吴琦,男,1973年出生,博士导师
工作单位 生命科学学院
行政职务 生物化学与分子生物学系主任，生物化学与分子生物学学科负责人。
单位电话
电子邮箱 wuqi@sicau.edu.cn
招生专业 【博士】:071010生物化学与分子生物学,【学硕】:071010生物化学与分子生物学，【专硕】:086000生物与医药
◆个人简历
吴琦，博士，教授，博士生导师，生物化学与分子生物学系主任，四川省生物化学与分子生物学学会理事。先后主持主研国家级和省级科研课题十余项，参与获得省级科技进步奖一等奖2项，三等奖1项，发表论文50余篇，其中SCI收录20余篇。现主要从事植物次生代谢调控及抗逆分子机制研究，在苦荞黄酮合成代谢酶学机理研究及转录因子分子调控、苦荞抗逆相关转录因子调控机制研究在领域内处于领先水平。
◆工作经历
2012年至今，四川农业大学生命科学学院，教授
2006年至2012年，四川农业大学生命科学与理学院，副教授
2004年至2006年，四川农业大学生命科学与理学院，讲师
◆教育经历
2013年-2014年，美国普渡大学，访问****
2001年-2004年，四川大学，理学博士
1997年-2000年，四川农业大学，农学硕士
1991年-1995年，四川畜牧兽医学院，农学学士
◆获奖荣誉
获四川省科技进步一等奖2项、三等奖1项
◆社会、学会及学术兼职
四川省生物化学与分子生物学学会理事
中国作物学会燕麦荞麦专业委员会会员
◆研究领域
主要从事植物次生代谢调控及抗逆分子机制研究，在苦荞黄酮合成代谢酶学机理研究及转录因子分子调控、苦荞抗逆相关转录因子调控机制研究在领域内处于领先水平。
◆科研项目
1.国家自然科学基金面上项目，**，苦荞转录因子FtMYB22的抗逆分子机制研究，2019/01-2022/12，60万元，主持
2.四川省科技厅国际合作项目，14GH0098，苦荞黄酮合成相关MYB转录因子基因资源的挖掘与利用，2015/01-2016/12，30万元，主持
3.国家自然科学基金青年科学基金项目，**，苦荞黄酮醇合酶FLS同源基因的分子克隆、催化特征及其对芦丁合成的影响，2016/01-2018/12，20万元，主研
4.四川省科技厅国际合作项目，2014HH0012，苦荞米荞一号易脱壳性状的差异蛋白质组研究，2014/01-2015/12，30万元，主研
◆发表论文
26.Hongyou Li#*, Qiuyu Lv#, Ake Liu, Jiarui Wang, Xiaoqian Sun, Jiao Deng,Qingfu Chen*, Qi Wu*. Comparative metabolomics study of Tartary (Fagopyrum tataricum (L.) Gaertn) and common (Fagopyrum esculentum Moench)buckwheat seeds. Food Chemistry,2021, https://doi.org/10.1016/j.foodchem.2021.131125
25.Yingjun Yao#, Lei Sun#, WenJing Wu, Shuang Wang, Xin Xiao, MinLun Hu, ChengLei Li, HaiXia Zhao, Hui Chen, Qi Wu*. Genome?Wide Investigation of Major Enzyme?Encoding Genes in the Flavonoid Metabolic Pathway in Tartary Buckwheat (Fagopyrum tataricum).Journal of Molecular Evolution, 2021, 89:269–286
24.Qixin Dong#, Haixia Zhao#, Yunji Huang, Ying Chen, Min Wan, Zixian Zeng, Panfeng Yao, Chenglei Li, Xiaoli Wang, Hui Chen, Qi Wu*. FtMYB18 acts as a negative regulator of anthocyanin/proanthocyanidin biosynthesis in Tartary buckwheat.Plant Molecular Biology, 2020, https://doi.org/10.1007/s11103-020-01044-5
23.Bingbing Lv#, Qi Wu#, Anhu Wang, Qi Li, Qixin Dong, Jingjing Yang, Haixia Zhao, Xiaoli Wang, Hui Chen, Chenglei Li*. A WRKY transcription factor, FtWRKY46, from Tartary buckwheat improves salt tolerance in transgenic Arabidopsis thaliana. Plant Physiology and Biochemistry, 2020, 147: 43-53
22.Qi Li#, Qi Wu#, Anhu Wang, Bingbing Lv, Qixin Dong, Yingjun Yao, Qiong Wu, Haixia Zhao, Chenglei Li, Hui Chen, Xiaoli Wang*.Tartary buckwheat transcription factor FtbZIP83 improves the drought/salt tolerance of Arabidopsis via an ABA-mediated pathway. Plant Physiology and Biochemistry, 2019, 144: 312-323
21.Yunji Huang#, Qi Wu#, Shuang Wang, Jiaqi Shi, Qixin Dong, Panfeng Yao, Guannan Shi, Shuangxiu Xu, Renyu Deng, Chenglei Li, Hui Chen, Haixia Zhao*. FtMYB8 from Tartary buckwheat inhibits both anthocyanin/Proanthocyanidin accumulation and marginal Trichome initiation. BMC Plant Biology, 2019,19:263
20.Chenglei Li, Haixia Zhao, Maofei Li, Panfeng Yao, Qingqing Li, Xuerong Zhao, Anhu Wang, Hui Chen, Zizhong Tang, Tongliang Bu, Qi Wu*. Validation of reference genes for gene expression studies in tartary buckwheat (Fagopyrum tataricum Gaertn.) using quantitative real-time PCR. Peer J, 2019, 7:e6522 DOI 10.7717/peerj.6522.
