKL,ZhaiWY,NiSY,ChangJ,ZengY,QianW,StudyofthemechanicalpropertyandinvitrobiocompatibilityofCaSiO3ceramics,CeramicsInternational,2005,31:323-326.35.WenyuanZhao,JunyingWang,WanyinZhai,ZhengWang,JiangChang.Theself-settingpropertiesandinvitrobioactivityoftricalciumsilicate.Biomaterials,2005,26(31):6113-6121.36.WuCT,ChangJ,ZhaiWY,Anovelhardystonitebioceramic:preparationandcharacteristics,CeramicsInternational,2005,31:27-3137.GouZ,ChangJ,ZhaiW,Preparationandcharacterizationofnovelbioactivedicalciumsilicateceramics.J.Eur.Ceram.Soc.,2005,25(9):1507-1514.38.ZhaoL,ChangJ,ZhaiW.EffectofdissolutionanddifferentcrystallographicphasephasesofTiO2onhepatocyteresponseinvitro.JournalofBiomaterialsApplications2005,19:237-252.39.GouZ,ChangJ,ZhaiW,WangJY,Studyontheself-settingpropertyandtheinvitrobioactivityofb-Ca2SiO4,JournalofBiomedicalMaterialsResearchPartB(JBMR:B),AppliedBiomaterials2005;37B:244-251,.40.WuCT,ChangJ,WangJY,NiSY,ZhaiWY,PreparationandCharacteristicsofaCalciumMagnesiumSilicate(Bredigite)BioactiveCeramic.Biomaterials,2005,26:2925-2931.专利：（1）常江，翟万银.发明名称“具有生物活性的人工生物瓣瓣膜的制备方法”.中国专利号：ZL200510110957.2。（2）常江，翟万银.发明名称“采用槲皮素交联制备人工生物心脏瓣膜材料的方法”.中国专利申请号：200810033498.6。（3）常江，翟万银.发明名称“一种可再细胞化的人工生物心脏瓣膜”.中国专利申请号：200910194839.2。职称：副高级

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