姓名： 贾薇 导师类别： 硕导

所在专业： 生物与医药（专业学位） 研究方向： 药用真菌化学
学院/单位： 上海市农业科学院
专业所属学院： 食品学院
专业技术职务： 研究员 行政职务： 高级
性别： 女 E-Mail： jiawei@saas.sh.cn
最高学位： 博士
通讯地址： 上海市奉贤区金齐路1000号食用菌所409室
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简历

贾薇，博士，研究员，上海海洋大学食品学院硕士生导师，上海市学位委员会专家。主要从事药用真菌活性物质的分离纯化、结构鉴定和生物活性研究，并对牛樟芝、灵芝、金针菇等的活性成分、药理作用，以及深层发酵技术等进行了深入的研究,利用亲和层析、ELISA 、CBA等技术首次在细胞和分子水平上发现了食用菌多糖在免疫细胞上的作用靶点和作用机制。2003-2004，作为访问****在德国柏林自由大学分子生物学与生物化学研究所从事食、药用菌组分的活性研究1年。主持和主要参与省部级项目近20项。主笔发表SCI收录文章14篇，国内一类期刊30多篇，主持获得保健食品证书1个。主要参与获得上海市科技进步三等奖1项、发明奖1项和发明专利5项,新品种2个。

教育经历


工作经历


研究成果


获奖情况


专利著作


论文发表

Zhendong Liu, Dongsheng Yu, Liang Li, Xiaoxiao Liu, Henan Zhang, Wenbo Sun, Chi-Chung Lin, Jiafu Chen, Zhi Chen, Wenhan Wang,* and Wei Jia,*. Three-Phase Partitioning for the extraction and purification of polysaccharides from the immunomodulatory medicinal mushroom Inonotus obliquus. Molecules 2019, 24, 403-417.
Hairui Yang, Xu Bai, Henan Zhang, Jingsong Zhang, Yingying Wu ,Chuanhong Tang, Yanfang Liu, Yan Yang, Zhendong Liu, Wei Jia,* and Wenhan Wang,* . Antrodin C, an NADPH Dependent Metabolism,Encourages Crosstalk between Autophagy and Apoptosis in Lung Carcinoma Cells by Use of an AMPK Inhibition-Independent Blockade of the Akt/mTOR Pathway. Molecules 2019, 24, 993-1018.
Hai- Rui Yang, Jin-Song Zhang, He-nan Zhang, Yan Yang, Yan-fang Liu, Wen-bo Sun, Wen-han Wang,* & Wei Jia*.Compound of Stout Camphor Medicinal Mushroom, Taiwanofungus camphoratus (Agaricomycetes), Induces Protective Autophagy in SPCA-1 Cells through AMPK Inhibition-Independent Blockade of the Akt/mTOR Pathway. International Journal of Medicinal Mushrooms, 2018, 20(8):727–738.
Wen-Han Wang, Li-Yuan Wang, Hai-Rui Yang, Ya-Ping Zhang, He-Nan Zhang, Hua Fan, Xiang-Li Zhao, Jing-Song Zhang,* & Wei Jia.* Antitumor Effect of By-1 from Spent Broth from Submerged Cultures of Stout Camphor Medicinal Mushroom, Taiwanofungus camphoratus (Higher Basidiomycetes), on A549 Adenocarcinoma Cells. International Journal of Medicinal Mushrooms, 2017, 19(3): 225–232.
Wei Jia, Yan-Yan Bai, Zhong Zhang, Na Feng, Jie Feng, Meng-Qiu Yan, Li-Na Zhu, Xin-Cheng Jia, Ming-Dao Wang, Jing-song Zhang,* & Hua Fan. Antitumor compounds from the stout camphor mushroom Taiwanofungus camphoratus (Higher Basidiomycetes) spent culture broth. International Journal of Medicinal Mushrooms, 2015, 17(6): 533–540.
Hua Liu, Wei Jia*, Jin-Song Zhang, Ying-Jie Pan. GC-MS and GC-olfactometry analysis of aroma compounds extracted from culture fluids of Antrodia camphorate. World Journal of Microbiology & Biotechnology, 2008, 24(8):1599-1602.
Wen-Han Wang, Jing-Song Zhang, Ting Feng, Jing Deng, Chi-Chung Lin, Hua Fan, Wen-Juan Yu, Hai-Ying Bao, Wei Jia*. Structural elucidation of a polysaccharide from Flammulina velutipes and its immunomodulation activities on mouse B lymphocytes. Scientific reports. 2018, 8:3120.
Wei Jia, # Jie Feng,# Jing-Song Zhang, Chi-Chung Lin, Wen-Han Wang, * Hong-Ge Chen*. Structural Characteristics of the Novel Polysaccharide FVPA1 from Winter Culinary-Medicinal Mushroom, Flammulina velutipes (Agaricomycetes), Capable of Enhancing Natural Killer Cell Activity against K562 Tumor Cells. International Journal of Medicinal Mushrooms, 2017, 19(6): 535–546.
Ting Feng#, Wei Jia,# Wen-Han Wang, Chi-Chung Lin, Hua Fan,Jing-Song Zhang,*& Hai-Ying Bao.* Structural Characterization and Immunological Activities of a Novel Water-Soluble Polysaccharide from the Fruiting Bodies of Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes). International Journal of Medicinal Mushrooms, 2016, 18(9): 807–819.
Jie Feng,# Na Feng, Yan Yang, Fang Liu, Jing-Song Zhang, * Wei Jia,* & Chi-Chung Lin. Simple and Reproducible Two-Stage Agitation Speed Control Strategy for Enhanced Triterpene Production by Lingzhi or Reishi Medicinal Mushrooms, Ganoderma lucidum ACCC G0119 (Higher Basidiomycetes) Based on Submerged Liquid Fermentation. International Journal of Medicinal Mushrooms, 2015, 17(12): 1151–1159.
Xinyu Liu, # Wei Jia, # Yi An, Kun Cheng, Mingdao Wang, Sen Yang, Hongge Chen*. Screening, gene cloning, and characterizations of an Acid-Stableα-Amylase. J. Microbiol. Biotechnol. 2015, 25(6), 828–836.
Jie Feng, Jing-Song Zhang*, Wei Jia*, Yan Yang, Fang Liu, and Chi-Chung Li. An unstructured kinetic model for the iImprovement of triterpenes production by Ganoderma lucidum G0119 based on nitrogen source effect. Biotechnology and Bioprocess Engineering. 2014, 19: 727-732.
Wei Jia, Jing-Song Zhang, Yun Jiang; Zhi-Yong Zheng; Xiao-Bei Zhan *; Chi-Chung Lin. Structure of oligosaccharide F21 derived from exopolysaccharide WL-26 produced by Sphingomonas sp. ATCC 31555. Carbohydrate Polymers. 2012, 90(1):60-66.
Wei Jia, Li Zhu, Jin-Song Zhang,*, Xiao-Bei Zhan,*, Yan-Yan Bai, Shuai Zhou, Yan-Fang Liu, Zhi-Yong Zheng, Chi-Chung Lin. Ultrasound-assisted degradation of a new bacterial exopolysaccharide WL-26 from Sphingomonas sp. African Journal of Biotechnology. 2012, 11(79): 14474-14481.