在岗研究生导师情况介绍
所系名称植生生态研究所
性别男
专业名称动物学
技术职务研究员
行政职务研究组长
Mail地址shengli@sippe.ac.cn
指导博士
生总数12指导硕士
生总数0已毕业学生通讯地址上海市枫林路300号
目前博士
生数3目前硕士
生数1目前在校生邮政编码200032
研究方向昆虫发育遗传学
研究工作我们以果蝇和家蚕为模式，整合生理、生化、细胞、分子、遗传和组学研究方法和手段，在细胞、器官和个体水平上研究昆虫变态发育。有三个相辅相成的研究方向（代表性成果）：
1、保幼激素和蜕皮激素的生理功能与信号传导(Liuetal.,2009Development;Tianetal.,2010JournalofMolecularCellBiology;Huangetal.,2011Development;Wangetal.,2012JournalofProteomeResearch)；
2、昆虫蜕皮变态和生长发育的激素与营养调控
脂肪体重建(Li,2010CellResearch;Wangetal.,2010JournalofMolecularCellBiology;Tianetal.,2013Autophagy)；
家蚕丝腺生长发育(Maetal.,2011CellResearch;Maetal.,2013JournalofProteomeResearch;Xiaetal.,2013AnnualReviewofEntomology)。
获奖情况2000年，中国科学院彭荫光奖学金一等奖
2006年，中国科学院“百人计划”入选；2007年，择优支持；2011年，终期评估“优秀”
2007年，上海市“浦江人才计划”；2009年，评审结果“优”
2010年，赛诺菲-安万特-中国科学院上海生命科学研究院优秀青年人才奖励基金
2011年，上海市“明治生命科学奖”优秀奖
2011年，国家自然科学基金委“国家杰出青年科学基金”
2012年，上海市“优秀学术带头人”
指导研究
生情况博士毕业生8+1名:胜振涛(美国博士后)、刘影(美国博士后)、马俐（植生所助研）、周顺（美国博士后）、王升（加拿大博士后）、郭恩恩（联培；瑞典博士后）、刘韩菡、何倩毓、王珈婉
出站博士后5名：田铃（副研）、谢永芳（副教授）、张建珍（教授）、刘洋、周顺
研究人员5名：田铃（博士、副研）、马俐（博士、助研）、刘淑敏（硕士、助研）、侯琪（实验员）、焦琳（实验员）
博士后1名：MuktadirS.Hossain
博士生3名：文狄、刘曦、贾强强
硕士生2名：袁冬伟、赵海港
联合培养研究生2名：李康（博士生）、马倩（硕士生）
个人简介1990.9-1994.7湖南师范大学生物系理学学士
1994.9-1997.7上海水产大学渔业学院农学硕士
1997.9-2000.7中国科学院上海昆虫研究所理学博士
2000.8-2001.7意大利UniversitaofBasilicatà生物系博士后
2001.8-2004.12美国IllinoisStateUniversity生物系博士后
2005.1-2006.8美国JohnsHopkinsUniversity医学院分子生物学和遗传学系博士后
2006.8-现在中国科学院上海生命科学研究院植物生理生态研究所研究员
中国科学院昆虫发育与进化生物学重点实验室副主任
中国昆虫学会理事
中国昆虫学会生理生化与分子生物学专业委员会理事
中国昆虫学会上海市昆虫学会理事
中国动物学会比较内分泌学专业委员会理事
JournalofInsectPhysiology编委
JournalofInsectScience编委
PLoSONE编委
FrontiersinExperimentalEndocrinology编委
Entomologia编委
应用昆虫学报编委
环境昆虫学报编委
EntomologicalResearch编委(2009-2012)
近期论文Principleinvestigator:
1.Xia,Q.*,Li,S.*,Feng,Q.*,2013.AdvancesinsilkwormstudiesacceleratedbygenomesequencingofBombyxmori.AnnualReviewofEntomology,aninvitedreview.
