在岗研究生导师情况介绍
所系名称健康科学研究所
性别男
专业名称生物化学与分子生物学
技术职务研究员
行政职务1
Mail地址gqchen@sibs.ac.cn
指导博士
生总数15指导硕士
生总数6已毕业学生通讯地址上海重庆南路225号
目前博士
生数6目前硕士
生数3目前在校生邮政编码200025
研究方向肿瘤(白血病)细胞分化与凋亡生物学及其治疗学基础研究
研究工作在建立和完善蛋白质组学技术，尤其是蛋白质相互作用组学技术平台的基础上，建立前肿瘤干细胞研究、非编码RNA研究和化学生物学研究技术体系，开展如下研究：①白血病细胞分化与凋亡的重要蛋白质相互作用网络及其调控机制的研究，以期获得白血病发生发展过程中关键的调控信息，在白血病的发病学领域提出新的观点，并为白血病的治疗学研究提出新的线索。②以现有药物或活性化合物，特别是中草药有效成分或活性天然产物为探针，开展肿瘤细胞凋亡和分化机制的化学生物学研究，寻找与其特异结合的蛋白质或其它生物大分子，为创新药物的靶标筛选和验证奠定坚实的基础。③非编码RNA的调控及其在细胞分化和凋亡中的作用研究。将在现有研究工作的基础上，探索本学科发现的重要细胞分化相关蛋白对非编码RNA的潜在调控作用，继而发现可能参与细胞分化的重要RNA，并研究其分子机制。④建立肿瘤干细胞实验技术体系，探索针对肿瘤干细胞的先导化合物的研究。
获奖情况上海自然科学一等奖.2008
中华医学科技一等奖，2005
上海科技进步一等奖，2005
上海医学科技一等奖，2005
全国先进工作者(劳动模范),2005
上海市劳动模范，2004
上海市科技英才，2004
上海市自然科学“牡丹”奖，2004
上海医学科技一等奖，2004
教育部自然科学提名一等奖，2004
上海市优秀学科带头人，2003（上海市科委）
上海优秀留学回国人员，2003（上海市人民政府）
中国青年科技奖，2003（中国科协）
新世纪百千万人才工程首批国家级人选,2003(国家人事部等)
上海市“十大杰出青年”，2002（上海市团委等）
国家自然科学二等奖（第四完成人），2000（国务院）
杜邦科技创新奖（第四完成人），2000（国家科技部）
国务院特殊津贴，2000（国务院）
上海市优秀青年教师，1999（上海市教委）
上海市卫生系统杰出青年人才“银蛇奖”，1999（上海市卫生局）
上海市卫生局行政记大功一次，1999（上海市卫生局）
明治乳业生命科学奖，1998（日本明治乳业公司）
上海市科技进步一等奖（第三完成人），1997（上海市人民政府）
上海市科协科技论文二等奖，1997（上海市科协）
上海市优秀青年教师，1997（上海市教委）
指导研究
生情况目前在学硕士生：3人；博士生人数：6人
个人简介1985~1988: 上海第二医科大学攻读病理生理学专业硕士研究生
988~1993: 湖南衡阳医学院病理生理教研室，91年12月获讲师任职资格
1993~1996: 上海第二医科大学博士研究生(内科血液学专业)
1996.7~1999.10:上海第二医科大学附属瑞金医院血液学研究所研究室主任，副研究员，研究员。
1997: 法国巴黎Saint-Louis医院访问学者
1998: 兼任上海第二医科大学生物学教研室副主任
1999: 《癌症》杂志副主编，常务编委
1999~2001:美国Mount-Saint医学院visitingassistant professor
2000:上海市青年联合会委员
2001~今:中国科学院上海生命科学研究院“百人”计划课题组组长，
2002-2009:上海第二医科大学(现上海交通大学医学院)病理生理学教研室主任
2005~至今:细胞分化与凋亡教育部重点实验室主任
近期论文1)WuSF,HuangY,HouJK,YuanTT,ZhouCX,ZhangJ,ChenGQ.ThedownregulationofonzinexpressionbyPKC-ERK2signalinganditspotentialroleinAMLcelldifferentiation.Leukemia,2009，inpress
2)AzouzA,WuYL,HillionJ,IlonaTarkanyiI,AradiJ,LanotteM,ChenGQ,ChehnaM,KARNIGUIANA,SEGAL-BENDIRDJIANE.EpigeneticplasticityofhTERTgenepromoterdeterminesretinoidcapacitytorepresstelomeraseactivityinmaturation-resistantacutepromyelocyticleukemiacells.Leukemia,2009,inpress
3)ShenSM,YuY,WuYL,ChengJK,WangLS,ChenGQ.Down-regulationofANP32B,anovelsubstrateofcaspase-3,enhancescaspase-3activationandapoptosisinductioninmyeloidleukemiccells..Carcinogenesis.2009Dec16.[Epubaheadofprint]
4)ChenGQ,ZhangJ,ZhaoQ.Activecompounds-baseddiscoveriesaboutthedifferentiationandapoptosisofleukemiccells.ChineseScienceBulletin.2009;54(22):4094-4101
5)DuanXF,WuYL,XuHZ,ZhaoM,ZhuangHY,WangXD,YanH,ChenGQ.Synergisticmitosis-arrestingeffectsofarsenictrioxideandpaclitaxelonhumanmalignantlymphocytes.ChemBiolInteract.2010;183:222-230
6)GaoFH,WuYL,ZhaoM,LiuCX,WangLS,ChenGQ.ProteinKinaseC-deltamediatesdown-regulationofheterogeneousnuclearribonucleoproteinKprotein:Involvementinapoptosisinduction.ExpCellRes.2009;315(19):3250-8.
