易培珊，特聘研究员
联系方式：yipeishan[AT]scu.edu.cn
联系地址：四川省成都市武侯区一环路南一段24号四川大学生命科学学院A711（610065）
学术主页：https://scholar.google.com/citations?user=3FyQDV0AAAAJ&hl=en
ORCID：https://orcid.org/0000-0003-4710-8089
学习和工作经历：
2007.09 – 2011.07 北京大学，本科
2011.09 – 2014.07 中国科学院大学，中科院生物物理研究所，硕士，导师：欧光朔
2014.09 – 2017.06 清华大学，博士，导师：欧光朔
2017.10 – 2020.09 名古屋大学(日本)，博士后，导师：五島 剛太(Gohta Goshima)
2020.12 – 至今 四川大学，生命科学学院，特聘研究员
研究方向：
课题组以小立碗藓（Physcomitrium patens）为模型，研究植物细胞分裂与发育的分子机制。小立碗藓是早期陆生植物的代表性分支之一，生长方式包括二维线性（原丝体）和三维多轴向（配子托）形式，是研究植物从水生向陆生过度阶段，细胞分裂与发育模式适应性改变，以及植物重要发育信号通路演化机制的理想系统。小立碗藓具有再生能力强、同源重组效率高、生命周期短、培养简单等特点，在植物学研究中具有独特的优势。近年来，随着基因编辑、正向遗传学筛选和活体细胞成像等技术的发展与应用，小立碗藓已逐渐成为非常有潜力的新兴模式植物。课题组主要结合遗传学、分子生物学、活体细胞成像、生物化学等手段，探索植物细胞生长和分裂模式的调控机制，研究方向包括：
1. 植物细胞极性与不对称分裂
2. 植物细胞的生长、形态发生和维持
3. 细胞骨架和胞内运输
4. 遗传工具的开发与应用
基金项目：
2018 – 2020, The Human Frontier Science Program Long-Term Fellowship
发表文章：(#共同第一作者，*通讯作者)
Yi, P.* and Goshima, G. (2020). Rho of Plants GTPases and cytoskeletal elements control nuclear positioning and asymmetric cell division during Physcomitrella patens branching. Curr. Biol. 30: 2860–2868.
Yi, P.* and Goshima, G. (2020). Transient cotransformation of CRISPR/Cas9 and oligonucleotide templates enables efficient editing of target loci in Physcomitrella patens. Plant Biotechnol. J. 18: 599–601.
Yi, P.* and Goshima, G.* (2018). Microtubule nucleation and organization without centrosomes. Curr. Opin. Plant Biol. 46: 1–7.
Yi, P., Xie, C., and Ou, G.* (2018). The kinases male germ cell-associated kinase and cell cycle-related kinase regulate kinesin-2 motility in Caenorhabditis elegans neuronal cilia. Traffic 19: 522–535.
Yi, P., Li, W.-J., Dong, M.-Q., and Ou, G.* (2017). Dynein-driven retrograde intraflagellar transport is triphasic in C. elegans sensory cilia. Curr. Biol. 27: 1448–1461.
Li, W., Yi, P., Zhu, Z., Zhang, X., Li, W., and Ou, G.* (2017). Centriole translocation and degeneration during ciliogenesis in Caenorhabditis elegans neurons. EMBO J. 36: 2553–2566.
Li, W.#, Yi, P.#, and Ou, G.* (2015). Somatic CRISPR–Cas9-induced mutations reveal roles of embryonically essential dynein chains in Caenorhabditis elegans cilia. J. Cell Biol. 208: 683–692.
Shen, Z., Zhang, X., Chai, Y., Zhu, Z., Yi, P., Feng, G., Li, W., and Ou, G.* (2014). Conditional knockouts generated by engineered CRISPR-Cas9 endonuclease reveal the roles of Coronin in C. elegans neural development. Dev. Cell 30: 625–636.
Yi, P., Li, W.*, and Ou, G.* (2014). The application of transcription activator-like effector nucleases for genome editing in C. elegans. Methods 68: 389–396.
Zhu, Z., Liu, J., Yi, P., Tian, D., Chai, Y., Li, W., and Ou, G.* (2014). A proneural gene controls C. elegans neuroblast asymmetric division and migration. FEBS Lett. 588: 1136–1143.
Feng, G.#, Yi, P.#, Yang, Y.#, Chai, Y.#, Tian, D.#, Zhu, Z., Liu, J., Zhou, F., Cheng, Z., Wang, X., Li, W., and Ou, G.* (2013). Developmental stage-dependent transcriptional regulatory pathways control neuroblast lineage progression. Development 140: 3838–3847.
Cheng, Z.#, Yi, P.#, Wang, X., Chai, Y., Feng, G., Yang, Y., Liang, X., Zhu, Z., Li, W.*, and Ou, G.* (2013). Conditional targeted genome editing using somatically expressed TALENs in C. elegans. Nat. Biotechnol. 31: 934–937.
Wang, X., Zhou, F., Lv, S., Yi, P., Zhu, Z., Yang, Y., Feng, G., Li, W., and Ou, G.* (2013). Transmembrane protein MIG-13 links the Wnt signaling and Hox genes to the cell polarity in neuronal migration. Proc. Natl. Acad. Sci. 110: 11175–11180.