2.Hossain,M.S.,Liu,Y.,Li,K.,Tian,L.,Li,S.*,2013.20-Hydroxyecdysone-activatedFOXOupregulateslipasegenesthusinducinglipolysisintheBombyxfatbody.InsectBiochemistryandMolecularBiology,minorrevision.
3.Liu,H.,Jia,Q.,Li,S.*,2013.Balancingcrosstalkbetweensteroid-inducedautophagyandcaspaseactivityinthefatbodyduringDrosophilalarval-prepupaltransition.Autophagy,minorrevision.
4.Tian,L.,Ma,L.,Guo,E.,Deng,X.,Ma,S.,Xia,Q.,Cao,Y.,Li,S.*,2013.20-hydroxyecdysoneupregulatesAtggenestoinduceautophagyintheBombyxfatbody.Autophagy,http://dx.doi.org/10.4161/auto.24731.
5.Ma,L.,Liu,S.,Shi,M.,Chen,X-X.,Li,S.*,2013.Ras1CA-upregulatedbcpiinhibitiscathepsinactivitytopreventtissuedestructionoftheBombyxposteriorsilkgland.JournalofProteomeResearch,12:1924-1934.
6.Wang,S.,Wang,J.,Sun,Y.,Song,Q.,Li,S.*,2012.PKC-mediatedUSPphosphorylationatSer35modulates20-hydroxyecdysonesignalinginDrosophila.JournalofProteomeResearch,11:6187-6196.
7.Guo,E.,He,Q.,Liu,S.,Tian,L.,Sheng,Z.,Peng,Q.,GuanJ.,Shi,M.,Li,K.,Gilbert,L.I.,Wang,J.,Cao,Y.,Li,S.*,2012.METisrequiredforthemaximalactionof20-hydroxyecdysoneduringBombyxmetamorphosis.PLoSONE,7:e53256.
8.Zhu,J-Q.,Liu,S.,Ma,Y.,Zhang,J-Q.,Qi,H-S.,Wei,Z-J.,Yao,Q.,Zhang,W-Q.,Li,S.*,2012.ImprovementofpestresistanceintransgenictobaccoplantsexpressingdsRNAofaninsect-associatedgeneEcR.PLoSONE,7:e38572.
9.Abdou,M.,He,Q.,Wen,D.,Zyaan,O.,Wang,J.,Xu,J.,Baumann,A.A.,Joseph,J.,Wilson,T.G.,Li,S.*,Wang,J.,2011.DrosophilaMetandGcearefunctionallyredundantintransducingjuvenilehormoneaction.InsectBiochemistryandMolecularBiology,41:938-945.
10.Liu,S.,Zhou,S.,Tian,L.,Guo,E.,Luan,Y.,Zhang,J.,Li,S.*,2011.Genome-wideidentificationandcharacterizationofATP-bindingcassettetransportersinthesilkworm,Bombyxmori.BMCGenomics,12:491.
11.Ma,L.,Xu,H.,Zhu,J.,Ma,S.,Liu,Y.,Jiang,R-J.,Xia,Q,Li,S.*,2011.Ras1CAoverexpressionintheposteriorsilkglandimprovessilkyield.CellResearch,21:934-943.
(HighlightedbyBelles,X.2011CellResearch21:862-863)
(李胜，马俐，夏庆友，徐汉福，2010.一种提高蚕丝产量的转基因方法。专利申请号201010118072.8)
12.Huang,J.,Tian,L.,Abdou,M.,Wen,D.,Wang,Y.,Li,S.*,Wang,J.,2011.DPP-mediatedTGF-βsignalingregulatesjuvenilehormonebiosynthesisbyupregulatingexpressionofJHacidmethyltransferase.Development,138:2283-2291.
13.Gruntenko,N.E.,Wen,D.,Karpova,E.K.,Adonyeva,N.V.,Liu,Y.,He,Q.,Faddeeva,N.V.,Fomin,A.S.,Li,S.*,Rauschenbach,I.Y.,2010.Alteredjuvenilehormonemetabolism,reproductionandstressresistanceinDrosophilaadultswithgeneticablationofthecorpusallatumcells.InsectBiochemistryandMolecularBiology,40:891-897.
