周平教授 复旦大学高分子科学系上海邯郸路220号邮编200433电话：021-55664038传真：02165640293E-mail:pingzhou@fudan.edu.cn
出生：1961，10，31

简历1979-1983：复旦大学物理二系放射化学专业，获理学学士学位。1983-1986：复旦大学物理二系物理化学专业，获理学硕士学位。1986-1993：复旦大学物理二系任教，从事激光化学研究。1993-1997：香港中文大学化学系物理化学专业，获理学博士学位，并做博士后工作。期间从事聚胺大环冠醚及其超分子化合物以及新型抗癌药物的合成。并用固体、液体核磁共振、激光光散射、分子设计以及量子化学方法研究化合物的结构及性质。 1998-2005，4：复旦大学高分子科学系副教授，从事丝素蛋白结构与功能的核磁共振研究；模拟丝素蛋白的合成及表征；组织工程用心脏瓣膜高分子支架材料的研究。2003,10-2004,4：苏黎世瑞士联邦高等理工学院，访问学者。在Meier, B.教授带领的固体核磁共振实验室从事丝素蛋白结构的研究。2005，4至今：复旦大学高分子科学系教授。
研究领域:1、 固体核磁共振波谱学在高分子及生物大分子领域的应用2、 蛋白质、高分子之结构、运动与功能关系研究3、 用于组织工程的生物医用材料研究教学经验：1、 高分子研究方法——NMR在高分子研究中的应用2、 高分子化学实验3、 物理化学实验4、 分析化学实验
主持主要研究课题：1、用DFT和固体NMR研究丝蛋白体系中氢键、构象与功能的关系 （国家自然科学基金，已完成）2、丝心蛋白构象转变动力学及机理的研究（国家教委青年骨干教师资助计划，已完成）3、组织工程技术构建自体活心脏瓣膜（复旦大学Med-X基金，已完成）4、深入研究丝蛋白构象及成丝机理以及类丝素纤维的合成（国家自然科学基金，在研项目）5、类丝素高分子聚合物结构、构像、加工工艺与其功能关系的固体核磁共振（国家自然科学基金，在研项目）
近年来发表期刊论文：[1] Ping Zhou, Steve C. F. Au-Yeung and Xiaoping Xu, (1999) A DFT and 59Co Solid State NMR Study of the Second Sphere Interaction in Polyammonium Macrocycles Cobalt Cyanide Supercomplexes, J. Am. Chem. Soc. 121(5), 1030-1036.[2] Ping Zhou, Feng Xue, Steve. C. F. Au-Yeung and Xiaoping Xu, (1999) Crystal Structures of [18]aneH2K[Co(CN)6]4H2O, [16]aneN4H2K[Co(CN)6] and [12]aneN4H3[Co(CN)6]2H2O. Insight into the Electrostatic and Hydrogen Bonding Interaction in Self-Assembling Supercomplexes, Acta Cryst. B, 55, 389-395.[3] Zhengzhong Shao, Yuyu Sun, Ping Zhou, and Tongyin Yu, (1999) Specific Interaction in Silk Fibroin-Poly(Potassium acrylate) Blends, Polymer J. 31, 470-475.[4] Ping Zhou, Steve C. F. Au-Yeung and Qing’an Meng, (1999) The Second Sphere Interaction in the Supramolecular Complexes Studied by 59Co Solid Static NMR, Acta Physico-Chimica Sinica 15(6), 533-540.[5] Heng Lin, Zheng-zhong Shao, Ping Zhou, Qinwei Gao, Tongyin Yu, (2000) Synthesis and Conformation of Poly(L-?-Chloroethyl glutamate), Chem. J. Chinese Univ. 21(5), 819-821.[6] Xin Chen, Zhengzhong Shao, Yufang Huang, Yao Huang, Ping Zhou, Tongyin Yu, (2000) Influence of Crosslinking Agent content on Structure and Properties of Glutaraldehyde Crosslinked Chitosan Membranes, Acta Chimica Sinica 58(12), 1654-1659.[7] Qinwei Gao, Zhengzhong Shao, Yuyu Sun, Heng Lin, Ping Zhou, Tongyin Yu, (2000) Complex formation of silk fibroin with poly(acrylic acid)，Polymer J. 32(3), 269-274.[8] Xin Chen, Zhengzhong Shao, Nebojsa S. Marinkovic, Lisa M. Miller, Ping Zhou, Mark R. Chance, (2001) Conformation transition kinetics of regenerated Bombyx mori silk fibroin membrane monitored by time-resolved FTIR spectroscopy，Biophys. Chem. 89(1), 25-34.[9] Guiyang Li, Ping Zhou, Yaojun Sun, Wenhua Yao, Yong Mi, Huiyig Yao, Zhengzhong Shao and Tongyin Yu, (2001) The Effect of Metal Ions on the Conformation Transition of Silk Fibroin, Chem. J. Chinese Univ. 22(5), 860-862.[10] Yong Yang, Xin Chen, Ping Zhou, Wenhua Yao, Zhengzhong Shao, (2001) Mechanical Properties of Bombyx mori Silk at Different Temperatures, Chem. J. Chinese Univ. 22(9), 1592-1596.