刘媛媛
化学与分子工程学院??????


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个人资料
部门： 化学与分子工程学院
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电子邮箱： yyliu@chem.ecnu.edu.cn
办公地址： 闵行校区理工学院化学系417
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2015.3-2017.9 化学与分子工程学院 科研秘书
科研经历：
2017.12至今 华东师范大学，副教授
2014-2017 华东师范大学，讲师，晨晖****
2015.9-11 北京大学余志祥教授课题组，短期访学
2009-2014 上海交通大学，博士（导师：张万斌 教授）
2012-2013 日本东北大学，亚洲校园计划（导师：Prof. Ilya Gridnev, Prof. Masahiro Terada）
2012. 1-3 日本东京大学，Global COE项目（导师：Prof. Makoto Fujita）
2005-2009 上海交通大学，本科
科研项目：
国家自然科学基金-面上项目（**，2019.01.01-2022.12.31）主持
国家自然科学基金-青年科学基金项目（**，2016.01.01-2018.12.31）主持
上海市2016年度“晨光计划”项目（16CG22，2017.1-2018.12) 主持
荣誉奖励：
2017主讲课程《有机化学及实验（生物菁英班）》，获得“2017年度华东师范大学在线教平台优质课程建设项目”
的资助支持。
2016 上海市研究生优秀成果（学位论文）
2014 上海市普通高等学校优秀毕业生


研究方向
有机合成方法学
不对称催化反应设计及应用
理论计算化学及NMR对有机反应机理的探索研究




开授课程


科研项目


学术成果
发表论文：

[19]Shan Xu, Zhan-Ming Zhang, Bing Xu, Bing Liu, Yuanyuan Liu,* and Junliang Zhang*, “Enantioselective Regiodivergent Synthesis of Chiral Pyrrolidines withTwo Quaternary Stereocenters via Ligand-Controlled Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloadditions”,J. Am. Chem. Soc. 2018, 140, 2272?2283.


[18]Shenhuan Li,? Yuanyuan Liu,? Ben Huang, Tao Zhou, Hongmei Tao, Yuanjing Xiao, Lu Liu,* and Junliang Zhang*, “Phosphine-Catalyzed Asymmetric Intermolecular Cross-Vinylogous Rauhut?Currier Reactions of Vinyl Ketones with para-Quinone Methides”, ACS Catal. 2017, 7, 2805?2809.

[17]Bing Liu, Zhan-Ming Zhang, Bing Xu, Shan Xu, Hai-Hong Wu, Yuanyuan Liu* and Junliang Zhang*, “Cu(I)-Catalyzed Michael Addition of Ketiminoesters to β-Trifluoromethyl, β,β-Disubstituted Enones: A Rapid Access to 1-Pyrrolines Bearing a Quaternary All-Cabon Stereocenter”, Org. Chem. Front., 2017, 4, 1772–1776.
[16]Yuanyuan Liu, Wenbo Li and Junliang Zhang*, “Chiral ligands designed in China”, Natl. Sci. Rev.2017, 4, 326-358.
[15]Yanzhao Wang, Yuanyuan Liu, Kun Li, Guoqiang Yang*, and Wanbin Zhang* Adv. Synth. Catal. 2017, 359, 1933-1941.
[14] Liu, Yuanyuan* and Zhang, Wanbin* “Development of Cu-Catalyzed Asymmetric Addition of Boron toOlefin”,Chin. J. Org. Chem. 2016, 36, 2249-2271.

