陈应春 教授 （博士生导师）
单位：四川大学华西药学院药物化学系
通讯地址：成都市人民南路三段十七号 四川大学华西药学院
电话/传真：（028）**
E-mail: ycchen@scu.edu.cn

简历
1990-1994 天津南开大学化学系有机化学专业 本科
1994-1997 华西医科大学药学院药物化学专业 硕士研究生
1998-2001 中科院成都有机化学研究所有机化学专业 博士研究生
2001-2002 中科院成都有机化学研究所 博士后研究
2002-2003 香港大学化学系 博士后研究
2003-至今　 四川大学华西药学院 教授、博士生导师

研究内容
　　主要从事新型手性催化剂的设计、合成及不对称催化反应研究以及生理活性物质的设计、合成等方面的工作。重点在手性有机小分子催化的不对称合成领域开展研究并获得了系列成果：1）在基于氢键活化的手性硫脲等催化剂的设计及其促进的不对称反应进行了多方面研究，建立了结构、功能多样的基于氢键活化的有机催化剂库，在多种不对称催化反应中实现了好的立体控制，发展了多种重要手性中间体、特别是非天然氨基酸的不对称合成方法。2）在手性伯、仲胺通过烯胺、二烯胺、三烯胺及亚胺盐机制催化饱和或不饱和醛和酮以及叔胺、叔膦等作为Lewis base催化Morita-Baylis-Hillman产物碳酸酯的不对称转化反应等领域开展了系统的研究，在催化剂、催化机制及新型催化反应的设计等多方面进行了积极探索。3）致力于新颖的硫酚/手性胺、硫酚/手性相转移以及硫酚/有机膦等共催化体系的发展，实现了多类具挑战性的不对称反应的区域、化学以及立体选择性的高效调控。4）探索了新型的Lewis碱/金属配合物协同催化体系，进一步拓展了叔膦/叔胺等Lewis碱催化的应用范围。5）课题组建立了数十种多官能团、多手性中心化合物的合成新方法，建立数千个新型化合物库；通过计算机辅助和细胞筛选实验，发现多类新颖的抗肿瘤、抗肺纤维化等新结构物质，为进一步发现和设计新型生理活性手性化合物奠定坚实基础。
　　作为通讯作者已在Chem. Soc. Rev.、Acc. Chem. Res.、Nat. Chem.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、 ACS Cat.等国内外学术期刊上发表SCI论文160余篇，总他引超过7500次。参与《Cinchona Alkaloids in Synthesis & Catalysis: Ligands, Immobilization and Organocatalysis》、《Asymmetric Organocatalysis》、《Organocatalytic Ring-Forming Reactions》等英文专著章节的撰写工作。完成了包括国家Ⅰ类抗癌新药Cambretastatin A-4 水溶性前药、国家Ⅰ类抗脓毒症新药KB甲烷磺酸盐等药物的合成研究（均进入临床研究）。

现主要研究课题
1.国家自然科学基金面上项目：胺催化环状烯酮类化合物的多样性不对称环加成反应。（66万元，2018-2021）
2.科技部第二批****青年领军人才项目
3.中国-波兰国际合作交流项目：路易斯碱催化芳香羰基化合物的不对称反应研究。（140万元，2019-2022）
4.国家自然科学基金重点项目：新型Lewis碱催化体系的发展及相关不对称反应研究。（300万元，2020-2024）
5.国家自然科学基金委创新群体项目。（2020-2024，参与）

获奖情况
1. 2007年 四川省第九届青年科技奖
2. 2007年 药明康德生命化学研究奖（三等）
3. 2011四川省有突出贡献的优秀专家
4. 2011年国家****科学基金
5. 2012 Thieme Journal Award
6. 2012 Asia Core Program Lectureship Award
7. 2013年全国百篇优秀博士学位论文指导教师
8. 2014年中国化学会青年手性化学奖
9. 2014年科技部科技创新人才推进计划青年领军人才
10. 2015年四川省卫生计生领军人才
11. 2016年科技部第二批****青年领军人才

发表论文情况
2020年
1.Shu-Yuan Liang, Bo Jiang, Ben-Xian Xiao, Zhi-Chao Chen, Wei Du, and Ying-Chun Chen,* “Phosphine catalyzed enantioselective cascade reaction initiated by intermolecular cross Rauhut–Currier reaction of electron-deficient ortho-formyl styrenes”, ChemCatChem 2020, DOI: 10.1002/cctc..
2.Chang-Jiang Xu, Wei Du, ?ukasz Albrecht, and Ying-Chun Chen,* “Lewis basic amine-catalyzed aza-Michael reaction of indole- and pyrrole-3-carbaldehydes”, Synthesis 2020, DOI: 10.1055/s-.
3.Guang-Yao Ran, Chen Chen, Xing-Xing Yang, Zhi Zhao, Wei Du,* and Ying-Chun Chen,* “Cu(I)-catalyzed asymmetric α-allenylation of activated ketimines with 3-butynoates”, Org. Lett. 2020, 22, 4732.
4.Bo Jiang, Wei Du,* and Ying-Chun Chen,* “Modified cinchona alkaloid‐catalysed enantioselective [4 + 4] annulations of cyclobutenones and 1-azadienes”, Chem. Commun. 2020, 56, 7257.
5.Ru-Jie Yan, Bao-Xin Liu, Ben-Xian Xiao, Wei Du, and Ying-Chun Chen,* “Asymmetric (4 + 3) and (4 + 1) annulations of isatin-derived Morita?Baylis?Hillman carbonates to construct diverse chiral heterocyclic frameworks”, Org. Lett. 2020, 22, 4240.
6.Peng Chen, Yue Li, Zhi-Chao Chen,* Wei Du, and Ying-Chun Chen,* “Pseudo-stereodivergent synthesis of enantioenriched tetrasubstituted alkenes via cascade 1,3-oxo-allylation/Cope rearrangement”, Angew. Chem. Int. Ed. 2020, 59, 7083.
7.Di Hu, Yang Gao, Xue Song, Wei Du, and Ying-Chun Chen,* “Asymmetric remote addition reactions of heterocycle-based dearomative dienamine or trienamine species to 1-azadienes: Application to construct chiral azocanes and azecanes”, Eur. J. Org. Chem. 2020, 514.
8.Yang Yang, Ying Jiang, Wei Du, and Ying-Chun Chen,* “Asymmetric cross [10+2] cycloaddtions of 2-alkylidene-1-indanones and activated alkenes under phase-transfer catalysis”, Chem. Eur. J. 2020, 26, 1754.
9.Zhi-Chao Chen, Zhi Chen, Wei Du,* and Ying-Chun Chen,* “Transformations of modified Morita–Baylis–Hillman adducts from isatins catalyzed by Lewis bases”, Chem. Rec. 2020, 20, 541.
2019年
1.Zhi-Chao Chen, Zhi Chen, Wei Du,* and Ying-Chun Chen,* "Transformations of modified Morita–Baylis–Hillman adducts from isatins catalyzed by
Lewis bases", Chem. Rec. 2019, accepted.