7)HeF,XiaoWL,PuJX,WuYL,ZhangHB,LiXN,ZhaoY,YangLB,ChenGQ,SunHD.Cytotoxicent-kauranediterpenoidsfromIsodonsinuolata.Phytochemistry.2009;70(11-12):1462-6.Epub2009Aug25.
8)YueF,WangLS,XiaL,WangXL,FengB,LuAG,ChenGQ,ZhengMH.ModulatedT-complexprotein1zetaandpeptidyl-prolylcis-transisomeraseBaretwonovelindicatorsforevaluatinglymphnodemetastasisincolorectalcancer:evidencefromproteomicsandbioinformatics.ProteomicsClinAppl,2009，3(10):1225-1235
9)XiongH,ChenZF,LiangQC,DuW,ChenHM,SuWY,ChenGQ,HanZG,FangJY.InhibitionofDNAmethyltransferaseinducesG2cellcyclearrestandapoptosisinhumancolorectalcancercellsviainhibitionofJAK2/STAT3/STAT5signaling.JCellMolMed.2009Jan16.[Epubaheadofprint]PMID:19175468[PubMed-assuppliedbypublisher]
10)LiaoSH,ZhaoXY,HanYH,ZhangJ,WangLS,XiaL,ZhaoKW,ZhengY,GuoM,ChenGQ.Proteomics-basedidentificationoftwonoveldirecttargetsofhypoxia-induciblefactor-1andtheirpotentialrolesinmigration/invasionofcancercells.Proteomics.2009Jul27;9(15):3901-3912
11)ZhangJ,ChenGQ.Hypoxia-HIF-1alpha-C/EBPalpha/Runx1signalinginleukemiccelldifferentiation.Pathophysiology.200916:297-303
12)ZhangYJ,DaiQ,SunDF,XiongH,TianXQ,GaoFH,XuMH,ChenGQ,HanZG,FangJY.mTORSignalingPathwayIsaTargetfortheTreatmentofColorectalCancer.AnnSurgOncol.2009Sep;16(9):2617-28
13)ZhaoM,DuanX-F,ZhaoX-Y,ZhangB,LuY,LiuW,ChengJK,ChenGQ.ProteinkinaseCδstimulatesproteasome-dependentdegradationofC/EBPαduringapoptosisinductionofleukemicCells.PLoSONE.2009;4(8):e6552.
14)ZhaoY,PuJX,HuangSX,DingLS,WuYL,LiX,YangLB,XiaoWL,ChenGQ,SunHD.ent-KauraneDiterpenoidsfromIsodonpharicus.JNatProd.2009Jun26;72(6):988-993
15)ChenS,HanYH,ZhengY,ZhaoM,YanH,ZhaoQ,ChenGQ,LiD.NDRG1contributestoretinoicacid-induceddifferentiationofleukemiccells.LeukRes.2009Aug;33(8):1108-13PMID:19046768[PubMed-assuppliedbypublisher]
16)ZhaoY,PuJX,HuangSX,WuYL,YangLB,XiaoWL,HanQB,ChenGQ,SunHD.ent-KauranediterpenoidsfromIsodonscoparius..JNatProd.2009Jan;72(1):125-9.