14.Zhou,S.,Zhou,Q.,Liu,Y.,Wang,S.,Wen,D.,He,Q.,Wang,W.,Bendena,W.G.,Li,S.*.，2010.TwoTorgenesinthesilkworm,Bombyxmori.InsectMolecularBiology,19:727-735.
15.Tian,L.,Guo,E.,Diao,Y.,Wang,S.,Liu,S.,Cao,Y.,Jiang,R-J.,Ling,E.,Li,S.*，2010.Developmentalregulationofglycolysisby20-hydroxyecdysoneandjuvenilehormoneinfatbodytissuesofthesilkworm,Bombyxmori.JournalofMolecularCellBiology,2:255–263.
16.Tian,L.,Guo,E.,Diao,Y.,Zhou,S.,Peng,Q.,Cao,Y.,Ling,E.,Li,S.*.,2010.Genome-wideregulationofinnateimmunitybyjuvenilehormoneand20-hydroxyecdysoneintheBombyxfatbody.BMCGenomics,11:549.
17.Li.S.*,2010.Identificationofiron-loadedferritinasanessentialmitogenforcellproliferationandpostembryonicdevelopmentinDrosophila.CellResearch,20:1148-1157.
18.Liu,Y.,Zhou,S.,Ma,L.,Tian,L.,Wang,S.,Sheng,Z.,Jiang,R-J.,Bendena,W.G.,Li,S.*,2010.Transcriptionalregulationoftheinsulinsignalingpathwaygenesbystarvationand20-hydroxyecdysoneintheBombyxfatbody.JournalofInsectPhysiology,56:1436-1444.
19.Wang,S.,Liu,S.,Liu,H.,Wang,J.,Zhou,S.,Liu,Y.,Jiang,R-J.,Bendena,W.G.,Li,S.*,2010.Theinsectsteroidhormone20-hydroxyecdysonereducesfoodconsumptionresultinginfatbodylipolysisduringmoltingandpupation.JournalofMolecularCellBiology,2:128-138.CoverStory
20.Liu,Y.,Sheng,Z.,Liu,H.,Wen,W.,He,Q.,Wang,S.,Shao,W.,Jiang,R-J.,An,S.,Sun,Y.,Bendena,W.G.,Wang,J.,Gilbert,L.I.,Wilson,T.G.,Song,Q.,Li,S.*,2009.JuvenilehormonecounteractsthebHLH-PAStranscriptionalfactorMETandGCEtopreventcaspase-dependentprogrammedcelldeathinDrosophila.Development,136:2015-2025.
21.Liu,Y.,Wang,S.,Liu,S.,Liu,H.,Jiang,R.J.,Li,S.*，2009.Hormonalandnutritionalregulationofinsectfatbodydevelopmentandfunction.ArchivesofInsectBiochemistryandPhysiology71:16-30.
22.Sheng,Z.T.,Ma,L.,Cao,M.X.,Jiang,R.J.,Li,S.*,2008.JuvenilehormoneacidmethyltransferaseisakeyregulatoryenzymeforjuvenilehormonesynthesisintheErisilkworm,Samiacynthicaricini.ArchivesofInsectBiochemistryandPhysiology69:143-154.
23.Sheng,Z.T.,Ma,L.,Cao,M.X,Li,S.*,Jiang,R.J.，2007.BiochemicalandmolecularcharacterizationoftheLepidopteraallatotropinandallatostatinfromtheErisilkworm,Samiacynthiaricin.InsectBiochemistryandMolecularBiology37:90-96.
Collaboration:
24.Valzania,L.,Romani,P.,Tian,L.,Li,S.,Cavaliere,V.,PennacchioF.,Gargiulo,G.,2013.ApolydnavirusANKproteinactsasvirulencefactorblockinghostdevelopment.PLoSPathogen,inrevision.
25.Rong,S.,Li,D.,Zhang,X.,Li,S.,Zhu,K.Y.,Guo,Y.,Ma,E.,Zhang,J.,2013.RNAinterferencetorevealrolesofβ-N-acetylglucosaminidasegeneduringmoltingprocessinLocustamigratoria.InsectScience,29:109-119.