2.Ben-Xian Xiao, Chong-Hui Shi, Shu-Yuan Liang, Bo Jiang, Wei Du, and Ying-Chun Chen,* "Remote FriedelCrafts reaction with α-heteroaryl-substituted cyclic ketones via HOMO-activation of Lewis bases", Org. Lett. 2019, 21, 7554.
3.Zhi Zhou, Qing He, Ying Jiang, Qin Ouyang, Wei Du,* and Ying-Chun Chen,* "Double thiol-chiral Br?nsted base catalysis: Asymmetric cross RauhutCurrier reaction and sequential [4 + 2] annulation for assembly of different activated olefins", Org. Lett. 2019, 21, 7184.
4.Zhi-Chao Chen, Zhi Chen, Zhen-Hong Yang, Li Guo, Wei Du,* and Ying-Chun Chen,* "Cooperative tertiary amine/chiral iridium complex catalyzed asymmetric [4+3] and [3+3] annulation reactions", Angew. Chem. Int. Ed. 2019, 58, DOI: 10.1002/anie..
5.Chong-Hui Shi, Ben-Xian Xiao, Wei Du, Ying-Chun Chen,* "Phosphine-catalyzed formal [6 + 2] cycloadditions of -methylene 2-cyclopentenones", Chin. J. Org. Chem. 2019, 39, 2218.
6.Lin Chen, Ben-Xian Xiao, Wei Du, and Ying-Chun Chen,* "Quaternary phosphonium salts as active Br?nsted acid catalysts for FriedelCrafts reactions", Org. Lett. 2019, 21, 5733.
7.Guang-Yao Ran, Xing-Xing Yang, Jing-Fei Yue, Wei Du,* and Ying-Chun Chen,* "Asymmetric allylic alkylations with deconjugated carbonyl compounds: Direct vinylogous umpolung strategy", Angew. Chem. Int. Ed. 2019, 58, 9210.
8.Chang-Jiang Xu, Hong-Wei Li, Xiao-Long He, Wei Du, and Ying-Chun Chen,* "Asymmetric direct remote Michael addition reactions of allyl furfurals via dearomative trienamine and tetraenamine catalysis"，Asian J. Org. Chem. 2019, 8, 1037.
9.Bo Jiang, Ben-Xian Xiao, Qin Ouyang, Hua-Ping Liang,* Wei Du, and Ying-Chun Chen,* "Sequential assembly of MoritaBaylisHillman carbonates and activated ortho-vinylbenzaldehydes to construct chiral methanobenzo[7]annulenone frameworks", Org. Lett. 2019, 21, 3310.
10.Xiao-Long He, Hui-Ru Zhao, Xue Song, Bo Jiang, Wei Du,* and Ying-Chun Chen,* "Asymmetric BartonZard reaction to access 3-pyrrole-containing axially chiral skeletons", ACS Catal. 2019, 9, 4374.
11.Rong Zeng, Changyu Shan, Ming Liu, Kun Jiang,* Ying Ye, Tian-Yu Liu, Ying-Chun Chen,* "[4 + 1 + 1] Annulations of -bromo carbonyls and 1-azadienes towards fused benzoazaheterocycles", Org. Lett. 2019, 21, 2312.
12.Ben-Xian Xiao, Bo Jiang, Xue Song, Wei Du, and Ying-Chun Chen,* "Phosphine-catalysed asymmetric dearomative formal [4 + 2] cycloadditions of 3-benzofuranyl vinyl ketones", Chem. Commun. 2019, 55, 3097.
13.Peng Chen, Zhi-Chao Chen, Yue Li, Qin Ouyang, Wei Du,* and Ying-Chun Chen,* "Auto-tandem cooperative catalysis using phosphine/palladium: Reaction of MoritaBaylisHillman carbonates and allylic alcohols", Angew. Chem. Int. Ed. 2019, 58, 4036.
14.Qian-Qian Yang, Xiang Yin, Xiao-Long He, Wei Du,* and Ying-Chun Chen,* "Asymmetric formal [5 + 3] cycloadditions with unmodified MoritaBaylisHillman alcohols via double activation catalysis", ACS Catal. 2019, 9, 1258.
15.Jing Gu, Ben-Xian Xiao, Qin Ouyang,* Wei Du, and Ying-Chun Chen,* "Phosphine-catalyzed interrupted MoritaBaylisHillman reaction and switchable domino reactions of -substituted activated olefins with formaldehyde and mechanism elucidation", Chin. J. Chem. 2019, 37, 155.
16.Ben-Xian Xiao, Xin-Yue Gao, Wei Du,* and Ying-Chun Chen,* "Asymmetric reactions involving Lewis Base catalyst-tethered dearomatizative intermediates", Chem. Eur. J. 2019, 25, 1607.
2018年
17.Ru-Jie Yan, Ben-Xian Xiao, Qin Ouyang, Hua-Ping Liang,* Wei Du, and Ying-Chun Chen,* "Asymmetric dearomative formal [4 + 2] cycloadditions of N,4-dialkylpyridinium salts and enones to construct azaspiro[5.5]undecane frameworks", Org. Lett. 2018, 20, 8000.
18.Zhi-Chao Chen, Peng Chen, Zhi Chen, Qin Ouyang, Hua-Ping Liang,* Wei Du, and Ying-Chun Chen,* "Organocatalytic enantioselective 1,3-difunctionalizations of MoritaBaylisHillman carbonates", Org. Lett. 2018, 20, 6279.
19.Jing-Fei Yue, Guang-Yao Ran, Xing-Xing Yang, Wei Du,* and Ying-Chun Chen,* "Asymmetric DielsAlder cycloadditions of benzofulvene-based 2,4-dienals via trienamine activation", Org. Chem. Front. 2018, 5, 2676.
20.Wei Xiao, Zhi Zhou, Qian-Qian Yang, Wei Du,* and Ying-Chun Chen,* "Organocatalytic asymmetric four-component [5+1+1+1] cycloadditions via a quintuple cascade process", Adv. Synth. Catal. 2018, 360, 3526.
21.Yuanchun Zhou, Zhi Zhou, Wei Du,* Yingchun Chen,* "Asymmetric inverse-electron-demand DielsAlder reaction of 2-pyrone and 2,5-dienones via HOMO-activation", Acta Chim. Sinica 2018, 76, 382.
22.Chuan-Qi Duan, Xiao-Long He, Wei Du,* and Ying-Chun Chen,* "Asymmetric [4 + 2] cycloadditions with 3-furfural derivatives and -cyano-,-unsaturated ketones", Org. Chem. Front. 2018, 5, 2057.
23.Xiao-Long He, Hui-Ru Zhao, Chuan-Qi Duan, Xu Han, Wei Du, and Ying-Chun Chen,* "Asymmetric benzylic allylic alkylation reaction of 3-furfural derivatives via dearomatizative dienamine activation", Chem. Eur. J. 2018, 24, 6277.
24.Jing Gu, Ben-Xian Xiao, Yu-Rong Chen, Qing-Zhu Li, Qin Ouyang,* Wei Du, and Ying-Chun Chen,* "Interrupted MoritaBaylisHillman-type reaction of -substituted activated olefins", Org. Lett. 2018, 20, 2088.