17)YuanTT,HuangY,ZhouCX,YuY,WangLS,ChenGQ.NucleartranslocationofdihydrofolatereductaseisanovelandspecificmarkerofDNAdamage-inducedapoptosis.Apoptosis.2009May;14(5):699-710PMID:19360472[PubMed-assuppliedbypublisher]
18)ZhengY,WangLS,XiaL,HanYH,LiaoSH,WangXL,ChengJK,ChenGQ.NDRG1isdown-regulatedintheearlyapoptoticeventinducedbycamptothecinanalogs:ThepotentialroleinproteolyticactivationofPKCdeltaandapoptosis.Proteomics.2009Mar25;9(8):2064-2075PMID:19322780[PubMed-assuppliedbypublisher]
19)MengC,JinX,XiaL,ShenSM,WangXL,CaiJ,ChenGQ,WangLS,FangNY.AlterationsofMitochondrialEnzymesContributetoCardiacHypertrophybeforeHypertensionDevelopmentinSpontaneouslyHypertensiveRats.JProteomeRes.2009May1;8(5):2463-2475.PMID:19265432[PubMed-assuppliedbypublisher]
20)ZhaoM,DuanXF,WenDH,ChenGQ.PU.1,anovelcapase-3substrate,partiallycontributestochemotherapeuticagents-inducedapoptosisinleukemiccells.BiochemBiophysResCommun.2009May8;382(3):508-13.Epub2009Mar10.]PMID:19281794[PubMed-assuppliedbypublisher]
21)YuH,MengY,WangLS,JinX,GaoLF,ZhouL,JiK,LiY,ZhaoLJ,ChenGQ,ZhaoXJ,YangB.DifferentialproteinexpressioninheartinUT-Bnullmicewithcardiacconductiondefects.Proteomics.2009Feb;9(3):504-11.PMID:19132680[PubMed-inprocess]
22)ZhangN,ZhangH,XiaL,ZhengY,YuY,ZhuY,ChenGQ,DiW.NSC606985inducesapoptosis,exertssynergisticeffectswithcisplatin,andinhibitshypoxia-stabilizedHIF-1alphaproteininhumanovariancancercells.CancerLett.2009Jun18;278(2):139-44.PMID:19339107[PubMed-inprocess]
23)ChenLY,PanWW,ChenM,LiJD,LiuW,ChenGQ,HuangS,PapadimosTJ,PanZK.SynergisticinductionofinflammationbybacterialproductslipopolysaccharideandfMLP:animportantmicrobialpathogenicmechanism..JImmunol.2009Feb15;182(4):2518-24.
24)ZhangJ,SongLP,HuangY,ZhaoQ,ZhaoKW,ChenGQ.Accumulationofhypoxia-induciblefactor-1{alpha}proteinanditsroleinthedifferentiationofmyeloidleukemiccellsinducedbyall-transretinoicacid.Haematologica.2008Oct;93(10):1480-7.PMID:18728026[PubMed-assuppliedbypublisher]
25)JinX,WangLS,XiaL,ZhengY,MengC,YuY,ChenGQ,FangNY.Hyper-phosphorylationofalpha-enolaseinhypertrophiedleftventricleofspontaneouslyhypertensiverat.BiochemBiophysResCommun.2008Jul11;371(4):804-9.PMID:18468517[PubMed-indexedforMEDLINE]
26)XuYB,ZhangJ,Segal-BendirdjianE,WuYL,ChenGQ.Hypoxia-induciblefactor-1a-independentdecreaseoftelomeraseplaysakeyroleincobaltchloride-inducedapoptosisofmyeloidleukemiccells.TheOpenHematologyJournal.2008;2:63-69
27)TanC,CaiLQ,WuW,QiaoY,Imperato-McGinleyJ,ChenGQ,ZhuYS.NSC606985,anovelcamptothecinanalog,inducesapoptosisandgrowtharrestinprostatetumorcells.CancerChemotherPharmacol.2009Jan;63(2):303-12.Epub2008Mar292008Mar29;[Epubaheadofprint
28)LuY,PengZG,YuanTT,YinQQ,XiaL,ChenGQ.Multi-sitescleavageofleukemogenicAML1-ETOfusionproteinbycaspase-3anditscontributiontoincreasedapoptoticsensitivity.Leukemia.2008;22:378-386PMID:17989718[PubMed-assuppliedbypublisher]
