研究方向
1. 作用靶标特异的仿生农药化学：昆虫生长调节剂(苯甲酰脲类几丁质抑制剂、具有蜕皮激素活性的非甾醇类二芳酰肼类化合物)；含恶二唑哒嗪酮类化合物拒食剂；鱼尼丁受体氟虫双酰胺、氯虫苯甲酰胺类化合物。
2. 高效有机合成方法学(新型多组分反应的设计；多组分反应在农药、医药中的应用；点击化学参与的多组分反应)。
3. 新型含氟砌块的多组分反应；含氟活性化合物的合成。碳氟键的活化及在环境保护中的应用。

Novel synthesis of difluoromethyl-containing 1,4-disubstituted 1,2,3-triazoles via a click-multicomponent reaction and desulfanylation strategy
Jian Zhang, Jingjing Wu, Li Shen, Guanyi Jin, and Song Cao*
Adv Synth Catal, 2011, 353, 580-584

One-pot synthesis of difluoromethyl-containing dihydropyrimidinones catalyzed by Yb(PFO)3 under solvent and dehydrating agent free conditions
Mingxi Wu, Jinlong Yu, Wenwen Zhao, Jingjing Wu, Song Cao*
J Fluorine Chem, 2011, 132, 155-159

Non-catalytic conversion of C-F bonds of gem-difluoromethylene derivatives to C-H bonds with lithium aluminum hydride under room temperature
JingJing Wu, JianHang Cheng, Jian Zhang, Li Shen, XuHong Qian and Song Cao*
Tetrahedron, 2011, 67, 285-288

K2CO3-assisted one-pot sequential synthesis of 2-trifluoromethyl-6-difluoromethylpyridine-3,5-dicarboxylates under solvent-free conditions
Li Shen, Song Cao*, Jingjing Wu, Hui Li, Jian Zhang, Mingxi Wu, Xuhong Qian*
Tetrahedron Letters, 2010, 51, 4866-4869