25.Xiao-Long He, Hui-Ru Zhao, Chuan-Qi Duan, Wei Du and Ying-Chun Chen,* "Remote asymmetric oxa-DielsAlder reaction of 5-allylic furfurals via dearomatizative tetraenamine catalysis", Org. Lett. 2018, 20, 804.
26.Qian-Qian Yang, Wei Xiao, Wei Du, Qin Ouyang, and Ying-Chun Chen,* "Asymmetric [4 + 2] annulations to construct norcamphor scaffolds with 2-cyclopentenone via double amine-thiol catalysis", Chem. Commun. 2018, 54, 1129.
27.Wei Xiao, Qian-Qian Yang, Zhi Chen, Qin Ouyang,* Wei Du, and Ying-Chun Chen,* "Regio- and diastereodivergent [4 + 2] cycloadditions with cyclic 2,4-dienones", Org. Lett. 2018, 20, 236.
2017年
28.Qing He, Wei Du, and Ying-Chun Chen,* "Asymmetric [3+2] annulations to construct 1,2-bispirooxindoles incorporating a dihydropyrrolidine motif", Adv. Synth. Catal. 2017, 359, 3782.
29.Minglin Shi, Gu Zhan, Wei Du,* Yingchun Chen,* "Direct asymmetric aza-vinylogous Mannich reaction of nitrones from isatins and ketimines", Acta Chim. Sinica 2017, 75, 998.
30.Ben-Xian Xiao, Ru-Jie Yan, Xin-Yue Gao, Wei Du, and Ying-Chun Chen,* "Asymmetric benzylic functionalizations of 3-vinyl benzofurans via cascade formal trienaminevinylogous iminium ion activation", Org. Lett. 2017, 19, 4652.
31.Zhou-Xiang Wang, Zhi Zhou, Wei Xiao, Qin Ouyang, Wei Du, and Ying-Chun Chen,* "Double activation catalysis for -alkylidene cyclic enones with chiral amines and thiols", Chem. Eur. J. 2017, 23, 10678.
32.Chao Li, Kun Jiang, Tian-Yu Liu,* and Ying-Chun Chen,* "Asymmetric [4+1] cycloadditions of N-thioacyl Imines and sulfur ylides", Adv. Synth. Catal. 2017, 359, 2530.
33.Xiao-Ru Zhang, Su-Lan Zhou, Yi Yuan, Wei Du, and Ying-Chun Chen,* "Chemo- and regioselective asymmetric FriedelCrafts reaction of furans and thiophenes with ,-unsaturated aldehydes through dual activation", Synlett 2017, 28, 1771.
34.Gu Zhan, Ming-Lin Shi, Wei-Jia Lin, Qin Ouyang, Wei Du,* and Ying-Chun Chen,* "Direct asymmetric aza-vinylogous-type Michael additions of nitrones from isatins to nitroalkenes", Chem. Eur. J. 2017, 23, 6286.
35.Guang-Yao Ran, Ming Gong, Jing-Fei Yue, Xing-Xing Yang, Su-Lan Zhou, Wei Du, and Ying-Chun Chen,* "Asymmetric cascade assembly of 1,2-diaza-1,3-dienes and α,β-unsaturated aldehydes via dienamine activation", Org. Lett. 2017, 19, 1874.
36.Gu Zhan, Wei Du, Ying-Chun Chen,* "Switchable divergent asymmetric synthesis via organocatalysis", Chem. Soc. Rev. 2017, 46, 1675.
37.Ben-Xian Xiao, Wei Du, and Ying-Chun Chen,* "Asymmetric dearomatizative DielsAlder reaction for the construction of hydrodibenzo[b,d]furan frameworks with tetrasubstituted stereogenic centers", Adv. Synth. Catal. 2017, 359, 1018.
38.Wei-Jia Lin, Gu Zhan, Ming-Lin Shi, Wei Du,* and Ying-Chun Chen,* "[3+3] formal cycloadditions of nitrones from isatins and azaoxyallyl cations for construction of spirooxindoles", Chin. J. Chem. 2017, 35, 857.
39.Zhi Zhou, Zhou-Xiang Wang, Qin Ouyang, Wei Xiao, Wei Du, and Ying-Chun Chen,* "Cross-conjugated trienamine catalysis with -alkylidene 2-cyclohexenones: application in ,-regioselective aza-DielsAlder reaction", Chem. Eur. J. 2017, 23, 2945.
40.Zhi Zhou, Zhou-Xiang Wang, Yuan-Chun Zhou, Wei Xiao, Qin Ouyang,* Wei Du, Ying-Chun Chen,* "Switchable regioselectivity in amine-catalysed asymmetric cycloadditions", Nat. Chem. 2017, 9, 590.
41.Kai-Kai Wang, Wei Du, Jin Zhu, Ying-Chun Chen,* "Construction of polycyclic spirooxindoles through [3+2] annulations of Morita?Baylis?Hillman carbonates and 3-nitro-7-azaindoles", Chin. Chem. Lett. 2017, 28, 512.
2016年
42.Ming-Lin Shi, Gu Zhan, Su-Lan Zhou, Wei Du, and Ying-Chun Chen,* "Asymmetric inverse-electron-demand oxa-DielsAlder reaction of allylic ketones through dienamine catalysis", Org. Lett. 2016, 18, 6480.
43.Yu-Rong Chen, Gu Zhan, Wei Du,* and Ying-Chun Chen,* "Regioselective asymmetric formal (3+2) cycloadditions of nitrone ylides from isatins and enals", Adv. Synth. Catal. 2016, 358, 3759.
44.Guang-Jun Yang, Wei Du, and Ying-Chun Chen,* "Construction of furan derivatives with a trifluoromethyl stereogenic center: Enantioselective Friedel–Crafts alkylations via formal trienamine catalysis", J. Org. Chem. 2016, 81, 10056.
45.Kai-Kai Wang, Pan Wang, Qin Ouyang,* Wei Du, and Ying-Chun Chen,* "Substrate-controlled switchable asymmetric annulations to access polyheterocyclic skeletons", Chem. Commun. 2016, 52, 11104.
46.Xin Yuan, Shan-Jun Zhang, Wei Du, and Ying-Chun Chen,* "Asymmetric Diels–Alder cycloadditions of trifluoromethylated dienophiles via trienamine catalysis", Chem. Eur. J. 2016, 22, 11048.
47.Chao Li, Kun Jiang, Qin Ouyang, Tian-Yu Liu,* and Ying-Chun Chen,* "[3 + 1]- and [3 + 2]-Cycloadditions of azaoxyallyl cations and sulfur ylides", Org. Lett. 2016, 18, 2738.
48.Guang-Yao Ran, Pan Wang, Wei Du, and Ying-Chun Chen,* "α-Regioselective [3 + 2] annulations with MoritaBaylisHillman carbonates of isatins and 2-nitro-1,3-enynes", Org. Chem. Front. 2016, 3, 861.
49.Qing He, Gu Zhan, Wei Du and Ying-Chun Chen,* "Application of 7-azaisatins in enantioselective Morita–Baylis–Hillman reaction", Beilstein J. Org. Chem. 2016, 12, 309.