29)PengZG,ZhouMY,HuangY,QiuJH,WangLS,LiaoSH,DongS,ChenGQ.PhysicalandfunctionalinteractionofRunt-relatedprotein1withhypoxia-induciblefactor-1alpha.Oncogene.200827:839-847.PMID:17684492
30)SongLP,ZhangJ,WuSF,HuangY,ZhaoQ,CaoJP,WuYL,WangLS,ChenGQ.Hypoxia-induciblefactor-1alpha-induceddifferentiationofmyeloidleukemiccellsisitstranscriptionalactivityindependent.Oncogene.2008;27,519–527PMID:17637739
31)YangL,JiangY,WuSF,ZhouMY,WuYL,ChenGQ.CCAAT/enhancerbindingprotein{alpha}antagonizestranscriptionalactivityofhypoxiainduciblefactor-1{alpha}withdirectprotein-proteininteraction.Carcinogenesis.2008Feb;29(2):291-8PMID:18024476
32)HuangY,QiuJ,ChenGQ,DongS.Coiled-coildomainofPMLisessentialfortheaberrantdynamicsofPML-RARalpha,resultinginsequestrationanddecreasedmobilityofSMRT.BiochemBiophysResCommun.2008Jan11;365(2):258-65.PMID:17991421[PubMed-indexedforMEDLINE]
33)WangS,ZhengY,YuY,XiaL,ChenGQ,YangYZ,WangLS.Phosphorylationofbeta-actinbyproteinkinaseC-deltaincamptothecinanalog-inducedleukemiccellapoptosis.ActaPharmacolSin.2008Jan;29(1):135-42.PMID:18158875[PubMed-inprocess]
34)YanH,WangYC,LiD,WangY,LiuW,WuYL,ChenGQ.Arsenictrioxideandproteasomeinhibitorbortezomibsynergisticallyinduceapoptosisinleukemiccells:theroleofproteinkinaseCdelta.Leukemia.2007Jul;21(7):1488-95.PMID:17495969
35)YuY,WangLS,ShenSM,XiaL,ZhangL,ZhuYS,ChenGQ.SubcellularProteomeAnalysisofCamptothecinAnalogueNSC606985-TreatedAcuteMyeloidLeukemicCells.JProteomeRes.2007Sep7;6(9):3808-3818.PMID:17655343
36)QiuJ,HuangY,ChenGQ,ChenZ,TweardyDJ,DongS.Aberrantchromatinremodelingbyretinoicacidreceptor{alpha}fusionproteinsassessedatthesingle-celllevel.MolBiolCell.2007Oct;18(10):3941-51PMID:17671166
37)XuM,LiD,LuY,ChenGQ.LeukemogenicAML1-ETOfusionproteinincreasescarcinogen-DNAadductformationwithupregulatedexpressionofcytochromeP450-1A1gene.ExpHematol.2007Aug;35(8):1249-1255.PMID:17560011
38)GaoFH,WangQ,WuYL,LiX,ZhaoKW,ChenGQ.c-JunN-terminalkinasemediatesAML1-ETOprotein-inducedconnexin-43expression.BiochemBiophysResCommun.2007May4;356(2):505-11.PMID:17367753
39)LiuW,ZhuYS,GuoM,YuY,ChenGQ.TherapeuticefficacyofNSC606985,anovelcamptothecinanalog,inamousemodelofacutepromyelocyticleukemia.LeukRes.2007Nov;31(11):1565-1574.PMID:17428537
40)ShenWW,WuJ,CaiL,LiuBY,GaoY,ChenGQ,FuGH.Expressionofanionexchanger1sequestratesp16inthecytoplasmingastricandcolonicadenocarcinoma.Neoplasia.2007Oct;9(10):812-9.PMID:17971901
41)WangY,WuSF,ChenGQ,FuGH.EffectofblockdeletionsintheC-terminusonthefunctionalexpressionofhumananionexchanger1(AE1).MolMembrBiol.2007Jan-Feb;24(1):65-73.PMID:17453414
42)ChenGQ,WangLS,WuYL,YuY.Leukemia,aneffectivemodelforchemicalbiologyandtargettherapy.ActaPharmacolSin.2007Sep;28(9):1316-1324.PMID:17723165
43)ZhangL,WangLS,XuY,XiaL,ChenWL,ZhengY,ChenGQ.ComparativeproteomicanalysisofhumanleukemiccellswithandwithoutinducibleexpressionofleukemogenicAML1-ETOprotein.ChinJPhysiol.2006Aug31;49(4):182-91.PMID:17058450
