在岗研究生导师情况介绍
所系名称植生生态研究所
性别男
专业名称动物学
技术职务研究员
行政职务无
Mail地址erjunling@sippe.ac.cn
指导博士
生总数0指导硕士
生总数0已毕业学生通讯地址上海市枫林路300号
目前博士
生数4目前硕士
生数1目前在校生邮政编码200032
研究方向昆虫天然免疫和农业害虫的控制
研究工作Researchinterests:Insectshavenoadaptiveimmunitythatplaysaveryimportantroleintheimmunityofvertebrateanimalsandhumanbeings.Therefore,insectshavetodependontheso-calledinnateimmunitytofightagainsttheinvadedbacteria,fungiandparasitessoastoprotectthemtodevelopfluently.Mylabisinterestedinstudyingtheinsectinnateimmuneresponsesandfindingsomeimportanttargetgenesforthepestbiologicalcontrol.Wenowfocusonstudying:(1)Prophenoloxidase-activationcascadeanditsfunctiononmelanizationaroundforeigners;(2)Cellularimmunitylikecirculatinghemocytesinducedphagocytosisandencapsulationandtheirmechanism;(3)Theinteractionofbacteriaandinsecthostsinsidethebodyandmidgut;(4)Pestbiologicalcontrolthroughconstructingtransgenicplantsormicrobesusingthekeygenestoblocktheinsectinnateimmunity.
获奖情况
指导研究
生情况
个人简介Education:
Sep.1990-Sep.1994,AnhuiAgriculturalUniversity,P.R.China,Sericulture,B.S.;
Sep.1994-Jul.1997,AnhuiAgriculturalUniversity,P.R.China,Sericulture,M.S.;
Jul.1999-Mar.2003,ShinshuUniversity,Japan,Ph.D.
AcademicExperience:
Jul.1997-Jun.1999,AnhuiAgriculturalUniversity,P.R.China,Researcher;
Apr.2003-Mar.2004,ShinshuUniversity,Japan,COEpostdoctor;
Mar.2004-Aug.2007,UniversityofMissouri-KansasCity,USA,postdoctor;
Aug.2007-Jul.2008,UniversityofMissouri-Columbia,USA,postdoctor;
Jul.2008-present,Principalinvestigator,SIPPE,P.R.China.
近期论文1.QimiaoShao,BingYang,QiuyunXu,XuquanLi,ZhiqiangLu,ChengshuWang,YongpingHuang,KennethSöderhällandErjunLing*(2012)Hindgutinnateimmunityandregulationoffecalmicrobiotathroughmelanizationininsects.JournalofBiologicalChemistry287:14270-14279.
2.XuquanLi,MiaolianMa,FeiLiu,YangChen,AnruiLu,Qing-ZhiLing,JianyongLi,BrendaT.Beerntsen,Xiao-QiangYu,ChaoliangLiuandErjunLing*(2012)PropertiesofDrosophilamelanogasterprophenoloxidasesexpressedinEscherichiacoli.Developmental&ComparativeImmunology36(4):648-656.
3.FeiLiu,YangChen,BingYang,JingfangWang,QinPeng,QimiaoShao,XuanLi,BrendaT.Beerntsen,YechunXu,JianyongLi,Xiao-QiangYu,ErjunLing*(2012)DrosophilamelanogasterprophenoloxidasesrespondinconsistentlytoCu2+andhavedifferentactivityinvitro.Developmental&ComparativeImmunology36(3):619-628.
4.YupuDiao,YuminQi,YajunMa,AiXia,IgorSharakhov,XiaoguangChen,JimBiedler,ErjunLingandZhijianJakeTu(2011)Next-generationSequencingRevealsRecentHorizontalTransferofaDNATransposonbetweenDivergentMosquitoes.PLoSONE.2011,6(2):e16743
5.ZhixiangWang,AnruiLu,XuquanLi,QimiaoShao,BrendaT.Beerntsen,ChaoliangLiu,YajunMa,YaminHuang,HuaiminZhu,ErjunLing*(2011)AsystematicstudyonhemocyteidentificationandplasmaprophenoloxidasefromCulexpipiensquinquefasciatusatdifferentdevelopmentalstages.ExperimentalParasitology127:135–141.
6.ShanWu,XiaofengZhang,YongqiangHe,JiangbingShuai,XiaomeiChen,ErjunLing*(2010)ExpressionofantimicrobialpeptidegenesinBombyxmorigutmodulatedbyoralbacterialinfectionanddevelopment.Developmental&ComparativeImmunology34(11):1191-1198.
7.ShanWu,XiaofengZhang,XiaomeiChen,PingshengCao,ErjunLing*(2010)BmToll9,anArthropodsconservativeToll,isprobablyinvolvedinthelocalgutimmuneresponseinthesilkworm,Bombyxmori.Developmental&ComparativeImmunology34(2):93-96.
8.ChenglongWang,ZhixiangWang,Qing-zhiLing,MichaelM.Kariuki,KenjiKiguchi,ErjunLing*(2010)Physiologicalfunctionsofhemocytesnewlyemergedfromtheculturedhematopoieticorgansinthesilkworm,Bombyxmori.InsectScience17:7-20.
9.Xiang-JunRao#,ErjunLing#andXiao-QiangYu(2010)TheroleoflysozymeintheprophenoloxidaseactivationsystemofManducasexta:Aninvitroapproach.Developmental&ComparativeImmunology(#Equalcontribution)34(3):264-271.
10.LingTian,EnenGuo,YupuDiao,ShunZhou,QinPeng,YangCao,ErjunLing,ShengLi(2010)Genome-wideregulationofinnateimmunitybyjuvenilehormoneand20-hydroxyecdysoneintheBombyxfatbody.BMCGenomics11:549.