50.Kai-Kai Wang, Tian Jin, Xin Huang, Qin Ouyang,* Wei Du, and Ying-Chun Chen,* "-Regioselective asymmetric [3 + 2] annulations of Morita?Baylis?Hillman carbonates with cyclic 1-azadienes and mechanism elucidation", Org. Lett. 2016, 18, 872.
51.Jing Gu, Ben-Xian Xiao, Yu-Rong Chen, Wei Du, and Ying-Chun Chen,* "Asymmetric DielsAlder and cascade reaction of quinone imine ketals and 2,4-dienals: Construction of chiral benzo[de]quinolone derivatives", Adv. Synth. Catal. 2016, 358, 296.
52.Gu Zhan, Ming-Lin Shi, Qing He, Wei-Jia Lin, Qin Ouyang,* Wei Du, and Ying-Chun Chen,* "Catalyst-controlled switch in chemo- and diastereoselectivities: Annulations of MoritaBaylisHillman carbonates from isatins", Angew. Chem. Int. Ed. 2016, 55, 2147.
53.Wei Xiao, Xiang Yin, Zhi Zhou, Wei Du, and Ying-Chun Chen,* "Asymmetric ,-regioselective [3 + 3] formal cycloadditions of ,-unsaturated aldehydes via cascade dienaminedienamine catalysis", Org. Lett. 2016, 18, 116.
2015年
54.Jing Gu, Wei Du, and Ying-Chun Chen,* "Combined asymmetric aminocatalysis and carbene catalysis", Synthesis 2015, 47, 3451.
55.Gu Zhan, Ming-Lin Shi, Qing He, Wei Du, and Ying-Chun Chen,* "[4 + 3] Cycloadditions with bromo-substituted Morita?Baylis?Hillman adducts of isatins and N-(ortho-chloromethyl)aryl amides", Org. Lett. 2015, 17, 4750.
56.Jing Peng, Guang-Yao Ran, Wei Du, and Ying-Chun Chen,* "Divergent cyclization reactions of MoritaBaylisHillman carbonates of 2-cyclohexenone and isatylidene malononitriles", Org. Lett. 2015, 17, 4490.
57.Chao Li, Kun Jiang,* and Ying-Chun Chen,* "Diastereodivergent and enantioselective [4+2] annulations of γ-butenolides with cyclic 1-azadienes", Molecules 2015, 20, 13642.
58.Peng-Fei Zheng, Qin Ouyang, Sheng-Li Niu, Li Shuai, Yi Yuan, Kun Jiang, Tian-Yu Liu,* and Ying-Chun Chen,* "Enantioselective [4+1] annulation reactions of -substituted ammonium ylides to construct spirocyclic oxindoles", J. Am. Chem. Soc. 2015, 137, 9390.
59.Jing Peng, Guang-Yao Ran, Wei Du, and Ying-Chun Chen,* "Tertiary amine-catalyzed asymmetric [3+2] annulations of MoritaBaylisHillman carbonates of isatins with nitroolefins to construct spirooxindoles", Synthesis 2015, 47, 2538.
60.Xiao-Long He, You-Cai Xiao, Wei Du, and Ying-Chun Chen,* "Enantioselective formal [3 + 3] cycloadditions of ketones and cyclic 1-azadienes via cascade enamine-enamine catalysis", Chem. Eur. J. 2015, 21, 3443.
61.Kun, Jiang, and Ying-Chun Chen,* "The development of asymmetric trienamine catalysis", Prog. Chem. 2015, 27, 137.
2014年
62.Gu Zhan, Qing He, Xin Yuan, and Ying-Chun Chen,* "Asymmetric direct vinylogous Michael additions of allyl alkyl ketones to maleimides through dienamine catalysis", Org. Lett. 2014, 16, 6000.
63.Gu Zhan, Qing-Qing Zhou, Wei Du, and Ying-Chun Chen,* "Enantioselective N-allylic alkylation of propargyl sulfonamides with MoritaBaylisHillman carbonates and sequential electrophilic cyclization", Synthesis 2014, 46, 3383.
64.Xin Feng, Zhi Zhou, Xiang Yin, Rui Li,* and Ying-Chun Chen,* "Enantioselective direct bisvinylogous 1,6-additions of -allyl 2-cyclohexenone to ,-dicyanodienes through trienamine catalysis", Eur. J. Org. Chem. 2014, 5906.
65.Qing-Zhu Li, Jing Gu, and Ying-Chun Chen,* "Organocatalytic asymmetric [4+2] formal cycloadditions of cyclohexenylidenemalononitriles and enals to construct chiral bicyclo[2.2.2]octanes", RSC Adv. 2014, 4, 37522.
66.Jing Gu, Chao Ma, Qing-Zhu Li, Wei Du, and Ying-Chun Chen,* "β,γ-Regioselective inverse-electron-demand aza-DielsAlder reactions with α,β-unsaturated aldehydes via dienamine catalysis", Org. Lett. 2014, 16, 3986.
67.Rong Zhou, Wei Xiao, Xiang Yin, and YingChun Chen,* "Diastereo- and enantioselective [4+2] cycloadditions of cyclic enones with cyclic 1-azadienes", Acta Chim. Sinica 2014, 72, 862.
68.You-Cai Xiao, Cai-Zhen Yue, Peng-Qiao Chen, and Ying-Chun Chen,* "Asymmetric dearomatic DielsAlder reactions of diverse heteroarenes via -system activation", Org. Lett. 2014, 16, 3208.
69.Xiang Yin, Yi Zheng, Xin Feng, Kun Jiang, Xue-Zhen Wei, Ning Gao,* and Ying-Chun Chen,* "Asymmetric [5 + 3] formal cycloadditions with cyclic enones through cascade dienamine-dienamine catalysis", Angew. Chem. Int. Ed. 2014, 53, 6245.
70.Jun-Long Li, Cai-Zhen Yue, Peng-Qiao Chen, You-Cai Xiao, and Ying-Chun Chen,* "Remote enantioselective FriedelCrafts alkylations of furans via HOMO-activation", Angew. Chem. Int. Ed. 2014, 53, 5449.
71.Zhi Zhou, Xin Feng, Xiang Yin, and Ying-Chun Chen,* "Direct remote asymmetric bisvinylogous 1,4-additions of cyclic 2,5-dienones to nitroalkenes", Org. Lett. 2014, 16, 2370.
72.Peng-Qiao Chen, You-Cai Xiao, Cai-Zhen Yue, and Ying-Chun Chen,* "Trienamine catalysis with linear deconjugated 3,5-dienones", Org. Chem. Front. 2014, 1, 490.
73.Qing-Qing Zhou, You-Cai Xiao, Xin Yuan, and Ying-Chun Chen,* "Asymmetric DielsAlder reactions of 2,4,6-trienals via tetraenamine catalysis", Asian J. Org. Chem. 2014, 3, 545.
74.Kun Jiang,* Ying-Chun Chen,* "Organocatalytic reactions involving nitrogen-ylides", Tetrahedron Lett. 2014, 55, 2049.