44)XiaoS,LiD,ZhuHQ,SongMG,PanXR,JiaPM,PengLL,DouAX,ChenGQ,ChenSJ,ChenZ,TongJH.RIG-Gasakeymediatoroftheantiproliferativeactivityofinterferon-relatedpathwaysthroughenhancingp21andp27proteins.ProcNatlAcadSciUSA.2006Oct31;103(44):16448-53.PMID:17050680
45)RenH,CaoY,ZhaoQ,LiJ,ZhouC,LiaoL,JiaM,ZhaoQ,CaiH,HanZC,YangR,ChenGQ,ZhaoRC.Proliferationanddifferentiationofbonemarrowstromalcellsunderhypoxicconditions.BiochemBiophysResCommun.2006Aug18;347(1):12-21.PMID:16814746
46)PanXY,ChenGQ,CaiL,BuscemiS,FuGH.Anionexchanger2mediatestheactionofarsenictrioxide.BrJHaematol.2006Sep;134(5):491-9.PMID:17018029
47)LiX,XuYB,WangQ,LuY,ZhengY,WangYC,LubbertM,ZhaoKW,ChenGQ.LeukemogenicAML1-ETOfusionproteinupregulatesexpressionofconnexin43:theroleinAML1-ETO-inducedgrowtharrestinleukemiccells.JCellPhysiol.2006Sep;208(3):594-601.PMID:16741927
48)HuangY,ZhaoQ,ZhouCX,GuZM,LiD,XuHZ,WiedmerT,SimsPJ,ZhaoKW,ChenGQ.Antileukemicrolesofhumanphospholipidscramblase1gene,evidencefrominduciblePLSCR1-expressingleukemiccells.Oncogene.2006Oct26;25(50):6618-27.PMID:16702944
49)HanYH,XiaL,SongLP,ZhengY,ChenWL,ZhangL,HuangY,ChenGQ,WangLS.Comparativeproteomicanalysisofhypoxia-treatedanduntreatedhumanleukemicU937cells.Proteomics.2006Jun;6(11):3262-74.PMID:16622835
50)LuY,XuYB,YuanTT,SongMG,LubbertM,FliegaufM,ChenGQ.InducibleexpressionofAML1-ETOfusionproteinendowsleukemiccellswithsusceptibilitytoextrinsicandintrinsicapoptosis.Leukemia.2006Jun;20(6):987-93.PMID:16598301
51)JinX,XiaL,WangLS,ShiJZ,ZhengY,ChenWL,ZhangL,LiuZG,ChenGQ,FangNY.Differentialproteinexpressioninhypertrophicheartwithandwithouthypertensioninspontaneouslyhypertensiverats.Proteomics.2006Mar;6(6):1948-56.PMID:16485256
52)WuYL,DudognonC,NguyenE,HillionJ,PendinoF,TarkanyiI,AradiJ,LanotteM,TongJH,ChenGQ,Segal-BendirdjianE.Immunodetectionofhumantelomerasereverse-transcriptase(hTERT)re-appraised:nucleolinandtelomerasecrosspaths.JCellSci.2006Jul1;119(Pt13):2797-806.
53)GuoM,SongLP,JiangY,LiuW,YuY,ChenGQ.Hypoxia-mimeticagentsdesferrioxamineandcobaltchlorideinduceleukemiccellapoptosisthroughdifferenthypoxia-induciblefactor-1alphaindependentmechanisms.Apoptosis.2006Jan;11(1):67-77.PMID:16374551
54)LiuW,GuoM,XuYB,LiD,ZhouZN,WuYL,ChenZ,KoganSC,ChenGQ.Inductionoftumorarrestanddifferentiationwithprolongedsurvivalbyintermittenthypoxiainamousemodelofacutemyeloidleukemia.Blood.2006Jan15;107(2):698-707.PMID:16166593
55)YanH,PengZG,WuYL,JiangY,YuY,HuangY,ZhuYS,ZhaoQ,ChenGQ.Hypoxia-simulatingagentsandselectivestimulationofarsenictrioxide-inducedgrowtharrestandcelldifferentiationinacutepromyelocyticleukemiccells.Haematologica.2005Dec;90(12):1607-16.PMID:16330433
56)ZhaoKW,LiD,ZhaoQ,HuangY,SilvermanRH,SimsPJ,ChenGQ.Interferon-alpha-inducedexpressionofphospholipidscramblase1throughSTAT1requiresthesequentialactivationofproteinkinaseCdeltaandJNK.JBiolChem.2005Dec30;280(52):42707-14.PMID:16260419