[11] Ping Zhou, Guiyang Li, Zhengzhong Shao, Xiaoyun Pan, Tongyin Yu, (2001) Structure of Bombyx Mori Silk Fibroin Based on the DFT Chemical Shift Calculation, J. Phys. Chem. B 105(50), 12469-12476.[12] Guiyang Li, Ping Zhou, Zhengzhong Shao, Xun Xie, Xin Chen, Honghai Wang, Lijuan Chunyu, Tongyin Yu, (2001) Natural Silk Spinning Process: A nucleation-Dependent Aggregation Mechanism? Eur. J. Biochem. 268(24), 6600-6606.[13] Wang, P.; Liu, R.; Wu, X.; Ma, H.; Cao, X.; Zhou, P.; Zhang, J.; Weng, X.; Zhang, X.-L.; Qi, J.; Zhou, X.; Weng, L. (2003); A Potent, Water-Soluble and Photoinducible DNA Cross-Linking Agent, J. Am. Chem. Soc.; (Communication); 125(5), 1116-1117.[14] XIE Xun , ZHOU Ping , YAO Jin-Rong , ZOU Peng , SHAO Zheng-Zhong, (2003) Synthesis of 1 ,6-Diaminohexane Mono-end-protected by t-butyloxycarbonyl, Chinese Journal of Synthetic Chemistry, 11（5），406-408,.[15] Ping Zhou, Steve C. F. Au-Yeung, (2003) Determination of rotational reorientation correlation time and 59Co nuclear quadrupolar coupling constant of polyammonium macrocyclic cobalticyanide supercomplexes in dilute aqueous solutions – an application of dynamic laser light scattering method，Chinese J. Nuclear Magnetic. Resonance. (2003)，20（4），319－328[16] Zhou L, Chen X, Shao ZZ, Zhou P, Knight DP, Vollrath F，（2003）Copper in the silk formation process of Bombyx mori silkworm，FEBS LETTERS， 554 (3)， 337-341.[17] Yao, JR; Chen, X; Zhou, P; Shao, ZZ; Yu, TY, (2003) Vibrational spectroscopy studies on the blend films of silk fibroin and silk-protein like polymers， CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE，24 (11)， 2113-2115.[18] Liu JH, Chen X, Shao ZZ, Zhou P，（2003）Preparation and characterization of chitosan/Cu(II) affinity membrane for urea adsorption，J. APPL. POLYM. SCI. 90 (4): 1108-1112[19] Yao JR, Xiao DH, Chen X, Zhou P, Yu TY, Shao ZZ, (2003) Synthesis and solid-state secondary structure investigation of silk-proteinlike multiblock polymers, Macromolecules, 36 (20), 7508-7512[20] Chen X, Zhou L, Shao ZZ, Zhou P, Knight DP, Vollrath F，(2003)Conformation transition of silk protein membranes monitored by time-resolved FT-IR spectroscopy - Conformation transition behavior of regenerated silk fibroin membranes in alcohol solution at high concentrations，ACTA CHIMICA SINICA 61 (4): 625-629.[21] YU Tong-yin , MEI Na , CHEN Guang , ZHOU Ping, SHAO Zheng-zhong , CHEN Xin , YAO Jin-rong (2003), Application of Silk Fibroin in Tissue Engineering, Journal of Fudan University (Natural Science), 42 (6), 828-832.[22] ZHOU Ping, Steve C.F.Au-Yeung, (2004) HYDROGEN BONDING INTERACTION IN COBALTIC SUPRAMOLECULAR COMPLEXES—STUDIED 59Co NMR AND MOLECULAR MODELLING, Chinese Journal of Magnetic Resonance, 21 (1), 1-15.[23] Guang Chen, Ping Zhou, Luanfeng Pan, Na Mei, Chungen Wu, Xin Chen, Zhengzhong Shao(2004) Silk fibroin modified porous poly(ε-caprolactone) scaffold for human fibroblast culture in vitro，Journal of Materials Science: Materials in Medicine，15 (6): 671-677。