2013年
75.Xin Feng, Zhi Zhou, Chao Ma, Xiang Yin, Rui Li,* Lin Dong, and Ying-Chun Chen,* "Trienamines derived from interrupted cyclic 2,5-dienones: remote δ,?-C=C bond activation for asymmetric inverse-electron-demand aza-DielsAlder reaction", Angew. Chem. Int. Ed. 2013, 52, 14173.
76.Chao Ma, Jing Gu, Bin Teng, Qing-Qing Zhou, Rui Li,* and Ying-Chun Chen,* "1-Azadienes as regio- and chemoselective dienophiles in aminocatalytic asymmetric Diels–Alder reaction", Org. Lett. 2013, 15, 6206.
77.Qing-Qing Zhou, Xin Yuan, You-Cai Xiao, Lin Dong, and Ying-Chun Chen* "Aminocatalytic asymmetric Diels-Alder reaction of phosphorus dienophiles and 2,4-dienals", Tetrahedron 2013, 69, 10369.
78.Jing-Xin Liu, Qing-Qing Zhou, Jin-Gen Deng, and Ying-Chun Chen,* "An asymmetric normal-electron-demand aza-Diels– Alder reaction via trienamine catalysis", Org. Biomol. Chem. 2013, 11, 8175.
79.Jing Peng, Xin Huang, Peng-Fei Zheng, and Ying-Chun Chen,* "RauhutCurrier-type reaction with MoritaBaylisHillman carbonates of 2-cyclohexenone and alkylidenemalononitriles to access chromene derivatives", Org. Lett. 2013, 15, 5534.
80.Quan-Gang Wang, Qing-Qing Zhou, Jin-Gen Deng, and Ying-Chun Chen,* "An asymmetric allylic alkylation-Smiles rearrangement-sulfinate addition sequence to construct chiral cyclic sulfones", Org. Lett. 2013, 15, 4786.
81.Zhi-Jun Jia, Kun Jiang, Qing-Qing Zhou, Lin Dong, Ying-Chun Chen*, "Amine/N-heterocyclic carbene cascade catalysis for asymmetric synthesis of fused indane derivatives with multiple chiral centres, Chem. Commun. 2013, 49, 5892.
82.Yuan Yao, Jun-Long Li, Qing-Qing Zhou, Lin Dong, Ying-Chun Chen,* "Enantioselective aza-MoritaBaylisHillman reaction with ketimines and acrolein catalyzed by organic assemblies", Chem. Eur. J. 2013, 19, 9447.
83.Shan-Jun Zhang, Jun Zhang, Qing-Qing Zhou, Lin Dong, and Ying-Chun Chen,* "Aminocatalytic asymmetric exo-DielsAlder reaction with methiodide salts of Mannich bases and 2,4-dienals to construct chiral spirocycles", Org. Lett. 2013, 15, 968.
84.Chao Ma, Zhi-Jun Jia, Jing-Xin Liu, Qing-Qing Zhou, Lin Dong, and Ying-Chun Chen,* "A concise assembly of electron-deficient 2,4-dienes and 2,4-dienals: regio- and stereoselective exo-DielsAlder and redox reaction via sequential amine and carbene catalysis", Angew. Chem. Int. Ed. 2013, 52, 948.
2012年
85.You-Cai Xiao, Qing-Qing Zhou, Lin Dong, Tian-Yu Liu, and Ying-Chun Chen,* "Asymmetric DielsAlder reaction of 2-methyl-3-indolylmethanols via in situ generation of ortho-quinodimethanes", Org. Lett. 2012, 14, 5940.
86.Xin Feng, Zhi Zhou, Rong Zhou, Qing-Qing Zhou, Lin Dong, and Ying-Chun Chen,* "Stereodivergence in amine-catalyzed regioselective [4+2] cycloadditions of beta-substituted cyclic enones and polyconjugated malononitriles", J. Am. Chem. Soc. 2012, 134, 19942.
87.Xiang Yin, Qingqing Zhou, Lin Dong, Yingchun Chen,* "Asymmetric sequential aza-Diels-Alder and O-Michael addition: efficient construction of chiral hydropyrano[2,3-b]pyridines", Chin. J. Chem. 2012, 30, 2669.
88.Xunhao Sun, Jing Peng, Shuyang Zhang, Qingqing Zhou, Lin Dong, Yingchun Chen,* "Asymmetric allylic alkylation of cyclic N-sulfonylimines with Morita–Baylis–Hillman carbonates of isatins", Acta Chimi. Sinica 2012, 70, 1682.
89.Hang Zhang, Shan-Jun Zhang, Qing-Qing Zhou, Lin Dong, and Ying-Chun Chen*, "Organocatalytic asymmetric allylic amination of MoritaBaylisHillman carbonates of isatins", Beilstein J. Org. Chem. 2012, 8, 1241.
90.Jun-Long, Li, Tian-Yu, Liu, and Ying-Chun Chen,* "Aminocatalytic asymmetric DielsAl
der reactions via HOMO activation", Acc. Chem. Res. 2012, 45, 1491.
91.Tian-Yu Liu, Min Xie, and Ying-Chun Chen,* "Organocatalytic asymmetric transformations of modified MoritaBaylisHillman adducts", Chem. Soc. Rev. 2012, 41, 4101.
92.Qing-Zhu Li, Lei Ma, Lin Dong, and Ying-Chun Chen,* "Asymmetric aza-DielsAlder and cation-olefin cyclization sequence: a concise way to fused chiral cyclopenta[b]piperidines", ChemCatChem 2012, 4, 1139.
93.Jun-Long Li, Si-Li Zhou, Peng-Qiao Chen, Lin Dong, Tian-Yu Liu, and Ying-Chun Chen,* "Asymmetric DielsAlder reaction of ,-disubstituted enals and chromone-fused dienes: construction of collections with high molecular complexity and skeletal diversity", Chem. Sci. 2012, 3, 1879.
94.Xiao-Feng Xiong, Quan Zhou
, Jing Gu, Lin Dong, Tian-Yu Liu, and Ying-Chun Chen,* "Trienamine catalysis with 2,4-dienones: development and application in asymmetric DielsAlder reaction", Angew. Chem. Int. Ed. 2012, 51, 4401.
95.Xin Huang, Jin Peng, Lin Dong, and Ying-Chun Chen,* "Asymmetric assembly of 2-oxindole and -angelica lactone units to construct vicinal quaternary chiral centers", Chem. Commun. 2012, 48, 2439.
2011年
96.Bo Han, Jun-Long Li, You-Cai Xiao, Si-Li Zhou, and Ying-Chun Chen,* "Thiourea-catalyzed asymmetric Mannich-type reactions", Curr. Org. Chem. 2011, 15, 4128.
97.Hai-Lei Cui, Xun-Hao Sun, Lin Jiang, Lin Dong, and Ying-Chun Chen,* "Lewis base-assisted Br?nsted base catalysis: direct asymmetric allylic alkylation of indenes", Eur. J. Org. Chem. 2011, 7366.
98.Si-Li Zhou, Jun-Long Li, Lin Dong, and Ying-Chun Chen,* "Organocatalytic sequential hetero-DielsAlder and FriedelCrafts reaction: constructions of fused heterocycles with scaffold diversity", Org. Lett. 2011, 13, 5874.
