马越鸣教授
职务：
药理学教研室主任、中药药理学实验室主任
研究领域：
中药药物代谢动力学和中药药效评价
邮箱：
mayueming_117@126.com

个人简介：
教育背景：
1978.2-1982.7皖南医学院临床医学(本科)
1984.9-1987.8皖南医学院药理学专业研究生(硕士)
工作经历、进修经历：
1982年8月至2000年6月在皖南医学院药理学教研室从事药理学教学和研究工作。2000年6月进入上海中医药大学中药学院，从事药理学/中药药理学教学与研究。主编和副主编《药理学》，作为编委参与编写《药理学》、《中药药理学》教材和多部学术专著。主持国家自然科学基金3项和教育部高校博士点基金、上海市科委、教委、卫生局等多项中药药理学研究项目，负责上海高校创新团队“复方中药药物代谢动力学与创新中药研究团队”的建设,发表学术论文100多篇。
目前负责的在研项目：
国家自然科学基金和教育部高校博士点基金。
所获荣誉、奖项：
上海中医药大学教学名师，优秀博士生导师
教学课程：
《药理学》、《基础药理学》、《中药药理学》、《药代动力学》、《药理学进展（西药）》、《中药药代动力学》等。
主要科研成果：
负责的项目“药物肠胃循环及药代动力学双峰理论的研究”获1997年安徽省自然科学三等奖、“泻心汤配伍规律和药效物质基础研究”获2007年上海市医学科技三等奖、“中医方剂药效物质基础分析方法的集成与应用”获2009年上海市科技进步二等奖和2010年中华医学科技二等奖。
主要社会兼职：中国药理学会药物代谢专业委员会委员、上海市药学会药理专业委员会委员、上海市药理学会药代动力学专业委员会委员。
科研领域：
中药药物代谢动力学，包括中药体内过程和动力学研究，主要进行基于药动学/药效学联合的中药药效物质基础和配伍规律研究、基于药动学的中药成药性评价研究等。
学术论文：

1.Ma BL, Yao MK, Zhong J, Ma YM*, Gao CL, Wu JS, Qiu FR, Wang CH, and Wang XH. Increased Systemic Exposure to Rhizoma Coptidis Alkaloids in Lipopolysaccharide-pretreated Rats due to Enhanced Intestinal Absorption. Drug Metab Dispos. 2012, 40(2): 381-388.
2.Shi R, Zhou H, Ma B, Ma Y*, Wang C, Wu D, Wang X, Luo H, Cheng N. Pharmacokinetics and Metabolism of Jatrorrhizine, a Gastric Prokinetic Drug Candidate. Biopharm Drug Dispos. 2012；33(3)：135-45
3.Bingliang Ma,Yueming Ma*. Pharmacokinetic properties, potential herb-drug interactions and acute toxicity of oral Rhizoma coptidis alkaloids. Expert Opin Drug Metab Toxicol. 2013，9(1): 51-61.
4.Tan Z, Zhu R, Shi R, Zhong J, Ma YM*, Wang C, Wang X, Cheng N. Involvement of rat organic cation transporter 2 in the renal uptake of jatrorrhizine. J Pharm Sci. 2013，102 (4):1333-1342.
5.Han XH, Zhong J, Guo JY, Shi R, Wang XH, Wang CH, Wang K, Du GL, Shen YH, Ma YM*. Relationships between pharmacokinetics and efficacy of Xiexin decoction in rats with experimental ulcerative colitis. Journal of Ethnopharmacology. 2013, 148( 1):182?189.
6.Wang Q, Shi R, Ma YM*, Jiang P, Zhong J, Cui HY, Liu P, Liu CH. Content determination of the major constituents of Yinchenzhufu decoction via ultra high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry. J Pharm Biomed Anal. 2013, 77C:88-93.
7.Zhou H, Shi R, Ma BL, Ma YM*, Wang C, Wu D, Wang X, Cheng N. CYP450 1A2 and multiple UGT1A isoforms are responsible for jatrorrhizine metabolism in human liver microsomes. Biopharm Drug Dispos. 2013 ;34(3):176-85.
8.Jiang P, Shi R, Wang Q, Ma YM*, Cui HY, Liu P, Liu CH. Simultaneous determination of eleven major components in Fugan Fang using high-performance liquid chromatography coupled with mass spectrometry. Biomed Chromatogr. 2013. 27(7): 874?881
9.Chen YR, Gao CL, Ma YM*, Qiu FR. Pharmacokinetic study of multiple active constituents after oral gavage of Guizhi decoction in rats using a LC?MS/MS method. Eur J Drug Metab Pharmacokinet. 2013; 38(4):283-293
10.Xie Y，Hu Y, Shen M, Ma Y*, Zhong J, Zhang N, Tao J，Wei L. Dissolution and Pharmacokinetic Properties of Alkaloids and Flavonoids in a Xiexin Multiple-unitDrug Delivery System. Drug Res 2013;63(10):501-509
11.Wu JS, Shi R, Zhong J, Lu X, Ma BL, Wang TM, Zan B, Ma YM*, Cheng NN, Qiu FR. Renal Protective Role of Xiexin Decoction with Multiple Active Ingredients Involves Inhibition of Inflammation through Downregulation of the Nuclear Factor-?B Pathway in Diabetic Rats. Evidence-Based Complementary and Alternative Medicine. Volume 2013, Article ID 715671, 15 pages
12.Jie Zhong, Wenxue Mao, Rong Shi, Peng Jiang, Qian Wang, Rong Zhu, Tianming Wang, Yueming Ma*. Pharmacokinetics of Liposomal-Encapsulated and Un-encapsulated Vincristine after Injection of Liposomal Vincristine Sulfate in Beagle Dogs. Cancer Chemotherapy and Pharmacology 2014; 73(3):459-66.
13.Tian-Ming Wang，Li-Qin Ding，Jia-Hua Jin, Rong Shi, Jie Zhong, Cui Gao, Qian Wang, Li Zhu and Yue-Ming Ma*. Simultaneous determination of 14 major components in Longhu Rendan pills by ultra-high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry. Anal. Methods, 2014; 6(9): 2923-2929
14.Tian-Ming Wang，Li-Qin Ding，Yi-Qun Jia，Jia-Hua Jin, Rong Shi, Li Zhu and Yue-Ming Ma*. Simultaneous determination of 14 major components in Longhu Rendan pills by ultra-high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry. Anal. Methods, 2014; 6(11): 3713?3719
15.Qian Wang, Peng Jiang, Fu-Yuan Ye, Rong Shi, Yue-Ming Ma*, Jie Zhong, Jia-Sheng Wu, Ping Liu, Cheng-Hai Liu, Yi-Qun Jia. Identification and pharmacokinetics of multiple constituents in rat plasma after oral administration of Yinchenzhufu decoction. Journal of Ethnopharmacology. 2014, 153( 3): 714?724