[24] Xie, X; Zhou, P; Deng, F; Wu, PY; Zong, XH; Yao, WH, (2004) Influence of pH value on the conformation transition of silk fibroin, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 25 (5): 961-965 MAY 2004[25] Chen, X; Huang, YF; Shao, ZZ; Huang, Y; Zhou, P; Knight, DP; Vollrath, F. Function of potassium in spinning process of spider Nephila, （2004）CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 25 (6): 1160-1163。 [26] Chen G, Zhou P, Pan LF, Mei N, Wu CG, Chen X, Shao ZZ, (2004) Growth of human fetal lung fibroblasts on the natural biomaterial-chitosan scaffold, ACTA CHIMICA SINICA 62 (10): 992-997.[27] Yang YH, Shao ZZ, Chen X, Zhou P (2004) Optical spectroscopy to investigate the structure of regenerated Bombyx mori silk fibroin in solution, BIOMACROMOLECULES 5 (3): 773-779.[28] Ping Zhou, Xun Xie, David P. Knight, Xiao-Hong Zong, Feng Deng, Wen-Hua Yao, (2004), Effects of pH and Calcium ions on the Conformation Transitions in Silk Fibroin Using 2D Raman Correlation Spectroscopy and 13C Solid State NMR, Biochemistry-US, 43（35）, 11302-11311.[29] Xiaohong Zong, Ping Zhou, Zhengzhong Shao, Shiming Chen, Xin Chen, Bingwen Hu, Feng Deng, Wenhua Yao (2004), Effect of pH and Cu(II) on the Conformation Transitions of Silk Fibroin Based on EPR, NMR and Raman Spectroscopy, Biochemistry-US, 43（38）, 11932-11941.[30] Yi Liu, Zhengzhong Shao, Ping Zhou, Xin Chen (2004), Thermal and crystalline behaviour of silk fibroin/nylon 66 blend films, Polymer, 45（22）, 7705-7710.[31] Yang Y, Chen X, Shao ZZ, Zhou P, Porter D, Knight DP, Vollrath F (2005), Toughness of spider silk at high and low temperatures, Advanced Materials 17 (1): 84-88 JAN 18 2005.[32] Na Mei, Guang Chen, Ping Zhou, Luan-Feng Pan, Chun-Gen Wu, Xin Chen, Zheng-Zhong Shao (2005), Biocompatibility of Poly( -caprolactone) Scaffold Modified by Chitosan—The Fibroblasts Proliferation in vitro, J. Biomater. Appl. 19（4）323-339.[33] ZONG Xiaohong, ZHOU Ping, SHAO Zhengzhong, WANG Honghai & CHUNYU Lijuan (2005), Cu(II) effect on the conformation of regenerated silk fibroin in dilute aqueous solution, Chinese Science Bulletin, 50 (11), 1080-1084.近年来发表主要会议论文：[1] ZHOU, Ping， DFT and solid state NMR studies of the conformation, interaction and function for Bombyx mori, 6th Pacific Polymer Conference, 1999, Guangzhou, China, p9-2B-14.[2] 周平，蚕丝蛋白体系中构象与氢键的DFT和固体NMR研究，1999高分子学术论文报告会论文集，1999，上海，p-e18.[3] 周平，蚕丝蛋白结构及其化学位移，第十一届全国波谱学学术会议论文摘要集，2000，南京，p38.[4] 周平，丝素蛋白构象转变的金属离子效应，2001年全国高分子学术论文报告会，2001，郑州，p-h24.[5] 周平，Cu(II)-丝素蛋白络合物配位结构的EPR研究，第十二届全国波谱学学术会议论文摘要集，2002，大连，p46.[6] 周平，用于组织工程支架材料PHA的生物相容性的改性研究，2003年全国高分子学术论文报告会, 2003，杭州，p-E21.[7] ZHOU, Ping，Fabrication of Porous PCL-SF Scaffold and Characterization for Tissue Engineering, Preprints of Third East Asia Polymer Conference, 2004, Chengdu, China, p306.[8] 周平，蜘蛛牵引丝形态的13C NMR研究，第十三届全国波谱学学术会议论文摘要集, 2004, 乌鲁木齐，p26.