19.Renyu Deng, Haixia Zhao, Yuhua Xiao, Yunji Huang, Panfeng Yao, Yunlong Lei, Chenglei Li, Hui Chen, Qi Wu*. Cloning, Characterization, and Expression Analysis of Eight Stress-Related NAC Genes in Tartary Buckwheat.Crop Science, 2019, 59(1): 266-279.
18.Yunji Huang#, Haixia Zhao#, Fei Gao, Panfeng Yao, Renyu Deng, Chenglei Li, Hui Chen, Qi Wu*. A R2R3-MYB transcription factor gene, FtMYB13, from Tartary buckwheat improves salt/drought tolerance in Arabidopsis. Plant Physiology and Biochemistry, 2018, 132: 238–248.
17.Panfeng Yao, Zhaoxia Sun, Chenglei Li, Xuerong Zhao, Maofei Li, Renyu Deng, Yunji Huang, Haixia Zhao, Hui Chen, Qi Wu*. Overexpression of Fagopyrum tataricum FtbHLH2 enhances tolerance to cold stress in transgenic Arabidopsis[J]. Plant Physiol Biochem, 2018, 125: 85-94.
16.Xiaopeng Luo, Haixia Zhao, Panfeng Yao, Qingqing Li, Yunji Huang, Chenglei Li, Hui Chen, Qi Wu*. An R2R3-MYB Transcription Factor FtMYB15 Involved in the Synthesis of Anthocyanin and Proanthocyanidins from Tartary Buckwheat. [J]. Journal of Plant Growth Regulation, 2018, 37(1): 76-84.
15.Yunlong Lei, Peipei Zhao, Chenglei Li, Haixia Zhao, Zhi Shan, Qi Wu*. Isolation, identification and characterization of a novel elastase from Chryseobacterium indologenes[J]. Applied Biological Chemistry, 2018, 61(3): 365-372.
14.Panfeng Yao, Chenglei Li, Xuerong Zhao, Maofei Li, Haixia Zhao, Jinya Guo, Yi Cai, Hui Chen, Qi Wu*. Overexpression of a Tartary Buckwheat Gene,FtbHLH3, Enhances Drought/Oxidative Stress Tolerance in Transgenic Arabidopsis:[J]. Front Plant Sci, 2017, 8:625.
13.Fei Gao, Jing Zhou, Ren-Yu Deng, Hai-Xia Zhao, Cheng-Lei Li, Hui Chen, Tatsuro Suzuki, Sang-Un Park, Qi Wu*. Overexpression of a tartary buckwheat R2R3-MYB transcription factor gene, FtMYB9, enhances tolerance to drought and salt stresses in transgenic Arabidopsis. Journal of Plant Physiology. 2017, 214: 81–90
12.Huipeng Yao, Chenglei Li, Haixia Zhao, Jianlan Zhao, Hui Chen, Tongliang Bu, Wang Anhu, Qi Wu*. Deep sequencing of the transcriptome reveals distinct flavonoid metabolism features of black tartary buckwheat (Fagopyrum tataricum Garetn.). Progress in Biophysics and Molecular Biology. 2017, 124: 49-60.