99.You-Cai Xiao, Chao Wang, Yuan Yao, Jian Sun,* and Ying-Chun Chen,* "Direct asymmetric hydrosilylation of indoles: Combined Lewis base and Br?nsted acid activation", Angew. Chem. Int. Ed. 2011, 50, 10661.
100.Jing Peng, Xin Huang, Lin Jiang, Hai-Lei Cui, and Ying-Chun Chen,* "Tertiary amine-catalyzed chemoselective and asymmetric [3 + 2] annulation of MoritaBaylisHillman carbonates of isatins with propargyl sulfones", Org. Lett. 2011, 13, 4584.
101.Zhi-Jun Jia, Quan Zhou, Qing-Qing Zhou, Peng-Qiao Chen, and Ying-Chun Chen,* "Exo-selective asymmetric DielsAlder reaction of 2,4-dienals and nitroalkenes via trienamine catalysis", Angew. Chem., Int. Ed. 2011, 50, 8638.
102.Lin Jiang, Qian Lei, Xin Huang, Hai-Lei Cui, Xue Zhou, and Ying-Chun Chen,* "Lewis base assisted Br?nsted base catalysis: direct regioselective asymmetric vinylogous alkylation of allylic sulfones", Chem. Eur. J. 2011, 17, 9489.
103.Zhi-Jun Jia, Hao Jiang, Jun-Long Li, Bj?rn Gschwend, Qing-Zhu Li, Xiang Yin, Julie Grouleff, Ying-Chun Chen,* and Karl Anker J?rgensen,* "Trienamines in asymmetric organocatalysis: Diels-Alder and cascade reactions", J. Am. Chem. Soc. 2011, 133, 5053.
104.Ji-Rong Huang, Hai-Lei Cui, Jie Lei, Xun-Hao Sun, and Ying-Chun Chen,* "Organocatalytic chemoselective asymmetric N-allylic alkylation of enamides", Chem. Commun. 2011, 47, 4784.
105.Lin Jiang, and Ying-Chun Chen,* a review, "Recent advance in asymmetric catalysis with cinchona alkaloid-based primary amines", Catal. Sci. Technol. 2011, 1, 354.
106.Jing Peng, Hailei Cui, and Yingchun Chen,* "Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates", Science China: Chemistry 2011, 54, 81.
107.Xiao-Feng Xiong, Hang Zhang, Jing Peng, and Ying-Chun Chen,* "Direct asymmetric Michael addition of cyclic N-sulfonylimines to ,-unsaturated aldehydes", Chem. Eur. J. 2011, 17, 2358.
2010年
108.Bo Han, You-Cai Xiao, Yuan Yao, Ying-Chun Chen,* "Lewis acid-catalyzed intramolecular direct ene reaction of indoles", Angew. Chem., Int. Ed. 2010, 49, 10189.
109.Jing Peng, Xin Huang, Hai-Lei Cui, Ying-Chun Chen,* "Organocatalytic and electrophilic approach to oxindoles with C3-quaternary stereocenters", Org. Lett. 2010, 12, 4260.
110.Jun-Long Li, Tai-Ran Kang, Si-Li Zhou, Rui Li, Li Wu, Ying-Chun Chen,* "Organocatalytic asymmetric inverse-electron-demand DielsAlder reaction of electron-deficient dienes and crotonaldehyde", Angew. Chem., Int. Ed. 2010, 49, 6418.
111.Zhao-Quan He, Quan Zhou, Li Wu, and Ying-Chun Chen,* "Asymmetric organocatalytic tandem reaction to chiral pyrimidinone derivatives using urea as dinitrogen source", Adv. Synth. Catal. 2010, 352, 1904.
112.Xin Feng, Hai-Lei Cui, Shi Xu, Li Wu, and Ying-Chun Chen,* "Organocatalytic direct vinylogous Michael addition of ,-unsaturated -butyrolactam to ,-unsaturated aldehydes and an illustration to scaffold diversity synthesis", Chem. Eur. J. 2010, 16, 10309.
113.Hailei Cui, Kun Jiang, Yankai Liu, Wei Du, Yingchun Chen,* "Enantioselective direct aldol-type reaction of 4-hydroxycoumarin with ethyl trifluoropyruvate catalyzed by modified cinchona alkaloids", Chin. Sci. Bull. 2010, 55, 1732.
114.Kun Jiang, Zhi-Jun Jia, Xiang Yin, Li Wu, and Ying-Chun Chen,* "Asymmetric quadruple aminocatalytic domino reactions to fused carbocycles incorporating a spirooxindole motif", Org. Lett. 2010, 12, 2766.
115.Jie Lei, Hai-Lei Cui, Rui Li,* Li Wu, Zheng-Yu Ding and Ying-Chun Chen,* "Tributyltin hydride-mediated radical cyclisation reactions: efficient construction of multiply substituted cyclopentanes", Org. Biomol. Chem. 2010, 8, 2840.
116.Jun-Long Li, Si-Li Zhou, Bo Han, Li Wu, and Ying-Chun Chen,* "Aminocatalytic asymmetric inverse-electron-demand aza-Diels–Alder reaction of N-Ts-1-aza-1,3-butadienes based on coumarin cores", Chem. Commun. 2010, 46, 2665.
117.Hai-Lei Cui, Ji-Rong Huang, Jie Lei, Zhao-Feng Wang, Shi Chen, Li Wu, and Ying-Chun Chen,* "Direct asymmetric allylic alkylation of butenolides with Morita-Baylis-Hillman carbonates", Org. Lett. 2010, 12, 720.
118.Kun Jiang, Zhi-Jun Jia, Shi Chen, Li Wu, and Ying-Chun Chen,* "Organocatalytic tandem reaction to construct six-membered spirocyclic oxindoles with multiple chiral centres via a formal [2+2+2] annulation", Chem. Eur. J. 2010, 16, 2852.
119.Zhao-Quan He, Bo Han, Rui Li,* Li Wu, and Ying-Chun Chen,* "Enantioselective construction of lactone[2,3-b]piperidine skeletons via organocatalytic tandem reactions", Org. Biomol. Chem. 2010, 8, 755.
2009年
120.Xiao-Feng Xiong, Zhi-Jun Jia, Wei Du, Kun Jiang, Tian-Yu Liu, and Ying-Chun Chen,* "Merging chiral organocatalysts: enantio- and diastereoselective direct vinylogous Mannich reaction of alkylimines", Chem. Commun. 2009, 6994.
121.Bo Han, You-Cai Xiao, Zhao-Quan He, and Ying-Chun Chen,* "Asymmetric Michael addition of ,-disubstituted ,-unsaturated aldehydes to nitroolefins via dienamine catalysis", Org. Lett. 2009, 11, 4660.
122.Shan-Jun Zhang, Hai-Lei Cui, Kun Jiang, Rui Li,* Zhen-Yu Ding, and Ying-Chun Chen,* "Enantioselective allylic amination of Morita-Baylis-Hillman carbonates catalyzed by modified cinchona alkaloids", Eur. J. Org. Chem. 2009, 5804.
123.ZeKai Hu, HaiLei Cui, Kun Jiang, YingChun Chen*, "Enantioselective O-allylic alkylation of Morita-Baylis-Hillman carbonates with oxime", Sci. China Ser. B: Chem. 2009, 52, 1309.