57)FuGH,WangY,XiYH,GuoZW,LiuXB,BaiSZ,YangBF,ChenGQ.As2O3enhancestheaniontransportactivityofband3andtheactionisrelatedwiththeC-terminal16residuesoftheprotein(dagger).JDrugTarget.2005May;13(4):235-43.PMID:16051535
58)LiZ,LiuQ,SongM,ZhengY,NanP,CaoY,ChenGQ,LiY,ZhongY.Detectingcorrelationbetweensequenceandexpressiondivergencesinacomparativeanalysisofhumanserpingenes.Biosystems.2005Dec;82(3):226-34.PMID:16112386
59)XueZH,JiangY,YuY,WangLS,ChenGQ,ZhaoQ.Metavanadatesuppressesdesferrioxamine-inducedleukemiccelldifferentiationwithreducedhypoxia-induciblefactor-1alphaprotein.BiochemBiophysResCommun.2005Jul15;332(4):1140-5.PMID:15935329
60)JiangY,XueZH,ShenWZ,DuKM,YanH,YuY,PengZG,SongMG,TongJH,ChenZ,HuangY,LubbertM,ChenGQ.Desferrioxamineinducesleukemiccelldifferentiationpotentiallybyhypoxia-induciblefactor-1alphathataugmentstranscriptionalactivityofCCAAT/enhancer-bindingprotein-alpha.Leukemia.2005Jul;19(7):1239-47.PMID:15902299
61)YuY,ChenS,WangLS,ChenWL,GuoWJ,YanH,ZhangWH,PengCH,ZhangSD,LiHW,ChenGQ.Predictionofpancreaticcancerbyserumbiomarkersusingsurface-enhancedlaserdesorption/ionization-baseddecisiontreeclassification.Oncology.2005;68(1):79-86.PMID:15864000
62)FuGH,WangY,XiYH,ShenWW,PanXY,ShenWZ,JiangXS,ChenGQ.Directinteractionandcooperativeroleoftumorsuppressorp16withband3(AE1).FEBSLett.2005Apr11;579(10):2105-10.PMID:15811326
63)SongMG,GaoSM,DuKM,XuM,YuY,ZhouYH,WangQ,ChenZ,ZhuYS,ChenGQ.NanomolarconcentrationofNSC606985,acamptothecinanalog,inducesleukemic-cellapoptosisthroughproteinkinaseCdelta-dependentmechanisms.Blood.2005May1;105(9):3714-21.PMID:15671440
64)WangYY,ZhouGB,YinT,ChenB,ShiJY,LiangWX,JinXL,YouJH,YangG,ShenZX,ChenJ,XiongSM,ChenGQ,XuF,LiuYW,ChenZ,ChenSJ.AML1-ETOandC-KITmutation/overexpressionint(8;21)leukemia:implicationinstepwiseleukemogenesisandresponsetoGleevec.ProcNatlAcadSciUSA.2005Jan25;102(4):1104-9.PMID:15650049
65)YinT,WuYL,SunHP,SunGL,DuYZ,WangKK,ZhangJ,ChenGQ,ChenSJ,ChenZ.CombinedeffectsofAs4S4andimatinibonchronicmyeloidleukemiacellsandBCR-ABLoncoprotein.Blood.2004Dec15;104(13):4219-25.PMID:15339852
66)ZhaoKW,LiX,ZhaoQ,HuangY,LiD,PengZG,ShenWZ,ZhaoJ,ZhouQ,ChenZ,SimsPJ,WiedmerT,ChenGQ.ProteinkinaseCdeltamediatesretinoicacidandphorbolmyristateacetate-inducedphospholipidscramblase1geneexpression:itsroleinleukemiccelldifferentiation.Blood.2004Dec1;104(12):3731-8.PMID:15308560
67)ZhaoQ,TaoJ,ZhuQ,JiaPM,DouAX,LiX,ChengF,WaxmanS,ChenGQ,ChenSJ,LanotteM,ChenZ,TongJH.RapidinductionofcAMP/PKApathwayduringretinoicacid-inducedacutepromyelocyticleukemiacelldifferentiation.Leukemia.2004Feb;18(2):285-92.PMID:14628075
68)HuangY,DuKM,XueZH,YanH,LiD,LiuW,ChenZ,ZhaoQ,TongJH,ZhuYS,ChenGQ.Cobaltchlorideandlowoxygentensiontriggerdifferentiationofacutemyeloidleukemiccells:possiblemediationofhypoxia-induciblefactor-1alpha.Leukemia.2003Nov;17(11):2065-73.PMID:14523474
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