诚挚欢迎对生物大分子结构、功能及其应用研究感兴趣的本科生及研究生参加本课题组的工作。

CURRICULUM VITAE
Ping ZHOU
Born:
Oct. 31, 1961
Born place:
P. R. China
Address:
Dept. of Macromolecular Science
Fudan University
Shanghai 200433, P. R. China
Tel: 86-21-55664038, Fax: 86-21-65640293
Email: pingzhou@fudan.edu.cn

Education:
Fudan University, China, B.S., 1983, Radiochemistry.
Fudan University, M.S., 1986, Physical chemistry.
The Chinese University of Hong Kong, Ph.D., 1997, Physical chemistry

Academic Appointments:
l Professor, Department of Macromolecular Science, Fudan University
(Apr. 2005-now)
l Associate Prof., Department of Macromolecular Science, Fudan University
(May, 1999-Apr. 2005).
l Lecturer, Department of Physics II, Fudan University
(Sep., 1988-May, 1999).
l Assistant, Department of Physics II, Fudan University
(June, 1986-Sep., 1988).
l Postdoctoral fellow, Department of Chemistry, The Chinese University
of Hong Kong (July, 1997-Dec. 1997).
l Visiting Scholar, Department of Zoology, Oxford University, UK
(July-Aug. 2002).
l Visiting Scholar, Lab of Physical Chemistry, ETH Zurich, Switzerland.
(Oct. 2003-Apr. 2004)

Other Appointments and Memberships
Member of Chinese Chemistry Society.
Member of Chinese Physics Society.

Research Interests
Biomolecular and polymer NMR Spectroscopy
Physics, Structure and function of biomolecules and polymers
Tissue Engineering.

Recent Research Publications:
[1] Ping Zhou, Steve C. F. Au-Yeung and Xiaoping Xu, (1999) A DFT and 59Co Solid State NMR Study of the Second Sphere Interaction in Polyammonium Macrocycles Cobalt Cyanide Supercomplexes, J. Am. Chem. Soc. 121(5), 1030-1036.
[2] Ping Zhou, Feng Xue, Steve. C. F. Au-Yeung and Xiaoping Xu, (1999) Crystal Structures of [18]aneH2K[Co(CN)6]4H2O, [16]aneN4H2K[Co(CN)6] and [12]aneN4H3[Co(CN)6]2H2O. Insight into the Electrostatic and Hydrogen Bonding Interaction in Self-Assembling Supercomplexes, Acta Cryst. B, 55, 389-395.
[3] Zhengzhong Shao, Yuyu Sun, Ping Zhou, and Tongyin Yu, (1999) Specific Interaction in Silk Fibroin-Poly(Potassium acrylate) Blends, Polymer J. 31, 470-475.
[4] Ping Zhou, Steve C. F. Au-Yeung and Qing’an Meng, (1999) The Second Sphere Interaction in the Supramolecular Complexes Studied by 59Co Solid Static NMR, Acta Physico-Chimica Sinica 15(6), 533-540.
[5] Heng Lin, Zheng-zhong Shao, Ping Zhou, Qinwei Gao, Tongyin Yu, (2000) Synthesis and Conformation of Poly(L-?-Chloroethyl glutamate), Chem. J. Chinese Univ. 21(5), 819-821.