11.Jing Zhou, Cheng-Lei Li, Fei Gao, Xiao-Peng Luo, Qing-Qing Li, Hai-Xia Zhao, Hui-Peng Yao,Hui Chen, An-Hu Wang, Qi Wu*.Characterization of Three Glucosyltransferase Genes in Tartary Buckwheat and Their Expression after Cold Stress. J. Agric. Food,2016,64:6930-6938
10.Panfeng Yao, Haixia Zhao, Xiaopeng Luo, Fei Gao, Chenglei Li, Huipeng Yao, Hui Chen, SangUn Park, Qi Wu*. Fagopyrum tataricum FtWD40 Functions as a Positive Regulator of Anthocyanin Biosynthesis in Transgenic Tobacco. Journal of Plant Growth Regulation, 2017, 36(3):755-765
9.Fei Gao, Hai-Xia Zhao, Hui-Peng Yao, Cheng-Lei Li, Hui Chen, An-Hu Wang, Sang-Un Park, Qi Wu*. Identification, isolation and expression analysis of eight stressrelated R2R3-MYB genes in tartary buckwheat (Fagopyrum tataricum). Plant Cell Rep, 2016, 35(6): 1385–1396
8.Fei Gao, Hui-Peng Yao, Hai-Xia Zhao, Jing Zhou, Xiao-Peng Luo, Yun-Ji Huang, Cheng-Lei Li, Hui Chen, Qi Wu*. Tartary buckwheat FtMYB10 encodes an R2R3-MYB transcription factor that acts as a novel negative regulator of salt and drought response in transgenic Arabidopsis. Plant Physiology and Biochemistry, 2016, 109: 387-396.
7.Xiaopeng Luo, Haixia Zhao, Jun Xue, Chenglei Li, Hui Chen, Sangun Park, Qi Wu*. Cloning of two basic helix-loop-helix transcription factor genes from Tartary buckwheat (Fagopyrum tataricum) and their expression under abiotic stress. Turk J Biol, 2016, 40: 1192-1201.
6.Panfeng Yao, Haixia Zhao, Xiaopeng Luo, Fei Gao, Huipeng Yao, Hui Chen, Qi Wu*. Chalcone Synthase Homologous Genes Cloning and Expression Pattern in Flowering Fagopyrum tataricum Gaertn. Russian Journal of Plant Physiology, 2016, 63(6): 790–799.
5.Shuangjiang Li, Yuechen Bai, Chenglei Li, Huipeng Yao, Hui Chen, Haixia Zhao, Qi Wu*. Anthocyanins accumulate in tartary buckwheat (Fagopyrum tataricum) sprout in response to cold stress. [J]. Acta Physiologiae Plantarum, 2015, 37(8):1-8.
4.Yuechen Bai, Chenglei Li, Jinwen Zhang, Shuangjiang Li, Xiaopeng Luo, Huipeng Yao, Hui Chen, Haixia Zhao, Sangun Park, Qi Wu*. Characterization of two tartary buckwheat R2R3-MYB transcription factors and their regulation of proanthocyanidin biosynthesis. Physiologia Plantarum. 2014: 431–440.
3.Xiaowei Zhang, Chenglei Li, Qiantao Jiang, Yuming Wei, Huipeng Yao, Hui Chen, Qi Wu*. Cloning and characterization of a cold inducible Pal promoter from Fagopyrum tataricum. Cent. Eur. J. Biol. 2014, 9(3): 290-297.
2.Chenglei Li, Yuechen Bai, Shuangjiang Li, Hui Chen, Xueyi Han, Haixia Zhao, Jirong Shao,Sang-un Park, Qi Wu*. Cloning, Characterization, and Activity Analysis of a Flavonol Synthase Gene FtFLS1 and Its Association with Flavonoid Content in in Tartary Buckwheat. J. Agric. Food,2012,60:5161-5168
1.Chenglei Li, Yuechen Bai, Hui Chen, Haixia Zhao, Jirong Shao, Qi Wu*. Cloning, Characterization and Functional Analysis of a Phenylalanine Ammonia-lyase Gene (FtPAL) from Fagopyrum tataricum Gaertn. Plant Molecular Biology Reporter. [J]. Plant Molecular Biology Reporter, 2012, 30(5):1172-1182.
◆教学活动
主讲，硕士生《分子生物学及实验技术》
主讲，硕士生《植物次生代谢》
主讲，博士生《高级植物分子生物学》
◆我的团队
课题组名称：苦荞黄酮代谢调控与抗逆
课题组负责人：吴琦教授
课题组成员：王晓丽教授、赵海霞副教授、李成磊讲师、吴花拉讲师
课题组在读博士生：南国辉、王磊、王霜、赵佳利
课题组在读硕士生：王利姣、孙磊、陈莹、肖欣、赵晶、李力、方岳、古俊、杨开、胡沐凡、刘琳玲、唐瑜、李辉、马琪涵、李鑫、谢雪梅