124.Xin Feng, Yu-Qing Yuan, Hai-Lei Cui, Kun Jiang, and Ying-Chun Chen,* "Organocatalytic peroxy-asymmetric allylic alkylation", Org. Biomol. Chem. 2009, 7, 3660.
125.Hai-Lei Cui, Xin Feng, Jing Peng, Jie Lei, Kun Jiang, and Ying-Chun Chen,* "Chemoselective asymmetric N-allylic alkylation of indoles with Morita-Baylis-Hillman carbonates", Angew. Chem., Int. Ed. 2009, 48, 5737.
126.Bo Han, Zhao-Quan He, Jun-Long Li, Rui Li, Kun Jiang, Tian-Yu Liu, and Ying-Chun Chen,* "Organocatalytic regio- and stereoselective inverse-electron-demand aza-Diels-Alder reaction of ,-unsaturated aldehydes and N-Tosyl-1-aza-1,3-butadienes", Angew. Chem., Int. Ed. 2009, 48, 5474.
127.Yan-Kai Liu, Chao Ma, Kun Jiang, Tian-Yu Liu, and Ying-Chun Chen,* "Asymmetric tandem Michael addition-Wittig reaction to cyclohexenone annulation", Org. Lett. 2009, 11, 2848.
128.Kun Jiang, Jing Peng, Hai-Lei Cui, and Ying-Chun Chen,* "Organocatalytic asymmetric allylic alkylation of oxindoles with Morita-Baylis-Hillman carbonates", Chem. Commun. 2009, 3955.
129.Hai-Lei Cui, Ying-Chun Chen,* a Feature Article, "alfa,alfa-Dicyanoalkenes: versatile vinylogous nucleophiles for organic synthesis", Chem. Commun. 2009, 4479.
130.Jun-Long Li, Bo Han, Kun Jiang, Wei Du, and Ying-Chun Chen,* "Organocatalytic enantioselective hetero-Diels-Alder reaction of aldehydes and o-benzoquinone diimide: Synthesis of optically active hydroquinoxalines", Bioorg. Med. Chem. Lett. 2009, 19, 3952.
131.Hai-Lei Cui, Jing Peng, Xin Feng, Wei Du, Kun Jiang, and Ying-Chun Chen,* "Dual organocatalysis: Asymmetric allylic-allylic alkylation of ,-dicyanoalkenes and Morita-Baylis-Hillman carbonates", Chem. Eur. J. 2009, 15, 1574.
2008年
132.Bo Han, Jun-Long Li, Chao Ma, Shan-Jun Zhang, and Ying-Chun Chen,* "Organocatalytic asymmetric inverse electron demand aza Diels-Alder reaction of N-sulfonyl-1-aza-1,3-butadienes and aldehydes", Angew. Chem., Int. Ed. 2008, 47, 9971.
133.Wei Du, Yan-Kai Liu, Lei Yue, and Ying-Chun Chen,* "Organocatalytic asymmetric 1,3-dipolar cycloaddition of nitrones to nitroolefins", Synlett 2008, 2997.
134.Yan-Kai, Liu, Hao Liu, Wei Du, Lei Yue, and Ying-Chun Chen,* "Reaction control in the organocatalytic asymmetric one pot, three-component reaction of aldehydes, diethyl -aminomalonate and nitroalkenes: toward diversity-oriented synthesis", Chem. Eur. J. 2008, 14, 9873.
135.Bo Han, Qing-Ping Liu, Rui Li, Xu Tian, Xiao-Feng Xiong, Jin-Gen Deng, and Ying-Chun Chen,* "Discovery of bifunctional thiourea-secondary amine organocatalysts for the highly stereoselective nitro-Mannich reaction of -substituted nitroacetates", Chem. Eur. J. 2008, 14, 8094.
136.Xu Tian, Kun Jiang, Jing Peng, Wei Du, and Ying-Chun Chen,* "Organocatalytic stereoselective Mannich reaction of 3-oxindoles", Org. Lett. 2008, 10, 3583.
137.Tai-Ran Kang, Jian-Wu Xie, Wei Du, Xin Feng, and Ying-Chun Chen,* "Stereoselective desymmetrisation of prochiral ,-dicyanoalkenes via domino Michael-Michael addition reactions", Org. Biomol. Chem. 2008, 6, 2673.
138.Ying-Chun Chen,* an account, "The development of asymmetric primary aminocatalysts based on cinchona alkaloids", Synlett 2008, 1919.
139.Lei Yue, Wei Du, Yan-Kai Liu, Y Ying-Chun Chen,* "Organocatalytic asymmetric direct Michael addition of aromatic ketones to alkylidenemalononitriles", Tetrahedron Lett. 2008, 49, 3881.
140.Yan Zhang, Yan-Kai Liu, Tai-Ran Kang, Ze-Kai Hu, Ying-Chun Chen,* "Organocatalytic enantioselective Mannich-type reaction of phosphorus ylides: Synthesis of chiral N-Boc--amino--methylene carboxylic esters", J. Am. Chem. Soc. 2008, 130, 2456.
2007年
141.Wei Chen, Wei Du, Yong-Zheng Duan, Yong Wu, Sheng-Yong Yang, Ying-Chun Chen,* "Enantioselective 1,3-dipolar cycloaddition of cyclic enones catalyzed by multifunctional primary amine: beneficial effects of hydrogen bonding", Angew. Chem., Int. Ed. 2007, 46, 7667.
142.Tian-Yu Liu, Hai-Lei Cui, Yan Zhang, Kun Jiang, Zhao-Quan He, Bang-Jing Li, Li-Sheng Ding, Ying-Chun Chen,* "Organocatalytic and highly enantioselective direct -amination of aromatic ketones", Org. Lett. 2007, 9, 3671.
143.Tian-Yu Liu, Hai-Lei Cui, Qian Chai, Jun Long, Bang-Jing Li, Yong Wu, Li-Sheng Ding, Ying-Chun Chen,* "Organocatalytic asymmetric Friedel-Crafts alkylation/cascade reactions of naphthols and nitroolefins", Chem. Commun. 2007, 2228.
144.Lin Jiang, Hong-Ting Zheng, Tian-Yu Liu, Lei Yue, Ying-Chun Chen,* "Asymmetric direct vinylogous carbon-carbon bond formation catalyzed by bifunctional organocatalysts", Tetrahedron 2007, 63, 5123.
145.Tian-Yu Liu, Hai-Lei Cui, Jun Long, Bang-Jing Li, Yong Wu, Li-Sheng Ding, Ying-Chun Chen,* "Organocatalytic and highly stereoselective direct vinylogous Mannich reaction", J. Am. Chem. Soc. 2007, 129, 1878.
146.Wei Chen, Wei Du, Lei Yue, Rui Li, Yong Wu, Li-Sheng Ding and Ying-Chun Chen,* "Organocatalytic enantioselective indole alkylations of ,-unsaturated ketones", Org. Biomol. Chem. 2007, 5, 816.