[6] Xin Chen, Zhengzhong Shao, Yufang Huang, Yao Huang, Ping Zhou, Tongyin Yu, (2000) Influence of Crosslinking Agent content on Structure and Properties of Glutaraldehyde Crosslinked Chitosan Membranes, Acta Chimica Sinica 58(12), 1654-1659.
[7] Qinwei Gao, Zhengzhong Shao, Yuyu Sun, Heng Lin, Ping Zhou, Tongyin Yu, (2000) Complex formation of silk fibroin with poly(acrylic acid)，Polymer J. 32(3), 269-274.
[8] Xin Chen, Zhengzhong Shao, Nebojsa S. Marinkovic, Lisa M. Miller, Ping Zhou, Mark R. Chance, (2001) Conformation transition kinetics of regenerated Bombyx mori silk fibroin membrane monitored by time-resolved FTIR spectroscopy，Biophys. Chem. 89(1), 25-34.
[9] Guiyang Li, Ping Zhou, Yaojun Sun, Wenhua Yao, Yong Mi, Huiyig Yao, Zhengzhong Shao and Tongyin Yu, (2001) The Effect of Metal Ions on the Conformation Transition of Silk Fibroin, Chem. J. Chinese Univ. 22(5), 860-862.
[10] Yong Yang, Xin Chen, Ping Zhou, Wenhua Yao, Zhengzhong Shao, (2001) Mechanical Properties of Bombyx mori Silk at Different Temperatures, Chem. J. Chinese Univ. 22(9), 1592-1596.
[11] Ping Zhou, Guiyang Li, Zhengzhong Shao, Xiaoyun Pan, Tongyin Yu, (2001) Structure of Bombyx Mori Silk Fibroin Based on the DFT Chemical Shift Calculation, J. Phys. Chem. B 105(50), 12469-12476.
[12] Guiyang Li, Ping Zhou, Zhengzhong Shao, Xun Xie, Xin Chen, Honghai Wang, Lijuan Chunyu, Tongyin Yu, (2001) Natural Silk Spinning Process: A nucleation-Dependent Aggregation Mechanism? Eur. J. Biochem. 268(24), 6600-6606.
[13] Wang, P.; Liu, R.; Wu, X.; Ma, H.; Cao, X.; Zhou, P.; Zhang, J.; Weng, X.; Zhang, X.-L.; Qi, J.; Zhou, X.; Weng, L. (2003); A Potent, Water-Soluble and Photoinducible DNA Cross-Linking Agent, J. Am. Chem. Soc.; (Communication); 125(5), 1116-1117.
[14] XIE Xun , ZHOU Ping , YAO Jin-Rong , ZOU Peng , SHAO Zheng-Zhong, (2003) Synthesis of 1 ,6-Diaminohexane Mono-end-protected by t-butyloxycarbonyl, Chinese Journal of Synthetic Chemistry, 11（5），406-408,.
[15] Ping Zhou, Steve C. F. Au-Yeung, (2003) Determination of rotational reorientation correlation time and 59Co nuclear quadrupolar coupling constant of polyammonium macrocyclic cobalticyanide supercomplexes in dilute aqueous solutions – an application of dynamic laser light scattering method，Chinese J. Nuclear Magnetic. Resonance. (2003)，20（4），319－328
[16] Zhou L, Chen X, Shao ZZ, Zhou P, Knight DP, Vollrath F，（2003）Copper in the silk formation process of Bombyx mori silkworm，FEBS LETTERS， 554 (3)， 337-341.
[17] Yao, JR; Chen, X; Zhou, P; Shao, ZZ; Yu, TY, (2003) Vibrational spectroscopy studies on the blend films of silk fibroin and silk-protein like polymers， CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE，24 (11)， 2113-2115.
[18] Liu JH, Chen X, Shao ZZ, Zhou P，（2003）Preparation and characterization of chitosan/Cu(II) affinity membrane for urea adsorption，J. APPL. POLYM. SCI. 90 (4): 1108-1112
[19] Yao JR, Xiao DH, Chen X, Zhou P, Yu TY, Shao ZZ, (2003) Synthesis and solid-state secondary structure investigation of silk-proteinlike multiblock polymers, Macromolecules, 36 (20), 7508-7512
[20] Chen X, Zhou L, Shao ZZ, Zhou P, Knight DP, Vollrath F，(2003)Conformation transition of silk protein membranes monitored by time-resolved FT-IR spectroscopy - Conformation transition behavior of regenerated silk fibroin membranes in alcohol solution at high concentrations，ACTA CHIMICA SINICA 61 (4): 625-629.