26.Liu,X.,Zhang,H.,Li,S.,Zhu,K.Y.,Ma,E.,Zhang,J.,2012.Characterizationofamidgut-specificchitinsynthasegene(LmCHS2)responsibleforbiosynthesisofchitinofperitrophicmatrixinLocustamigratoria.InsectBiochemistryandMolecularBiology,42:902-910.
27.TheAutophagyConsortium,2012.Guidelinesfortheuseandinterpretationofassaysformonitoringautophagy.Autophagy,8:445-544.
28.Tian,L.,Liu,S.,Liu,H.,Li,S.,2012.20-hydroxyecdysoneupregulatesapoptoticgenesandinducesapoptosisintheBombyxfatbody.ArchivesofInsectBiochemistryandPhysiology,79:207-219.
29.An,S.,Dong,S.,Wang,Q.,Li,S.,Gilbert,L.I.,Stanley,D.,Song,Q.,2012.InsectneuropeptidebursiconhomodimersinduceinnateimmuneandstressgenesduringmoltingbyactivatingtheNF-κBfactorRelish.PLoSONE,7:e34510.
30.Gu,S.,Yeh,W.,Young,S.,Lin,P.,Li,S.,2012.TORsignalingisinvolvedinPTTH-stimulatedecdysteroidogenesisbyprothoracicglandsinthesilkworm,Bombyxmori.InsectBiochemistryandMolecularBiology,42:296-303.
31.Gruntenko,N.Е.,Karpova,E.K.,Bogomolova,E.V.,Adonyeva,N.V.,Menshanov,P.N.,Alekseev,A.A.,Romanova,I.V.,LiS.,Rauschenbach,I.Y.,2012.Geneticablationofthecorpusallatumcellsaffectsthestree-relatedhormonesmetabolisminDrosophila.JournalofInsectPhysiology,1:49-55.
32.Abdou,M.,Peng,C.,Huang,J.,Zyann,O.,Wang,S.,Li,S.,Wang,J.,2011.WntSignalingCross-talkswithJHSignalingbySuppressingMetandgceExpression.PLoSONE,6:e26772.
33.Chen,W-J.,Bu,Y.,Carapelli,A.,Dallai,R.,Li,S.,Yin,W-Y.,Luan,Y-X.,2011.ThemitochondrialgenomeofSinentomonerythranum(Arthropoda:Hexapoda:Protura):anexampleofhighlydivergentevolution.BMCEvolutionaryBiology,11:246.
34.Tian,L.,Ji,B-Z.,Liu,S-W.,He,C-L.,Jin,F.,Gao,J.,Stanley,D.,Li,S.,2010.AssessmentoftheJHbiosyntheticpathwaywithinthereproductivesystemandcorpusallatumintheadultlonghornedbeetleAprionagermari.ArchievesofInsectBiochemistryandPhysiology,75:275-286.
35.Tian,L.,Ji,B-Z.,Liu,S-W.,Jin,F.,Gao,J.,Li,S.2010.JuvenilehormoneIIIproducedinmaleaccessoryglandsofthelonghornedbeetle,Aprionagermari,istransferredtofemaleovariesduringcopulation.ArchivesofInsectBiochemistryandPhysiology,75:57-67.
36.Zhang,H.,Tian,L.,Tobe,S.,Xiong,Y.,Wang,S.,Lin,X.,Liu,Y.,Bendena,W.,Li,S.,Zhang,Y.Q.,2010.DrosophilaCG10527mutantsareresistanttojuvenilehormoneanditsanalogsmethopreneandmethylfarnesoate.BiochemicalandBiophysicalResearchCommunication,401:182-187.
37.Yang,Q.,Gong,Z-J.,Zhou,Y.,Yuan,J-Q.,Cheng,J.,Tian,L.,Li,S.,Lin,X-D.,Xu,R.,Zhu,Z-R.,Mao,C.,2010.RoleofDrosophilaalkalineceramidase(Dacer)inDrosophiladevelopmentandlongevity.CellularandMolecularLifeSciences,67:1477-1490.