[13] Xingcan Cheng, Yuanyuan Zhou, Fangfang Zhang, Kai Zhu, Yuanyuan Liu, and Yanzhong Li*, “Base-PromotedTandem Reaction Involving Insertion into Carbon–Carbon σ-Bonds: Synthesis of Xanthone and ChromoneDerivatives”, Chem. Eur. J. 2016, 22, 12655–12659.
[12] Fangfang Zhang, Zhengchen Qin, Lingkai Kong, Yulei Zhao, Yuanyuan Liu, and Yanzhong Li*, “Metal/BenzoylPeroxide (BPO)-Controlled Chemoselective Cycloisomerization of (o?Alkynyl)phenyl Enaminones: Synthesis of α?Naphthylamines and Indeno[1,2?c]pyrrolones”, Org. Lett. 2016, 18, 5150?5153.
[11] Lingkai Kong, Yushang Shao, Yanli Li, Yuanyuan Liu,* and Yanzhong Li*, “LDA-Promoted Synthesis of3?Amino Furans by Selective Lithiation of Enaminones”, J. Org. Chem. 2015, 80, 12641?12645.
[10] Lingkai Kong, Yuanyuan Zhou, He Huang, Yang Yang, Yuanyuan Liu,* and Yanzhong Li*, “Copper-Catalyzed Synthesis of Substituted Quinolines via C?N Coupling/Condensation from ortho-Acylanilines and Alkenyl Iodides”, J. Org. Chem. 2015, 80, 1275?1278.
[9] Yulei Zhao, Fangfang Zhang, Wenjun Yao, Chengyu Wang, Yuanyuan Liu,* Yanzhong Li*, “Base-PromotedApproach to Highly Functionalized Conjugated Dienes through Enamine Migration”, Eur. J. Org. Chem. 2015,7984–7991.
[8] Yuanyuan Liu, Ilya D. Gridnev,* and Wanbin Zhang*, “Mechanism of Asymmetric Hydrogenation of Exocyclicα,β-Unsaturated Carbonyl Compounds with Ir/BiphPHOX Catalyst: NMR and DFT Study”, Angew. Chem. Int. Ed. 2014, 53, 1901-1905.
[7] Ilya D. Gridnev,* Yuanyuan Liu, and Tsuneo Imamoto*, “Mechanism of Asymmetric Hydrogenation of β- Dehydroamino Acids Catalyzed by Rhodium Complexes. Large-Scale Experimental and Computational Study”, ACS Catal., 2014, 4, 203-219.

[6] Ilya D. Gridnev,* Christina Kohrt, andYuanyuan Liu, “Direct Experimental and Computational Evidence for the Dihydride Pathway in TangPHOS-Rh Catalysed Asymmetric Hydrogenation”,Dalton Trans.2014,43, 1785-1790.

[5] Yuanyuan Liu, Wanbin Zhang*, “Iridium-Catalyzed Asymmetric Hydrogenation ofa-Alkylidene Succinimides”,Angew. Chem. Int. Ed.2013,52, 2203-2206;highlighted by Mark Lautens and Harald Weinstabl inSYNFACTS2013,9, 0506;《有机化学》亮点介绍：Chin. J. Org. Chem.2013,33, 868.
[4] Kun Li, Guoqiang Yang,??Yuanyuan Liu??, Wanbin Zhang*, “Chiral Polymetallic Catalysts and their Application in Asymmetric Catalysis”,Chin. J. Org. Chem.2013,33, 749-759. (review)

[3] Yuanyuan Liu, Dongmei Yao, Kun Li, Fengtao Tian, Fang Xie, Wanbin Zhang*, “Iridium-Catalyzed Asymmetric Hydrogenation of 3-Substituted Unsaturated Oxindoles to Prepare Chiral C3-Mono Substituted Oxindoles”, Tetrahedron2011, 67, 8445-8450.
[2] Yuanyuan Liu, Guoqiang Yang, Dongmei Yao, Fengtao Tian, Wanbin Zhang*, “Convenient Synthesis ofTropos Phosphine-Oxazoline Ligands”,Sci. China Chem.2011, 54, 87-94.（邀稿）
[1] Fengtao Tian, Dongmei Yao, Yuanyuan Liu, Fang Xie, Wanbin Zhang*, “Iridium-Catalyzed Highly Enantioselective Hydrogenation of Exocyclic α,β-Unsaturated Carbonyl Compounds”, Adv. Synth. Catal.2010, 352, 1841-1845; highlighted by Hisashi Yamamoto in SYNFACTS2011, 1, 0064.

授权专利：
[1] 专利名称：轴不安定联苯类膦-噁唑啉手性配体的合成方法；专利号：ZL2010 1 **.2
[2] 专利名称：用铱手性催化剂不对称氢化3-亚烯基取代吲哚酮的方法；专利号：ZL 2011 1 **.6
[3] 专利名称：C-3位取代的手性琥珀酰亚胺及其制备方法；中国发明专利申请号: 9.2


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