[21] YU Tong-yin , MEI Na , CHEN Guang , ZHOU Ping, SHAO Zheng-zhong , CHEN Xin , YAO Jin-rong (2003), Application of Silk Fibroin in Tissue Engineering, Journal of Fudan University (Natural Science), 42 (6), 828-832.
[22] ZHOU Ping, Steve C.F.Au-Yeung, (2004) HYDROGEN BONDING INTERACTION IN COBALTIC SUPRAMOLECULAR COMPLEXES—STUDIED 59Co NMR AND MOLECULAR MODELLING, Chinese Journal of Magnetic Resonance, 21 (1), 1-15.
[23] Guang Chen, Ping Zhou, Luanfeng Pan, Na Mei, Chungen Wu, Xin Chen, Zhengzhong Shao(2004) Silk fibroin modified porous poly(ε-caprolactone) scaffold for human fibroblast culture in vitro，Journal of Materials Science: Materials in Medicine，15 (6): 671-677。
[24] Xie, X; Zhou, P; Deng, F; Wu, PY; Zong, XH; Yao, WH, (2004) Influence of pH value on the conformation transition of silk fibroin, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 25 (5): 961-965 MAY 2004
[25] Chen, X; Huang, YF; Shao, ZZ; Huang, Y; Zhou, P; Knight, DP; Vollrath, F. Function of potassium in spinning process of spider Nephila, （2004）CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 25 (6): 1160-1163。
[26] Chen G, Zhou P, Pan LF, Mei N, Wu CG, Chen X, Shao ZZ, (2004) Growth of human fetal lung fibroblasts on the natural biomaterial-chitosan scaffold, ACTA CHIMICA SINICA 62 (10): 992-997.
[27] Yang YH, Shao ZZ, Chen X, Zhou P (2004) Optical spectroscopy to investigate the structure of regenerated Bombyx mori silk fibroin in solution, BIOMACROMOLECULES 5 (3): 773-779.
[28] Ping Zhou, Xun Xie, David P. Knight, Xiao-Hong Zong, Feng Deng, Wen-Hua Yao, (2004), Effects of pH and Calcium ions on the Conformation Transitions in Silk Fibroin Using 2D Raman Correlation Spectroscopy and 13C Solid State NMR, Biochemistry-US, 43（35）, 11302-11311.
[29] Xiaohong Zong, Ping Zhou, Zhengzhong Shao, Shiming Chen, Xin Chen, Bingwen Hu, Feng Deng, Wenhua Yao (2004), Effect of pH and Cu(II) on the Conformation Transitions of Silk Fibroin Based on EPR, NMR and Raman Spectroscopy, Biochemistry-US, 43（38）, 11932-11941.
[30] Yi Liu, Zhengzhong Shao, Ping Zhou, Xin Chen (2004), Thermal and crystalline behaviour of silk fibroin/nylon 66 blend films, Polymer, 45（22）, 7705-7710.
[31] Yang Y, Chen X, Shao ZZ, Zhou P, Porter D, Knight DP, Vollrath F (2005), Toughness of spider silk at high and low temperatures, Advanced Materials 17 (1): 84-88 JAN 18 2005.
[32] Na Mei, Guang Chen, Ping Zhou, Luan-Feng Pan, Chun-Gen Wu, Xin Chen, Zheng-Zhong Shao (2005), Biocompatibility of Poly( -caprolactone) Scaffold Modified by Chitosan—The Fibroblasts Proliferation in vitro, J. Biomater. Appl. 19（4）323-339.
[33] ZONG Xiaohong, ZHOU Ping, SHAO Zhengzhong, WANG Honghai & CHUNYU Lijuan (2005), Cu(II) effect on the conformation of regenerated silk fibroin in dilute aqueous solution, Chinese Science Bulletin, 50 (11), 1080-1084.

Cordially welcome the undergraduate and graduate students who are interested in the researches of structures, functions and their applications of biomacromolecules to join our group.