PostdoctoraltrainingandPh.D.studies:
38.Li,S.,Friesen,J.A.,Holford,K.C.,Borst,D.W.,2010.Methylfarnesoatesynthesisinthelobstermandibularorgan:TherolesofHMG-CoAreductaseandfarnesoicacid-O-methyltransferase.ComparativeBiochemistryandPhysiologyA,155：49-55.
39.Hathaway,M.,Hatle,J.,Li,S.,Ding,X.,Tarry,T.,Hong,F.,Wood,H.,Borst,D.W.,2009.CharacterizationofhexamerinproteinsandtheirmRNAsintheadultlubbergrasshopper:theeffectsofnutritionandjuvenilehormoneontheirlevels.ComparativeBiochemistryandPhysiologyA154:323-332.
40.Li,S.*,ZhangQ.R.,XuW.H.,Schooley,D.A.,2005.Juvenilehormonediolkinase,acalcium-bindingproteinwithkinaseactivity,fromthesilkworm,Bombyxmori.InsectBiochemistryandMolecularBiology35:1235-1248.
41.Zhang,Q.R.,Xu,W.H.,Chen,F.S.,Li,S.*,2005.Molecularandbiochemicalcharacterizationofjuvenilehormoneepoxidehydrolasefromthesilkworm,Bombyxmori.InsectBiochemistryandMolecularBiology35:153-164.
42.Li,S.*,Ouyang,Y.C.,Ostrowski,E.,Borst,D.W.,2005.Allatotropinregulationofjuvenilehormonesynthesisbythecorporaallatafromthelubbergrasshopper,Romaleamicroptera.Peptides26:63-72.
43.Jiang,R.J.,Teng,H.,Koolman,J.,Li,S.,Cao,M.X.,2005.DevelopmentalchangesinhemolymphecdysteroidlevelandprothoracicotropichormoneactivityduringthefifthlarvalinstaroftheErisilkworm,Samiacynthiaricini.InsectScience12:241-248.
44.Li,S.,Friesen,J.A.,Fei,H.,Ding,X.,Borst,D.W.,2004.Thelobstermandibularorganproducessolubleandmembrane-bound3-hydroxy-3-methylglutaryl-coenzymeAreductases.BiochemicalJournal381:831-840.
45.Li,S.,Wagner,C.A.,Friesen,J.A.,Borst,D.W.,2003.3-hydroxy-3-methylglutaryl-coenzymeAreductaseinthelobstermandibularorgan:regulationbytheeyestalk.GeneralandComparativeEndocrinology134:147-155.
46.Li,S.,Falabella,Kuricanchan,I.,Vinson,S.B.,Borst,D.W.,Malva,C.,Pennacchio,F.,2003.Juvenilehormonesynthesis,metabolism,andresultinghaemolymphtitreinHeliothisvirescenslarvaeparasitizedbyToxoneuronnigriceps.JournalofInsectPhysiology49:1021-1030.
47.Li,S.,Falabella,P.,Giannantonio,S.,Fanti,P.,Battaglia,D.,Digilio,M.C.,Volkl,W.,Sloggett,J.J.,Weisser,W.,PennacchioF.,2002.Peaaphidclonalresistancetotheendophagousparasitoid,Aphidiuservi.JournalofInsectPhysiology48:971-980.
48.Li,S.,Jiang,R.J.,Cao,M.X.,2002.AllatotropicandallaostaticactivitiesinbrainextractsoftheErisilkworm,Samiacynthiaricini,andtheeffectsofManducasextaallatotropinandManducasextaallaostatinonjuvenilehormonebiosynthesisinvitro.PhysiologicalEntomology27:322-329.
49.Li,S.,Jiang,R.J.,Cao,M.X.2002.DevelopmentalchangesintheabilitytosynthesizejuvenilehormoneinvitrobycorporaallatafromtheErisilkworm,Samiacynthiaricini.EuropeanJournalofEntomology99:413-419.
