在岗研究生导师情况介绍
所系名称健康科学研究所
性别女
专业名称细胞生物学
技术职务研究员
行政职务无
Mail地址lyxu@sibs.ac.cn
指导博士
生总数2指导硕士
生总数7已毕业学生通讯地址上海重庆南路225号
目前博士
生数2目前硕士
生数4目前在校生邮政编码200025
研究方向autoimmunediseasesandimmuneregulation
研究工作autoimmunediseasesandimmuneregulation：multiplesclerosis;autoimmuneliverdiseases;liverregeneration;T-cellimmunity;
获奖情况
A.2007年上海医学会“上海医学科技奖”一等奖（第二完成人）
B.2008年上海市科委“上海科技进步奖”三等奖（第二完成人）
C.2008年上海交通大学晨星青年学者奖励计划
指导研究
生情况硕士研究生：6名；博士研究生：1名。
个人简介PhD(2000):KarolinskaInstitute,Sweden;
MedicalDegree(1995):ShandongMedicalUniversity,China
近期论文
1.FengD,WangY,MeiY,XuY,XuH,LuY,LuoQ,ZhouS,KongX,L-YXu.Stearoyl-CoAdesaturase1deficiencyprotectsmicefromimmune-mediatedliverinjury.LabInvest.2009.89(2):222-30.
2.WangY,LuoQQ,XuY,FengD,FeiJ,ChengQ,L-YXu.γ-AminobutyricAcidTransporter1NegativelyRegulatesTCellActivationandSurvivalthroughProteinKinaseC-DependentSignalingPathways.JournalofImmunology.2009;183(5):3488-95.
3.XuY,FengD,WangY,LuoQ,L-YXu.STAT3mediatesprotectionfromliverinflammationafterpartialhepatectomy.CellPhysiolBiochem.2009;2009.77(2):277-84.
4.LuoQ,WangY,FengD,XuY,L-YXu.Vasoactiveintestinalpeptideattenuatedimmune-mediatedliverinjuryviaacAMP-dependentpathway.EurJPharmacol.2009;607(1-3):226-33.
5.XuY,XueY,WangY,FengD,LinS,L-YXu.Multiple-modulationeffectsofOridoninonmicroglia:anti-inflammationandneuroprotection.IntImmunopharmacol.2009;9(3):360-5.
6.FengD,WangY,XuY,LuoQ,BinLan,L-YXu.Interleukin10deficiencyexacerbateshalothaneinducedliverinjurybyincreasinginterleukin8expressionandneutrophilinfiltration.BiochemPharmacol2008.77(2):277-84.
7.FengD,MeiY,WangY,ZhangB,WangC,L-YXu.TetrandrineprotectsmicefromconcanavalinA-inducedhepatitisthroughinhibitingNF-κBactivation.ImmunolLett.2008.121(2):127-33.
8.WangY,FengD,LiuG,LuoQ,XuY,LinS,FeiJ,L-YXu.γ-aminobutyricacidtransporter1negativelyregulatesTcellmediatedimmuneresponsesandamelioratesautoimmuneinflammationinthecentralnervoussystem.JImmunol.2008.181(12):8226-36.
9.WangY,MeiY,FendD,L-YXu.TriptolidemodulatesTcellinflammatoryresponsesandamelioratesexperimentalautoimmuneencephalomyelitis.JNeurosciRes.2008.86(11):2441-9.
10.FengD,L-YXu.LipidaccumulationinconcanavalinA-inducedhepatitis:Anothercauseforimpairedliverregenerationafterwards?Hepatology.2008.47(2):765.
11.XuY,FengD,WangY,LinS,L-YXu.TanshinoneIIASulfonateProtectsMiceFromConA-InducedHepatitisviaInhibitingNF-κBandIFN-γ/STAT1Pathways.JClinImmunol.2008.28:512-9.
12.LinS,WangY,XueY,FengD,XuY,L-YXu.TetrandrinesuppressesLPS-inducedastrocyteactivationviamodulatingIKKs-IκBα-NF-κBsignalingpathway.MolCellBiochem.2008.315:41-9.
13.XueY,WangY,FengD,XiaoBG,L-YXu.Tetrandrinesuppresseslipopolysaccharide-inducedmicroglialactivationbyinhibitingtheNF-κBpathway.ActaPharmacolSin.2008.29:245-51.
14.SunH,GongS,CarmodyRJ,HilliardA,LiL,SunJ,KongL,L-YXu,HilliardB,HuS,ShenH,YangX,ChenYH.TIPE2,anegativeregulatorofinnateandadaptiveimmunitythatmaintainsimmunehomeostasis.Cell.2008.133(3):415-26.
15.XiaoBG,MaCG,L-YXu,LinkH,LuCZ.IL-12/IFN-gamma/NOaxisplayscriticalroleindevelopmentofTh1-mediatedexperimentalautoimmuneencephalomyelitis.MolImmunol.2008.45(4):1191-6.
16.WangY,MeiYH,BaoS,L-YXu.Vasoactiveintesinalpolypeptideenhancesoraltolerancebyregulatingbothcellularandhumoralimmuneresponses.ClinExpImmunol.2007.148:178-87.
17.MeiYH,WangY,L-YXu.Suppressionofimmune-mediatedliverinjuryaftervaccinationwithattenuatedpathogeniccells.Immunollett.2007.110:29-35.
18.PengB,ZhaoY,XuL,L-YXu.ElectricpulsesappliedpriortointramuscularDNAvaccinationgreatlyimprovethevaccineimmunogenicity.Vaccine.2007.25(11):2064-73
19.罗清琼,王莹，徐凌云。他汀类药物对于免疫细胞的调节作用及机制免疫学杂志，2009.2:222-224.
20.王莹，徐凌云。Toll样受体在免疫调节中的枢纽作用-从多发性硬化研究中得到的启示.神经科学进展（五）2008.396-401.
21.薛旸，徐凌云。小胶质细胞与炎性介导的神经系统退行性病变。生命科学.2007.19(1):43-6.
22.林姝婷，徐凌云。EGCG的免疫调节作用及其机理的研究进展中国免疫学杂志.2007.23:954-7.