147.Jian-Wu Xie, Lei Yue, Wei Chen, Wei Du, Jin Zhu, Jin-Gen Deng and Ying-Chun Chen,* "Highly enantioselective Michael addition of cyclic 1,3-dicarbonyl compounds to ,-unsaturated ketones", Org. Lett. 2007, 9, 413.
148.Jian-Wu Xie, Wei Chen, Rui Li, Mi Zeng, Wei Du, Lei Yue, Ying-Chun Chen,* Yong Wu, Jin Zhu, and Jin-Gen Deng,* "Highly asymmetric Michael addition of ,-unsaturated ketones catalyzed by 9-amino-9-deoxyepiquinine", Angew. Chem., Int. Ed. 2007, 46, 389.
149.Tian-Yu Liu, Rui Li, Qian Chai, Jun Long, Bang-Jing Li, Yong Wu, Li-Sheng Ding, Ying-Chun Chen,* "Enantioselective Michael addition of -substituted cyanoacetates to vinyl ketones catalyzed by bifunctional organocatalysts", Chem.?Eur. J. 2007, 13, 319.
2006年
150.Wei Chen, Xiang-Hong Yuan, Rui Li, Wei Du, Yong Wu, Li-Sheng Ding, Ying-Chun Chen,* "Organocatalytic and stereoselective [3 + 2] cycloadditions of azomethine imines with ,-unsaturated aldehydes", Adv. Synth. Catal. 2006, 348, 1818.
151.Wei Chen, Rui Li, Yong Wu, Li-Sheng Ding, Ying-Chun Chen,* "Self-supported thiourea-palladium complexe
s: highly air-stable and recyclable catalysts for the Suzuki reaction in neat water", Synthesis 2006, 3058.
152.Lin Jiang, Tong-Fei Wu, Ying-Chun Chen,* Jin Zhu, Jin-Gen Deng,* "Asymmetric transfer hydrogenation catalysed by hydrophobic dendritic DACH-rhodium complex in water", Org. Biomol. Chem. 2006, 4, 3319.
153.Tian-Yu Liu, Jun Long, Bang-Jing Li, Lin Jiang, Rui Li, Yong Wu, Li-Sheng Ding, Ying-Chun Chen,* "Enantioselective construction of quaternary carbon centre catalysed by bifunctional organocatalyst", Org. Biomol. Chem. 2006, 4, 2097.
154.Qing-Ping Liu, Ying-Chun Chen,* Yong-Wu, Jin Zhu, Jin-Gen Deng,* "Self-supported heterogeneous star-shaped oxime-palladacycle catalysts for the Suzuki coupling reaction", Synlett 2006, 1503.
155.Yan-Kai Liu, Rui Li, Lei Yue, Ying-Chun Chen,* Yong Wu, Li-Sheng Ding, "Unexpected ring-opening reactions of aziridines with aldehydes catalyzed by nucleophilic carbenes under aerobic conditions", Org. Lett. 2006, 8, 1521.
156.Jian-Wu Xie, Lei Yue, Dong Xue, Xiao-Li Ma, Ying-Chun Chen,* Yong Wu, Jin Zhu, Jin-Gen Deng,* "Organocatalytic and direct asymmetric vinylogous Michael addition of ,-dicyanoolefins to ,-unsaturated aldehydes", Chem. Commun. 2006, 1563.
157.Wei Chen, Rui Li, Bo Han, Bang-Jing Li, Ying-Chun Chen,* Yong Wu, Li-Sheng Ding, Dan Yang，"Design and synthesis of bis-thiourea ligands and their application in Pd-catalyzed Heck and Suzuki reactions under aerobic condition", Eur. J. Org. Chem. 2006, 1177.
158.Zhi-Quan Yong, Xiao-Ping Xu, Ying-Chun Chen,* Xu Bao, Ling-Ling Weng,* Hu Zheng, "Synthesis and cytotoxic activity of novel water-soluble prodrugs of combretastatin A-4", Chin. Chem. Lett. 2006, 17, 23.
2005年前
159.Dong Xue, Ying-Chun Chen,* Qi-Wei Wang, Ling-Feng Cun, Jin Zhu, Jin-Gen Deng,* "Asymmetric direct vinylogous Michael reaction of activated alkenes to nitroolefins catalyzed by modified cinchona alkaloids", Org. Lett. 2005, 7, 5293.
160.Bang-Jing Li, Lin Jiang, Min Liu, Ying-Chun Chen,* Li-Sheng Ding, Yong Wu, "Asymmetric Michael addition of thiols to ,-unsaturated carbonyl compounds catalyzed by bifunctional organocatalyst", Synlett 2005, 603.
161.Dong Xue, Ying-Chun Chen, Qi-Wei Wang, Xin Cui, Jin Zhu, Jin-Gen Deng, "Transfer hydrogenation of activated C=C bonds catalyzed by ruthenium amido complexes: reaction scope, limitation, and enantioselectivity", J. Org. Chem. 2005, 70, 3584.
162.Ying-Chun Chen,* Tong-Fei Wu, Lin Jiang, Xin Cui, Jin-Gen Deng,* Jin Zhu, Yao-Zhong Jiang, "Synthesis of dendritic ligands and application in asymmetric transfer hydrogenation", J. Org. Chem. 2005, 70, 1006.
163.Chun-Yu Ho, Ying-Chun Chen, Man-King Wong, Dan Yang, "Fluorinated chiral secondary amines as catalysts for epoxidation of olefins with oxone", J. Org. Chem. 2005, 70, 898.
164.Dan Yang,* Ying-Chun Chen, Nian-Yong Zhu, "Sterically bulky thioureas as air- and moisture-stable ligands for Pd-catalyzed Heck reactions of aryl halides", Org. Lett. 2004, 6, 1577.
165.Ying-Chun Chen, Dong Xue, Jin-Gen Deng, Xin Cui, Jin Zhu, Yao-Zhong Jiang, "Efficient asymmetric transfer hydrogenation of activated olefins catalyzed by ruthenium amido complexes", Tetrahedron Lett. 2004, 45, 1555.
166.Pei Nian Liu, Ying-Chun Chen, Xue Qiang Li, Yong Qiang Tu, Jin Gen Deng, "Dendritic catalysts for asymmetric transfer hydrogenation based on (1S,2R)-norephedrine derived ligands", Tetrahedron: Asymmetry 2003, 14, 2481.
167.Ying-Chun Chen, Tong-Fei Wu, Jin-Gen Deng, Hui Liu, Xin Cui, Jin Zhu, Yao-Zhong Jiang, Michael C. K. Choi and Albert S. C. Chan, "Multiple dendritic catalysts for asymmetric transfer hydrogenation", J. Org. Chem. 2002, 67, 5301.
168.Ying-Chun Chen, Tong-Fei Wu, Jin-Gen Deng, Hui Liu, Yao-Zhong Jiang, Michael C. K. Choi and Albert S. C. Chan, "Dendritic catalysts for asymmetric transfer hydrogenation", Chem. Commun. 2001, 1488.
169.Peilian Liu, Yingchun Chen, Jingen Deng, Yongqiang Tu, "Efficient method for the preparation of benzylic bromides", Synthesis 2001, 2078.




编辑：四川大学华西药学院