11.LingTian,EnenGuo,ShengWang,ShuminLiu,Rong-JingJiang,YangCao,ErjunLingandShengLi(2010)Developmentalregulationofglycolysisby20-hydroxyecdysoneandjuvenilehormoneinfatbodytissuesofthesilkworm,Bombyxmori.JournalofMolecularCellBiology2(5):255-263.
12.FeiLiu,ErjunLing,ShanWu(2009)Geneexpressionprofilingduringearlyresponsetoinjuryandmicrobialchallengesinthesilkworm,Bombyxmori.ArchivesofInsectBiochemistryandPhysiology72(1):16-33.
13.YangChen,ErjunLing,ZhihuiWeng(2009)FunctionalcharacterizationofPGRP-LC1ofAnophelesgambiaethroughdeletionandRNAinterference.InsectScience16:443-453.
14.Qing-zhiLing,ChenglongWang,MichaelM.Kariuki,KenjiKiguchiandErjunLing（2009）Reexaminationoftheroleofhematopoieticorgansonthehematopoiesisinthesilkworm,Bombyxmori.AfricanJournalofBiotechnology8(15):3658-3665.
15.ErjunLing,Xiang-junRao,Jing-qunAoandXiao-QiangYu(2009)PurificationandcharacterizationofasmallcationicpeptidefromthetobaccohornwormManducasexta.InsectBiochemistryandMolecularBiology39(4):263-271.
16.ErjunLing,Jing-qunAoandXiao-QiangYu(2008)NuclearTranslocationofImmulectin-3StimulatesHemocyteProliferation.MolecularImmunology45:2598-2606.
17.Jing-qunAo,ErjunLingandXiao-QiangYu(2008)ATollReceptorfromManducasextaisinResponsetoEscherichiacoliInfectionMolecularImmunology.MolecularImmunology45:543-552.
18.Jing-qunAo,ErjunLing,Xiang-junRaoandXiao-QiangYu(2008)AnovelMLproteinfromManducasextamayfunctionasakeyaccessoryproteinforlipopolysaccharidesignaling.MolecularImmunology45:2772-2781.
19.Jing-qunAo,ErjunLingandXiao-QiangYu(2007)DrosophilaC-typelectinsenhancecellularencapsulation.MolecularImmunology44:2541-2548.
20.ErjunLingandXiao-QiangYu(2006)Cellularencapsulationandmelanizationareenhancedbyimmulectins,patternrecognitionreceptorsfromthetobaccohornwormManducasexta.Developmental&ComparativeImmunology30:289-299.
21.ErjunLingandXiao-QiangYu(2006)HemocytesfromthetobaccohornwormManducasextahavedistinctfunctionsinphagocytosisofforeignparticlesandselfdeadcells.Developmental&ComparativeImmunology30:301-309.
22.ErjunLing*,KojiShirai,RensukeKanekatsu,KenjiKiguchi,YasuhikoKobayashi,TomooFunayamaandHiroshiWatanabe(2006)Contributionofcirculatinghemocytestotheregenerationofheavyionbeams(12C5+)irradiatedhematopoieticorgansinthesilkworm,Bombyxmori,throughthewayofphagocytosisofinjuredcellsafterinvasion.Developmental&ComparativeImmunology30:531-543.
23.Xiao-QiangYu,ErjunLing,MilesE.TracyandYifeiZhu(2006)Immulectin-4fromthetobaccohornwormManducasextabindstolipopolysaccharideandlipoteichoicacid.InsectMolecularBiology15:119-128.
24.ErjunLing*,KojiShirai,RensukeKanehatsuandKenjiKiguchi(2005)Reexaminationofphenoloxidaseinlarvalcirculatinghemocytesofthesilkworm,Bombyxmori.TissueandCell37:101-107.
25.ErjunLing*,KojiShirai,RensukeKanekatsuandKenjiKiguchi(2005)Hemocytedifferentiationinthehematopoieticorgansofthesilkworm,Bombyxmori:prohemocyteshavethefunctionofphagocytosis.CellandTissueResearch320:535-543.
26.ErjunLingandXiao-QiangYu(2005)ProphenoloxidasebindstothesurfaceofhemocytesandisinvolvedinhemocytemelanizationinManducasexta.InsectBiochemistryandMolecularBiology35:1356-1366.
27.Xiao-QiangYu,MilesE.Tracy,ErjunLing,ScholzFRandTrenczekT(2005)AnovelC-typeimmulectin-3fromManducasextaistranslocatedfromhemolymphintothecytoplasmofhemocytes.InsectBiochemistryandMolecularBiology35:285-295.
28.ErjunLing,KanaFukamoto,ShiqingXu,KojiShirai,RensukeKanekatsu,YasuhikoKobayashi,Zhen-LiTu,TomooFunayama,HiroshiWatanabeandKenjiKiguchi(2003)Regenerationofhemopoieticorgansinthesilkworm,Bombyxmori,afterlocallytargetedirradiationwithheavyionbeams.JournalofInsectBiotechnologyandSericology72:95-100.
29.ErjunLing,KojiShirai,RensukeKanekatsu,YasuhikoKobayashi,Zhen-LiTu,TomooFunayama,HiroshiWatanabeandKenjiKiguchi(2003)Whydosehemocytedensityriseatthewanderingstageinthesilkworm,Bombyxmori?JournalofInsectBiotechnologyandSericology72:101-109.
26.ErjunLing*,KojiShirai,RensukeKanekatsuandKenjiKiguchi(2003)Classificationoflarvalcirculatinghemocytesofthesilkworm,Bombyxmori,byacridineorangeandpropidiumiodidestaining.HistochemistryandCellBiology120:505-511.
